• Title/Summary/Keyword: residual time

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Uterine Sarcoma: Clinical Presentation, Treatment and Survival Outcomes in Thailand

  • Potikul, Chalermrat;Tangjitgamol, Siriwan;Khunnarong, Jakkapan;Srijaipracharoen, Sunamchok;Thavaramara, Thaovalai;Pataradool, Kamol
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.4
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    • pp.1759-1767
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    • 2016
  • Background: Uterine sarcoma is a group of rare gynecologic tumors with various natures, and different lines of treatment. Most have a poor treatment outcome. This study targeted clinical characteristics, treatment, overall survival (OS), progression-free survival (PFS), and prognostic factors in uterine sarcoma patients in one tertiary center for cancer care. Materials and Methods: Uterine sarcoma patients who were treated at the Department of Obstetrics and Gynecology, Faculty of Medicine Vajira Hospital between January 1994 and December 2014 were identified. Clinico-pathological data were analyzed. Prognostic outcomes were examined by Kaplan-Meier curves and Cox regression analysis. Results: We identified 46 uterine sarcoma patients: 25 carcinosarcoma (CS) (54.3%), 15 leiomyosarcoma (LMS) (32.6%), and 6 undifferentiated uterine sarcoma (UUS) (13.1%) cases. Mean age was $54.0{\pm}11.9years$ (range 25-82 years). Abnormal uterine bleeding was the most common presenting symptom (63.0%). Among 33 patients (71.7%) who had pre-operative tissue collected, diagnosis of malignancy was correct in 29 (87.9%). All patients received primary surgery and retroperitoneal lymph nodes were resected in 34 (73.9%). After surgery, 5 (10.9%) had gross residual tumors. Stage I disease was most commonly found (56.5%). Adjuvant treatment was given to 27 (58.7%), most commonly chemotherapy. After a median follow-up of 16.0 months (range 0.8-187.4 months), recurrence was encountered in 22 patients (47.8%). Median time to recurrence was 5.8 months (range1.0-105.5 months). Distant metastasis was more common than local or locoregional failure. The 2-year PFS was 45.2% (95% confidence interval [CI], 30.6%-59.7%) and the 2-year OS was 48.3% (95% CI, 33.3%-60.7%). Multivariable analyses found residual disease after surgery as a significant factor only for PFS. Conclusions: Uterine sarcoma is a rare tumor entity. Even with multimodalities of treatment, the prognosis is still poor. Successful cytoreductive surgery is a key factor for a good survival outcome.

Growth of Graphene Films from Solid-state Carbon Sources

  • Kwak, Jinsung;Kwon, Tae-Yang;Chu, Jae Hwan;Choi, Jae-Kyung;Lee, Mi-Sun;Kim, Sung Youb;Shin, Hyung-Joon;Park, Kibog;Park, Jang-Ung;Kwon, Soon-Yong
    • Proceedings of the Korean Vacuum Society Conference
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    • 2014.02a
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    • pp.181.2-181.2
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    • 2014
  • A single-layer graphene has been uniformly grown on a Cu surface at elevated temperatures by thermally processing a poly (methyl methacrylate) (PMMA) film in a rapid thermal annealing (RTA) system under vacuum. The detailed chemistry of the transition from solid-state carbon to graphene on the catalytic Cu surface was investigated by performing in-situ residual gas analysis while PMMA/Cu-foil samples being heated, in conjunction with interrupted growth studies to reconstruct ex-situ the heating process. We found that the gas species of mass/charge (m/e) ratio of 15 ($CH_3{^+}$) was mainly originated from the thermal decomposition of PMMA, indicating that the formation of graphene occurs with hydrocarbon molecules vaporized from PMMA, such as methane and/or methyl radicals, as precursors rather than by the direct graphitization of solid-state carbon. We also found that the temperature for dominantly vaporizing hydrocarbon molecules from PMMA and the length of time, the gaseous hydrocarbon atmosphere is maintained, are dependent on both the heating temperature profile and the amount of a solid carbon feedstock. From those results, we strongly suggest that the heating rate and the amount of solid carbon are the dominant factors to determine the crystalline quality of the resulting graphene film. Under optimal growth conditions, the PMMA-derived graphene was found to have a carrier (hole) mobility as high as ${\sim}2,700cm^2V^{-1}s^{-1}$ at room temperature, which is superior to common graphene converted from solid carbon.

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An Experimental Study on the Curing Method and PP Fiber Mixing Ratio on Spalling Resistance of High Strength Concrete (양생요인 및 PP 섬유 혼입율 변화에 따른 고강도 콘크리트의 폭렬특성)

  • Han, Cheon-Goo;Kim, Won-Ki
    • Journal of the Korea Institute of Building Construction
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    • v.9 no.6
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    • pp.113-119
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    • 2009
  • This study is to investigate the fundamental and fireproof qualities of high strength concrete corresponding to changes in the curing factors and the PP fiber ratio. The results were as follows. For the fundamental characteristics of concrete, the fluidity was reduced in proportion to the increase in the PP fiber ratio. The compressive strength was somewhat reduced according to an increase in the PP fiber ratio. However, it had the high strength scope of more than 60 MPa at 7 days and of more than 90 MPa at 28 days. On the spalling mechanism followed by changes of the water content ratio, spalling was prevented in all combinations, except the specimen without PP fiber and subjected to 3.0% of moisture contents. When spalling was prevented at that time, the residual compressive strength ratio was 22%~41% and the mass reduction ratio was 5%~7%, which was relatively favorable. As the spalling mechanism corresponds to changes in the curing method, spalling was prevented in concrete with a PP fiber mixing ratio of more than 0.05% in the event of standard curing, and in concrete with a PP fiber mixing ratio of more than 0.10% in the case of steam curing and autoclave curing. In these cases, when spalling was prevented, the residual compressive strength ratio was 23~42% and the mass reduction ratio was 7~11%. In these results, the ease of spalling prevention in high strength concrete was inversely proportional to the water content ratio. Depending on the curing method, spalling was prevented in concrete with over 0.05% PP fiber with standard curing and in concrete with over 0.1% PP fiber with steam curing and autoclave curing.

Transform Skip Mode Fast Decision Method for HEVC Encoding (HEVC 부호화를 위한 변환생략 모드 고속 선택 방법)

  • Yang, Seungha;Shim, Hiuk Jae;Lee, Dahee;Jeon, Byeungwoo
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.39A no.4
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    • pp.172-179
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    • 2014
  • HEVC (High Efficiency Video Coding) fine-tuned many existing coding tools and adopted also many new coding techniques. As a result, HEVC has accomplished about 2 times of compression efficiency enhancement compared to the existing video coding standard of H.264/AVC. One of the newly adopted tools in HEVC is the transform skip scheme which performs quantization without transform. This technique improves coding efficiency especially with computer-generated images. However, the unavailability of global or local properties of general video signals demands encoder to decide whether performing transform or not for each TU (Transform Unit). The necessity of computing rate-distortion costs for this decision is one reason to increase encoder complexity. In this paper, a fast transform skip mode decision method is proposed, which is based on the fast decision of rate-distortion cost calculation for transform skip mode, by considering frequency characteristics of residual signal. The proposed method can reduce $4{\times}4$ TU encoding time by about 27.1% with only about 0.03% consequential decrement in BDBR.

Extraction of Expansion Length for Expansion Jiont Bridge using Imagery (영상을 이용한 교량 신축이음부의 신축량 추출)

  • Seo, Dong-Ju;Kim, Ga-Ya
    • Journal of the Korean Association of Geographic Information Studies
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    • v.11 no.4
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    • pp.139-149
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    • 2008
  • A load effect by vehicles running on a road and an increase of traffic is distinguished as a serious issue in the level of bridges' maintenance and management since it causes a quick damage of bridges. The expansion joint is the most important since it makes vehicles' traveling amicable and stress or additional load harmful to molding patterns minimized. However, it is very difficult to measure its expansion length since vehicles continue to pass on the expansion joint. Therefore, the study could see that it was possible to carry out a qualitative and quantitative maintenance and management if its expansion length is extracted with images. The study could acquire three dimensional coordinates of expansion joints with images. As the results of calculating RMSE of check point residual at 32 points in A area and at 28 points in B area, both A and B areas had very good results of RMSEsms 0.829mm~1.680mm. As the results of analyzing expansion length and immediate value extracted by images, the study analyzed that RMSE of A area was 0.64mm and RMSE of B area was 0.28. The average residual of A area was 0.60% and the average rresidual of B area was 0.27%. Therefore, it is judged that it is more scientific and efficient than the past to measure expansion length with images at the time of repairing and managing bridges in the future.

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Persistence of Chlorfenapyr in Paprika Leaf and Its Residual Biological Activity to Two Spotted Spider Mite, Tetranychus urticae (파프리카 잎 중 Chlorfenapyr의 잔류량 변화와 점박이응애에 대한 잔효 생물 활성)

  • Cho, Kyu-Song;Lee, So-Jung;Lee, Dong-Yeol;Kim, Yeong-Jin;Kim, Kyoung-Youl;Chung, Bu-Keun;Kang, Kyu-Young
    • The Korean Journal of Pesticide Science
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    • v.15 no.3
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    • pp.317-322
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    • 2011
  • A comparative experiment was conducted to investigate the persistence of chlorfenapyr residue and its biological activity to two spotted spider mite, Tetranychus urticae, after treatment of chlorfenapyr suspension concentrate (10% SC) on paprika plants at recommended (2000 times dilution) and double dosage. Biological half-lives of chlorpfenapyr were estimated as 8 and 5 days in leaves and fruits of paprika plants, respectively. While initial deposits of chlorfenapyr residues in leaves at recommended and double dosages were 22.22 and 37.75 ${\mu}g\;g^{-1}$ at the time of application, its residue decreased to 1.56 ${\mu}g\;g^{-1}$ and 3.62 ${\mu}g\;g^{-1}$ at 29 days after treatment, respectively. Residual biological activity of chlorfenapyr SC to T. urticae at recommended dosage lasted for 7 or 15 days on the basis of 24 or 48-hrs mortality test assayed with feeding on excised leaf chlorfenapyr-treated. The control efficacy to the mite showed a good agreement with the persistence of chlorfenapyr residues in leaves.

Residual Characteristics of Bifenthrin and Imidacloprid in Squash (Bifenthrin과 Imidacloprid의 호박 중 관류특성)

  • Lee, Eun-Young;Noh, Hyun-Ho;Park, Young-Soon;Kang, Kyung-Won;Lee, Kwang-Hun;Lee, Jae-Yun;Park, Hyo-Kyung;Yun, Sang-Soon;Jin, Chung-Woo;Han, Sang-Kuk;Kyung, Kee-Sung
    • The Korean Journal of Pesticide Science
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    • v.13 no.2
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    • pp.79-86
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    • 2009
  • In order to elucidate the residual characteristics of the insecticides, bifenthrin and imidacloprid, the pesticides were sprayed onto the squash and their residues were analyzed with GC-ECD and HPLC. Detection limits of the pesticides were $0.005\;mg;kg^{-1}$ and recoveries of bifenthrin and imidacloprid in squash were from 100.87 to 104.31 and from 79.71 to 92.54%, respectively. Half-lives of bifenthrin and imidacloprid in squash were from 1.8 to 2.9 and from 1.5 to 2.5 days, respectively. Initial concentration of bifenthrin and imidacloprid sprayed at the recommended rate and double rate of recommendation were less than their MRLs. And also, residueal concentrations of the pesticides were rapidly decreased in squash with time. At harvest, estimated daily intakes (EDIs) of the pesticides were less than 0.6% of their acceptable daily intakes (ADIs).

Identification of bacterial agents causing mastitis in dairy cattle and observation of residual changes of sulfadimethoxine in serum and milk of the cattle after administration of sulfadimethoxine sodium (유방염 우에서 원인균분리 및 sulfadimethoxine sodium 투여 후 혈청 및 유즙내 잔류량 추이)

  • 조민희;도재철;송희종;정종식
    • Korean Journal of Veterinary Service
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    • v.24 no.1
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    • pp.31-41
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    • 2001
  • This study was carried out to identify causative agents from california mastitis test(CMT) positive mastitic milk, and to examine the antimicrobial susceptibility of 50 heads in Seongju and Chilgok area of Gyeongbuk province. Sulfadimethoxine sodium(SMS) was intramuscularly administered once to four mastitis Infected dairy cattle at the rate of 10mg/kg body weight. After injection of SMS, the depletion rate of serum and milk from the cattle were periodically measured for five days. The CMT positive number from 50 heads showed 46% and that of 200 quarters was 47(23.5%). From 39 quarters of 47 heads 39 different microorganisms were identified. These organisms were classified into 12 species : Staphylococcus aureus 8(20.5%), Sta hemolyticus 6(15.4%), Streptococcus bovis 4(10.3%), Sta hyicus 3(7.7%), Sta epidemidis. Sta xylosus, Sta sciuri 2(5.1%), Str agalactiae 2(5.1%), Escherichia coli(10.3%), three Enterobacter cloacae(7.7%), two Ent aerogenes(5.1%) and one Salmonella spp(2.6%). As the results of antibiotic susceptibility test, gentamicin(Gm, 11 species 27 strains, 69.5%), cephalotin(Cf, 9 species 24 strains, 61.5%), sulfamethoxazole(Stx, 8 species 14 strains, 43.6%), tetracycline(Tc, 8 species 14 strains, 35.9%), and streptomycin(Sm), lincomycin(Lm), cefoperazon(Cp) and penicillin(Pc) have a highly resistance(7.7% ~5.1%). However, carbenicillin (Cb), amikacin(Ah) have no susceptible for all drugs. The mean residual concentration of SMS in serum according to the time lapsed were showed 33.964 $\pm$ 4.435ppm at the 4 hours after intramuscularly injection(AII). It was significantly(p<.05) decreased to 6.596 $\pm$ 3.402, 0.217 $\pm$ 0.119 and 0.005 $\pm$ 0.004ppm at the 1st, 3rd and 5th day AII. The mean concentration of SMS in milk was significantly(p<.05) decreased from 0.920 $\pm$ 0.42ppm to 0.084 $\pm$ 0.016ppm between 8 hours and 1 day AII. As the results of this experiments, sulfadimethoxine was residued at the level of no less than 0.01ppm in milk on the 2nd day AII. Thus, this results would be able to be used the basic index for prevention of sulfonamides residue in milk after treatment of dairy mastitis.

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Comparison of residue patterns between foliar application and drenching in export strawberry (경엽 및 관주 처리에 따른 딸기 중 침투성 농약 잔류패턴 비교)

  • Lee, Hyo-Sub;Hong, Su-Myeong;Kwon, Hye-Young;Kim, Dan-bi;Moon, Byeong-Chul
    • Journal of Applied Biological Chemistry
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    • v.60 no.4
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    • pp.313-319
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    • 2017
  • Strawberries are one of the main commodities in Korea and have been exported over 30 million dollar. And the safety has recently become an important issue in the agro-trade, pesticide residue is most important matter of safe agricultural products. As strawberries can be cultivated using elevated production system, so it is possible to use the drenching. When spraying the pesticides, the use of drenching can be lower amount of residual than using foliar treatment. In this study, time sequential residual amount of pesticides were compared between drenching and foliar application in strawberries. Pesticides were treated with the standard and double dosage and samples were collected at 0, 3, 6, 9, 13, 16 and 21 day and analyzed by LC and LC-MS/MS after liquid-liquid extraction and QuEChERS. Two pesticides were detected less than 1 mg/kg in all samples for drenching treatment. Carbendazim residues in drenching treatment were 5 to 25 times lower than foliar application. And azoxystrobin was not detected in strawberries of drenching treatment.

Accelerated compression of sub-images by use of effective motion estimation and difference image methods in integral imaging (집적영상에서 효율적인 물체움직임 추정 및 차 영상 기법을 이용한 서브영상의 고속 압축)

  • Lee, Hyoung-Woo;Kim, Eun-Soo
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.16 no.12
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    • pp.2762-2770
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    • 2012
  • In this paper, we propose a novel approach to effectively compress the sub-images transformed from the picked-up elemental images in integral imaging, in which motion vectors of the object in each sub-image are fast and accurately estimated and compensated by combined use of MSE(mean square error)-based TSS(tree-step search) and FS(full search) schemes. This is, the possible object areas in each sub-image are searched by using the fast TSS algorithm in advance, then the these selected object areas are fully searched with the accurate FS algorithm. Furthermore, the sub-images in which all object's motion vectors are compensated, are transformed into the residual images by using the difference image method and finally compressed with the MPEG-4 algorithm. Experimental results reveal that the proposed method shows 214% improvement in the compression time per each image frame compared to that of the conventional method while keeping the same compression ratio with the conventional method. These successful results confirm the feasibility of the proposed method in the practical application.