• 한국보육지원학회지
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• 제11권1호
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• pp.153-171
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• 2015

본 연구는 유아의 내적표상 유형에 따라 가정에서의 코티솔 분비 패턴이 어떠한지를 탐색해보고자 하였다. 이를 위해 40명의 유아를 대상으로 이야기 완성과제(MacArthur Story Stem Battery, Breth erton et al. 1990)를 실시하였고, 가정에서 유아의 타액을 채취하여 수집하였다. 수집된 자료는 기술통계, 군집분석을 통해 분석하였다. 분석결과 유아의 내적표상 유형은 불안유형, 제한유형, 비조절된 공격유형, 회피유형, 친사회유형의 5개 유형으로 나타났으며, 유아의 가정에서의 코티솔 분비 패턴은 오전에 코티솔 분비가 많고 오후로 갈수록 떨어지는 패턴으로 나타났다. 또한 내적표상 유형에 따라 분비패턴이 다르게 나타났다. 이러한 결과를 통해 볼 때 유아의 내적 표상이 일상적 스트레스 상황과 부모와의 상호작용시에 유아의 반응과 스트레스 호르몬의 활성화 정도에 영향을 미칠 가능성이 있음을 조심스레 예측할 수 있다.

• Molecular & Cellular Toxicology
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• 제2권4호
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• pp.273-278
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• 2006

95 squamous cell lung carcinoma samples (normal tissue: 40 samples, tumor: 55 samples) were analyzed with 8 K cDNA microarray. 1-way ANOVA test was employed to select differentially expressed genes in tumor with FDR<0.01. Among the selected 1,655 genes, final 212 genes were chosen according to the expression fold change and used for following analysis. The expression of up-regulated 64 genes was verified with Reverse Transcription PCR and 10 genes were identified as candidates for SCC markers. In our opinion, those candidates can be exploited as diagnostic or therapeutic purposes. Gene Ontology (GO) based analysis was performed using those 212 genes, and following categories were revealed as significant biological processes: Immune response (GO: 0006955), antigen processing (GO: 0030333), inflammatory response (GO: 0006954), Cell adhesion (GO: 0007155), and Epidermis differentiation (GO: 0008544). Gene set enrichment analysis (GSEA) also carried out on overall gene expression profile with 522 functional gene sets. Glycolysis, cell cycle, K-ras and amino acid biosynthesis related gene sets were most distinguished. These results are consistent with the known characteristics of SCC and may be interconnected to rapid cell proliferation. However, the unexpected results from ERK activation in squamous cell carcinoma gripped our attention, and further studies are under progress.

• 한국정보통신학회논문지
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• 제20권9호
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• pp.1799-1807
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• 2016

본 논문에서는 기존의 가입자가 직접 전력량을 조절하는 수동수요반응과는 달리 정해진 시간에 자동적으로 전력량 소모를 줄이는 자동수요반응 시스템을 제안하였다. 제안된 시스템은 SEP 2.0을 기반으로 동작하며 수요반응 관리 프로그램과 수요반응 서버, 수요반응 클라이언트로 구성된다. 수요반응 관리 프로그램은 가입자에게 전력사용현황을 알려주고 관리자에게는 수요반응 이벤트를 생성 및 취소할 수 있게 한다. 수요반응 서버는 수요반응 관리 프로그램에서 수신한 수요반응 이벤트를 SEP 2.0을 통해 수요반응 클라이언트로 전송하고 수요반응 클라이언트가 주기적으로 전송하는 미터링 데이터를 데이터베이스에 저장한다. 그리고 수요반응 클라이언트는 수신한 수요반응 이벤트에서 수요반응 이벤트 시작시간과 지속시간, 감소레벨을 추출한 뒤, 특정 기간 동안 전력소모를 감소시킨다.

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2004년도 제29회 추계학술대회 발표논문집
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• pp.36-38
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• 2004

The detector size effect due to the spatial response of defectors is one critical source of inaccuracy in clinical dosimetry and has been a subject of numerous studies. Conventionally, the detector response kernel contains all of the influence that the detector size has on the measured beam profile. Various analytic models for this kernel have been proposed and studied in theoretical and experimental works. Here, we use a method to determine detector response kernel simply by using Monte Carlo simulation and convolution theory. Based on this numerical method and DOSIMETER, an EGS4 Monte Carlo code, the detector response for a Farmer type ion chamber embedded in water phantom is obtained. There exists characteristic difference in the simulated chamber readings between one with carbon graphite wall and the other with Acrylic wail. Using the obtained response and the convolution theory, we are planning to derive the detector response kernel numerically and remove detector size effect from measurements for 6MV, 10${\times}$l0cm2 and 0.5${\times}$10 cm2 photon beam.

• International Journal of Naval Architecture and Ocean Engineering
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• 제11권2호
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• pp.923-938
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• 2019

Surge motion of top-end platform induced by periodic wave makes marine flexible riser encounter equivalent sheared-oscillatory flow, under which the Vortex-induced Vibration (VIV) response will be more complicated than pure sheared flow or oscillatory flow cases. Based on a time domain force-decomposition model, the VIV response characteristics under sheared-oscillatory flows are investigated numerically in this paper. Firstly, the adopted numerical model is validated well against laboratory experiments under sheared flow and oscillatory flow. Then, 20 sheared-oscillatory flow cases with different oscillation periods and top maximum current velocities are designed and simulated. Under long and short oscillation period cases, the structural response presents several similar features owing to the instantaneous sheared flow profile at each moment, but it also has some different patterns because of the differently varying flow field. Finally, the effects and essential mechanism of oscillation period and top maximum current velocity on VIV response are discussed systematically.

• 대한안전경영과학회지
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• 제19권1호
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• pp.1-8
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• 2017

The current study aims to propose a reorganization plan for the national emergency management system to improve the current organizational structure for responding to national disasters and emergency situations. As a theoretical framework, the current study identified four key elements of successful disaster response systems: responsiveness, controllability, expertise, and devotedness. On the basis of the four key elements of disaster response systems, this study critically reviewed the current state of the organizational structure of the Korean national emergency response system by discussing the issues inherent in the current structure and by doing a comparative analysis of two high-profile national disaster cases-the Sewol ferry disaster in 2014 and the Gwangsan Rescue of buried people in 2013. Then, this study proposed the reorganization plan for the national disaster response system in which the NEMA is under direct control of the Prime Minister of Korea. It coordinates and controls the related government departments, such as the police, maritime police, and military during the national disaster and emergency situation. This study also proposed a reorganizational plan for the regional disaster response system in Korea. Finally, it was suggested that the status of firefighters should be elevated to the national public servant level in order to achieve organizational efficiency and solve existing problems that come from the current separated systems.

• Coupled systems mechanics
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• 제3권2호
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• pp.147-170
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• 2014

In the recent times, dimensions of heavy load carrying vehicle have changed significantly incorporating structural flexibility in vehicle body. The present paper outlines a procedure for the estimation of bridge response statistics considering structural bending modes of the vehicle. Bridge deck roughness has been considered to be non homogeneous random process in space. Influence of pre cambering of bridge surface and settlement of approach slab on the dynamic behavior of the bridge has been studied. A parametric study considering vehicle axle spacing, mass, speed, vehicle flexibility, deck unevenness and eccentricity of vehicle path have been conducted. Dynamic amplification factor (DAF) of the bridge response has been obtained for several of combination of bridge-vehicle parameters. The present study reveals that flexible modes of vehicle can reduce dynamic response of the bridge to the extent of 30-37% of that caused by rigid vehicle model. However, sudden change in the bridge surface profile leads to significant amount of increment in the bridge dynamic response even if flexible bending modes remain active. The eccentricity of vehicle path and flexural/torsional rigidity ratios plays a significant role in dynamic amplification of bridge response.

• Biotechnology and Bioprocess Engineering:BBE
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• 제10권4호
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• pp.304-308
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• 2005

The response of IPTG induction was investigated through the monitoring of the alkali consumption rate and buffer capacity during the cultivation of recombinant E. coli BL21 (DE3) harboring the plasmid pRSET-LacZ under the control of lac promoter. The rate of alkali consumption increased along with cell growth, but declined suddenly after approximately 0.2 h of IPTG induction. The buffer capacity also declined after 0.9 h of IPTG induction. The profile of buffer capacity seems to correlate with the level of acetate production. The IPTG response was monitored only when introduced into the mid-exponential phase of bacterial cell growth. The minimum concentration of IPTG for induction, which was found out to be 0.1 mM, can also be monitored on-line and in-situ. Therefore, the on-line monitoring of alkali consumption rate and buffer capacity can be an indicator of the metabolic shift initiated by IPTG supplement, as well as for the physiological state of cell growth.

• 대한미생물학회지
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• 제9권1호
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• pp.41-45
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• 1974

On day 2 after treatment of Lewis rat with 25mg of hydrocortisone, the cell number in the thymus was reduced to less than 10% of the matched control. By day 12 after hydrocortisone treatment the thymic cell population was recovered almost its original value and on day 24 after treatment the number of thymocytes was equivalent to that of normal thymocytes. The density distribution profile of hydrocortisone treated rats as compared with normal rats showed a marked decrease in the denser fraction D while the lighter fractions. (A plus B, and C) showed a considerable proportional increase. The proportion of dead cells in thymus suspension from hydrocortisone treated rats was higher than that from their normal counterparts. On separation, the dead cells accumulated selectively in the pellet and A fraction. The response of the thymocytes from hydrocortisone treated rats to PHA was increased compared to that from normal rats. Among the subpopulations, D fraction, which was relatively unresponsive in normal rats, showed a marked increase in PHA response and C fraction showed some increase in the response.

• 조명전기설비학회논문지
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• 제24권3호
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• pp.20-26
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• 2010

In ultrashort-pulse reflectometry (USPR), a chirped waveform transformed from the USPR source impulse signal via waveguide makes it possible to employ millimeter-wave mixers for the frequency up-conversion process. Consequently, the frequency bandwidth of the USPR system is sufficiently wide to cover a large portion of the electron density profile of the plasma. Some physical aspects of the chirped waveform, such as maximum amplitude and length, are critical factors to determine the performance of the system. In this paper, the propagation of the USPR impulse signal through a rectangular waveguide is numerically studied to derive the chirped waveform using the impulse response of the waveguide. The results of numerical computation show that the chirped waveform significantly depends on the waveguide cutoff frequency as well as the waveguide length.