• Title/Summary/Keyword: role structure

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NMR Studies on the N-terminal Acetylation Domain of Histone H4

  • Bang, Eun Jeong;Lee, Chang Hun;Yun, Jong Bok;Cheong, Ju Hui;Lee, Dae Yun;Lee, Won Tae
    • Bulletin of the Korean Chemical Society
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    • v.22 no.5
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    • pp.507-513
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    • 2001
  • Histones, nuclear proteins that interact with DNA to form nucleosomes, are essential for both the regulation of transcription and the packaging of DNA within chromosomes. The N-terminal domain of histone H4 which contains four acetylation sites at lysines, may play a separate role in chromatin structure from the remainder of the H4 chain. NMR data suggest that H4NTP peptide does have relating disordered structure at physiological pH, however, it has a defined structure at lower pH conditions. The solution structure calculated from NMR data shows a well structured region comprising residues of Val21-Asp24. In addition, our results suggest that the H4NTP prefers an extended backbone conformation at acetylation sites, however, it (especially Lys 12 ) became more defined structures after acetylation for its optimum function.

Interplay between epigenome and 3D chromatin structure

  • Man-Hyuk Han;Dariya Issagulova;Minhee Park
    • BMB Reports
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    • v.56 no.12
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    • pp.633-644
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    • 2023
  • Epigenetic mechanisms, primarily mediated through histone and DNA modifications, play a pivotal role in orchestrating the functional identity of a cell and its response to environmental cues. Similarly, the spatial arrangement of chromatin within the three-dimensional (3D) nucleus has been recognized as a significant factor influencing genomic function. Investigating the relationship between epigenetic regulation and 3D chromatin structure has revealed correlation and causality between these processes, from the global alignment of average chromatin structure with chromatin marks to the nuanced correlations at smaller scales. This review aims to dissect the biological significance and the interplay between the epigenome and 3D chromatin structure, while also exploring the underlying molecular mechanisms. By synthesizing insights from both experimental and modeling perspectives, we seek to provide a comprehensive understanding of cellular functions.

A study on improving the surface structure of solar cell and increasing the light absorbing efficiency - Applying the structure of leaves' surface - (태양전지 텍스처 표면구조 개선 및 빛 흡수효율 향상에 관한 연구 - 식물 잎의 표면구조 적용 -)

  • Kim, Taemin;Hong, Joopyo
    • 한국신재생에너지학회:학술대회논문집
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    • 2010.11a
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    • pp.38.2-38.2
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    • 2010
  • Biomimetc is a new domain of learning that proposes a solution getting clues from nature. There seems to be a sign of this phenomenon in fields of Renewable Energy. Foe example, Wind power was imitate the whale's fin that was improve efficiency of generating energy. This study focused on the photovoltaic generation as the instance of applying biomimetic. Efficiency is the most important factor in field of Photovoltaic generation. When given solar cell taking the sun light, most important fields of the study are absorb more light and increase the quantity of generation. For improving efficiency, the solar cell were builded up textures of taking a pyramid form, such a surface structure taking a role for remaining the light. This effects do the role as increasing absorbing efficiency. Such phenomenon calls Light Trapping, locking up the light on the surface of solar cell for a long time. Light is a vital factor to plants in the nature. Plants grow up through the photosynthesis that absorbing light for growth and propagation. So, plants make a effort how can absorb more the light in poor surroundings. This study set up a goal that imitates the minute surface structure of plants and applies to the existing solar cells's surface structure, so it can improve the efficiency of absorbing light. We used Light Tools software analyzing geometrical optics to analyze efficiency about new designed textures on the computer. We made a comparison between existing textures and new designed textures. Consequently, new designed textures were advanced efficiency, absorbing rates of light increasing about 7 percent. In comparison with existing and new textures, advancing about 20 percent in the efficient aspect.

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The Spatial Variation Measurement of Multi-Centric Structure in Busan Metropolitan City (부산광역시 다핵구조의 공간적 변동성 측정)

  • Kim, Ho-Yong
    • Spatial Information Research
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    • v.20 no.2
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    • pp.93-103
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    • 2012
  • Recently metropolitan cities pursue multi centric urban spatial structure for sustainable development and efficient urban management. Thus, this study calculated population potential using data on population distributed among road nodes for the last 50 years, and based on the results. We measured the spatial variability of the multi centric structure of Busan Metropolitan City. According to the results, the multi centralization process has been continued up to recently in Busan Metropolitan City. As population potential is concentrated on sub centers, Hadan, Gupo and Haeundae areas were playing an increasingly powerful role as the center of the respective district, and Sasang and Dongrae had been losing their role as the center of their respective districts since 2000 and 1990, respectively. Additionally, in all the multi centric districts except Haeundae was observed the increase of oblongity, which is the change of spatial structure in an unbalanced way toward a specific area or direction.

A study on the Transformation Process of Traditional Small City Structure in Jeollabuk-Do (근대(近代) 도시화(都市化)에 따른 전라도(全羅道) 전통(傳統) 소도읍(小都邑)의 공간구조변화과정(空間構造變化過程) 연구(硏究))

  • Lee, Kyung-Chan
    • Journal of architectural history
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    • v.11 no.3 s.31
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    • pp.21-34
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    • 2002
  • This study is to analyse the transformation process of spatial structure of traditional small city structure in Jeollabuk-Do in the process of modern urbanization between 19th century and the year 2000. The small cities, IM-PI, YONG-AN, YEO-SAN, OK-GOO, GO-SAN, MU-JANG, GUM-MA, GO-BU, which have been local administrative center in CHO-SUN dynasty, have role of local administrative center of subdivision of country-myon, except OK-GOO. The method of this study is to investigate the transformation process of spatial structural elements of with the actual field surveys, the analysis of Gunhyun map made in 1872, land registration maps in 1910s and 2000, and various topological maps. The elements of analysis are the topological site and geographical situation conditions, the urbanized areas, the street systems, the function of streets, the focal points of urban land use, the land use systems, and the location of major facilities such as administration facilities, markets, bus terminals. The analytical point of view and the results are as follows. There is strong relationship between the transformation of internal matrix route system and the growth pattern of urbanized areas, Especially on the contrary to the matrix route with East-West direction which has the role of checking the growth of urbanized area, the South-North direction route acts as the leading line of the growth. The focal points structure of urban land use shows transformation process from the point of central space of administrative district in front of Nae-A, to the access point to administrative district or to the access point to housing and neighborhood commercial area. From the point of functional area structure and major facilities location, line-type commercial area is developed along the line of central axis route and access route to administrative district. Especially direction of the growth of commercial area is strongly connected with the interrelationship between the study area and its neighboring cities. Pattern of commercial district development is varied with the direction of matrix route. That is, commercial district, which shows one side development pattern along the East-West direction route, is developed on both sides of street along the South-North direction route.

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LMDI Decomposition Analysis for GHG Emissions of Korea's Manufacturing Industry (LMDI 방법론을 이용한 국내 제조업의 온실가스 배출 요인분해분석)

  • Kim, Suyi;Jung, Kyung-Hwa
    • Environmental and Resource Economics Review
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    • v.20 no.2
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    • pp.229-254
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    • 2011
  • In this paper, we decomposed Greenhouse-Gas emissions of Korea's manufacturing industry using LMDI (Log Mean Divisia Index) method. Changes in $CO_2$ emissions from 1991 to 2007 studied in 5 different factors, industrial production (production effect), industry production mix (structure effect), sectoral energy intensity (intensity effect), sectoral energy mix (energy-mix effect), and $CO_2$ emission factors (emission-factor effect). By results, the structure effect and intensity effect has a role of reducing GHG emissions and The role of structure effect was bigger than intensity effect. The energy mix effect increased GHG emissions and emission-factor effect decreased GHG emissions. By time series analysis, IMF regime affected the GHG emission pattern. the structure effect and intensity effect in that regime was getting worse. After 2000, in the high oil price period, the structure effect and intensity effect is getting better.

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A Study on the Supporting Method of the Nemok-dori (내목도리 지지 방식에 관한 연구)

  • Heo, Kyoung-Do;Chung, Myung-Sup
    • Journal of the Architectural Institute of Korea Planning & Design
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    • v.36 no.3
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    • pp.69-78
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    • 2020
  • This study is designed to find out the role and relation of the Nemok-dori support members in order to clearly specify the structure of the Dapogye architecture which adopts the Nemok-dori. The dori at the eaves in the Dapogye architecture was expanded to include Oemok-dori, Jusim-dori and Nemok-dori in cooperation with the bracket. The Oemok-dori is used to lengthen the eaves and the Jusim-dori makes the reasonable transfer of loads while the Namok-dori contributes to the stability of the building through the balancing of the bracket. Nemok-dori is located higher than Oemok-dori or Jusim-dori, depending on the slope of Jangyeon and the distance of Chulmok. But as it is not directly supported by bracket or beam, it needs an independent support. The vertical support of Nemok-dori is selectively involved with Cheomcha, lower Jangyeo, support Wall and upper Jangyeo. As the time went by, the vertical height increased, thus making the omitted members less. The horizontal support of Nemok-dori is made in various ways. There are also special cases such as the Nemok-dori □ type chain structure for small rectangular buildings, the 'Nemok-dori = Jung-dori' type for the buildings having small sides and the 'Nemok-dori = Meongechangbang' type appearing on the lower part of the Bankanmulrim type middle height buildings. The horizontal support of Nemok-dori usually uses either the support of the Toeryang type member, the support of beam directed Hwaban or the support through overlaying of internal Jegong. As the time went by and the number and distance of Chulmok increased, the multiple support structures acted together rather than as one support structure. Nemok-dori got stabilized as it has both the vertical and horizontal supports and this support structure also has he role of decoration.

Coherent Structure Extraction from 3-Dimensional Isotropic Turbulence Velocity Field Using Discrete Wavelet Transform (이산 Wavelet 변환을 이용한 3차원 등방성 난류속도장의응집구조 추출)

  • Lee, Sang-Hwan;Jung, Jae-Yoon
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.28 no.9
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    • pp.1032-1041
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    • 2004
  • In this study we decompose the 3-dimensional velocity field of isotropic turbulent flow into the coherent and the incoherent structure using the discrete wavelet. It is shown that the coherent structure, 3% wavelet modes, has 98% energy and 88% enstrophy and its statistical characteristics are almost same as the original turbulence structure. And it is confirmed that the role of the coherent structure is that it produces the turbulent kinetic energy at the inertia range then transfers energy to the dissipation range. The incoherent structure, with residual wavelet modes, is uncorrelated and has the Gaussian probability density function but it dissipates the kinetic energy in dissipation range. On the procedure, we propose a new but easy way to get the threshold by applying the energy partition percentage concept about coherent structure. The vorticity field extracted from the wavelet-decomposed velocity field has the same structure as the result of the precedent studies which decomposed vorticity field directly using wavelet. Therefore it has been shown that velocity and vorticity field are on the interactive condition.

A Numerical Study on Propagation Characteristics of Dam-break Wave through a Porous Structure (다공성 구조물을 통과하는 댐 붕괴파의 전파특성에 관한 수치적 연구)

  • Jeong, Woochang
    • Journal of Korea Water Resources Association
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    • v.47 no.1
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    • pp.11-24
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    • 2014
  • In this study, the characteristics of the propagation of dam-break wave through a porous structure in a water tank is numerically analyzed by using the three-dimensional numerical model (ANSYS CFX model). As results of comparison between the existing measured and simulated water depth distributions in and around a porous structure, the agreement is relatively well satisfied. Moreover, for the case of the presence in part of a porous structure in a water tank, the three-dimensional flow structure is numerically analyzed In general, compared with in the area with a porous structure, the abrupt variation of water depth occurs in the area without a porous structure. It is shown that the porous structure can play a role to decrease the abrupt variation of water depth.

A Study of Predictors of Children's Dual Gender Identity (아동의 양성형 성역할 정체감 예측요인)

  • Hong, Yean-Ran;Chei, Chung-Suk;Park, Jin-Ok
    • The Korean Journal of Emergency Medical Services
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    • v.9 no.1
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    • pp.5-13
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    • 2005
  • Purpose : The purpose of this study was to investigate dual gender identity, masculine gender identity, feminine gender identity, undifferentiated gender identity with related to Sex, home environments, parental child-rearing attitude of warmth, parental child-rearing attitude of control, role division of parents and determine predictors for dual gender identity. Method : Study subjects were $6^{th}$ grade of primary students with 2,118. Data was collected from Oct to Nov 2003 by using structured questionnaire. Results : ${\cdot}$ Among the children, 345 had masculine gender identity, 529 had feminine gender identity, 526 had undifferentiated gender identity, and 718 had dual gender identity. ${\cdot}$ There were significant differences in the children's sex, mother's age, father's age, mother's educational level, father's educational level, existence of mother's job, father's job, social economic status, sex of siblings, mother's job satisfaction, family structure, family atmosphere, child-rearing attitude(warmth and control), role division of parents($p{\leq}0.001$) among 4 groups. ${\cdot}$ The significant predictors for dual gender identity were children's sex (OR = 0,196, P =0.001), father's age(OR = 31.053, p = 0.020), mother's educational level(OR = 43,980, p = 0.001), father's job(OR=27.465, p = 0.001), social economic status(OR=O.941, p=0.001), sex of siblings(OR = 0.329, p = 0.005), mother's job satisfaction(OR = 0.673, p =0.001), family structure(OR = 0.887, p = 0.001), family atmosphere(OR = 23.786, p = 0.001), parental Child-rearing attitude of warmth(OR = 8.043, p = 0.001) and child-rearing attitude of control(OR = 0.666, p = 0.005), role division of parents(OR = 3.009, p = 0.001). Conclusions : These findings suggest the necessity of broad understandings about factors which influence dual gender role, and construction of combinative model. Also they suggest parent education for establishment of children's dual gender identity.

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