• Journal of Physiology & Pathology in Korean Medicine
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• v.25 no.6
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• pp.1044-1049
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• 2011

The purpose of this study was to study clinical characteristics of patients complained of tremor and to evaluate availability of oriental medical treatment. This observation was made on 36 cases that were hospitalized in the Semyung University Oriental Medicine Hospital and evaluated tremor using clinical rating tremor scale(CRTS). The ratio of patients were essential tremor(50%), parkinson's disease(13.9%), psychogenic tremor(13.9%), physiologic tremor(11.1%), cerebellar tremor(11.1%). CRTS score of essential tremor patients decreased significantly. Physiologic tremor patients's CRTS score were under 15 points. Every patient's scores decreased. Two patients's score decreased to 0 point. Every patient were treated with Bojungikki-tang-gamibang. CRTS scores of psychogenic tremor patients were various.(4~24 points) Two patients's scores decreased to 0 point. The CRTS scores of three cases among four patients with cerebellar tremor were not changed. Changes of CRTS score between oriental medication group and western-oriental combined medication group were statistically significant. Changes of CRTS score between over 15 points group and under 15 points group were statistically significant. Kejigayongolmoryo-tang was one of the most widely used herbal medication, which was diagnosed as ascendant hyperactivity of liver yang.

• Journal of Acupuncture Research
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• v.30 no.5
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• pp.203-209
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• 2013

Objectives : The purpose of this study is to report the clinical effects of Korean medical treatment for Kienb$\ddot{o}$ck's disease. Methods : The patient was treated using acupuncture, electroacupuncture, herbal medicine, pharmacopuncture treatment, and other treatments including moxibustion, physical rehabilitation for 6 weeks. And we evaluated the patient through verbal rating scale(VRS), disability of the arm, shoulder and hand(DASH), range of motion(ROM). Results : After treatment, VRS is changed from 7 to 3, DASH is changed from 37.93 to 20.69. And ROM is changed from $60^{\circ}$ to $70^{\circ}$ in wrist flexion, and from $10^{\circ}$ to $15^{\circ}$ in radial deviation. Conclusion : These results suggest that Korean medical treatment is effective to the patient complaining pain and dysfunction.

• The Journal of Internal Korean Medicine
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• v.44 no.4
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• pp.603-620
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• 2023

Objectives: This study reviewed randomized controlled trials (RCTs) investigating the efficacy of herbal medicine on sleep disorders associated with Parkinson's disease and suggests a better research process. Methods: We searched for RCTs for herbal medicine treatments for sleep disorders related to Parkinson's disease on July 31, 2023 using eight databases (PubMed, Embase, the Cochrane library, China National Knowledge Infrastructure [CNKI], the Research Information Service System [RISS], Science ON, the Oriental Medicine Advanced Searching Integrated System [OASIS], and the Korea Citation Index [KCI]). Cochrane's risk of bias tool was used to assess the quality of the RCTs. Results: A total of 16 RCTs met all the inclusion criteria, and in most reports, the treatment group showed a significant improvement in sleep disorders compared to the control group. Total effective rate (TER), Pittsburgh Sleep Quality Index (PSQI), Unified Parkinson's Disease Rating Scale (UPDRS), TCM Symptom Score (TSS), Parkinson's Disease Sleep Scale (PDSS), etc., were used as evaluation indicators. Conclusion: Herbal medicine is a potential treatment for sleep disorders associated with Parkinson's disease. However, the selected RCTs were of poor quality, and it is necessary to perform more systematic studies.

• The Journal of Internal Korean Medicine
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• v.38 no.2
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• pp.103-109
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• 2017

Objective: To describe the effects of traditional Korean medicine (TKM) on a patient diagnosed with Parkinson's disease. Methods: The patient was treated with Korean medicine, including pharmacopuncture, acupuncture, and Chungpajunsin-bang. The Unified Parkinson's Disease Rating Scale (UPDRS) and modified Hoehn and Yahr staging (H-Y stage) were used to measure changes in amplitude and improvements in the patient's symptoms. Results: After treatment with the Korean medicine, according to the UPDRS and H-Y stage assessments, the patient's tremor improved, with the tremor amplitude decreasing from 30 cm to 5 cm. Conclusions: We suggest that TKM could be effective in reducing tremor in Parkinson's disease.

• The Journal of Internal Korean Medicine
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• v.30 no.4
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• pp.901-908
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• 2009

Parkinson's disease is a slowly progressive degenerative disorder of the central nervous system. It is characterized by tremor when muscles are at rest, increased muscle tone, slowness of voluntary movements, and difficulty maintaining balance. In oriental medicine, these symptoms are diagnosed as yin(陰)-deficiency of liver and kidney, deficiency of qi(氣) and blood, retention of phlegm(痰), qi-stagnation and blood stasis. In this case, we diagnosed patients as deficiency of qi(氣) and blood type according to symptoms and treated by herbs that strengthen yang and benefiting yin for two weeks, while maintaining existing parkinson's western medication. After treatment, clinical symptoms were improved, while UPDRS (Unified Parkinson's Disease Rating Scale) score was decreased. These cases suggest that oriental medicine therapy maybe effective in the treatment of Parkinson's disease.

• The Journal of Internal Korean Medicine
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• v.28 no.4
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• pp.919-928
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• 2007

Objectives : This study was designed to research the effects of oriental treatment on dyskinesia with lower limbs caused by Parkinson's Disease. Methods : We prescribed Yukmijihwang-tang (六味地黃湯) and Jaumganghwa-tang (滋陰降火湯) and treated acupuncture through Shinjungkyuk (腎正格) every day. It was used to treat the Shinjeonghyuson (腎精虧損) symptoms. We analyzed the frequency of dyskinesia over one night at intervals of three days and measured the score of 'Unified Parkinson's Disease Rating Scale' every week to evaluate the entire symptom's improvement. Results and Conclusion : He had been treated with western medicine to improve the dyskinesia symptoms, but couldn't get a noticeable result. Having oriental treatment for 43 days, dyskinesia in the lower limbs mostly disappeared and all symptoms of Parkinson's disease (tremor, rigidity, dysphagia, hallucination, anorexia, etc.) improved significantly.

• Journal of Haehwa Medicine
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• v.19 no.2
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• pp.57-64
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• 2011

Parkinson's disease is a degenerative disease of a cranial nerve and has a main symptoms of irregular movement of muscle, stiffening, trembling which occurred by about 1% of population in the age of over 65. Moreover, the and prevalence rate and attack rate are soaring according to increase of elderly population. However, allopathy and surgery were done through dopamine and anticholinergic medicine for treatment but it developed a lot of complications due to medicine and progress since it makes slow progress or can't stop the treatment. Hereupon, I report that there is a case on one of the patients Young Jin Oriental Medical Clinic. The patient who is in state of treatment termination who doesn't need any further remedy and no worsening of symptoms after conduction of therapies of dialectic and 5 upright life cure regulations. 5 upright life cure regulations means five practive way for improvement of nature healing power. Upon undertaking the 5 upright life cure regulations, there were found significant results in such tests as Unified Parkinson Disease Rating Scale (UPDRS), Hoehn & Yahr Staging Scale, and Activity of Daily Living (ADL), and the ingestion of Benztropine 1mg and Requip 0.25mg was decreased from 3 times to 0 times. The study offers objective clinical data on Oriental Medicine treatment for Parkinson's disease which is one of representative neuro-degenerative diseases and thus broadens the application range of Oriental Medical treatment and presents the fundamental data on the clinical research on Parkinson's disease by adopting evidence-based medicine (EBM).

• Journal of Biomedical Engineering Research
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• v.40 no.5
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• pp.189-196
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• 2019

We investigated differences in ventricular and hippocampal volumes between CSF tap test (CSFTT) responders and non-responders in idiopathic normal-pressure hydrocephalus (INPH) patients and compared these parameters in INPH patients with that of age- and gender-matched healthy controls. We also evaluated relationships between ventricular and hippocampal volumes and clinical profiles in INPH patients. We enrolled 48 patients with INPH and 29 healthy controls. Ventricular and hippocampal volumes were measured on MRI, including 3-dimensional volumetric images. INPH patients, when compared to healthy controls, had significantly larger ventricular and smaller hippocampal volumes. No difference in ventricular and hippocampal volumes was found between CSFTT responders and non-responders in INPH patients. And hippocampal volumes showed significant negative correlations with Clinical Dementia Rating Scale scores, INPH grading scale cognitive scores, Timed Up and Go Test scores, and Unified Parkinson's Disease Rating Scale motor scores in INPH patients. Volumetric assessment of ventricular and hippocampal regions may have no predictive value in differentiating between CSFTT responders and non-responders in INPH patients. Our findings may help us understand the potential pathophysiology of unique symptoms associated with INPH.

• Journal of Korean Medicine Rehabilitation
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• v.28 no.1
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• pp.153-160
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• 2018

The purpose of the study is to explore the possibility of Korean medicine treatment on back pain of Parkinson's disease patient through a case study. A Parkinson's disease patient suffering from back pain and both limbs pain was hospitalized and treated with acupuncture and traditional medicine. We evaluated the treatment effect with Numerial Rate Scale (NRS), Oswestry low back pain disability questionnaire (ODI), EuroQol-Five Dimensions (EQ-5D), and Unified Parkinson's Disease Rating Scale (UPDRS). As a result, back pain NRS, lower limbs pain NRS, ODI, EQ-5D, UPDRS turned out to be greatly improved from 9 to 3, 5 to 2, 80 to 64, -0.014 to 0.513, 122 to 37, respectively. This study suggested that Korean Medicine could be effective treatment for back pain of Parkinson's Disease. Further clinical studies are needed to obtain definite conclusion.

• Annals of Clinical Neurophysiology
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• v.11 no.1
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• pp.9-15
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• 2009

Background: To investigate the differences of locomotor dynamics between Parkinson's disease (PD) patients with tremor dominant symptom and patients with postural instability dominant symptom. Methods: 66 subjects with PD were classified into two subgroups, tremor-dominant group and postural instability and gait disorder group by Unified Parkinson's disease rating scale (UPDRS). The spatial, temporal and electrodynamic gait parameters were recorded automatically using computerized 3-D motion analysis system with electrogoniometer. Results: There was no significant difference in cadence, pelvic tilt range, hip flexion range, knee flexion range and ankle dorsiflexion range. Postural instability and gait disorder group showed decreased gait velocity, short stride length, decreased range of motion in pelvic obliquity, pelvic rotation and ankle plantar flexion. Conclusions: There was meaningful difference in locomotor dynamics between Parkinson's disease(PD) patients with tremor dominant symptom and patients with postural instability dominant symptom.