• Journal of the Korean Society of Marine Environment & Safety
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• v.28 no.2
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• pp.385-393
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• 2022

Hydrogen has reduced greenhouse gas (GHG) emissions, the main cause of global warming, and is emerging as an eco-friendly energy source for ships. Hydrogen is a substance with a lower flammability limit (LFL) of 4 to 75% and a high risk of explosion. To be used for ships, it must be sufficiently safe against leaks. In this study, we analyzed the effect of changes in the area of the air inlet / vent port on the ventilation performance when hydrogen leaks occur in the hydrogen tank storage room. The area of the air inlet / vent port is 1A = 740 mm × 740 mm, and the size and position can be easily changed on the surface of the storage chamber. Using ANSYS CFX ver 18.1, which is a CFD commercial software, the area of the air inlet / vent port was changed to 1A, 2A, 3A, and 5A, and the hydrogen mole fraction in the storage chamber when the area changed was analyzed. Consequently, the increase in the area of the air inlet port further reduced the concentration of the leaked hydrogen as compared with that of the vent port, and improved the ventilation performance of at least 2A or more from the single air inlet port. As the area of the air inlet port increased, hydrogen was uniformly stratified at the upper part of the storage chamber, but was out of the LFL range. However, simply increasing the area of the vent port inadequately affected the ventilation performance.

• Archives of Plastic Surgery
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• v.49 no.2
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• pp.266-274
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• 2022

Background Many authors have researched ways to optimize fat grafting by looking for a technique that offers safe and long-term fat survival rate. To date, there is no standardized protocol. We designed a "hydraulic system technique" optimizing the relationship among the quantity of injected fat, operative time, and material cost to establish fat volume cutoffs for a single procedure. Methods Thirty-six patients underwent fat grafting surgery and were organized into three groups according to material used: standard, "1-track," and "2-tracks" systems. The amount of harvested and grafted fat as well as material used for each procedure was collected. Operating times were recorded and statistical analysis was performed to establish the relationship with the amount of treated fat. Results In 15 cases the standard system was used (mean treated fat 72 [30-100] mL, mean cost 4.23 ± 0.27 euros), in 11 cases the "1-track" system (mean treated fat 183.3 [120-280] mL, mean cost 7.63 ± 0.6 euros), and in 10 cases the "2-tracks" one (mean treated fat 311[220-550] mL, mean cost 12.47 ± 1 euros). The mean time difference between the standard system and the "1-track" system is statistically significant starting from three fat syringes (90 mL) in 17.66 versus 6.87 minutes. The difference between the "1-track" system and "2-tracks" system becomes statistically significant from 240 mL of fat in 15 minutes ("1-track") versus 9.3 minutes for the "2-tracks" system. Conclusion Data analysis would indicate the use of the standard system, "1-track," and "2-tracks" to treat an amount of fat < 90 mL of fat, 90 ÷ 240 mL of fat, and ≥ 240 mL of fat, respectively.

• Journal of Digital Convergence
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• v.20 no.5
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• pp.653-659
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• 2022

In this study, the awareness of hazardous chemicals and the need for education of dental hygienists were investigated. The subject of this study was an online survey of 103 dental hygienists working in medical institutions from June to August 2021 and analyzed using the SPSS 21.0 program. As a result, work experience was positively correlated with perception (r=.280, p<0.01) and work (r=.303, p<0.01), and work experience with perception (r=.411, p<0.01).Hazardous chemical information showed a positive correlation with practice (r=.371, p<0.01). As a result of the education requirement survey, only 27.2% had experience in hazardous chemical education, and 96.1% of the awareness of the need for education was highly surveyed. As for the desired method of education, 49.5% of them were online education, and the desired time for education was 1 hour. Therefore, in order to create a safe working environment for dental hygienists and to secure the safety of hazardous chemicals, it was necessary to expand educational opportunities at universities, medical institutions, and maintenance education, and to increase accessibility through online education.

• Biomolecules & Therapeutics
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• v.31 no.3
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• pp.350-358
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• 2023

Hand-foot-and-mouth disease (HFMD) is a viral infectious disease that occurs in children under 5 years of age. Its main causes are coxsackievirus (CV) and enterovirus (EV). Since there are no efficient therapeutics for HFMD, vaccines are effective in preventing the disease. To develop broad coverage against CV and EV, the development of a bivalent vaccine form is needed. The Mongolian gerbil is an efficient and suitable animal model of EV71 C4a and CVA16 infection used to investigate vaccine efficacy following direct immunization. In this study, Mongolian gerbils were immunized with a bivalent inactivated EV71 C4a and inactivated CVA16 vaccine to test their effectiveness against viral infection. Bivalent vaccine immunization resulted in increased Ag-specific IgG antibody production; specifically, EV71 C4a-specific IgG was increased with medium and high doses and CVA16-specific IgG was increased with all doses of immunization. When gene expression of T cell-biased cytokines was analysed, Th1, Th2, and Th17 responses were found to be highly activated in the high-dose immunization group. Moreover, bivalent vaccine immunization mitigated paralytic signs and increased the survival rate following lethal viral challenges. When the viral RNA content was determined from various organs, all three doses of bivalent vaccine immunization were found to significantly decrease viral amplification. Upon histologic examination, EV71 C4a and CVA16 induced tissue damage to the heart and muscle. However, bivalent vaccine immunization alleviated this in a dose-dependent manner. These results suggest that the bivalent inactivated EV71 C4a/CVA16 vaccine could be a safe and effective candidate HFMD vaccine.

• The Korea Journal of Herbology
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• v.24 no.4
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• pp.205-213
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• 2009

Objectives : Cancer incidence is increasing in all countries and chemotherapy-induced peripheral neuropathy (CIPN) in patients undergoing chemotherapeutic agents have been a clinically serious problems. So far therapeutic options for CIPN patients are limited and no confirmed methods have yet been established for dealing with peripheral neuropathy. Therefore this review is to provide an evidence-based summary of oriental medicine and CAM (complementary and alternative medicine) neuroprotective and treatment therapies which have gone through clinical trials. Methods : An overview of the domestic and international papers of adult clinical trials relating management of only CIPN symptoms through 1990 to present were searched by electronic databases. Search key words were chemotherapy-induced neurotoxicity, chemotherapy-induced peripheral neuropathy, chemotherapy toxicity & herb, chemotherapy toxicity & acupuncture, chemotherapy toxicity & CAM. Only English and Korean written papers were reviewed. Total 25 papers were reviewed in this study, 18 papers were retrieved by electronic search. Results : Clinical studies of managing CIPN were rare, two acupuncture clinical studies and four herb medicinal studies were found. Rest of 19 papers were about other CAM clinical studies. Total 25 papers were analyzed, and all interventions were focused on their pain control efficacy. Other 24 trials of potential therapies except one proved to be effective for CIPN, however some described to be inadequate positive or sufficient negative. Conclusions : As most of the studies were pilot studies, interventions for the prevention and treatment of CIPN have to go through prospective confirmatory studies, such as larger scale randomized, double-blinded, placebo controlled clinical trials must be done for the safe and effective use of proposed therapies. Also standard measurement scales have to be developed for the better clinical study of CIPN.

• Clean Technology
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• v.16 no.2
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• pp.88-94
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• 2010

The physiological roles of various wavelength of light emitting diode (LED) on ‘Hayward’ kiwifruit experiencing after-ripening were investigated. Various wavelengths from LED light source were irradiated on kiwifruits kept in plastic bags or under open air at $25^{\circ}C$. During two weeks of storage, firmness of Hayward kiwifruits was decreased by $25^{\circ}C$ treatment than by $4^{\circ}C$ treatment. In the $25^{\circ}C$ storage condition, the firmness of kiwifruits was decreased by the treatment of 380 nm UV and 470nm white LED light source. Sweetness of kiwifruits treated with 380 nm UV LED and dark condition at $25^{\circ}C$ increased higher than $15^{\circ}$Brix. The acidity of kiwifruits under open air was decreased 52% by incubating at $25^{\circ}C$ with 660 nm red LED treatment. The acidity of kiwifruits in plastic bags was decreased 52.6, 55.6, 52.8% by the treatment of 440 nm blue, 470 nm white and 660 nm red LED light source, respectively, compared to that of kiwifruits incubated in darkness at $25^{\circ}C$. Decreased acidity irradiated by 660 nm red LED light source can be applied for regulating periods of the kiwifruit after-ripening process. LED light sources emit very narrow wavelength with a power-saving mode, therefore, the usage of these LED light source for regulating the after-ripening process can be classified as a clean biotechnology producing safe and environment-friendly kiwifruits.

• 한국체육학회지인문사회과학편
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• v.55 no.3
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• pp.43-57
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• 2016

This narrative study aims to describe the experience of P.E. assessment that was conducted by P.E. teachers of Korea Science Academy of KAIST, and interpret the educational significance that was found in the process. The study participants were two P.E. teachers who were selected by decisive case sampling method. Data were collected mainly through official interviews with study participants, and through researcher's field notes, informal interviews, various minutes, students' evaluation of teaching, and emails between the researcher and study participants. Data were analyzed through inductive categorization, and to gain veracity of the study, there were integration of diverse materials, advice and suggestions of fellow researchers, continuous confirmation of study texts by study participants. Study participants, while conducting P.E. assessment in Korea Science Academy of KAIST, experienced effectiveness of evaluation such as qualitative development of P,E. classes in accordance with the simplified assessment, freedom from the chores of handling assessment results, students' improved perceptions of P.E. class, realization of safe classes without excessive competition, and the possibility of giving alternative evaluations to pass/fail system but at the same time experienced limitations such as concerns over gaining validity and reliability of P.E. evaluation, the students' attitude who take lightly of P.E. class, and the reality that teachers cannot fail students. The evaluation experiences of the two P.E teachers were educationally interpreted as encounter with good P.E. classes, invitation to P.E. class criticism, and the start of school P.E. culture that is led by students.

• Journal of the Korea institute for structural maintenance and inspection
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• v.27 no.6
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• pp.182-192
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• 2023

In this study, the efficacy of Engineered Cementitious Composite(ECC) jacket for masonry fences subjected to lateral dynamic load was experimentally verified through a shaking table test, comparing it with the performance of an unreinforced masonry(URM) fence. Firstly, dominant frequencies, modal damping ratios and deformed shapes were identified through an impact hammer test. URM and ECC-strengthened fences with heights of 940mm and 970mm had natural frequencies of 6.4 and 35.3Hz, and first modal damping ratios of 7.0 and 5.3%, respectively. Secondly, a shaking table test was conducted in the out-of-plane direction, applying a historical earthquake, El Centro(1940) scaled from 25 to 300%. For the URM fence, flexural cracking occurred at the interface of brick and mortar joint(i.e., bed joint) at the ground motion scaled to 50%, and out-of-plane overturning failure followed during the subsequent test conducted at the ground motion scaled to 30%. On the other hand, the ECC-jacketed fence showed a robust performance without any crack or damage until the ground motion scaled to 300%. Finally, the base shear forces exerted upon the URM and ECC-jacketed fences by the ground motions scaled to 25~300% were evaluated and compared with the ones calculated according to the design code. In contrast to the collapse risk of the URM fence at the ground motion of 1,000-year return period, the ECC-jacketed fence was estimated to remain safe up to the 4,800-year return period ground motion.

• 대한상한금궤의학회지
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• v.14 no.1
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• pp.1-26
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• 2022

Objectives: We aimed to confirm the safety and effectiveness of the decoction of Sibjo-tang, which is a powder type purgative. In addition, we checked whether the '發作' of 『Shanghanlun』 can be interpreted to have the same meaning as "seizure" in English. By confirming these objectives, we intend to lead the progress in the application of Sibjo-tang and to expand the clinical application of the 152nd provision and Sibjo-tang. Methods: We analyzed the medical records of patients who visited Apgujeongjeongin Oriental Clinic and Almyeon Oriental Clinic for seizures. We confirmed side effects in patients who took Sibjo-tang for a long time. Sibjo-tang was prepared as a hot water extract by using 5 g each of Euphorbiae Pekinensis Radix, Eurphobiae Kansui Radix, and Genkwae Flos and 15 g of Zizyphi Fructus. The "seizure" recorded in the 152nd provision was interpreted through the shape analysis of Oracle bone scripts. The seizure frequency of patients diagnosed with epilepsy after taking Sibjo-tang was compared, and we analyzed other symptoms and psychosocial conditions associated with seizures at the first episode. Results: No side effects were found in 7 patients who took Sibjo-tang for 16.57 ± 14.10 months. Seizures were eliminated in 6 cases while taking Sibjo-tang and significantly decreased in 1 case. Frequent indigestion (in 7 cases), mild exhaustion (in 5 cases), and inferiority complex (in 5 cases) were identified as accompanying pathogenic conditions. The "seizure" in the 152nd provision was interpreted as "a state of being stabbed by a sharp substance in clothes", confirming a deep connection with epileptic seizures. Conclusions: The results suggest that using a decoction of Sibjo-tang is safe and efficacious. In addition, the necessity of conducting an advanced study on epileptic seizures accompanied by frequent indigestion using Sibjo-tang was confirmed.

• Journal of the Korean Society of Radiology
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• v.17 no.5
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• pp.791-800
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• 2023

This study was conducted to lay the foundation for creating a society safe from radiation by investigating the establishment of a radiation social safety net and the establishment of safety awareness and safety culture among citizens living in Busan. Data was collected through an online survey, and 200 copies of the survey were analyzed. Data were analyzed using SPSS Window Ver 28.0. To verify differences between groups, t-test and one way ANOVA were performed, and correlation analysis was performed to confirm the relationship between variables. In addition, multiple linear regression analysis was conducted to confirm the influence between variables. As a result, first, in terms of building a social safety net, citizens' safety awareness, and establishing a safety culture, the scores of the group with male gender, age in 20s, and high school graduation were found to be high. Among them, there was a statistical difference in gender at the significance level of .01 for building a social safety network and at the significance level of .05 for establishing a safety culture. In terms of occupation, there was a statistical difference between professionals and service workers at the significance level of .05 regarding the building of a radiation social safety network. Second, as a result of multiple regression analysis, it was found that 'local government radiation safety education', a subordinate factor in building a radiation social safety network, had a positive effect on citizens' safety awareness and establishment of a safety culture. Third, the results of the correlation analysis between the building of a social safety network, citizens' safety awareness, and establishment of a safety culture showed a positive correlation. Therefore, it is believed that a good radiation social safety network will have a positive impact on citizens' safety awareness and the establishment of a safety culture.