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Gastroesophageal Reflux Disease in Infants, Children and Adolescents (소아청소년의 위식도역류)

  • Park, Jae Ock
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.11 no.sup1
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    • pp.55-71
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    • 2008
  • Gastroesophageal reflux (GER) defined as passage of gastric contents into the esophagus without symptoms is a common physiologic gastrointestinal problem in infants, children and even in adults. But gastroesophageal reflux disease (GERD) defined as symptoms or complications of GER is a disease entity to find out the reason and treat. After the era of 1970 we have been studying about GERD with the development of diagnostic and therapeutic methods. I already introduced the nature and the fundamental knowledge of GERD in the opening symposium of KSPGHAN in 1998. Now, I will introduce the guidelines for evaluation and treatment of GERD which was recommended by the North American Society for Pediatric Gastroenterology and Nutrition and American Pediatric Association which was published in 2001. And I will introduce progressing subjects and the forecoming issues to be solved in near future. Those are as followings. Does GERD cause otolaryngologic symptoms such as chronic sinusitis and chronic otitis? Is GERD inherited? Can we find out the child who will become GERD in adult life and the way to reduce the incidence of Barrett's esophagus and esophageal cancer? Is long term PPI therapy safe in children?

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Protection Against Salmonella Typhimurium, Salmonella Gallinarum, and Salmonella Enteritidis Infection in Layer Chickens Conferred by a Live Attenuated Salmonella Typhimurium Strain

  • Lee, John Hwa
    • IMMUNE NETWORK
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    • v.15 no.1
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    • pp.27-36
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    • 2015
  • In the present study, we investigated the protection conferred by a live attenuated Salmonella enterica serovar Typhimurium (ST) strain against Salmonella Typhimurium, Salmonella Gallinarum (SG), and Salmonella Enteritidis (SE) infection in layer chickens. Birds were orally primed with the attenuated ST strain at 7 days of age and then boosted at 4 weeks post prime immunization (PPI). Sequential monitoring of plasma IgG and mucosal secretory IgA (sIgA) levels revealed that inoculation with ST induced a significant antibody response to antigens against ST, SE, and SG. Moreover, significant lymphoproliferative responses to the 3 Salmonella serovars were observed in the immunized group. We also investigated protection against virulent ST, SE, and SG strain challenge. Upon virulent SG challenge, the immunized group showed significantly reduced mortality compared to the non-immunized group. The reduced persistence of the virulent ST and SE challenge strains in the liver, spleen, and cecal tissues of the immunized group suggests that immunization with the attenuated ST strain may not only protect against ST infection but can also confer cross protection against SE and SG infection.

A Study on the Radar Image Generation Method for Ship Handling Simulator

  • Jung, Min;Lee, Sin-Geol;Song, Chae-Uk
    • Journal of Navigation and Port Research
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    • v.30 no.7
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    • pp.611-615
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    • 2006
  • This paper proposes a method for generating radar images used in a ship handling simulator, which includes mathematical logics based on radar equations and information from Openflight format files. In order to make radar image much similar to that of real radar in PPI type, the proposed mathematical logic derives radar video signals under the consideration of not only the data form flight format file of simulation scenes, but also geographical radar's position. The proposed method is considered useful to make radar images in ship handling simulator with accuracy and reality.

Compressive Properties of Open Cell 6063 Aluminium Foam (개포형 6063 발포 알루미늄의 압축특성)

  • Bu, Sung-Duk;Kang, Bok-Hyun;Kim, Ki-Young
    • Journal of Korea Foundry Society
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    • v.27 no.1
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    • pp.36-41
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    • 2007
  • Compressive properties of the open cell 6063 aluminum alloy foams made by the plaster molding process were investigated before and after heat treatment. Loading process was controlled at a displacement rate of 2 mm/min. Compressive strength of 10 PPI foam was the largest of the same density foams. Increase in strength after heat treatment for the bulk material was remark able, however was not for the 6063 aluminum foam. C values were in the range of $0.39{\sim}0.53$ for as cast foams and $0.13{\sim}0.16$ for T6 heat treated foams in the equation of ${sigma}^*_{pl}/{\sigma}_{ys}=C({\rho}/{\rho}_{s})^{1.5}$ and increased with cell size.

A Study on the Radar Image Generation Method in Ship Handling Simulator

  • Jung Min;Lee Sin-Geol;Song Chea-Uk
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
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    • 2006.06b
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    • pp.61-66
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    • 2006
  • This paper proposes a method for generating radar images used in ship handling simulator, which includes mathematical logics based on radar equations and information from Openflight format files. In order to make radar image much similar to that of real radar in PPI type, the proposed mathematical logic derives radar video signals under the consideration of riot only the data form flight format file of simulation scenes, but also geographical radar's position. The proposed method is considered useful to make radar images in ship handling simulator with accuracy and reality.

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Simulation for Signaling Pathway of MAPK Hypotonic Shock (MAPK Hypotonic Shock의 Signaling Pathway에 대한 시뮬레이션)

  • Jo, Mi-Kyung;Seo, Jeong-Man;Park, Hyun-Seok
    • Journal of the Korea Society of Computer and Information
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    • v.14 no.5
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    • pp.175-182
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    • 2009
  • We extracted protein signal delivery path from protein interaction data, using location information and weight of protein. We obtained the protein interaction data by experimenting in two-hybrid system using Yeast. We simulated function's data of Hypotonic Shock comparing to signal delivery path provided in KEGG from the results. We measured process running period as well. In future, this research can be key to discover the origin of various genetic diseases and develop treatment.

A Study on the Construction of Fisheries Producer Price Index (수산물 생산자물가지수 산정방식에 관한 고찰;-연근해 어획물을 중심으로-)

  • 이광진
    • The Journal of Fisheries Business Administration
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    • v.27 no.1
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    • pp.67-90
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    • 1996
  • As an important factor of capitalism economics, price of commodities represents a certain country's economic index. For having correct price policy, there should be an appropriate mechanism to make and use systematic statistical data on price. Price statistics are made by indexes and price indexes are categorized into producer price index(PPI) and consumer price index(CPI). The Bank of Korea is publishing producer price index every year, but the producer price index contains some problems. These include as follows : (a) the impractical selection of fisheries products sample (b) uncorrect measure of aquatic products weights (c) investigating sample places. This study try to substitute producer price index of aquatic products and change construction of fisheries producer price index with experimental research on representative fisheries, weight of each fisheries, and suitability of investigating sample places. It is possible to improve practical fisheries producer price index with the results of this research. The findings are as follow. (a) It will be helpful for the government to make the fisheries price policy. (b) It can be used to understand trends of accurate price and price increase of aquatic products, and it's possible to compare with it other industrial indexes including the mining, agricultural, and manufacturing industry and understand relative price movement. (c) When free sales systems of fisheries products as expected, it will be helpful to analyze price movement of producing fisheries cooperatives, producing fisheries market and consuming fisheries market, analysis of market, and formation and consideration of budget. (d) It can be an important index to determine labor wage.

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Pharmacological Treatment for Peptic Ulcer Bleeding (소화성 궤양 출혈의 약물 치료)

  • Ma, Dae Won;Kim, Byung-Wook
    • The Korean journal of helicobacter and upper gastrointestinal research
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    • v.18 no.4
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    • pp.231-234
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    • 2018
  • Peptic ulcer bleeding (PUB) is the most common cause of non-variceal upper gastrointestinal bleeding, and its frequency has been declining over the past decades. However, mortality from PUB persists, and it is still a serious challenge in clinical practice. Although endoscopic intervention is the basic treatment modality for PUB, pharmacological therapy is an important adjunct. The emergence of proton pump inhibitors (PPIs) enables maintenance of intragastric pH >6, which greatly helps in the treatment of PUB. Continuous intravenous infusion of high-dose PPI reduces the re-bleeding rate, thereby helping avoid additional surgery in patients with high-risk stigmata. Moreover, administration of PPIs prior to endoscopy may reduce the need for additional endoscopic intervention. Recently introduced gastric acid suppressants, such as potassium-competitive acid blockers, have shown promising results in further treatment of PUB.

High performance Algorithm for extracting and redicting MAP Kinase signaling pathways based on S. cerevisiae rotein-Protein Interaction and Protein location Information (S. cerevisiae 단백질간 상호작용과 세포 내 위치 정보를 활용한 MAP Kinase 신호전달경로추출 및 예측을 위한 고성능 알고리즘 연구)

  • Jo, Mi-Kyung;Kim, Min-Kyung;Park, Hyun-Seok
    • Journal of the Korea Society of Computer and Information
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    • v.14 no.3
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    • pp.193-207
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    • 2009
  • Intracellular signal transduction is achieved by protein-protein interaction. In this paper, we suggest high performance algorithm based on Yeast protein-protein interaction and protein location information. We compare if pathways predicted with high valued weights indicate similar tendency with pathways provided in KEGG. Furthermore, we suggest extracted results, which can imply a discovery of new signaling pathways that is yet proven through experiments. This will be a good basis for research to discover new protein signaling pathways and unknown functions of established proteins.

Novel Pyridinium Iodide Containing Siloxane High Performance Electrolyte for Dye-Sensitized Solar Cell

  • Lee, Soonho;Jeon, Youngtae;Lim, Youngdon;Cho, Younggil;Lee, Sangyoung;Kim, Whangi
    • Bulletin of the Korean Chemical Society
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    • v.34 no.9
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    • pp.2583-2588
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    • 2013
  • A new type of solid and gel-state ionics based on siloxane pyridinium iodides was synthesized and used as electrolytes in dye-sensitized solar cells. The resulting electrolytes were characterized by $^1H$ NMR spectroscopy, TGA and diffusion coefficient. The synthesized siloxane pyridinium iodide electrolytes have characteristics of different chain length of siloxane moieties. The ion conductivities were given 2.7-3.2 S/cm. Among the three SiDPIs based electrolytes, DSSC employing the SiDPI2 gives an open circuit voltage of 0.704 V, a short-circuit current of 15.85 $mA/cm^2$ and conversion efficiency of 6.8% under light intensity of 100 $mW/cm^2$. In addition, the performance of the DSSCs showed relatively reasonable compared with the propylpyridinium iodide (PPI) electrolyte.