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The Effects of Nokyongsageunhwan Herbal Acupuncture and Oral Administration on the Growth and the Intellectual Development of Rats (녹용사근환약침(鹿茸四斤丸藥鍼) 및 경구투여(經口投與)가 흰쥐의 성장(成長)과 지능발달(知能發達)에 미치는 영향(影響))

  • Kang, Ki-weon;Koh, Hyung-kyun;Lee, Yun-ho
    • Journal of Acupuncture Research
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    • v.20 no.6
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    • pp.45-62
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    • 2003
  • Objective: This study was designed to investigate effects of Nokyongsageunhwan and Nokyongsageunhwan aquapuncuture on body weight, body length, intellectual development Methods: We observed body weight, body length, intellectual development after feeding Nokyongsageunhwan and Nokyongsageunhwan aquapuncuture for thirty three days, and mRNA expressions of GHRF, Somatostatin, IGF-1, NPY were analyzed by RT-PCR method. Results: The results were summarized as follows. 1. Body length was significantly increased in Nokyongsageunhwan herbal acupuncture group compared to normal group and normal saline injection group on 4th week, 2. Lower part of hind leg length was significantly increased in Nokyongsageunhwan oral administration group compared to normal group on 3rd week, and it was significantly increased in Nokyongsageunhwan herbal acupuncture group and Nokyongsageunhwan oral administration group compared to that of normal group on 4th week. 3. As results of observing memory aquisition using Morris water maze system, there was significantly difference in Nokyongsageunhwan oral administration group compared to that of normal group on 4th week. 4. As results of observing retention using Morris water maze system, staying time was significantly increased in Nokyongsageunhwan herbal acupuncture group compared to that of normal group. 5. The somatostatin mRNA expression in the hypothalamus was significantly decreased in Nokyongsageunhwan oral administration group compared to that of normal group. 6. The IGF-1 mRNA expression in the hypothalamus is significantly increased in Nokyongsageunhwan herbal acupuncture group and Nokyongsageunhwan oral administration group compared to that of normal group. 7. The NPY mRNA expression in the hypothalamus was significantly increased in Nokyongsageunhwan oral administration group compared to that of normal group, and it was increased in Nokyongsageunhwan herbal acupuncture group compared to that of normal group, but there was no significant difference. Conclusions: According to the above results, it appears that Nokyongsageunhwan oral administration and Nokyongsageunhwan herbal acupuncture on acupoint GB34 and GB39 showed effects on the growth and the intellectual development of rats.

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Esthetic removable partial denture with implants and resin clasp: Case report (임플란트와 레진 클래스프를 이용한 심미 가철성 국소의치 증례)

  • Kim, Su-Min;Jeon, Young-Chan;Jeong, Chang-Mo;Yun, Mi-Jung;Huh, Jung-Bo
    • The Journal of Korean Academy of Prosthodontics
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    • v.53 no.1
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    • pp.58-65
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    • 2015
  • For the rehabilitation of fully edentulous patients, implant-supported removable partial dentures can be considered as one of the treatment options with complete dentures or implant-supported overdentures. If removable partial dentures are used in combination with a small number of implants placed in strategically important positions, it can offer additional stability, retention and support through implants and reduce a burden of surgical procedures compared with fixed implant-supported prostheses with extensive implant placement. Moreover, the economical benefit can be expected as well. The purpose of this case report is to present a treatment in which an implant-supported removable partial denture was fabricated considering residual alveolar bone status and demands after teeth loss in a patient who had been using a distal extension removable partial denture for a long period of time. In anterior area, fixed prostheses were fabricated with implant placement and in posterior area, short implants provide only support for the removable partial denture. In addition, denture base and clasp were made of thermoplastic acrylic resin. Finally, functionally and aesthetically satisfying treatment results can be achieved.

A Study on the Spatial Information and Location Environment of Dead Coniferous Tree in Subalpine Zone in Jirisan National Park -Focus on Korean Fir(Abies koreana) in Banyabong, Yeongsinbong, Cheonwangbong- (지리산국립공원 아고산대 침엽수 고사개체 공간정보 구축 및 입지환경 분석 - 반야봉, 영신봉, 천왕봉 일원 구상나무를 중심으로-)

  • Park, Hong Chul;Moon, Geon Soo;Lee, Ho;Lee, Na Yeon
    • Korean Journal of Environment and Ecology
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    • v.34 no.1
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    • pp.42-54
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    • 2020
  • This study aimed to analyze the rate of increase and spread patterns of dead trees of the conifer (Abies koreana and others) in subalpine zones by using the high-resolution aerial images in Jirisan National Park around 10 years ago. Furthermore, factors affecting the death of conifer were identified by analyzing the altitude, topographical information, solar radiation, and moisture environment of the site where the dead trees are located. The number of dead trees per unit area increased by two to five times in the Banyabong peak, Yeongsinbong peak, and Cheonwangbong peak in Jirisan National Park over the past decade. The increase was about 2 times in the Banyabong peak, about 3.9 times in the Yeongsinbong peak, and about 5.2 times in the Cheonwangbong peak, indicating the most notable increase in the Cheonwangbong peak. It is estimated that dead trees commonly occurred in the environments where the soil moisture content was low due to the high slope, amount of evaporation was high due to strong solar radiation as the location faced south, and the soil was dry due to strong solar radiation and short rain retention time. In other words, dead conifer trees in subalpine zones were concentrated in dry location environments, and the tendency was the same more than ten years ago.

Activity of Methanogens in the High Rate Anaerobic Digestion of Swine Wastewater Containing High Ammonia (고농도 암모니아를 함유한 돈사폐수의 고율혐기성 소화시 메탄균의 활성연구)

  • Oh, Sae-Eun;Lee, Chae-Young
    • Journal of Korean Society of Environmental Engineers
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    • v.22 no.5
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    • pp.981-987
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    • 2000
  • Upflow anaerobic sludge blanket(UASB) reactor was operated for treating swine wastewater containing high ammonia nitrogen to assess their performance and toxicity of free ammonia concentration. In the reactor, chemical oxygen demand(COD) removed about 70% at $2.6kgCOD/m^3.day$ of organic loading rate(OLR) and 3 days of hydraulic retention time (HRT), while it was decreased when OLR and HRT was maintained $7kg\;COD/m^3.day$ and 2 days, respectively. Also UASB reactor was evaluated the activity of methane producing bacteria(MPB) according to change of free ammonia concentrations, MPB activity of applied sludge in the 500 and $1000mg-N/{\ell}$ of free ammonia concentration was inhibited by 4% and 40%, respectively. This clearly showed that free ammonia concentration less than $500mg-N/{\ell}$ showed no inhibition to MPB in anaerobic treatment of organics, UASB reactor was stabilized easily less than $1000mgVSS/{\ell}$ due to degradation of organic solids by the high activities of anaerobes.

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Behavior of Soluble Microbial Products in a Submerged Membrane Separation Activated Sludge Process (침지형 막분리 활성오니법에 있어서 생물대사성분의 거동)

  • Cha, Gi-Cheol;Lee, Dong-Yeol;Shim, Jin-Kie;Lee, Yong-Moo;Yoo, Ik-Keun;Ann, Seung-Ho
    • Journal of Korean Society of Environmental Engineers
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    • v.22 no.5
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    • pp.959-970
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    • 2000
  • A laboratory-scale experiment was conducted to investigate the effect of soluble microbial products(SMP) on permeate flux in the submerged membrane separation activated sludge process. Continuous and batch filtration test were operated to understand mechanism of relationship between membrane fouling and SMP. Synthetic wastewater(phenol) was used as a carbon source. Hydraulic retention time(HRT) and mixed-liquor volatile suspended solids(MLVSS) of the reactor were kept at 12 hours and 9.000mg VSS/L, respectively. Batch filtration tests ($J_{60}/J_o$) using the mixed liquor from reactor showed that the increase of accumulated SMP concentration in the reactor caused to the decreasing permeate flux and the increasing of the adhesion matters which form cake and gel layer. The resistance value of cake layer was measured $2.9{\times}10^{10}{\sim}4.0{\times}10^{10}(1/m)$, this value showed more significant effect on flux drop than that of among other resistance layers. Batch phenol-degradation experiment was conducted to observe SMP type expected $SMP_{nd}$ and $SMP_{e}$ (SMP resulted from endogenous cell decomposition), these are non-biodegradable high molecular weight organic matter and playa significant role in permeate flux drop. Also, SMP concentration was accumulated as increased of HRT against flux drop.

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A Study on the Physiological and Psychological Factors related to Successful Weaning from a Mechanical Ventilator (기계환기기 이탈의 성공과 관련된 생리적${\cdot}$심리적 요인에 관한 조사 연구)

  • Kim, Cho-Ja;Kim, Hwa-Soon;Jang, Yeon-Soo;Kim, Eun-Sung
    • Journal of Korean Academy of Nursing
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    • v.30 no.4
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    • pp.995-1005
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    • 2000
  • This study was performed to identify the physiological and psychological variables related to successful weaning from a mechanical ventilator. The subjects of this study were 22 patients who received mechanical ventilation therapy for more than 3 days in intensive care units. Before the weaning trial, baseline data for following physiologic variables were obtained: spontaneous respiration rate, blood pressure, pulse rate, PaO2, PaCO2, PEEP, static compliance, minute ventilation, tidal volume, rapid shallow breathing index(f/VT), SaO2, PaO2/FiO2 and mean arterial pressure. During spontaneous breathing, physiologic and psychologic variables such as vital signs, ABG, perspiration, chest retraction, paradoxical respiration, dyspnea, anxiety, confidence and efficacy were measured. Successful weaning was defined as sustaining spontaneous respiration over 24 hours after extubation. Weaning failure was defined as the development of more than one of following signs: (1) hypoxemia, (2) CO2 retention or (3) perspiration, tachypnea, chest retraction, tachycardia, arrhythmia, hypotension or hypertension. Subjects (N=18) who successfully weaned from mechanical ventilator were compared with subjects (N=4) who failed. The results are as follows; Eighteen percents of the subjects failed during the weaning trial. Most subjects in the failed group were mechanically ventilated for long-time. This result shows that the success of weaning is more difficult in long-term ventilation patients. In the baseline data that was measured before weaning trial, the mean score of PaO2 in the successfully weaned group was 121mmHg. This is significantly higher than the mean score of PaO2 in the failed group(95mmHg). However, the scores of pH, tidal volume, f/VT, pulse rates, blood pressure, mean airway pressure, SaO2, and PaCO2 were similar between the two groups. Specially the scores of f/VT index as a predominant predictor for successful weaning were not significant (f/VT=44.4) and (f/VT=47). During spontaneous breathing, the scores of dyspnea and anxiety level in the successfully weaned group were less than those of the failed group. On the contrary, the scores of confidence and efficacy in the successful group were greater than those of the failed group. In conclusion, the baseline data that were measured before weaning trial were similar between the both groups, therefore future studies are needed to focus on searching other variables besides physiological parameters related to weaning outcome.

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A Systematic Review of Randomized Controlled Trials on Acupuncture Treatment for Neck Pain (경항통에 침치료를 시행한 무작위대조군연구(RCT)들에 대한 계통적 연구)

  • Kim, Hyun-Wook;Kim, Sung-Soo;Kang, Jung-Ah;Nam, Dong-Woo;Kim, Eun-Jung;Hong, Kwon-Eui;Kim, Sung-Chul;Lee, Jae-Dong;Kim, Kap-Sung;Lee, Geon-Mok
    • Journal of Acupuncture Research
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    • v.26 no.2
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    • pp.103-123
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    • 2009
  • Objectives : The aim of this study is to review RCTs of acupuncture treatment for neck pain and to establish standards of acupuncture treatment for neck pain. Methods : We searched articles in Pubmed using ICD 10. Study quality was assessed using the FEAS and Jadad score. Results and Conclusions : Three review studies and nineteen clinical trials were searched and reviewed. Among the nineteen clinical trials reviewed, positive outcome was reported in thirteen studies. Most frequently used meridians were GB, BL, SI, GV and LI, The most frequently used acupuncture points were $GB_{20}$, $GB_{21}$, $LI_4$, $BL_{10}$, $GV_{14}$ and $SI_3$. More than two needles were inserted in the studies and needle retention time was more than 10 minutes. The most frequently used needle length was 40mm, and diameter was 0.25mm and 0.30mm. The mean number of treatment sessions were more than 10 times. Frequency of treatment was more than once a week, And treatment duration was more! than 5 weeks. The total FEAS scores ranged from 3 to 15.5, and the mean value was 9.39. Jadad score ranged from 2 to 5, and the mean value was 3.42. The number of studies scoring over three points on the Jadad scale was sixteen.

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Review of Randomized Controlled Trials on Ideal Acupuncture Treatment for Degenerative Knee Osteoarthtritis (RCT논문을 중심으로 한 퇴행성 슬관절염 침구 치료 방법에 대한 고찰)

  • Kim, Eun-Jung;Lee, Seung-Deok;Jung, Chan-Yung;Yoon, Eun-Hye;Jang, Min-Gee;Nam, Dong-Woo;Kim, Hyun-Wook;Lee, Eun-Yong;Kim, Kyung-Ho;Lee, Geon-Mok;Lee, Jae-Dong;Kim, Kap-Sung
    • Journal of Acupuncture Research
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    • v.26 no.2
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    • pp.125-145
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    • 2009
  • Objectives : To analyze the inclusion criteria of participants, control group interventions, and the results of prior studies of acupuncture for OA. Also to identify aspects of the procedure that are associated with positive outcomes in order to establish ideal acupuncture treatment model. And to assess the methodological quality of the trials with modified Jadad score and FEAS in order to evaluate the quality of prior studies and find out whether or not acupuncture has a positive effect in treating OA. Methods : Articles up to the date of November 2008 were searched via computerized databases of PubMed, Journal of Korean Oriental Medicine, The Journal of Korean Acupuncture & Moxibustion Society and Journal of Oriental Rehabilitation Medicine. Bibliographies of reviewed papers were also searched and reviewed. Only randomized controlled trials (RCTs) and systematic reviews concerning the effects of acupuncture or electroacupuncture (EA) on symptoms of osteoarthritis of the human knee, published in English and Korean were included. The acupuncture treatment methods of the reviewed trials were assessed based on STRICTA. And the methodological quality of the trials was assessed by modified Jadad score and FEAS. Results : Twenty one trials of acupuncture for OA were analyzed. Based on the results of this review the following factors might contribute to optimal results from acupuncture treatment. 1) Usage of $ST_{35}$, $GB_{34$, $EX_{32}$, $ST_{36}$ and $SP_9$ acupuncture points. 2) More than four acupuncture points should be used. 3) More than 15 minutes of needle retention time. 4) Needle length-40mm and diameter-0.30mm 5) Usage of EA 6) more than 10 times treatment 7) Treatment frequency of more than once a week, 8) Treatment duration longer than 6 to 8 weeks. Conclusions : High quality clinical trials of Acupuncture for OA is still in lack. Future investigators must concentrate their attentions on the quality of acupuncture treatment itself used in the trials as well as the methodological quality of trials.

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Water Quality Changes in Wastewater Effluent from the Unsaturated and Saturated Soil Aquifer Treatment(SAT) Columns Simulating Shallow Aquifer (얕은 불포화 및 포화 대수층을 모사한 SAT 토양칼럼에서의 하수처리장 방류수 처리 수질 변화)

  • Cha Woo-Suk;Kim Jung-Woo;Choi Hee-Chul;Won Jong-Ho;Kim In-Soo;Cho Jae-Weon
    • Journal of Soil and Groundwater Environment
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    • v.10 no.5
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    • pp.18-24
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    • 2005
  • Water quality changes of wastewater effluent in the shallow aquifier condition was investigated using laboratory unsaturated and saturated SAT columns for over five months. Average DOC removal was 31.9% in the unsaturated SAT column whereas no removal occurred in the saturated SAT column. Under the shallow aquifer condition, nitrification was not completed in the unsaturated SAT column, releasing residual ammonium nitrogen into the saturated SAT column. Short retention time (one day) in the shallow unsaturated SAT column rendered DO of about 2 mg/L to the influent of the saturated SAT column. Phosphate was not removed at all in the unsaturated SAT column while complete removal was achieved in the saturated column. Consequently, organic and inorganic compounds were removed under the shallow aquifer condition as effectively as was in deep aquifer, except for the release of ammonium and relatively high DO into the saturated SAT column.

Effect of Operational Parameters on the Ammonia Stripping (암모니아 스트리핑에 미치는 운전인자의 영향)

  • Seo, Jeong-Beom;An, Kwang-Ho
    • Journal of Korean Society of Environmental Engineers
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    • v.28 no.9
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    • pp.935-939
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    • 2006
  • The biological nutrient removal from domestic wastewater with low C/N ratio is difficult. Therefore, this study was performed to examine effect of operational parameters such as air supply, hydraulic retention time, pH on the nitrogen removal by ammonia stripping and to increase influent C/N ratio without required carbon source. The ammonia stripping system used for the bench-scale experiment in laboratory had a dimension of 15 cm diameter and 150 cm height. The ammonia stripping reactors were classified into two types, type AS I and type AS II, according to there using or not media. Results of the research showed that the T-N removal efficiency of AS I using plastic media is slightly higher than AS II without media. In experimental condition of air supply 30 L/min and pH 12.5, T-N removal efficiencies increased as HRT of ammonia stripping reactor became longer from 8 hr to 36 hr. In experimental condition of HRT 36 hr, it was also found that the T-N removal efficiencies improved through increase of air supply. On the other hand, C/N ratio of wastewater was increased from average 3.9 to 5.4 by ammonia stripping.