• Title/Summary/Keyword: safety benefits

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국제거래(國際去來)에 있어서의 제조물책임(製造物責任)과 그 대응(對應)

  • Gang, Lee-Su
    • Journal of Arbitration Studies
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    • v.10 no.1
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    • pp.92-113
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    • 2000
  • Products liability refers to the liability of any or all parties along the chain of manufacture of any product for damage caused by that product. This includes the manufacturer of component parts (at the top of the chain), an assembling manufacturer, the wholesaler, and the retail store owner (at the bottom of the chain). Products containing inherent defects that cause harm to a consumer of the product, or someone to whom the product was loaned, given, etc., are the subjects of products liability suits. The goal of products liability system should be to maximize consumer welfare by efficiently providing just compensation for injuries incurred and deterring future injuries without unreasonably impeding the supply of the goods and services to consumers. Some advanced countries, apart from relying on products liability systems, also apply other policies and legislation directly aimed at the safety of the consumer. The application of general safety policies as well as products liability rules is not costless. An efficient system will not eliminate risk from society. An efficient system ... that maximises consumer welfare ... maximises the benefits while minimising the costs. Products liability claims can be based on negligence, strict liability, or breach of warranty of fitness depending on the jurisdiction where the claim is based. In view of international business and law circumstances, it should be stressed that international enterprises in Korea should consider how to cope with the situation of international transaction. International enterprises should have a correct perception about products liability which is to contribute the stabilization and improvement of the people's life and the sound develpement of the national economy. Products liability system creates incentives that influence behaviour and performance in ways that are desirable, such as more diligent monitoring to prevent defective products from reaching the market-place. At the same time, any liability system will impose burdens that are undesirable, such as greater costs imposed on business and consumers and reduced avaiability of consumer goods. The concern for society is to balance. The ideal situation is where the cost imposed on producers of goods and services pushes them to a desirable level of care but not so far that producers reach undesirable level of caution that may deprive consumers unnecessarily of the benefits from new and innovative products.

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Efficacy and Safety of Selumetinib Compared with Current Therapies for Advanced Cancer: a Meta-analysis

  • Shen, Chen-Tian;Qiu, Zhong-Ling;Luo, Quan-Yong
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.5
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    • pp.2369-2374
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    • 2014
  • Background and Aim: Selumetinib is a promising and interesting targeted therapy agent as it may reverse radioiodine uptake in patients with radioiodine-refractory differentiated thyroid cancer. We conduct this metaanalysis to compare the efficacy and safety of selumetinib with current therapies in patients with advanced cancer. Methods: An electronic search was conducted using PubMed/ Medicine, EMBASE and Cochrane library databases. Statistical analyses were carried out using either random-effects or fixed-effects models according to the heterogeneity of eligible studies. Results: Six eligible trials involved 601 patients were identified. Compared with current therapies, treatment schedules with selumetinib did not improve progression free survival (hazard ratio, 0.91; 95%CI 0.70-1.17, P= 0.448), but did identify better clinical benefits (odds ratio, 1.24; 95%CI 0.69-2.24, P = 0.472) and less disease progression (hazard ratio, 0.72; 95%CI 0.51-1.00, P = 0.052) though its impact was not statistically significant. Sub-group analysis resulted in significantly improved progression free survival (hazard ratio, 0.61; 95%CI 0.49-0.57, P = 0.00), clinical benefits (odds ratio, 3.04; 95%CI 1.60-5.77, P = 0.001) and reduced disease progression (hazard ratio, 0.35; 95%CI 0.18-0.67, P = 0.001) in patients administrated selumetinib. Dermatitis acneiform (risk ratio, 9.775; 95%CI 3.143-30.395, P = 0.00) and peripheral edema (risk ratio, 2.371; 95%CI 1.690-3.327, P = 0.00) are the most frequently observed adverse effects associated with selumetinib. Conclusions: Compared with current chemotherapy, selumetinib has modest clinical activity as monotherapy in patients with advanced cancer, but combinations of selumetinib with cytotoxic agents in patients with BRAF or KRAS mutations hold great promise for cancer treatment. Dermatitis acneiform and peripheral edema are the most frequently observed adverse effects in patients with selumetinib.

Proximal Gastrectomy for Gastric Cancer

  • Jung, Do Hyun;Ahn, Sang-Hoon;Park, Do Joong;Kim, Hyung-Ho
    • Journal of Gastric Cancer
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    • v.15 no.2
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    • pp.77-86
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    • 2015
  • Laparoscopic proximal gastrectomy (LPG) is theoretically a superior choice of minimally-invasive surgery and function-preserving surgery for the treatment of proximal early gastric cancer (EGC) over procedures such as laparoscopic total gastrectomy (LTG), open total gastrectomy (OTG) and open proximal gastrectomy (OPG). However, LPG and OPG are not popular surgical options due to three main concerns: the first, oncological safety; the second, functional benefits; and the third, anastomosis-related late complications (reflux symptoms and anastomotic stricture). Numerous recent studies have concluded that OPG and LPG present similar oncological safety profiles and improved functional benefits when compared with OTG and LTG. While OPG with modified esophagogastrostomy does not provide satisfactory results, OPG with modified esophagojejunostomy showed similar rates of anastomosis-related late complications when compared to OTG. At this stage, no standard reconstruction method post-LPG exists in the clinical setting. We recently showed that LPG with double tract reconstruction (DTR) is a superior choice over LTG for proximal EGC in terms of maintaining body weight and preventing anemia. However, as there is no definitive evidence in favor of LPG with DTR, a randomized clinical trial comparing LPG with DTR to LTG was recommended. This trial, the Korean Laparoscopic Gastrointestinal Surgery Study-05 (NCT01433861), is expected to assist surgeons in choice of surgical approach and strategy for patients with proximal EGC.

A Study on Success Model of Internet Banking (인터넷뱅킹 성공모형에 관한 연구)

  • Lee, Kyeung-Keun
    • Journal of the Korea Society of Computer and Information
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    • v.12 no.5
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    • pp.243-251
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    • 2007
  • The purpose of this study propose and empirically assessed Internet Banking success model. This was derived through an analysis of the quality evaluation factors of Internet Banking services and review of TAM model, IS success model, e-Commerce success model literature. The research model consists of exogenous variables(ease of use, economic benefits, safety) and endogenous variables (usefulness, user satisfaction, trust, behavioral intention to use). The analysis results revealed that ease of use is a very significant factor influencing usefulness and user satisfaction, trust. Safety is a significant factor influencing trust. Economic benefits and usefulness, trust are significant factors influencing user satisfaction. Usefulness and user satisfaction are significant factors influencing behavioral intention to use. This study provide the initiative of Internet Banking success model. Internet banking firms will support the competitive service through strategic qualify evaluation and improvement using Internet Banking success model.

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The Effectiveness of Facilitation Education for Call Quality of Medical Representative in Pharmaceutical Industry (제약회사 영업사원의 면담 품질(Call Quality) 향상을 위한 퍼실리테이션(Facilitation) 교육법의 효과)

  • Im, Hyung Sik;Kang, Shin Kook;Lee, Kwang-Su;Hong, Jin Tae
    • The Korean Journal of Health Service Management
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    • v.13 no.4
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    • pp.215-228
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    • 2019
  • Objectives: The purpose of this study is to figure out that Facilitation education can affect significant improvement in sales staff's understanding of precise pharmacokinetics, benefits, safety, and side effects, etc. and eventually lead to increase in call after taking courses. Methods: Data utilized in this study was collected from 413 sales staffs who completed Facilitation course for 5 months. This study used statistical methodologies, paired t-test, exploratory factor analysis, and logistic regression model in order to identify change in Call and after Facilitation courses. Results: The result shows that there are statistically significant increases in CALL quality after Facilitation courses based on the result of pared t-test. Moreover, Facilitation education is more effective in average time of one-time detail than average number of visits per day and average number of doctors per day from the result of logistic regression. Conclusions: In order for MR in pharmaceutical company to improve CALL quality, the education for precise pharmacokinetics, benefits, safety, and side effects is necessary. In addition, various professional training required for detail, including disease education, Selling Skills education, and literacy education are essential. Therefore, Facilitation education would be desirable choice in terms of pharmaceutical marketing strategy.

APPLICATION OF FIRE RESEARCH TO BUILDING FIRE SAFETY DESIGN - CURRENT BENEFITS AND FUTURE NEEDS

  • Bressington, Peter;Johnson, Peter
    • Proceedings of the Korea Institute of Fire Science and Engineering Conference
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    • 1997.11a
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    • pp.392-403
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    • 1997
  • There is a strong international move towards performance based fire regulations for buildings with New Zealand and Australia at the forefront of research in this fold. The reform of regulations is thought to offer more innovation and flexibility in building design and greater cost effectiveness in construction. An important part of the research in this area is related to the development of agreed approaches to fire safety design, such as the Fire Code Reform Centre's "Fire Engineering Guidelines" or New Zealand's "Fire Engineering Design Guide". Such design process documents have incorporated or referenced much of the latest research in areas such as: tenability criteria fire compartment models egress models risk assessment. Use of such design guidelines or equivalents in major projects in countries such as Hong Kong and Australia have highlighted where fro engineering can offer real benefits to building designers and ultimately building owners and operators. However, there is still much research to be done and use of a systematic, logical design approach clearly identifies where design data or modelling techniques are still urgently required. Such areas are: fire growth rates and peak heat release rates for non-residential occupancies pre-movement times related to egress experimental validation and limits of applicability of CFD and other compartment Ire models probability/reliability data on fire protection systems for risk based analysis. Examples from case studies will be shown where lack of such research and poor judgement can lead to inferior design solutions or where unnecessarily conservative designs can lead to cost excesses. In summary, the link between Ire engineering designers and the research community is very important to highlight areas of fire research that will have the most benefit to the building and construction industry.nstruction industry.

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Economic Feasibility and Basic Technical Requirements for Tube Transportation System (튜브운송시스템 경제성과 성능요구조건)

  • Lee, Jin-Sun;Lim, Kwan-Su;Nam, Doo-Hee;Kwon, Hyuk-Bin;Kim, Jung-Yeol
    • Journal of the Korean Society for Railway
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    • v.11 no.5
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    • pp.513-518
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    • 2008
  • Currently, urban areas face congestion problems that diminish personal mobility and freight-transport productivity. An increasing number of experts suggest that separating freight traffic from passenger traffic makes sense in terms of economics, the environment, and safety. Some experts suggest that tube transportation is the solution. The objective of this paper is to evaluate the potential benefits and limitations of tube transportation system as a viable mode of transport that can alleviate congestion on roadways. Specifically, this research employs theoretical and practical method identifying, evaluating, and selecting appropriate freight pipeline systems; evaluating the technical and economic feasibility of tube transportation; and estimating environmental, energy, and safety benefits.

Cost-benefit Analysis on Occupational Reference Levels for Radon (지각방사선(라돈) 참조준위별 저감 대책에 따른 비용 편익 분석)

  • Choi, Eun-Hi;Chung, Eun Kyo;Kim, Su-Geun;Jung, Myung-Hee
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.29 no.1
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    • pp.57-68
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    • 2019
  • Objective: The purpose of this study is to propose the benefits of reduction measures according to the occupational radon reference level in order to present basic data for radon management guidelines considering domestic circumstances. Methods: This study uses radon data measured in the subway stations from 2015 to 2016. Of the total of 4,643 cases, 4,231 cases were analyzed excluding the 412 cases where the values were below $300Bq/m^3$. Results: Cost-Benefit analysis was done on the results of the field survey on subway work sites. At the exposure level of $400Bq/m^3$, the ratio between the cost and the benefit was highest at 1 : 1.81(the cost was KRW 1,398,568,032, while the benefit KRW 2,5248,772,841). At the exposure level of $600Bq/m^3$, the ratio of cost and benefit was 1: 1.80, at $300Bq/m^3$ it was 1.72, at $800Bq/m^3$ it was 1.71, at $200Bq/m^3$ it was 1.54, and at $100Bq/m^3$ it was 1.40. Conclusions: Radon management in the workplace provides economic benefits and appropriate reduction strategies are needed. In addition, it is necessary to establish and distribute radon exposure assessment procedures and guidelines for the safety and health of employees when exceeding the exposure standard, and guidelines for radon management in the workplace should be established.

A Study on the Subjectivity of Customers Using the Big Blur Phenomenon and Kiosk Introduction (외식업체 빅 블러(Big Blur)현상과 키오스크(Kiosk)도입에 따른 이용고객의 주관성 연구)

  • Kim, Chan-Woo;Shin, Seoung-Hoon
    • The Journal of the Korea Contents Association
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    • v.19 no.5
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    • pp.268-279
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    • 2019
  • This study applied the Q methodology to the graduate students of the department of food service management in Seoul to grasp the subjective perception of customers using the big blur phenomenon and the introduction of the kiosk. As a result of the analysis, five types were derived. (N = 6): Fast payment and various order preference types, the second type (N = 6): Earning and discount benefits preference type, the third type (N = 3): Simple order preference type, The fourth type (N = 2): Employee service preference type, and the fifth type (N = 3): Safety payment preference type. In the future, the research on the Big Blur phenomenon of eating out company will be refined through more detailed Q methodological questions with analytical techniques based on extensive literature and empirical studies, and to analyze the various opinions of respondents more concretely and objectively.

Acupuncture for Symptomatic Rotator Cuff Disease: A Systematic Review and Meta-Analysis

  • Choi, Seoyoung;Lee, Jisun;Lee, Seunghoon;Yang, Gi Young;Kim, Kun Hyung
    • Journal of Acupuncture Research
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    • v.38 no.1
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    • pp.20-31
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    • 2021
  • The objective was to evaluate the effectiveness and safety of acupuncture for patients with rotator cuff diseases. There were 12 electronic databases and 3 trial registries searched up to November 30th, 2019. All randomized trials were eligible, regardless of language, date of publication, or settings. The primary outcomes were pain, shoulder function, and proportion of improved participants assessed within 12 weeks of randomization of the trial. The Cochrane risk of bias for the studies was assessed. Effects sizes were presented as a risk ratio, mean difference, or standardized mean difference with a 95% confidence intervals. Grading of Recommendations Assessment, Development and Evaluation approach was adopted to rate certainty of evidence. Of the 3,686 records screened, 28 randomized trials (2,216 participants) were included in this review. The types of acupuncture included manual acupuncture, dry needling, electroacupuncture, acupotomy, warm needle acupuncture, and fire needle acupuncture. All of the studies had an unclear or high risk of bias related to more than 1 domain. Significant benefits of acupuncture in terms of pain and shoulder function were observed in all comparisons, however, the proportion of improved participants was not described in 2 comparisons. There was substantial heterogeneity among meta-analyzed trials. No serious harm was observed. For primary outcomes, the overall certainty of evidence was very low. There was very low certainty of evidence for the benefits of acupuncture for patients with rotator cuff diseases. The safety of acupuncture remains unclear due to the incompleteness of reporting. Future well-designed randomized trials with transparent reporting are required.