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Association Between the hsa-mir-27a Variant and Breast Cancer Risk: a Meta-analysis

  • Wang, Bin;Ma, Ning;Wang, Yajie
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.12
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    • pp.6207-6210
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    • 2012
  • Introduction: Although a number of studies were published in the past several years on associations between hsa-mir-27a and cancer risk, the findings remain conflicting rather than conclusive. To derive a more precise effect on the association between SNP hsa-mir-27a rs895819 and breast cancer risk, we conducted a meta-analysis for the first time. Materials and Methods: Through retrieval from PubMed for the period up to August 2012, a total of four studies were identified with 3,287 cases and 4,298 controls for SNP hsa-mir-27a rs895819. We calculated summary odds ratio (ORs) and corresponding 95% confidence intervals (CIs) using a fixed effects model (when the heterogeneity was absent, P>0.10). Otherwise, the random-effects model was used. Results: We found that hsa-mir-27a rs895819 polymorphism also did not reveal any relationship with breast cancer susceptibility (AG versus AA: OR = 0.98; 95%CI, 0.73-1.32; GG versus AA: OR = 0.86; 95% CI, 0.72-1.03; AG/GG versus AA: OR = 0.92; 95% CI, 0.74-1.14), while significantly decreased risk was found among Europeans in AG versus AA and AG/GG versus AA models tested (AG versus AA: OR = 0.83; 95%CI, 0.72-0.97; GG versus AA: OR = 0.86; 95% CI, 0.71-1.05; AG/GG versus AA: OR = 0.84; 95% CI, 0.75-0.94). Conclusion: These findings suggest that hsa-mir-27a rs895819 polymorphism may play an important role in breast cancer development.

Implementation of Worksheet System for Fashion Design (패션디자인 작업지시서 작성을 위한 시스템의 구현)

  • Lee Hea-Jung;Lee Min-Kyu;Kim Young-un;Jung Sung-tae;Lee Yong-Ju;Cho Jin-Ei;Joung Suck-tea
    • Journal of the Korea Society of Computer and Information
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    • v.9 no.4 s.32
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    • pp.99-107
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    • 2004
  • In a field of clothing fashion design within the country, CADs and diagraming programs are existed variously. However, Connection of producton line through the worksheet is insufficient. This research implement design and worksheet system grafted on database system. This system can be completed desige through the fashion design system and made out worksheet at the same time. Also, It is possible that designer utilize more quickly and easily find intend to use the data because this system provide retrieval function for existed data with user. A special feature of the system is easy interface(GUI) for user, support of tool for detail, utilize for stored data, printing support for off-line output, comfortable framework for record of clothes size and etc.

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Effect of Removal of Follicles through Repeated Transvaginal Follicle Aspiration on Subsequent Follicular Populations in Murrah Buffalo (Bubalus bubalis

  • Akshey, Y.S.;Palta, P.;Manik, R.S.;Vivekananad, Vivekananad;Chauhan, M.S.
    • Asian-Australasian Journal of Animal Sciences
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    • v.18 no.5
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    • pp.632-636
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    • 2005
  • This study was conducted to investigate the effects of removal of all ovarian follicles through repeated transvaginal follicle aspiration (TVFA) on the subsequent follicular populations in buffaloes. This information is crucial for determining the optimum time interval between successive aspirations for recovering oocytes from live buffaloes through Transvaginal Oocyte Retrieval (TVOR). The oestrus of cycling buffaloes (n=5) were synchronized by a single PGF injection schedule. All the ovarian follicles were removed once every 7 days for 6 weeks through TVFA, starting from Day 7 of the oestrous cycle (Day 0 = day of oestrus). The number and size of individual ovarian follicles was recorded at Day 3 and Day 5 (Day 0 = day of TVFA) through transrectal ultrasonography. The follicles were classified on the basis of their diameter as small (3-5 mm), medium (6-9 mm) and large ($\geq$10 mm). There was no difference in the number of small and medium follicles, and the number of total follicles between Day 3 and Day 5. However, the number of large follicles was significantly higher (p<0.05) at Day 5 than that at Day 3. There was a significant (p<0.05) decrease in the proportion of small follicles and an increase (p<0.05) in the proportion of large follicles from Day 3 to Day 5, with no change in the proportion of medium follicles. The number of total follicles at Day 3 or Day 5 did not differ during the 6 TVFA sessions. It can be concluded that an interval of 3 days is more suitable than that of 5 days between successive aspirations for recovering oocytes through TVOR in a twice weekly schedule and that repeated removal of follicles through TVFA does not adversely affect the number of total follicles 3 or 5 days after TVFA.

Retrieval of Thermal Tropopause Height using Temperature Profile Derived from AMSU-A of Aqua Satellite and its Application (Aqua 위성 AMSU-A 고도별 온도자료를 이용한 열적 대류권계면 고도 산출 및 활용)

  • Cho, Young-Jun;Shin, Dong-Bin;Kwon, Tae-Yong;Ha, Jong-Chul;Cho, Chun-Ho
    • Atmosphere
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    • v.24 no.4
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    • pp.523-532
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    • 2014
  • In this study, thermal tropopause height defined from WMO (World Meteorological Organization) using temperature profile derived from Advance Microwave Sounding Unit-A (AMSU-A; hereafter named AMSU) onboard EOS (Earth Observing System) Aqua satellite is retrieved. The temperature profile of AMSU was validated by comparison with the radiosonde data observed at Osan weather station. The validation in the upper atmosphere from 500 to 100 hPa pressure level showed that correlation coefficients were in the range of 0.85~0.97 and the bias was less than 1 K with Root Mean Square Error (RMSE) of ~3 K. Thermal tropopause height was retrieved by using AMSU temperature profile. The bias and RMSE were found to be -5~ -37 hPa and 45~67 hPa, respectively. Correlation coefficients were in the range of 0.5 to 0.7. We also analyzed the change of tropopause height and temperature in middle troposphere in the extreme heavy rain event (23 October, 2003) associated with tropopause folding. As a result, the distinct descent of tropopause height and temperature decrease of ~8 K at 500 hPa altitude were observed at the hour that maximum precipitation and maximum wind speed occurred. These results were consistent with ERA (ECMWF Reanalysis)-Interim data (potential vorticity, temperature) in time and space.

Motion vector-tracing algorithms of video sequence (비디오 시퀀스의 움직임 추적 알고리즘)

  • 이재현
    • Journal of the Korea Computer Industry Society
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    • v.3 no.7
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    • pp.927-936
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    • 2002
  • This paper presents the extraction of a feature by motion vector for efficient content-based retrieval for digital video. in this paper, divided by general size block for the current frame by video, using BMA(block matching algorithm) for an estimate by block move based on a time frame. but in case BMA appeared on a different pattern fact of motion in the vector obtain for the BMA. solve in this a problem to application for full search method this method is detected by of on many calculations. I propose an alternative plan in this paper Limit the search region to $\pm$15 and search is a limit integer pixel. a result, in this paper is make an estimate motion vector in more accurately using motion vector in adjoin in blocks. however, refer to the block vector because occurrence synchronism. Such addition information is get hold burden receive to transmit therefore, forecasted that motion feature each block and consider for problems for establish search region. in this paper Algorithm based to an examination Motion Estimation method by for motion Compensation is proposed.

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A Study on Building Method of the Construction Industry Thesaurus Using Facet Analysis Method (패싯 분석 기법을 활용한 건설 시소러스 구축 방안에 관한 연구)

  • Hong, Ki-Churl
    • Journal of Korean Library and Information Science Society
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    • v.48 no.1
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    • pp.345-371
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    • 2017
  • Traditionally, the construction industry field is one of the typical fields using facet analysis method. Internationally the facet analysis method is applied to the classification scheme "Uniclass" or thesaurus "Construction Industry Thesaurus(CIT)". In the case of Korea, the facet analysis method is being used in classification scheme "Construction Industry Classification System" but it is difficult to find studies on facet analysis method in thesaurus or building case study. This study aims to establish facet types by introducing building of thesaurus for information retrieval in construction field using facet analysis method and to suggest building plan of thesaurus in construction field using facet analysis method. In this paper, We establish the 11 top facets(agent/patient, artifacts, abstract, material, parts/component, works, attribute, media, process, space, time) and the 13 subfacet as rudimental facets and suggest building plan according to thesaurus building procedure which is suggested by International Standard(ISO 25964-1). The result of this study is expected to apply to facet based thesaurus. And it is also expected to reuse in Taxonomy or Ontology etc. and to use in interoperability with the classification scheme of Construction filed.

Efficacy of Balloon-Guiding Catheter for Mechanical Thrombectomy in Patients with Anterior Circulation Ischemic Stroke

  • Oh, Jae-Sang;Yoon, Seok-Mann;Shim, Jai-Joon;Doh, Jae-Won;Bae, Hack-Gun;Lee, Kyeong-Seok
    • Journal of Korean Neurosurgical Society
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    • v.60 no.2
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    • pp.155-164
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    • 2017
  • Objective : To evaluate the efficacy of balloon guiding catheter (BGC) during thrombectomy in anterior circulation ischemic stroke. Methods : Sixty-two patients with acute anterior circulation ischemic stroke were treated with thrombectomy using a Solitaire stent from 2011 to 2016. Patients were divided into the BGC group (n=24, 39%) and the non-BGC group (n=38, 61%). The number of retrievals, procedure time, thrombolysis in cerebral infarction (TICI) grade, presence of distal emboli, and clinical outcomes at 3 months were evaluated. Results : Successful recanalization was more frequent in BGC than in non-BGC (83% vs. 66%, p=0.13). Distal emboli occurred less in BGC than in non-BGC (23.1% vs. 57.1%, p=0.02). Good clinical outcome was more frequent in BGC than in non-BGC (50% vs. 16%, p=0.03). The multivariate analysis showed that use of BGC was the only independent predictor of good clinical outcome (odds ratio, 5.19 : 95% confidence interval, 1.07-25.11). More patients in BGC were successfully recanalized in internal carotid artery (ICA) occlusion with small retrieval numbers (<3) than those in non-BGC (70% vs. 24%, p=0.005). In successfully recanalized ICA occlusion, distal emboli did not occur in BGC, whereas nine patients had distal emboli in non-BGC (0% vs. 75%, p=0.001) and good clinical outcome was superior in BGC than in non-BGC (55.6% vs. 8.3%, p=0.01). Conclusion : A BGC significantly reduces the number of retrievals and the occurrence of distal emboli, thereby resulting in better clinical outcomes in patients with anterior circulation ischemic stroke, particularly with ICA occlusion.

Two Version Latch Technique for Metadata Management of Documents in Digital Library (전자 도서관에서 문서의 메타데이타 관리를 위한 2 버전 래치 기법)

  • Jwa, Eun-Hee;Park, Seog
    • Journal of KIISE:Databases
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    • v.29 no.3
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    • pp.159-167
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    • 2002
  • Recently, a major issue in the research of metadata is the standardization of metadata format. The new extension capability of metadata in the standardization requires some changes - storing and managing dynamic data consistently. In this paper, we define the characteristics of new metadata and propose a concurrency control called Two Version Latch (2VL). 2VL uses a latch and maintains two versions. Maintaining two versions using latch minimizes conflicts between read operation and write operation. The removal of unnecessary lock holding minimizes refresh latency. Therefore, this algorithm presents fast response time and recent data retrieval in read operation execution. As a result of the performance evaluation, the 2VL algorithm is shown to be better than other algorithms in metadata management system.

Metadata Management Method for Consistency and Recency in Digital Library (디지탈 도서관 환경에서 일관성과 최근성을 고려한 메타데이타 관리 방법)

  • Lee, Hai-Min;Park, Seog
    • Journal of KIISE:Databases
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    • v.27 no.1
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    • pp.22-32
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    • 2000
  • The Digital Library is the integrated system of Information Retrieval System(IRS) and Database Management system(DBMS). In the Digital Library environment where dynamic query and update processes are required, however, the existing transaction management methods cause the following problems. First, since the traditional consistency criteria is too restrictive, it causes increment of query processing time and cannot guarantee the reflection of recency. Second, query result could be unreliable because the consistency criteria between source data and metadata is not defined. This paper models the access to metadata based on Dublin Core as query transactions and update transactions, and gives the efficient method to manage them. Particularly, this paper describes the consistency criteria of metadata which takes it Into consideration the consistency between the result of query transaction and status of source data in the Digital Library, that is different from the consistency criteria in traditional transaction management. It also presents analysis of the view point of query transaction to reflect recency and proposes metadata management to guarantee recency within metadata consistency.

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Computerizing Clinical Laboratory with Clinical Devices Interface : I. With a focus on ABGA(Arterial Blood Gas Analyzer) (임상 의료장비 인터페이스를 이용한 검사실 전산화 구현 : I. ABGA(Arterial Blood Gas Analyser)를 중심으로)

  • Kim, Sun-Chil;Kwon, Deok-Moon
    • Korean Journal of Digital Imaging in Medicine
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    • v.8 no.1
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    • pp.21-26
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    • 2006
  • Hospitals these days are trying to introduce the a practice has recently been generalized in the test or diagnosis process, where test results and images from different test labs are interlinked together. This process is identical to that of physical aspect in EMR process, which computerizes the paper results within the hospital. One of the prerequisites for the process of computerizing test results is the interface between clinical test devices in the test labs. However, due to the variety of prescription inputs, disparity of test result papers, complexity of job in test labs and diversify of interfaces among the different devices, interconnection with the hospital information system is a complicated job. A universal control of clinical test devices which have independent communication protocols has become possible by connecting them with an interface workstation. As for the patients, waiting time for test has been reduced, and, thanks to the synchronized result retrieval system, it has become possible to check the test results on the very day of the test. As a result, the length of hospitalization has been reduced, too. In terms of workflow, as the transfer of charts and transfer of result papers are separated, the embarrassing job of collecting result papers has disappeared. As patients' test appointment and the results processing can be made on-line, extra work for doctors have disappeared. And, thanks to the computerization of test results information management, the job of statistical processing has become convenient.

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