• Journal of the Korean Society for Railway
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• v.16 no.4
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• pp.298-304
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• 2013

This paper systematically analyzes the dynamic effects of structure approaches which are expected to have direct effects on train loads - according to the train's acceleration as the area under consideration is located in a section where acceleration of high speed railway vehicles and the train's operating speed happens. In addition, through an examination of the dynamic train loads, dynamic behavioral characteristics of embedded structures and structure approaches were analyzed and a numerical analysis has been carried out in order to evaluate the performance of track subgrade and the safety of the structure. As a result, we reach the conclusion that the dynamic effects by train loads is low, but somewhat high vertical acceleration occurs.

• Journal of the Korean GEO-environmental Society
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• v.13 no.8
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• pp.25-33
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• 2012

Although it is important to reflect the accurate information of the ground condition in the tunnel design, the analysis and design are conducted by limited information because it is very difficult to consider various geographies and geotechnical conditions. When the tunnel is under construction, examination of accurate safety and prediction of behavior are overcome the limits of predicting behavior by Artificial Neural Network in this study. First, construct the suitable structure after the data of field was made sure by the multi-layer back propagation, then apply with algorithm. Employ the result of measured data from database, and consider the influence factor of tunnel, like supporting pattern, RMR, Q, the types of rock, excavation length, excavation shape, excavation over, to carry out the reliable analysis through field applicability of Artificial Neural Network. After studying, using the ANN model to predict the shearing displacement, convergence displacement, underground displacement, Rock bolt output follow the excavation over of tunnel construction field, then determine the field applicability with ANN through field measured value and comparison analysis when tunnel is being constructed.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.19 no.9
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• pp.2100-2106
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• 2015

Recently, we are increasing an interest of the health care from the developing elderly society. The need for the safety standardization is the High-tech industry that the technology of Medical science based on advanced nations with the wireless communication technology. It is urgent matter the chronic disease that is growing the total costs is everyday increased. We consider the standardization of the monitoring the medical examination based on the medical science environment with wireless communication technology. In addition, we make the environment of the powerful nation based on medical / patient care technology for the supporting of the high quality service. In this paper, we focus on description of the relationship that convergence of the medical / patient care science is need the component based on wireless communication technology.

• Journal of Pharmaceutical Investigation
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• v.34 no.4
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• pp.299-303
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• 2004

Prescription filling in powder form is performed in community pharmacy practice to adjust dose for children and patients who cannot swallow whole tablet. However, there are few reports regarding the stability of the active ingredient and possible microbial growth after the medication is dispensed to powder form. This study examined the stability of atenolol, an antihypertensive agent, and microbial growth in the unit dose pouches dispensed at twenty-one community pharmacies located in Taegu area. Randomly chosen first unit dose pouch contained 77.4% of the prescribed dose of the drug and there were only four community pharmacies that dispensed the drug within 10% deviation from the dose prescribed by physician. Surprisingly, there were three community pharmacies that dispensed the drug with greater than 40% deviation, which may pose a major concern regarding the efficacy and safety of the drug prescribed for the treatment of hypertension. Atenolol content during a month did not indicate significant change, showing 5.4%, 4.3%, and 3.3% of decrease in 50%, 80%, and 90% relative humidity conditions, respectively. Microbiological examination during a month showed less than 0.5 microorganism in high power field (hpf) in all the relative humidity conditions tested. Based on this study, pharmacy practice in community pharmacy needs to be rigorously regulated to ensure that the dose of the prescribed drug is properly incorporated into the unit dose pouch dispensed as powder form.

• Journal of Pharmaceutical Investigation
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• v.37 no.6
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• pp.403-411
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• 2007

The importance of pharmaceutical additives is increasing and the sorts and application categories are being classified in detail. International pharmaceutical council based on IPEC-America, IPEC-Europe and JPEC was established for specifications, safety and efficacy, approval regulations of pharmaceutical additives in 1992. Therefore, scrutinized examination of pharmaceutical additives used for already approved domestic drug was performed under the supervision of KFDA and nomenclature on application categories of pharmaceutical additives was summarized and endowed their glossary. Additionally, the boundaries of pharmaceutical additives according to the dosage forms based on the principle of the dosage forms of Korean pharmacopoeia were classified. These informations could be available for standards & experimental methods, approval, evaluation, audit of drug and contribution for national welfare.

• Korean Security Journal
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• no.29
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• pp.87-113
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• 2011

Korean security industry has history of more than half a century, and it is growing fast. Private security industry contributes not only to livelihood safety, but also to national security. The area of the industry is being expanded. Security Act is closely related to the security industry, and has contributed to the growth of private security industry sector. Security Act of Korea, which was established in 1976, was originally made after Japanese Security Act. But nowadays, Korean Security Act is as systematic as the Japanese act. However, for 10 years, Security Act of Korea has been stagnant, not able to reflect security industries' demand. The writer has contributed to the development of Security Act. In 1995, the writer wrote the basic framework of Security Instructor Qualifications System and drafted Security Act in 2002. There are currently many problems in existing Security Act, but there are four representative problems. (1) No more establishment of new security sector, (2) excessively slack qualification criteria, (3) the education system for guards, (4) the security Instructor examination system. This paper derives problems of current Security Act, and suggests solutions for them. Not only the academic world, but all of us should pay attention to the revision of Security Act.

• Tunnel and Underground Space
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• v.18 no.4
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• pp.289-299
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• 2008

Based on the case study on the causes for the failure of cutting slope composed of weathered rock and soil, the factors influencing the design of a cutting slope have been examined, This type of rock and soil is widely distributed on the region whose parent rock is granite. To analyze the stability of the cutting slope, the following series of progress has been conducted: (1) ground characterization by geological survey and ground investigation, (2) the safety factor examination by limit equilibrium analysis and numerical analysis and (3) the comparison and analysis of rainfall and failure history. As a result, the main factors to cause the failure is determined to be the decrease of shear strength in the upper parts whose ground condition is weakened during localized heavy rain. Moreover, the analysis indicates the failure is also closely related to the groundwater inflow path. On the base of this investigation, a reinforcement method is proposed to ensure the stability of the cutting slope.

• Journal of Korean Neurosurgical Society
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• v.47 no.3
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• pp.180-184
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• 2010

Objective : To prevent temporal depression after the pterional craniotomy, this study was designed to examine the safety and aesthetic efficacy of the brushite calcium phosphate cement (CPC) in the repair and augmentation of bone defects following the pterional craniotomy. Methods : The brushite CPC was used for the repair of surgically induced cranial defects, with or without augmentation, in 17 cases of pterional approach between March, 2005 and December, 2006. The average follow-up month was 20 with range of 12-36 months. In the first 5 cases, bone defects were repaired with only brushite CPC following the contour of the original bone. In the next 12 cases, bone defects were augmented with the brushite CPC rather than original bone contour. For a stability monitoring of the implanted brushite CPC, post-implantation evaluations including serial X-ray, repeated physical examination for aesthetic efficacy, and three-dimensional computed tomography (3D-CT) were taken 1 year after the implantation. Results : The brushite CPC paste provided precise and easy contouring in restoration of the bony defect site. No adverse effects such as infection or inflammation were noticed during the follow-up periods from all patients. 3D-CT was taken 1 year subsequent to implantation showed good preservation of the brushite CPC restoration material. In the cases of the augmentation group, aesthetic outcomes were superior compared to the simple repair group. Conclusion : The results of this clinical study indicate that the brushite CPC is a biocompatible alloplastic material, which is useful for prevention of temporal depression after pterional craniotomy. Additional study is required to determine the long-term stability and effectiveness of the brushite calcium phosphate cement for the replacement of bone.

• The Journal of Korean Obstetrics and Gynecology
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• v.20 no.3
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• pp.213-228
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• 2007

Purpose: This master‘s thesis to evaluate the grade of life after medication a Dangguijakyak-san(pasabu) and Gyejibongnyeong-hwan(cheongwal) with in postmenopausal women get lowering quality of life caused by vasomotor symptoms with hot flush. Methods: A subject who signing on the clinical trial written consent by self-will is registered this clinical trial after decided suitable by selection and exception standard, after take a medical experiment and checkup according to clinical trial plan. Registered subject should valuated by settled schedule after take the testing medicine 1,2 during thirty-day. In this period, a subject allocated at relatively better suited experimental group by oriental doctor after consideration of general efficacy and nature of a medicine at second visiting. Results: The result of comparison in the remedial value with sixteen patients who ended the experiment is like next list. 1. There's no regarded difference of comparison in general conditions between two patient groups. 2. There's no regarded difference during observation period before take medicine. 3. By period of measurement, there's something regarded differences most of patients of two parts after taking medicine. 4. There's no regarded difference at alteration phase of each standard according to kind of medicine. 5. There's no abnormal views reflected at allergy, Laboratory and Physical Examination during experiment. Conclusion: This experiment evidence a Dangguijakyak-san and Gyejibongnyeong-hwan can help for improvement generally life quality of postmenopausal women and certify safety of herbs.

• Journal of Veterinary Science
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• v.22 no.3
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• pp.31.1-31.12
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• 2021

Background: Blackened intestines in slaughtered pigs have been commonly observed in China in recent years. However, no cause has been reported. Objectives: We attempted to determine whether the blackening of the pig intestine was related to an excess of copper (Cu) in their feed. Methods: In this study, we observed and collected porcine intestines in small- and large-scale pig slaughterhouses in Shandong province from May to October 2018. Twelve types of metal ions were detected in the black intestinal samples. Results: The Cu level in the intestine samples was mostly higher than the Chinese national limit for food. Further study showed that Cu supplementation in most commercial porcine feed also exceeded the national standard. An animal model (mouse) that could mimic the intestinal blackening in pigs was established. Compared to control mice, Cu accumulated in the liver and intestines of mice fed an excessive Cu level, confirming the excessive Cu in the feed may be considered the major cause of blackened porcine intestines. Microscopic examination revealed that black intestines had many particles containing Cu in the lamina propria of the intestinal mucosa, and the intestinal mucosal epithelial cells showed degeneration and necrosis. Conclusions: In conclusion, overuse of Cu in animal feed can lead to animal poisoning and Cu accumulation in animal products. Such overuse not only harms the health of livestock but can also affect public health.