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Histopathoiogical Findings and Antibody Titers of the Experimental Animals Infected with Aujeszky′s Disease Virus(Korea Isolates) (ADV 국내 분리주를 접종한 실험 동물의 조직 병리 소견과 항체가 연구)

  • 최준식;육동현;김성삼;박석기
    • Korean Journal of Veterinary Service
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    • v.14 no.2
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    • pp.134-142
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    • 1991
  • We surveyed the antibody titers in the slaughtered pigs by enzyme immunodiffusion method for the epidemiological distribution of Aujeszky's disease in Korea. And also we observed the clinical symptoms, histopathological findings and antibody titers by serologic neutralization test in experimental animals infected with Aujeszky's disease virus(ADV) isolated from Korea. The results of the experiments were summarized as follows. 1. We detected 2 pigs infected with ADV of 1000 in 1990 and 1 of 600 in 1991 by enzyme immunodiffusion method. 2. In histopathological findings of experimental animals inoculated ADV, the typical characteristics of Aujeszky's disease were not observed in pig, but edema and degeneration in the epidermis were observed in rats, vasculoendotheriosis, perivascular cuffing and cellular infiltration in the cerebrum were appeared in rabbits and perivascular cuffing and forcal infiltration of glial cells in the cerebrum were appeared in mice. 3. The increasing antibody titers(1 : 64) in the serological neutralization test were ascertained in 2 carrier pigs inoculated ADV. 4. Rabbits, mice and rats died all about 5 days after inoculation, but pigs and chickens didn't die. 5. In 1 cat and 2 rabbits inoculated with the Aujeszky's disease virus(ADV), the typical clinical findings of Aujeszky's disease were observed in rabbit, but not in cat and so we slaughtered without any signs of Aujeszky's disease.

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Recent Clinical Research Trends on Acupuncture Treatment of Meniere's Disease (메니에르 병의 침 치료에 관한 최근 임상 연구 동향)

  • Lee, Kyou-Young;Hong, Chul-Hee
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.31 no.3
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    • pp.26-38
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    • 2018
  • Objectives : The purpose of this study is to investigate the possibility of applying acupuncture to the treatment of meniere's disease, which has no definite treatment methods, by analyzing the latest clinical researches about acupuncture treatment of meniere's disease. Methods : A case study and Randomized Controlled Trial (RCT) related to the acupuncture treatment of meniere's disease were searched using domestic and international thesis search engines including OASIS, CNKI, J-STAGE, PubMed. This study include acupuncture treatment and acupuncture combined with other treatments such as herbal medicine. The search was limitied to the publication date from 2000 to 2018 with free full text. Results : 17 cases were selected. There were 7 case studies in Korea, 5 case studies in China, and 5 RCT papers in China. All 12 cases reported improvement in meniere's disease and all RCT studies showed significantly higher treatment effects in the experimental group than in the control group. Conclusions : Acupuncture treatment showed significant effects for meniere's disease when applied alone or in combination with other treatments. In the future, various systematic studies should be conducted only for acupuncture treatment.

Relationship Between Plantar Foot Pressures and Plantar Ulceration in Patients With Hansen's Disease (한센병 환자의 족저궤양과 최대 족저압력과의 관계)

  • Jung, Do-Young;Park, Kyoung-Hee;Lee, Kang-Sung
    • Physical Therapy Korea
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    • v.9 no.1
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    • pp.63-68
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    • 2002
  • Foot ulceration results in substantial morbidity in patients with peripheral neuropathy. The purpose of this study was to find the relationship of plantar foot pressures during walking to plantar ulceration in patients with Hansen's disease. The subjects were recuruited from two Welfare Clinic for Hansen's disease in Wonju and Uiwang city. Ten subjects (5 females, 5 males) with plantar ulceration and a mean age of 63 years were evaluated in this study. The mean duration of Hansen's disease in these subjects was 30 years. Plantar pressures were measured during self-selected comfortable walking speed by using MatScan system. Three subjects had plantar ulceration under the first metatarsal head. Five subjects had plantar ulceration under the second and third metatarsal head. Two subjects had plantar ulcers under the fifth metatarsal head. Eight of 10 subjects had plantar ulceration at highest pressure point that measured during walking. This result suggests that the abnormal high plantar pressure could be related factor to plantar ulceration in patients with Hansen's disease. Also the foot pressure measurement may be useful to evaluate the risk of plantar ulceration in patients with Hansen's disease.

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Rapid Atypical Progression of Neuro-Behçet's Disease Involving Whole Brainstem and Bilateral Thalami

  • Lee, Sang-Kook;Choi, Sung-Jae;Kim, Sang-Dae;Lim, Dong-Jun
    • Journal of Korean Neurosurgical Society
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    • v.50 no.1
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    • pp.68-71
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    • 2011
  • We present a case of Neuro-Behçet's disease with an unpredictable clinical course. A 47-year-old man was admitted to the neurosurgery department of our hospital with a mild headache. Three days after admission, his consciousness suddenly decreased and respiratory distress progressed rapidly. A brain MRI revealed that the previously observed abnormal signal had extended markedly to both the thalamic areas and the entire brain stem, and the surrounding brain parenchyma were compressed by cerebral edema. Based on the patient's symptoms of recurrent oral and genital ulcers, skin lesions, and uveitis, a rheumatologist made a diagnosis of Behçet's disease with CNS involvement. The patient was treated with high-dose methylprednisolone with respiratory assistance in the intensive care unit for 9 days and his neurologic symptoms improved remarkably. Neuro-Behçet's disease must be considered in the differential diagnosis in rapidly deteriorated young neurological patients along with a stroke, low-grade glioma, multiple sclerosis, and occlusive venous disease.

Validating the Berg Balance Test for Patients with Parkinson's Disease (파킨슨병 환자에서 낙상군과 비낙상군에 대한 버그균형검사의 타당도)

  • Cho, Gyu-Hang;Woo, Young-Keun;Hwang, Su-Jin
    • PNF and Movement
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    • v.9 no.3
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    • pp.31-39
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    • 2011
  • Purpose : The purpose of this study was to evaluate the criterion-related validity of the Berg balance test between fallers and non-fallers in individuals with Parkinson's disease. Methods : Thirty-one patients were recruited for this study. Their initial diagnosis had been made on average $30.1{\pm}10.1$ years earlier. Score of Berg balance test showed significant correlations with indicators of motor functioning and daily living capacity. Berg balance test score was inversely associated with the unified Parkinson's disease rating scale-motor score, and Schwab and England activities of daily living rating scale. Results : In all 3 correlations, lower scores on the Berg balance test correlated with higher unified Parkinson's disease rating scale-motor scores. Results support the criterion-related validity of the Berg balance test. Conclusion : Our research results agree with other published research in suggesting that the Berg balance test may be used as a screening tool and ongoing assessment tool for patients with Parkinson's disease.

Behcet's Disease with the Left Carotid Artery Aneurysm and Colon Perforation (좌측 경동맥류와 대장천공을 동반한 베체트병)

  • 전준경;장원채;최용선;오봉석
    • Journal of Chest Surgery
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    • v.37 no.3
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    • pp.279-281
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    • 2004
  • Behest's disease is manifested as ulcers present in oral cavity, on external genital organ, orbital area, and skin. This disease could also cause other symptoms by invading the cardiovascular system, respiratory system, gastrointestinal system, central nervous system, and urogenital system. It is very rare for Behcet's disease to be accompanied by carotid artery aneurysm and intestinal perforation. We report a patient with Behcet's disease, who is diagnosed with symptoms and pathological findings as haying carotid artery aneurysm and intestinal perforation at the same time. The patient underwent operation for the aneurysm and the intestinal perforation.

Stellate Ganglion Block for Postoperative Recurred Meniere's Disease -A case report- (수술 후 재발된 메니에르병 환자에서의 성상신경절 차단술 -증례 보고-)

  • So, Keum-Young;Kim, Kil-Beom
    • The Korean Journal of Pain
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    • v.12 no.2
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    • pp.235-237
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    • 1999
  • Meniere's disease is a disorder of the membranous labyrinth that is characterized by vertigo, hearing loss, tinnitus and ear fullness. The etiology of Meniere's disease is yet to be described and the management is also very difficult. Fifty-one years old female patient had paroxysm of severe tinnitus and dizziness after medical therapy and surgical intervention during several years. Patient received stellate ganglion block (SGB) and her symptoms were completely relieved. Therefore, SGB could be considered another therapeutic modality for Meniere's disease.

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Emergency Quadrido-Bentall Procedure for Aortic Rupture in a Patient with Behcet's Disease

  • Park, Sung Jun;Lee, Jeong-woo;Kim, Joon Bum
    • Journal of Chest Surgery
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    • v.48 no.5
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    • pp.364-367
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    • 2015
  • Cardiovascular involvement in cases of Behcet's disease is a rare but life-threatening condition, and prosthetic valve detachment is a frequent and serious complication attributable to Behcet's disease following the surgical repair of aortic regurgitation. We report the case of a patient with Behcet's disease presenting with contained aortic rupture around the aortic root. The patient had previously undergone aortic valve surgery three times due to recurrent prosthetic valve detachment. An emergency operation was performed, consisting of aortic root replacement (ARR) using a composite valved conduit and the replacement of the hemiarch. ARR may be an appropriate surgical option for patients with Behcet's disease in order to prevent recurrence of the disease.

Clinical Application of $^{18}F-FDG$ PET in Parkinson's Disease (파킨슨병에서 $^{18}F-FDG$ PET의 임상이용)

  • Lee, Won-Hyoung;Chung, Yong-An
    • Nuclear Medicine and Molecular Imaging
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    • v.42 no.sup1
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    • pp.177-180
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    • 2008
  • Parkinson's disease is the second most common neurodegenerative disorder. It is slowly progressive disease that affects a small area of cells in the mid brain known as the substantia nigra. Gradual degeneration of these cells causes a reduction in a vital chemical known as dopamine. In the diagnosis of Parkinson's disease, it has difficulty in biopsy and limits in radiologic modalities. $^{18}F-FDG$ PET shows various findings from normal to diffuse decrement of FDG uptake. $^{18}F-FDG$ PET is expected to be a evaluation tool in the treatment of Parkinson's disease.

The Castlemen's Disease in Mediastinum -A Case Report- (종격동에 발생한 Castlement's Disease -1례보고-)

  • Yoon, Hoo-Sik;Chang, Gie-Kyung;Kang, Jeong-Soo;Kim, Hun
    • Journal of Chest Surgery
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    • v.33 no.3
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    • pp.265-267
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    • 2000
  • Castleman's disease is a relatively rate disorder of lymphoid tissue and poorly understood etiology. The disease may occur anywhere along the lymphatic chain, but is most commonly found as a solitary mass in the mediastinum. The hyaline vascular type represents 91% of Castlemen's disease, and these are most often discovered in the asymptomatic patient on routine chest film. Patients with the plasma cell type often exhibit systemic symptoms, including fever, night sweats, anemia, and hypergammaglobulinemia. Surgical excision effects cure, although resection of the hyaline vascular type may be associated with significant hemprrage owing to extreme vascularity. We recently experienced a case of hyaline vascular type Castleman's disease which was treated by surgical resection through the anterior mini-thoracotomy, and report with its review.

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