• Title/Summary/Keyword: safety D/B

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Creep of Plate Anchors Embedded in Bentonite (Bentonite에 근입된 앵커의 Creep 특성)

  • Shin, B.W.;Lee, J.D.;Shin, J.H.;Lee, B.J.
    • Journal of the Korean Society of Safety
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    • v.10 no.4
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    • pp.3-8
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    • 1995
  • Anchors find their use in providing tie-back resistance for submerged footings, transmission towers, tunnels and ocean structures. Laboratory model teats were performed for the short-term net ultimate uplift capacity of a circular anchors with respect to various embedment depths and moisture content in saturated bentonite. The tests have been conducted with the anchor at two different moisture contents. Based an the model test results, empirical relationships between the net load, rate of strain, and time have been developed. Test results are as follows. 1) In creep tests for load versus ultimate uplift capacity, the displacement of plate anchors rapidly increases during the primary stage but thereafter becomes constant over a period of time. 2) Displacement increased with the increase of the sustain load and embedded ratio in soil. 3) If the load is less than or equal to 75% of the short-term ultimate uplift capacity, a complete pullout does not occur due to creep.

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An evaluation of Fatigue Crack Propagation Behaviors on Cyclic Overload Test (반복과대하중에 의한 피로파괴거동의 고찰)

  • 김용수;신근하;강동명;김병석
    • Journal of the Korean Society of Safety
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    • v.7 no.2
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    • pp.47-56
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    • 1992
  • The retardation effect of fatigue crack propagation after cyclic overloading seems to be affected by strain hardening exponent. Namely, for the material with high values of n, the delay effect is found to be severe. We proposed a modified crack retardation equation which may apply the retardation of fatigue crack growth after a cyclic overloading, as (da/dN)'$_{cyc}$=($\mu$n+λ)B $\Delta$ $K^{q}$ /[(1- $R_{eff}$) $K_{cf}$$\Delta$K]. where, $R_{eff}$ is effective stress ratio [=( $K_{min}$-K, os)/( $K_{max}$$K_{res}$)] The constants $\mu$=-0.5 and λ=0.6, and the values are found to be identical for materials such as aluminum (A 1060), steel (SS 34), brass ( $B_{s}$ SIB) and stainless steel (SUS 304) used in this investigation. (SUS 304) used in this investigation.ation.n.n.

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Research of Developing of Standards for Electronic Thermometers (전자식체온계 기준규격 개발 연구)

  • Kim, E.J.;Lee, M.J.;Lee, B.Y.;Park, K.G.;Kim, D.S.;Lee, I.S.;Park, H.D.;Jeong, H.K.
    • Journal of Biomedical Engineering Research
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    • v.31 no.2
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    • pp.123-128
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    • 2010
  • The thermometers is widely used in diagnostic medical devices, and the safety and accurate performance of these devices are important in the diagnosis and monitoring of personal health. Especially, the accuracy of infra-red thermometer is highly emphasized. Here two typical thermometers are utilized for this purpose: the electronic thermometers measure body temperature by contacting to subject while infra-red thermometers measure by no contacting to subject. Therefore, the evaluating items of each thermometer are different, and the standard for each temperature is highly needed. But, there have been no international standards of each thermometer such as IEC. In this paper, we developed the standards of electronic and infra-red thermometer based on national standards such as KS, ASTM, EN, JIS and FDA guidance. The new standards focused on the safety and suitable performance for health care. This standards were applied to enact and revise the electronic medical device standards. So it can be applied to evaluate the safety and performance on technical file review. We predict that this standard will improve the quality of diagnostic medical devices (thermometers) and increase the international competitive power of domestic product.

Comparison of Clinical Results of Excimer Laser Correction of Myopia and Compound Myopic Astigmatism Using VISX 20/20B $VisionKey^{TM}$ (VISX 20/20B $VisionKey^{TM}$ 엑시머레이저의 version 4.01 software를 이용한 근시교정술 및 근시성난시교정술의 임상성적 비교)

  • Lee, Sang-Bumm;Bae, Sang-Bok
    • Journal of Yeungnam Medical Science
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    • v.17 no.1
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    • pp.55-65
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    • 2000
  • Purpose: To compare the efficacy, predictability, stability and safety of excimer laser photorefracive keratectomy(PRK) for myopia and photoastigmatic refractive keratectomy(PARK) for compound myopic astigmatism. Methods: Two-hundred and three eyes(l18 eyes < -7D spherical equivalent, 85 eyes ${\geq}$ -7D spherical equivalent) received excimer laser correction for compound myopic astigmatism and 152 eyes(116 eyes < -7D, 36 eyes ${\geq}$ -7D) for simple myopia. A VISX 20/20B $VisionKey^{TM}$ excimer laser was used to perform either PARK or PRK. Visual acuity with and without correction, refraction, IOP, corneal haze, and topography were evaluated at 1, 3, 6, and 12 months postoperatively. All patients were followed up for more than 12 months. Results: Postoperative refraction were generally stable after 3 months without significant early overcorrection. At 12 months, 110(94.8%) eyes that underwent PRK and 104(88.1%) eyes that underwent PARK achieved UCVA of 20/30 or better in the group who had lower than -7D correction. For eyes treated with -7D or more, these figures were 31(86.1%) eyes after PRK and 57(67.1%) eyes after PARK. The incidences of within 1D of plano refraction at 1 year follow-up were 97.4% after PRK and 93.2% after PARK in the group who had lower than -7D correction. For eyes treated with -7D or more, these figures were 80.6% after PRK and 70.6% after PARK. Conclusions Myopia with or without astigmatism was successfully treated in most of the eyes using PRK or PARK with VISX 20/20B $VisionKey^{TM}$ excimer laser. The predictability and stability of the postoperative refraction during the first 12 months seem to be quite reliable. Further improvement of excimer laser system and software should increase the clinical outcomes and safety of refractive procedures.

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Numerical Analysis of Electromagnetic Characteristic of High Voltage/Current Cable for Fuel Cell Electric Vehicle (FCEV) (수소 연료전지 차량용 고전압 케이블의 전자파 특성 수치해석에 관한 연구)

  • Lee, Soon-Yong;Choi, Jae-Hoon
    • Journal of Hydrogen and New Energy
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    • v.21 no.3
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    • pp.149-157
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    • 2010
  • The electromagnetic characteristics of FCEVs (fuel cell electric vehicles) are much different from the existing combustion engine cars as well as hybrid, plug-in-hybrid, and pure electric vehicles due to the high voltage/current generated by a fuel cell stack which uses a compressed hydrogen gas reacted with oxygen. To operate fuel cell stack efficiently, BOP (Balance of Plant) is essential. BOP systems are used many not only for motors in water pump, air blower, and hydrogen recycling pump but also inverters for these motors. Since these systems or components are connected by high voltage cables, EMC (Electromagnetic compatibility) analysis for high voltage/current cable is the most important element to prevent the possible electric functional safety errors. In this paper, electromagnetic fields of high current/voltage cable for FCEVs is studied. From numerical analysis results, time harmonic magnetic field strength of high current/voltage cable have difference of 20~28 dB according to phase. EMI result considered ground effect of FECV at 10 m shows difference of 14.5 dB at 30 MHz and 2.8 dB at 230 MHz compared with general cable.

Thymol Ameliorates Aspergillus fumigatus Keratitis by Downregulating the TLR4/ MyD88/ NF-kB/ IL-1β Signal Expression and Reducing Necroptosis and Pyroptosis

  • Limei Wang;Haijing Yan;Xiaomeng Chen;Lin Han;Guibo Liu;Hua Yang;Danli Lu;Wenting Liu;Chengye Che
    • Journal of Microbiology and Biotechnology
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    • v.33 no.1
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    • pp.43-50
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    • 2023
  • Fungal keratitis is a refractory kind of keratopathy. We attempted to investigate the antiinflammatory role of thymol on Aspergillus fumigatus (A. fumigatus) keratitis. Wound healing and fluorescein staining of the cornea were applied to verify thymol's safety. Mice models of A. fumigatus keratitis underwent subconjunctival injection of thymol. The anti-inflammatory roles of thymol were verified by hematoxylin-eosin (HE) staining, slit lamp observation, quantitative real-time polymerase chain reaction (qRT-PCR), and Western blotting. In contrast with the DMSO group, more transparent corneas and less inflammatory cells infiltration were detected in mice treated with 50 ㎍/ml thymol. Thymol downregulated the synthesis of TLR4, MyD88, NF-kB, IL-1β, NLRP3, caspase 1, caspase 8, GSDMD, RIPK3 and MLKL. In summary, we proved that thymol played a protective part in A. fumigatus keratitis by cutting down inflammatory cells aggregation, downregulating the TLR4/ MyD88/ NF-kB/ IL-1β signal expression and reducing necroptosis and pyroptosis.

Development of Inverter for Elevator Door Control (엘리베이터 자동문제어 인버터 개발)

  • Kim, J.K.;Choi, U.D.;Jung, M.K.;Choi, S.K.;Yun, J.H.;Han, S.B.
    • Proceedings of the KIEE Conference
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    • 1995.07a
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    • pp.308-310
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    • 1995
  • Most of the elevator door controllers have been controlled by DC Motors as an actuator. Recently, The control system using AC induction motor and general purpose inverter has been applied to control of elevator door. But there are some difficulties in making use of this system, such as adjustment of door speed pattern, door open-close time, and security of passenger safety. In order to solve these problems, a special inverter has, been developed with an encoder feedback. From the result of field-test, we proved that a special inverter with encoder feedback device has come to considerable effect. Until now about 1,200 sets of these inverters are operated in Korea and about 100 sets are operated in South-east Asia.

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Mathematical modeling of growth of Escherichia coli strain RC-4-D isolated from red kohlrabi sprout seeds (적콜라비 새싹채소 종자에서 분리한 Escherichia coli strain RC-4-D의 생장예측모델)

  • Choi, Soo Yeon;Ryu, Sang Don;Park, Byeong-Yong;Kim, Se-Ri;Kim, Hyun-Ju;Lee, Seungdon;Kim, Won-Il
    • Food Science and Preservation
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    • v.24 no.6
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    • pp.778-785
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    • 2017
  • This study was conducted to develop a predictive model for the growth of Escherichia coli strain RC-4-D isolated from red kohlrabi sprout seeds. We collected E. coli kinetic growth data during red kohlrabi seed sprouting under isothermal conditions (10, 15, 20, 25, and $30^{\circ}C$). Baranyi model was used as a primary order model for growth data. The maximum growth rate (${\mu}max$) and lag-phase duration (LPD) for each temperature (except for $10^{\circ}C$ LPD) were determined. Three kinds of secondary models (suboptimal Ratkowsky square-root, Huang model, and Arrhenius-type model) were compared to elucidate the influence of temperature on E. coli growth rate. The model performance measures for three secondary models showed that the suboptimal Huang square-root model was more suitable in the accuracy (1.223) and the suboptimal Ratkowsky square-root model was less in the bias (0.999), respectively. Among three secondary order model used in this study, the suboptimal Ratkowsky square-root model showed best fit for the secondary model for describing the effect of temperature. This model can be utilized to predict E. coli behavior in red kohlrabi sprout production and to conduct microbial risk assessments.

A study on Requirements of the Test Flight Safety for a 350m Unmanned Airship (50m급 무인비행선 시험비행 안전성 요구사항에 관한 연구)

  • Jeong, B.G.;Shin, D.W.
    • Journal of the Korean Society for Aviation and Aeronautics
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    • v.12 no.2
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    • pp.1-15
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    • 2004
  • In this study, we analyze technical requirements for a 50m unmanned airship order to assure safety in the test flight operation. The 50m class unmanned airship developed by Airship Group in Korea Aerospace Research Institute(KARI). The 50m class unmanned airship was developed as a scale-down model of 200m class stratosphere unmanned airship. This study reviews specifications and characteristics of 50m class unmanned airship and develops Airworthiness Requirements on the basis of current effective Aviation Act, Airworthiness standards, and relevant international documents. The developed requirements can be applied to the safety assessment of the 200m class stratosphere unmanned airship.

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Induction of Hepatic Microsomal Cytochrome P450 by N,N-dimethylformamide in Sprague-Dawley Rats (흰쥐에서 N,N-dimethylformamide에 의한 간장의 Microsomal Cytochrome P450의 유도)

  • Koh, Sang-Baek;Cha, Bong-Suk;Kang, Seung-Kyu;Joung, Hyo-Seok;Kim, Ki-Woong
    • Journal of Preventive Medicine and Public Health
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    • v.32 no.1
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    • pp.88-94
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    • 1999
  • Objectives. In order to gain a better understanding of the mechanism of DMF toxicity, recent studies have focused on hepatic drug metabolizing enzymes. In this study, we investigated the effects of DMF on the induction of P450 and the activities of other related enzymes in rat liver microsomes. Methods. DMF was administered to male Sprague Daweley rats by intraperitoneal injection at 0(control), 450(D1), 900(D2), 1,800(D3) mg DMF/kg body weight in olive oil once a day for three days. Hepatic P450 was measured by method of Omura and Sato. We evaluated selective assays for the three drug metabolizing cytochrome P450 isoenzymes 1A1, 2B1 and 2E1. Results. The content of microsomal protein, P450 and b5 were tended to be decreased in DMF treated group, but they were not statistically significant. The activity of NADPH-cytochrome P450 reductase was significantly increased dose dependently(p<0.01), but the activity of NADH-b5 reductase was decreased in the treated group(p<0.01). The activities of PROD and EROD were not significant between control and treated group. The activities of pNPH in the DMF treated groups were higher than that of the control group(p<0.01). When Western immunoblottings were carried out utilizing three monoclonal antibodies which were specific against P4501A1/1, P4502B1/2 and P4502E1, the strong density band corresponding to P4502E1 was observed with the microsomes obtained from the rats treated with DMF. But there were no significant increased in the P4501A1/2 and P4502B1/2 band densities in immunoblotting. Conclusions. These result suggested that P4502E1 was inducible by DMF and P4502E1 isozyme might be responsible for the hydroxylation of DMF to HMMF.

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