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Interlaboratory Comparison of Blood Lead Determination in Some Occupational Health Laboratories in Korea (일부 산업보건기관들의 혈중연 분석치 비교)

  • Ahn, Kyu Dong;Lee, Byung Kook
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.5 no.1
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    • pp.8-15
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    • 1995
  • The reliable measurement of metal in biological media in human body is one of critical indicators for the proper evaluation of its toxic effect on human health. Recently in Korea the necessity of quality assurance of measurement in occupational health and occupational hygiene fields brought out regulatory quality control program. Lead is often used as a standard metal for the program in both fields of occupational health and hygiene. During last 20 years lead poisoning was prevalent in Korea and still is one of main heavy metal poisoning and the capability of the measurement of blood lead is one of prerequisites for institute of specialized occupational health in Korea. Furthermore blood lead is most important indicator to evaluate lead burden of human exposure to lead and the reliable and accurate analysis is most needed whenever possible. To evaluate the extent of the interlaboratory differences of blood lead measurement in several well-known institute specialized in occupational health in Korea, authors prepared 68 blood samples from two storage battery industries and all samples were divided into samples with 2 ml. One set of 68 samples were analyzed by authors's laboratory(Soonchunhyang University Institute of Industrial Medicine: SIIM) and 40 samples of other set were analyzed by C University Institute of Industrial Medicine(CIIM) and the rest 28 samples of other set were analyzed by Japanese institute(K Occupational Health Center:KOHC). Authors also prepared test bovine samples which were obtained from Japanese Federation of Occupational Health Organization (JFOHO) for quality control. Authors selected 2 other well-known occupational health laboratories and one laboratory specialized for instrumental analysis. A total of 6 laboratories joined the interlaboratory comparison of blood lead measurement and the results obtained were as follows: 1. There was no significant difference in average blood lead between SIIM and CIIM in different group of blood lead concentration, and the relative standard deviation of two laboratories was less than 3.0%. On the other hand, there was also no significant difference of average blood lead between SIIM and KOHC with relative standard deviation of 6.84% as maximum. 2. Taking less than 15% difference of mean or less than 6 ug/dl difference in below 40 ug/dl in whole blood as a criteria of agreement of measurement between two laboratories, agreement rates were 87.5%(35/40) and 78.6%(22/28) between SIIM and CIIM, SIIM and KOHC respectively. 3. The correlation of blood lead between SIIM and CIIM was 0.975 (p=0.0001) and the regression equation was SIIM = 2.19 + 0.9243 ClIM, whereas the correlation between SUM and KOHC was O.965(p=0.0001) with the equation of SIIM = 1.91 + 0.9794 KOHC. 4. Taking the reference value as a dependent variable and each of 6 laboratories's measurement value as a independent variable, the determination coefficient($R^2$) of simple regression equations of blood lead measurement for bovine test samples were very high($R^2>0.99$), and the regression coefficient(${\beta}$) was between 0.972 and 1.15 which indicated fairly good agreement of measurement results.

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Modeling of Estimating Soil Moisture, Evapotranspiration and Yield of Chinese Cabbages from Meteorological Data at Different Growth Stages (기상자료(氣象資料)에 의(依)한 배추 생육시기별(生育時期別) 토양수분(土壤水分), 증발산량(蒸發散量) 및 수량(收量)의 추정모형(推定模型))

  • Im, Jeong-Nam;Yoo, Soon-Ho
    • Korean Journal of Soil Science and Fertilizer
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    • v.21 no.4
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    • pp.386-408
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    • 1988
  • A study was conducted to develop a model for estimating evapotranspiration and yield of Chinese cabbages from meteorological factors from 1981 to 1986 in Suweon, Korea. Lysimeters with water table maintained at 50cm depth were used to measure the potential evapotranspiration and the maximum evapotranspiration in situ. The actual evapotranspiration and the yield were measured in the field plots irrigated with different soil moisture regimes of -0.2, -0.5, and -1.0 bars, respectively. The soil water content throughout the profile was monitored by a neutron moisture depth gauge and the soil water potentials were measured using gypsum block and tensiometer. The fresh weight of Chinese cabbages at harvest was measured as yield. The data collected in situ were analyzed to obtain parameters related to modeling. The results were summarized as followings: 1. The 5-year mean of potential evapotranspiration (PET) gradually increased from 2.38 mm/day in early April to 3.98 mm/day in mid-June, and thereafter, decreased to 1.06 mm/day in mid-November. The estimated PET by Penman, Radiation or Blanney-Criddle methods were overestimated in comparison with the measured PET, while those by Pan-evaporation method were underestimated. The correlation between the estimated and the measured PET, however, showed high significance except for July and August by Blanney-Criddle method, which implied that the coefficients should be adjusted to the Korean conditions. 2. The meteorological factors which showed hgih correlation with the measured PET were temperature, vapour pressure deficit, sunshine hours, solar radiation and pan-evaporation. Several multiple regression equations using meteorological factors were formulated to estimate PET. The equation with pan-evaporation (Eo) was the simplest but highly accurate. PET = 0.712 + 0.705Eo 3. The crop coefficient of Chinese cabbages (Kc), the ratio of the maximum evapotranspiration (ETm) to PET, ranged from 0.5 to 0.7 at early growth stage and from 0.9 to 1.2 at mid and late growth stages. The regression equation with respect to the growth progress degree (G), ranging from 0.0 at transplanting day to 1.0 at the harvesting day, were: $$Kc=0.598+0.959G-0.501G^2$$ for spring cabbages $$Kc=0.402+1.887G-1.432G^2$$ for autumn cabbages 4. The soil factor (Kf), the ratio of the actual evapotranspiration to the maximum evapotranspiration, showed 1.0 when the available soil water fraction (f) was higher than a threshold value (fp) and decreased linearly with decreasing f below fp. The relationships were: Kf=1.0 for $$f{\geq}fp$$ Kf=a+bf for f$$I{\leq}Esm$$ Es = Esm for I > Esm 6. The model for estimating actual evapotranspiration (ETa) was based on the water balance neglecting capillary rise as: ETa=PET. Kc. Kf+Es 7. The model for estimating relative yield (Y/Ym) was selected among the regression equations with the measured ETa as: Y/Ym=a+bln(ETa) The coefficients and b were 0.07 and 0.73 for spring Chinese cabbages and 0.37 and 0.66 for autumn Chinese cabbages, respectively. 8. The estimated ETa and Y/Ym were compared with the measured values to verify the model established above. The estimated ETa showed disparities within 0.29mm/day for spring Chinese cabbages and 0.19mm/day for autumn Chinese cabbages. The average deviation of the estimated relative yield were 0.14 and 0.09, respectively. 9. The deviations between the estimated values by the model and the actual values obtained from three cropping field experiments after the completion of the model calibration were within reasonable confidence range. Therefore, this model was validated to be used in practical purpose.

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Analytical Method of Partial Standing Wave-Induced Seabed Response in Finite Soil Thickness under Arbitrary Reflection (임의반사율의 부분중복파동장에서 유한두께를 갖는 해저지반 내 지반응답의 해석법)

  • Lee, Kwang-Ho;Kim, Do-Sam;Kim, Kyu-Han;Kim, Dong-Wook;Shin, Bum-Shick
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.26 no.5
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    • pp.300-313
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    • 2014
  • Most analytical solutions for wave-induced soil response have been mainly developed to investigate the influence of the progressive and standing waves on the seabed response in an infinite seabed. This paper presents a new analytical solution to the governing equations considering the wave-induced soil response for the partial standing wave fields with arbitrary reflectivity in a porous seabed of finite thickness, using the effective stress based on Biot's theory (Biot, 1941) and elastic foundation coupled with linear wave theory. The newly developed solution for wave-seabed interaction in seabed of finite depth has wide applicability as an analytical solutions because it can be easily extended to the previous analytical solutions by varying water depth and reflection ratio. For more realistic wave field, the partial standing waves caused by the breakwaters with arbitrary reflectivity are considered. The analytical solutions was verified by comparing with the previous results for a seabed of infinite thickness under the two-dimensional progressive and standing wave fields derived by Yamamoto et al.(1978) and Tsai & Lee(1994). Based on the analytical solutions derived in this study, the influence of water depth and wave period on the characteristics of the seabed response for the progressive, standing and partial standing wave fields in a seabed of finite thickness were carefully examined. The analytical solution shows that the soil response (including pore pressure, shear stress, horizontal and vertical effective stresses) for a seabed of finite thickness is quite different in an infinite seabed. In particular, this study also found that the wave-induced seabed response under the partial wave conditions was reduced compared with the standing wave fields, and depends on the reflection coefficient.

Chemical Factors of Soil Associated with the Prediction Model for Fertilizer Need of N and K in Flooded Rice based on the Multinutrient Factor Balance Concept (다요인조절개념하(多要因調節槪念下)에서의 수도(水稻) N. K 시비적량여측(施肥適量予測) 모형식(模型式)에 관여(關與)하는 토양화학적(土壤化學的) 요인(要因))

  • Park, Chon-Suh
    • Korean Journal of Soil Science and Fertilizer
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    • v.16 no.3
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    • pp.210-222
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    • 1983
  • The chemical factors of topsoil, which are associated with the prediction models of urea nitrogen (N kg/ha) need under the concept of multinutrient factor balance in soil to maintain optimum nutrient balance in rice plant grown in flooded condition, were the x/z and the Kas/Kai values. In the prediction model or equation $NRe=(58.5+0.647x/z){\cdot}F$, the F was difined as the productivity factor, which was considered to be dependent on the variety, climate and soil, and found to be better estimated as the function of Kas/Kai rather than x/z from the equation Fb=0.65+1.086kas/kai, where the x, z, Kas and Kai, respectively, were available $SiO_2$ ppm, % organic matter, K activity ratio or exchangeable $K^+/(\sqrt{Ca+Mg}+Na^+)$ in topsoil and the ideal K activity ratio determined by the equation Kai=0.03+0.00083x/z for standard variety Jinheung. The relative K activity ratio or Kas/kai in topsoil, which have to be equal to 1.0 in the prediction of K fertilizer need for standard Japonica Variety Jinheung, found to be 1.63 for the varieties of Indica ${\times}$ Japonica or Milyang No. 23 grown in Korean condition and 0.322 for the Indica varieties of IR 8, 20, 36 and 42 gown in the Philippines condition. The ideal K activity rations for different Varieties such as Indies ${\times}$ Japonica grown in Korea or $Kai_1$ and Indica grown in the Philippines or $Kai_2$ were computed to be estimated from the following equations respectively ; $\\Kai_1=0.0489+0.001353X/Z\\Kai_2=0.01+0.000267X/Z$.

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Study of new adsorption isotherm model and kinetics of dissolved organic carbon in synthetic wastewater by granular activated carbon (입상활성탄에 의한 합성폐수의 용존유기물질의 새로운 흡착등온 모델 및 운동학적 흡착 연구)

  • Kim, Seoung-Hyun;Shin, Sunghoon;Kim, Jinhyuk;Woo, Dalsik;Lee, Hosun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.4
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    • pp.2029-2035
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    • 2014
  • In this study, we conducted the adsorption equilibrium and batch experiments of dissolved organic carbon (DOC) in the wastewater by granular activated carbon (GAC). The components of organic compound were Beef extract (1.8 mg/L), Peptone (2.7 mg/L), Humic acid (4.2 mg/L), Tannic acid (4.2 mg/L), Sodium lignin sulfonate (2.4 mg/L), Sodium lauryle sulfate (0.94 mg/L), Arabic gum powder (4.7 mg/L), Arabic acid (polysaccharide) (5.0 mg/L), $(NH_4)_2SO_4$ (7.1 mg/L), $K_2HPO_4$ (7.0 mg/L), $NH_4HCO_3$ (19.8 mg/L), $MgSO_4{\cdot}7H_2O$ (0.71 mg/L), The adsorption characteristics of DOC in synthetic wastewater was described using the mathematical model through a series of isotherm and batch experiments. It showed that there was linear adsorption region in the low DOC concentration (0~2.5 mg/L) and favorable adsorption region in high concentration (2.5~6 mg/L). The synthetic wastewater used was prepared using known quantities of organic and/or inorganic compounds. Adsorption modelling isotherms were predicted by the Freundlich, Langmuir, Sips and hybrid isotherm equations. Especially, hybrid isotherm of Linear and Sips equation was a good adsorption equilibrium in the region of the both the low concentration and high concentration. In applying carbon adsorption for treating water and wastewater, hybrid adsorption equation plus linear equation with Sips equation will be a good new adsorption equilibrium model. Linear driving force approximation (LDFA) kinetic equation with Hybrid (linear+Sips) adsorption isotherm model was successfully applied to predict the adsorption kinetics data in various GAC adsorbent amounts.

Estimation of Temporal Surface Air Temperature under Nocturnal Inversion Conditions (야간 역전조건 하의 지표기온 경시변화 추정)

  • Kim, Soo-ock
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.19 no.3
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    • pp.75-85
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    • 2017
  • A method to estimate hourly temperature profiles on calm and clear nights was developed based on temporal changes of inversion height and strength. A meteorological temperature profiler (Model MTP5H, Kipp and Zonen) was installed on the rooftop of the Highland Agriculture Research Institute, located in Daegwallyeong-myeon, Pyeongchang-gun, Gangwon-do. The hourly vertical distribution of air temperature was measured up to 600 m at intervals of 50 m from May 2007 to March 2008. Temperature and relative humidity data loggers (HOBO U23 Pro v2, Onset Computer Corporation, USA) were installed in the Jungdae-ri Valley, located between Gurye-gun, Jeollanam-do and Gwangyang-si, Jeollanam-do. These loggers were used to archive measurements of weather data 1.5 m above the surface from October 3, 2014, to November 23, 2015. The inversion strength was determined using the difference between the temperature at the inversion height, which is the highest temperature in the profile, and the temperature at 100 m from the surface. Empirical equations for the changes of inversion height and strength were derived to express the development of temperature inversion on calm and clear nights. To estimate air temperature near the ground on a slope exposed to crops, the equation's parameters were modified using temperature distribution of the mountain slope obtained from the data loggers. Estimated hourly temperatures using the method were compared with observed temperatures at 19 weather sites located within three watersheds in the southern Jiri-mountain in 2015. The mean error (ME) and root mean square error (RMSE) of the hourly temperatures were $-0.69^{\circ}C$ and $1.61^{\circ}C$, respectively. Hourly temperatures were often underestimated from 2000 to 0100 LST the next day. When temperatures were estimated at 0600 LST using the existing model, ME and RMSE were $-0.86^{\circ}C$ and $1.72^{\circ}C$, respectively. The method proposed in this study resulted in a smaller error, e.g., ME of $-0.12^{\circ}C$ and RMSE of $1.34^{\circ}C$. The method could be improved further taking into account various weather conditions, which could reduce the estimation error.

Economic Rationale of Compensating Balance Requirements and Its Impact on Money Supply (「꺾기」의 경제학(經濟學)과 통화량(通貨量) 효과분석(效果分析))

  • Jwa, Sung-hee
    • KDI Journal of Economic Policy
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    • v.14 no.1
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    • pp.89-119
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    • 1992
  • This paper purports to analyze the economic rationale of compensating balance requirements and its impact on money supply. This practice has recently been severely criticized for artificially increasing the money supply and, therefore, limiting the nation's aggregate lending policy under the tight constraint of the given money supply target. A review of the existing literature implies that compensating balance requirements is a banking practice which leads to corrections in the distortion of financial resource allocation due to the imperfection of financial market stemming from asymmetric information and/or financial regulations on deposit and lending rates. Therefore, the economic rationale of this practice is deemed to improve the efficiency of financial resource allocation. On the other hand, the macroeconomic impact of compensating balance requirements on the money supply depends on the impact on the money multiplier, which in turn depends on the desired ratio of deposit that people wish to maintain on the money borrowed from the banking system, and on the desired reserve ratio that the banking system would like to hold for deposit withdrawal. If the compensating balance requirements could increase the desired ratio of deposit to borrowing (bank lending), it will increase the available amount of total reserve within the banking system and, in turn, the money multiplier. However, this channel has not been fully analyzed in the literature, and the direction of the effect is ambiguous. If the practice could reduce the turn-over rate of deposit and, thereby, reduce the desired reserve ratio of the banking system, then it will also increase the money multiplier. While this channel operates unambiguously toward increasing the money multiplier, this effect will be limited by the extent that the banking system holds the excess reserve over the required reserve because the excess reserve will set the maximum amount for the desired reserve to fall. This paper tries to determine the effect on the money supply by empirically estimating the multiplier and the desired ratio of deposit to lending equations as functions of the ratio of compensating balance to the related lending, which is not observable and is estimated for the regression purpose. The results suggest that the effect of compensating balance requirements on the money supply in Korea does not exist or is very tenuous even if it could operate. Therefore, this paper concludes that the well publicized policy of cross cancelling the compensating balance and the related lending will not be effective at controlling the money supply and increasing the amount of loans without expanding the money supply.

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Normal Predictive Values of Spirometry in Korean Population (한국인의 정상 폐활량 예측치)

  • Choi, Jung Keun;Paek, Domyung;Lee, Jeoung Oh
    • Tuberculosis and Respiratory Diseases
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    • v.58 no.3
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    • pp.230-242
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    • 2005
  • Background : Spirometry should be compared with the normal predictive values obtained from the same population using the same procedures, because different ethnicity and different procedures are known to influence the spirometry results. This study was performed to obtain the normal predictive values of the Forced Vital Capacity(FVC), Forced Expiratory Volume in 1 Second($FEV_1$), Forced Expiratory Volume in 6 Seconds($FEV_6$), and $FEV_1/FVC$ for a representative Korean population. Methods : Based on the 2000 Population Census of the National Statistical Office of Korea, stratified random sampling was carried out to obtain representative samples of the Korean population. This study was performed as a part of the National Health and Nutrition Survey of Korea in 2001. The lung function was measured using the standardized methods and protocols recommended by the American Thoracic Society. Among those 4,816 subjects who had performed spirometry performed, there was a total of 1,212 nonsmokers (206 males and 1,006 females) with no significant history of respiratory diseases and symptoms, with clear chest X-rays, and with no significant exposure to respiratory hazards subjects. Their residence and age distribution was representative of the whole nation. Mixed effect models were examined based on the Akaike's information criteria in statistical analysis, and those variables common to both genders were analyzed by regression analysis to obtain the final equations. Results : The variables affecting the normal predicted values of the FVC and $FEV_6$ for males and females were $age^2$, height, and weight. The variables affecting the normal predicted values of the $FEV_1$ for males and females were $age^2$, and height. The variables affecting the normal predicted values of the $FEV_1/FVC$ for male and female were age and height. Conclusion : The predicted values of the FVC and $FEV_1$ was higher in this study than in other Korean or foreign studies, even though the difference was < 10%. When compared with those predicted values for Caucasian populations, the study results were actually comparable or higher, which might be due to the stricter criteria of the normal population and the systemic quality controls applied to the whole study procedures together with the rapid physical growth of the younger generations in Korea.

Study on Glomerular Filtration Rate comparison according to renal depth measurement of kidney donors (신 공여자에서 신장 깊이 측정에 따른 사구체여과율의 비교에 관한 고찰)

  • Lee, Han Wool;Park, Min Soo;Kang, Chun Goo;Cho, Seok Won;Kim, Joo Yeon;Kwon, O Jun;Lim, Han Sang;Kim, Jae Sam;Park, Hoon-Hee
    • The Korean Journal of Nuclear Medicine Technology
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    • v.18 no.2
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    • pp.48-56
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    • 2014
  • Purpose $^{99m}Tc$-DTPA renal scintigraphy serves as a key indicator to measure a kidney donor's Glomerular Filtration Rate (GFR) and determine the possibility of kidney transplant. The Gates method utilized to measure GFR considers 3 variables of renal depth, injection dose, and net kidney counts. In this research, we seek to compare changes in kidney donors' GFR according to renal depth measurement methods of the 3 variables. Materials and Methods We investigated 32 kidney donors who had visited the hospital from October, 2013 to March, 2014 and received abdominal CT and $^{99m}Tc$-DTPA GFR examination. With the cross-section image of the CT and the lateral image from a gamma camera, we measured the renal depth and compared with renal depth calculation equations-Tonnesen, Taylor, and Itoh methods. Renal depth-specific GFR was calculated by using Xeleris Ver. 2.1220 of GE. Then the results were compared with MDRD (Modification of Diet Renal Disease) GFRs based on serum creatinine level. Results The renal depths measured based on the CT and gamma camera images showed high correlation. Tonessen equation gave the lowest GFR value while the value calculated by using the renal depth of CT image was the highest with a 16.62% gap. MDRD GFR showed no statistically significant difference among values calculated through Taylor, Itoh, CT and gamma camera renal depth application (P>0.05), but exhibited a statistically significant change in the value based on Tonnesen equation (P<0.05). Conclusion This research has found that, in GFR evaluation in kidney donors by utilizing $^{99m}Tc$-DTPA, Tonnesen equation-based Gates method underestimated the value than the MDRD GFR. Therefore, if a MDRD GFR value shows a huge difference from the actual examination value, using an image-based renal depth measurement, instead of Tonnesen equation applied to Gates method, is expected to give an accurate GFR value to kidney donors.

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The Comparison of Existing Synthetic Unit Hydrograph Method in Korea (국내 기존 합성단위도 방법의 비교)

  • Jeong, Seong-Won;Mun, Jang-Won
    • Journal of Korea Water Resources Association
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    • v.34 no.6
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    • pp.659-672
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    • 2001
  • Generally, design flood for a hydraulic structure is estimated using statistical analysis of runoff data. However, due to the lack of runoff data, it is difficult that the statistical method is applied for estimation of design flood. In this case, the synthetic unit hydrograph method is used generally and the models such as NYMO method, Snyder method, SCS method, and HYMO method have been widely used in Korea. In this study, these methods and KICT method, which is developed in year 2000, are compared and analyzed in 10 study areas. Firstly, peak flow and peak time of representative unit hydrograph and synthetic unit hydrograph in study area are compared, and secondly, the shape of unit hydrograph is compared using a root mean square error(RMSE). In Nakayasu method developed in Japan, synthetic unit hydrograph is very different from peak flow, peak time, and the shape of representative unit hydrograph, and KICT method(2000) is superior to others. Also, KICT method(2000) is superior to others in the aspects of using hydrologic and topographical data. Therefore, Nakayasu method is not a proper in hydrological practice. Moreover, it is considered that KICT model is a better method for the estimation of design flood. However, if other model, i.e. SCS method, Nakayasu method, and HYMO method, is used, parameters or regression equations must be adjusted by analysis of real data in Korea.

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