• Title/Summary/Keyword: risk-sensitive

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Preliminary Research on the Implementation of Information of Human Facial Part Required for the 3D Printing of Eye Shield (안구차폐체 제작에 필요한 안면부 3차원 정보 구현의 기초연구)

  • Choi, Seokyoon
    • Journal of the Korean Society of Radiology
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    • v.13 no.7
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    • pp.955-960
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    • 2019
  • The Computed tomography (CT) scan can have high radiation in a few tests, and this risk is significant given that it is often repeated in one patient. In children, the incidence of radiation-induced cancer is reported because organs are growing, are more sensitive to radiation. 3D printing has recently been studied to be applied to various applications as a research field for 3D printing applications, research on fabrication of radiation shields and materials has been conducted. The purpose of the 3D printer is to replace the existing panel-type shields and to make customized designs according to the shape of the human body. Therefore, research on 3D information processing to be input to the 3D printer is also necessary. In this study, 3D data of the human body surface, which is the preliminary step of the manufacture of patient-specific eye shield using stereo vision depth map technology, was studied. This study aims to increase the possibility of three-dimensional output. As a result of experimenting with this method, which is relatively simple compared with other methods of 3D information processing, the minimum coordinates for 3D information are extracted. The results of this study provided the advantages and limitations of stereo images using natural light and will be the basic data for the manufacture of eye shields in the future.

Effects of Areal Interpolation Methods on Environmental Equity Analysis (면내삽법이 환경적 형평성 분석에 미치는 영향)

  • Jun, Byong-Woon
    • Journal of the Korean association of regional geographers
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    • v.14 no.6
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    • pp.736-751
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    • 2008
  • Although a growing number of studies have commonly used a simple areal weighting interpolation method to quantify demographic characteristics of impacted areas in environmental equity analysis, the results obtained are inevitably imprecise because of the method's unrealistic assumption that population is evenly distributed within a census enumeration unit. Two alternative areal interpolation methods such as intelligent areal weighting and regression methods can account for the distributional biases in the estimation of impacted populations by making use of additional information about the geographic distribution of population. This research explores five areal interpolation methods for estimating the population characteristics of impacted areas in environmental equity analysis and evaluates the sensitivity of the outcomes of environmental equity analysis to areal interpolation methods. This study used GIS techniques to allow areal interpolation to be informed by the distribution of land cover types, as inferred from a satellite image. in both the source and target units. Independent samples t-test statistics were measured to verify the environmental equity hypothesis while coefficients of variation were calculated to compare the relative variability and consistency in the socioeconomic characteristics of populations at risk over different areal interpolation methods. Results show that the outcomes of environmental equity analysis in the study area are not sensitive to the areal interpolation methods used in estimating affected populations, but the population estimates within the impacted areas are largely variable as different areal interpolation methods are used. This implies that the use of different areal interpolation methods may to some degree alter the statistical results of environmental equity analysis.

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Numerical Sensitivity Analysis on Hydraulic Characteristics by Dredging in Upstream of Abrupt Expansion Region (급확대 구간에서 준설영향으로 인한 상류 수리특성 변화에 대한 민감도 분석)

  • Jeong, Seok Il;Ryu, Kwang Hyun;Lee, Seung Oh
    • Journal of the Korean Society of Safety
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    • v.32 no.4
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    • pp.46-52
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    • 2017
  • Sediment exchange in river has been affected by artificial changes such as dredging and abnormal climate changes like intense rainfall. Over last decades in Korea, there were many constructions, restoration or rehabilitation in rivers. Therefore, deposition and erosion become more actively occurred than before, which may threaten the river safety such as flood defense. For safety's sake, the dredging of river bed, which is considered as the most typical measure, has been increased to extend hydraulic conveyance compared with previous conditions. However, since it might change the sediment mechanism, there would be another risk at which unexpected side effects such as headward erosion could be occurred. Particularly, sedimentation at abrupt expansion region is able to lead to hydraulic characteristics like water elevation in the upstream region in the beginning of dredging, which, however, has been barely studied in this field. Therefore in this study, the relationship between sediment mechanism at dredging section and hydraulic characteristics in upstream region were presented through numerical simulations in the idealized abruptly widen channel using Delft3D. The ideal channel of 2,000 m length with each side angle of 45 degrees at abruptly widen expansion region was employed to consider the sediment angle of repose. The sensitivity analysis was performed on the dimensionless factors consisted of upstream and downstream depths($h_u$, $h_d$), width($w_u$, $w_d$), water level(H), flow rate(Q) and discharge of sediment($Q_s$). And the sedimentation amount at dredging and the upstream hydraulic characteristics were investigated through that analysis. It showed that $h_d/h_u$, $H/h_u$ and $w_d/w_u$ were more influential in sequence of effect on sedimentation amount, while $h_d/h_u$, $w_d/w_u$ and $H/h_u$ on upstream region. It means that $h_d/h_u$ was revealed as the most significant factors on sedimentation, also it would most highly affect the rising of water level upstream.

Evaluation of Chromosomal Alteration in Electrical Workers Occupationally Exposed to Low Frequency of Electro Magnetic Field (EMFs) in Coimbatore Population, India

  • Balamuralikrishnan, Balasubramanian;Balachandar, Vellingiri;Kumar, Shanmugam Suresh;Stalin, Nattan;Varsha, Prakash;Devi, Subramaniam Mohana;Arun, Meyyazhagan;Manikantan, Pappuswamy;Venkatesan, Chinnakulandhai;Sasikala, Keshavarao;Dharwadkar, Shahnaz N.
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.6
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    • pp.2961-2966
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    • 2012
  • Extremely low frequency electro magnetic fields (EMFs) have been classified as possibly carcinogenic to humans by the International Agency for Research on Cancer. An increased number of chromosomal alterations in peripheral lymphocytes are correlated with elevated incidence of cancer. The aim of the present study was to assess occupationally induced chromosomal damage in EMF workers exposed to low levels of radiation. We used conventional metaphase chromosome aberration (CA) analysis and the micronucleus (MN) assay as biological indicators of non ionizing radiation exposure. In the present study totally 70 subjects were selected including 50 exposed and 20 controls. Informed written consent was obtained from all participants and the study was performed in accordance with the Declaration of Helsinki and the approval of the local ethical committee. A higher degree of CA and MN was observed in exposed subjects compared to controls, the frequency of CA being significantly enhanced with long years of exposure (P<0.05). Moreover increase in CA and MN with age was noted in both exposed subjects and controls, but was significantly greater in the former. The results of this study demonstrated that a significant induction of cytogenetic damage in peripheral lymphocytes of workers occupationally exposed to EMFs in electric transformer and distribution stations. In conclusion, our findings suggest that EMFs possess genotoxic capability, as measured by CA and MN assays; CA analysis appeared more sensitive than other cytogenetic end-points. It can be concluded that chronic occupational exposure to EMFs may lead to an increased risk of genetic damage among electrical workers.

Affecting Factors of Insulin Resistance in Obese Children and Adolescents (소아 및 청소년 비만증에서 인슐린 저항성에 미치는 요인)

  • Kim, Duk Hee;Eun, Ho Seon;Choi, In Kyung;Kim, Ho Seung;Cha, Bong Soo;Kim, Dong Kee
    • Clinical and Experimental Pediatrics
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    • v.48 no.10
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    • pp.1076-1081
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    • 2005
  • Purpose : Insulin resistance is the most important risk factor linked to the development of impaired glucose tolerance(IGT), diabetes mellitus and cardiovascular diseases in childhood and adolescent obesity, The purpose of this study was to see whether insulin resistance of obese adolescent is higher than that of obese children. and to analyze gender difference and affecting factors of insulin resistance. Methods : Of the 9,837 school children from 5 to 16 tears old, 92 obese children and 187 adolescent, underwent a two-hour oral glucose tolerance test and plasma glucose, insulin, lipid profiles, leptin and high sensitive C-reactive protein(hs-CRP) were measure. Results : Plasma insulin levels of female were higher compared to those of males during oral glucose tolerance test(P<0.05). Four(4.3%) in obese children and twenty five(13.3%) in obese adolescents met the criteria of IGT. Female, leptin, adiponectin and triglyceride concentrations were strongly correlated with homeostatic model assessment insulin-resistance(HOMA-IR) by multiple linear regression analysis(P<0.05). Conclusion : Obese adolescents might have higher insulin concentrations compared to obese children and obese girls higher insulin concentrations than obese boys. Obese boys and children with impaired glucose tolerance have higher insulin concentrations than those with normal glucose tolerance. HOMA-IR was significantly correlated with female, plasma leptin, adiponectin and triglyceride concentrations.

Mapping of Drought Index Using Satellite Imagery (위성영상을 활용한 가뭄지수 지도제작)

  • Chang, Eun-Mi;Park, Eun-Ju
    • Journal of Korean Society for Geospatial Information Science
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    • v.12 no.4 s.31
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    • pp.3-12
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    • 2004
  • It is necessary to manage water resources in rural areas in order to achieve proper development of new water resources, sustainable usage and reasonable distribution. This paper aims to analyze multi-temporal Landsat-7 ETM+data for soil moisture that is essential for crops in Ahnsung area. The ETM data was also fused with KOMPSAT-1 images in order to be used as backdrop watershed maps at first. Multi-temporal Images showed also the characteristics of soil moisture distribution. Images taken in April showed that rice paddy had as low reflectance as artificial features. Compared with April scenes, those taken in Hay and June showed wetness index increased in the rice paddies. The mountainous areas have almost constant moisture index, so the difference between the dates was very low while reservoirs and livers had dramatic changes. We can calculate total potential areas of distribution of moisture content within the basin and estimate the areas being sensitive to drought. Finally we can point out the sites of small rice paddies lack of water and visualize their distribution within the same basin. It can be said that multi-temporal Landsat-7 ETM+ and KOMPSAT data can be used to show broad drought with quick and simple analysis. Drought sensitiveness maps may enable the decision makers on rural water to evaluate the risk of drought and to measure mitigation, accompanied with proper data on the hydrological and climatic drought.

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Antibiotic Resistances of Enterococcus Isolated from Salad and Sprout (샐러드와 새싹채소에서 Enterococcus의 분리와 항생제 내성특성)

  • Kang, Tae-Mi;Cho, Sun-Kyung;Park, Jong-Hyun
    • Microbiology and Biotechnology Letters
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    • v.36 no.2
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    • pp.142-148
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    • 2008
  • To evaluate the antibiotic resistance of Enterococcus from salad and sprout, Enterococcus were isolated and identified from 47 salad samples and 37 sprout samples, and then their antibiotic resistances were analyzed. Ninety five Enterococcus, 41 strains from salad and 54 strains from sprout, were ultimately isolated. The frequent Enterococcus in salad and sprout were E. gallinarum, E. faecalis, E. faecium, E. hirae, and E. avium. Minimum inhibitory concentrations of the isolates for vancomycin were below $4{\mu}g/mL$, which were not high levels of resistance. All Enterococcus proved to be resistant to streptomycin and chloramphenicol. Twenty two percentage of the isolates were resistant to penicillin, however, almost the isolates were sensitive to tetracycline. Eighteen percentage of the isolates were resistant to erythromycin. All E. faecium and E. faecalis were found to be ampicillin-resistant, and seven E. faecalis and five E. faecium were resistant to rifampicin. Overall antibiotic resistances of Enterococcus isolates were relatively low and low resistance to vancomycin was similar to those evidenced by Enterococcus isolated from the other foods. Therefore, there may be no special risk from the antibiotics resistances of Enterococcus and especially vancomycin-resistant Enterococcus from the fresh-cut salads and the sprouts.

Factors predicting radiation pneumonitis in locally advanced non-small cell lung cancer

  • Kim, Myung-Soo;Lee, Ji-Hae;Ha, Bo-Ram;Lee, Re-Na;Lee, Kyung-Ja;Suh, Hyun-Suk
    • Radiation Oncology Journal
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    • v.29 no.3
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    • pp.181-190
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    • 2011
  • Purpose: Thoracic radiotherapy is a major treatment modality of stage III non-small cell lung cancer. The normal lung tissue is sensitive to radiation and radiation pneumonitis is the most important dose-limiting complication of thoracic radiation therapy. This study was performed to identify the clinical and dosimetric parameters related to the risk of radiation pneumonitis after definitive radiotherapy in stage III non-small cell cancer patients. Materials and Methods: The medical records were reviewed for 49 patients who completed definitive radiation therapy for locally advanced non-small cell lung cancer from August 2000 to February 2010. Radiation therapy was delivered with the daily dose of 1.8 Gy to 2.0 Gy and the total radiation dose ranged from 50.0 Gy to 70.2 Gy (median, 61.2 Gy). Elective nodal irradiation was delivered at a dose of 45.0 Gy to 50.0 Gy. Seven patients (14.3%) were treated with radiation therapy alone and forty two patients (85.7%) were treated with chemotherapy either sequentially or concurrently. Results: Twenty-five cases (51.0%) out of 49 cases experienced radiation pneumonitis. According to the radiation pneumonitis grade, 10 (20.4%) were grade 1, 9 (18.4%) were grade 2, 4 (8.2%) were grade 3, and 2 (4.1%) were grade 4. In the univariate analyses, no clinical factors including age, sex, performance status, smoking history, underlying lung disease, tumor location, total radiation dose and chemotherapy were associated with grade ${\geq}2$ radiation pneumonitis. In the subgroup analysis of the chemotherapy group, concurrent rather than sequential chemotherapy was significantly related to grade ${\geq}2$ radiation pneumonitis comparing sequential chemotherapy. In the univariate analysis with dosimetric factors, mean lung dose (MLD), $V_{20}$, $V_{30}$, $V_{40}$, MLDipsi, $V_{20}$ipsi, $V_{30}$ipsi, and $V_{40}$ipsi were associated with grade ${\geq}2$ radiation pneumonitis. In addition, multivariate analysis showed that MLD and V30 were independent predicting factors for grade ${\geq}2$ radiation pneumonitis. Conclusion: Concurrent chemotherapy, MLD and $V_{30}$ were statistically significant predictors of grade ${\geq}2$ radiation pneumonitis in patients with stage III non-small cell lung cancer undergoing definitive radiotherapy. The cutoff values for MLD and $V_{30}$ were 16 Gy and 18%, respectively.

AN EXPERIMENTAL STUDY OF ELECTROPHYSIOLOGICAL AND HISTOLOGICAL ASSESSMENT ON THE INJURY TYPES IN RABBIT INFERIOR ALVEOLAR NERVE (가토의 하치조 신경 손상 형태에 따른 전기생리학적 및 조직학적 변화에 관한 실험적 연구)

  • Lee, Jae-Eun;Lee, Dong-Keun
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.18 no.4
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    • pp.679-700
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    • 1996
  • Inferior alveolar nerve dysfunction may be the result of trauma, disease, or iatrogenic injury. Inferior alveolar nerve injury is inherent risk in endodontic therapy, orthognathic surgery of the mandible, and extraction of mandibular teeth, particularly the third molars. The sensory disturbances of inferior alveolar nerve associated with such injury have been well documented clinical problem that is commonly evaluated by several clinical sensory test including Tinels sign, Von Frey test(static light touch detection), directional discrimination, two-point discrimination, pin pressure nociceptive discrimination, and thermal test. These methods used to detect and assess inferior alveolar nerve injury have been subjective in nature, relying on the cooperation of the patients. In addition, many of these techniques are sensitive to differences in the examiners experience and skill with the particular technique. Data obtained at different times or by different examiners are therefore difficult to compare. Prior experimental studies have used electro diagnostic methods(sensory evoked potential) to objectively evaluate inferior alveolar nerve after nerve injury. This study was designed with inferior alveolar nerve of rabbit. Several types of injury including mind, moderate, severe compression and perforation with 19 gauze, 21 gauze needle and 6mm, 10mm traction were applied for taking the sesory evoked ppterntial. Latency and amplitude of injury rabbit inferior alveolar nerve were investigated with sensory evoked potential using unpaired t-test. The results were as follows : 1. Intensity of threshold (T1) was $128{\pm}16{\mu}A$ : latency, $0.87{\pm}0.07$ microsecond : amplitude, $0.4{\pm}0.1{\mu}V$ : conduction velocity, 23.3 m/s in sensory evoked potential of uninjured rabbit inferior alveolar nerve. 2. Rabbit inferior alveolar nerve consists of type II and III sensory nerve fiber. 3. Latency was increased and amplitude was decreased in compression injury. The more injured, the more changed in latency and amplitude. 4. Findings in perforation injury was similar to compression injury. Waveform for sensory evoked potential improved by increasing postinjured time. 5. Increasing latency was prominent in traction injury rabbit inferior alveolar nerve. 6. In microscopic histopathological findings, significant degeneration and disorganization of the internal architecture were seen in nerve facicle of severe compression and 10mm traction group. From the above findings, electrophysiological assessment(sensory evoked potential) of rabbit injured inferior alveolar nerve is reliable technique in diagnosis and prognosis of nerve injury.

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Reduced Sensitivities of the Pear Scab Fungus (Venturia nashicola) Collected in Ulsan and Naju to Five Ergosterol-biosynthesis-inhibiting Fungicides (울산과 나주에서 채집한 배나무 검은별무늬병균의 ergosterol 생합성 저해제 5종에 대한 감수성 저하)

  • Kwon, Soo-Mean;Yeo, Moo-Ill;Choi, Se-Hoon;Kim, Gun-Woong;Jun, Kyung-Jin;Uhm, Jae-Youl
    • Research in Plant Disease
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    • v.16 no.1
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    • pp.48-58
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    • 2010
  • In Korea, EBI fungicides which are highly effective for control of pear scab and rust but of high risk for development of resistance have been frequently sprayed by majority of pear growers. To detect any possible resistance or reduced sensitivity in the field strains of scab fungus to five EBIs, difenoconazole, fluquinconazole, flusilazole, fenarimole and hexaconazole, sensitivity tests were conducted with fungal specimens collected in Ulsan and Naju where scab usually occurs and EBIs have been intensively sprayed for many years. As the strains for which $EC_{50}$ values of the EBIs were largely shifted from those of base-line were occasionally found, the resistant or less sensitive strains were supposed to be distributed. In the activity test for the EBIs by artificial inoculation, in which EBI-treated pear leaves on the potted seedlings were inoculated with fungal spores collected in the two regions, development of resistances to EBIs were confirmed. Since the fungal spores collected at 4 and 2 orchards in Naju and Ulsan, respectively, produced much higher disease incidence on the leaves treated with hexaconazole than those on the untreated control, those fungal specimens were determined as resistant to hexaconazole. Similar results were also obtained with two specimens from Ulsan for flusilazole.