Clinical Application of $^{18}F-FDG$ PET in Parkinson's Disease

파킨슨병에서 $^{18}F-FDG$ PET의 임상이용

  • Lee, Won-Hyoung (Department of Radiology, College of Medicine, The Catholic University of Korea) ;
  • Chung, Yong-An (Department of Radiology, College of Medicine, The Catholic University of Korea)
  • 이원형 (가톨릭대학교 의과대학 방사선과학교실) ;
  • 정용안 (가톨릭대학교 의과대학 방사선과학교실)
  • Published : 2008.12.31

Abstract

Parkinson's disease is the second most common neurodegenerative disorder. It is slowly progressive disease that affects a small area of cells in the mid brain known as the substantia nigra. Gradual degeneration of these cells causes a reduction in a vital chemical known as dopamine. In the diagnosis of Parkinson's disease, it has difficulty in biopsy and limits in radiologic modalities. $^{18}F-FDG$ PET shows various findings from normal to diffuse decrement of FDG uptake. $^{18}F-FDG$ PET is expected to be a evaluation tool in the treatment of Parkinson's disease.

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