• Particle and aerosol research
• /
• v.11 no.2
• /
• pp.29-36
• /
• 2015

The purpose of this research is to find out the collection property of nanoparticle in diffusion filter to know particle size dispersion of nanomaterial using inertial force and principle of Brownian diffusion motion. We used inertial filters which are two different type and diffusion filters made by various kinds of Wiremesh and the different pieces of filter to compare with particle size distribution using NaCl particles. Finally, We made a conclusion as follows : (1) the bigger available charging volume is and the larger specific surface area of inertial filter is, the better collection efficiency is. (2) The higher wire-mesh number of filter is, the more collection efficiency of small particle is increasing because the wire of the higher Wiremesh number filter is thinner and denser. (3) The more pieces of wire-mesh filter, the more collection efficiency is increasing because it makes the residence time longer.

• Biotechnology and Bioprocess Engineering:BBE
• /
• v.11 no.5
• /
• pp.466-469
• /
• 2006

The bed stability of Streamline DEAE (p = 1.2 g/mL) in a 20mm (i.d.) glass expanded bed contactor, and its performance on the recovery of glucose 6-phosphate dehydrogenase (G6PDH) from unclarified yeast homogenate were investigated. A residence time distribution study showed that a stable expanded bed was achieved. The theoretical plate and Bodenstein numbers determined were 25 and 53, respectively. A recovery yield of 87% and purification factor of 4.1 were achieved in the operation using 5% (w/v) biomass concentration feedstock. The performance of the anion exchange EBAC was still considerable good at a biomass concentration as high as 15% (w/v).

• Water for future
• /
• v.27 no.2
• /
• pp.129-137
• /
• 1994

The surface hydrology of large land areas is susceptible to several preferred stable states with transitions between stable states induced y stochastic fluctuation. This comes about due to the close coupling of land surface and atmospheric interaction. An interesting and important issue is the duration of residence in each mode. Mean transtion times between the stable modes are analyzed for different model parameters or climatic types. In an example situation of this differential equation exhibits a bimodal probability distribution of soil moisture states. Uncertainty analysis regarding the model parameters is performed using a Monte-Carlo simulation method. The method developed in this research may reveal some important characteristics of soil moisture or precipitation over a large area, in particular, those relating to abrupt changes in soil moisture or precipitation having extremely variable duration.

• Applied Chemistry for Engineering
• /
• v.8 no.6
• /
• pp.901-906
• /
• 1997

Ultrafine silicon dioxide($SiO_2$) powder was prepared from tetraethylorthosilicate(TEOS) by the gas-phase reaction. The effects of reaction temperature, flow rate of gas, TEOS concentration, and preheating temperature of reactants on the particle size were investigated. As the reaction temperature increased, average particle size of the silicone dioxide powder became smaller. Smaller particles were also obtained with decreasing the residence time of reactants in the reaction zone. Larger particles having narrow size distribution were produced with the high concentrations of the reactants. The effect of the preheating temperature was not considerable on the average particle size. The range of average particle size was from 30 nm to 58 nm depending on experimental conditions.

• Journal of Pharmaceutical Investigation
• /
• v.38 no.6
• /
• pp.399-403
• /
• 2008

The aim of this study was to evaluate the difference of analytical methods for the pharmacokinetic study of bromosulfophthalein (BSP), an indicator of hepatobiliary function. The plasma and bile concentrations of BSP after intravenous administration were measured according to custom UV spectroscopy and HPLC, respectively. Plasma concentration of BSP measured by UV spectroscopy was similar to that measured by HPLC. There was no significant difference in the distribution volume, total body clearance, area under the curve and mean residence time of BSP between different analytical method groups. However, bile concentration of BSP measured by UV spectroscopy was overestimated compared with concentration measured by HPLC method. Biliary clearance of BSP obtained from UV spectroscopy method was almost 3 times higher than that obtained from HPLC method. Thus, a feasibility of UV spectroscopy method for high throughput pharmacokinetic evaluation of BSP was limited to the study based on the plasma concentration of BSP, not bile concentration.

• Investigative Magnetic Resonance Imaging
• /
• v.2 no.1
• /
• pp.73-82
• /
• 1998

Purpose : A precise NMR technique for measuring the rate of water exchange and cell membrane permeability across the hepatocyte membrane using liver-specific MR contrast agent is described. Materials and Methods : The rat hepatocytes isolated by perfusion of the livers were used for the NMR measurements. All experiments were performed on an IBM field cycling relaxometer operating from 0.02MHz to 60 MHz proton Larmor frequency. spin-echo pulse sequence was empolyed to measure spin-lattice relaxation time, T1. The continuous distribution analysis of water proton T1 data from rat hepatocytes containing low concentrations of the liver specific contrast agent, Gd-EOB-DTPA, modeled by a general two compartment exchange model. Results : The mean residence time of water molecule inside the hepatocyte was approximately 250 msec. The lower limit for the permeability of the hepatocyte membrane was $(1.3{\pm}0.1){\;}{\times}{\;}10^{-3}cm/sec$. The CONTIN analysis, which seeks the natural distribution of relaxation times, reveals direct evidence of the effect of diffusive exchange. the diffusive water exchange is not small in the intracellular space in the case of hepatocytes. Conclusions : Gd-EOB-DTPA, when combined with continuous distribution analysis, provides a robust method to study water exchange and membrane permeability in hepatocytes. Water exchange in hepatocyte is much slower thatn that in red blood cells. Therefore, tissue-specific contrast agent may be used as a functional agent to give physiological information such as cell membrane permeability.

• Journal of the Korea Organic Resources Recycling Association
• /
• v.12 no.2
• /
• pp.52-60
• /
• 2004

The basic approach to sewage sludge is organic waste minimization, promotion of energy recovery; volume and weight reduction by final treatment, and environmentally final disposal of natural circulation. Dry and pyrolysis of maize was experimentally investigated in full-scale rotary kiln in semi-continuous operation. The operational parameters varied are the operating temperature $160{\sim}175^{\circ}C$ of dry and $450{\sim}800^{\circ}C$ of pyrolysis, the solids residence time 9 min for pyrolysis. Important parameters studied include the running time, water content of sewage sludge, solids amount of sewage sludge(TS%) by the varied temperature. Also, with the increasing of temperature, how the yield of oil and char product change was observed, and the distribution of gas production components was observed. The gas of $C_1{\sim}C_3$ yield increased and oil of $C_4{\sim}C_6$ yield decreased along with pyrolysis temperature of $670^{\circ}C$ by the run time of 9 min.

• Journal of Radiation Protection and Research
• /
• v.32 no.3
• /
• pp.117-122
• /
• 2007

The hydrodynamic behaviors of the clarifier with an interior baffle in a wastewater treatment plant was investigated by using a radiotracer $^{99m}Tc$(30 40 mCi) to verify the results of CFD(computational fluid dynamics) modelling in the previous study. The clarifier model was manufactured with consideration to the hydraulic similarity(1/21) of a real plant($L{\times}W{\times}H:2.6{\times}0.4{\times}0.2m$). By installation of an interior baffle to the clarifier, the strong density current at the bottom of the clarifier decreased substantially and increased the area of sludge settling zone, which were visualized successfully from the radiotracer experiment. Also the portion of short circuit stream changed from 48 % to 32 % and the mean residence time of sludge decreased from 940 sec to 810 sec, which corresponds to the results of CFD modelling. As a result, it is anticipated that radiotracer technology can be used as an important tool for designing new wastewater treatment plants and verifying their performances after structural modifications.

• The Korean Journal of Nuclear Medicine
• /
• v.29 no.1
• /
• pp.54-60
• /
• 1995

Medical Internal Radiation Dose(MIRD) schema was developed for calculating the absorbed dose from the administered radiopharmaceuticals. With the biological distribution data and the physical properties of the radionuclide we can estimate the absorbed dose by the MIRD schema. For the thyroid cancer patients received $^{131}I$ therapy, the absorbed dose to the bone marrow is the limiting factor to the administered dose, and the duration of admission is deter-mined by the retained activity in the whole body. To monitor the whole body radioactivity, we used Eberline Smart 200 system using ionization chamber as a detector. With the time activity curve of the whole body, total body residence time was obtained. From the ICRP publication 53, the residence times of the source organs, such as kidney, urinary bladder content and stomach, were used to calculate the absorbed doses of the target organs, such as stomach, red marrow, bladder wall and remaineder total body. In 8 thyroid cancer patients with 175 mci of $^{131}I$ administered orally, the mean absorbed dose in the bladder wall was 375.1, in the stomach 285.1, red marrow 25.4 and total body 22.4 rad respectively. For the monitoring of the large administered activity, this method seemed to be quite useful.

• Journal of Korean Society of Environmental Engineers
• /
• v.35 no.2
• /
• pp.101-108
• /
• 2013

Ara Canal is the first artificial canal in Korea that connects the Han River and the Yellow Sea. Due to mixture of waters with different salinity and water quality, complicated hydrodynamic and water quality distributions are expected to occur inside the canal. An integrated hydrodynamic and water quality modeling system was developed using the 3 dimensional hydrodynamic model, EFDC (Environmental Fluid Dynamics Code) and the water quality model WASP (Water Quality Analysis and Simulation Program). According to the modeling results, BOD, TN, TP and Chl-a concentrations inside the canal were lower at the West Gate side than the Han River side since influent concentrations of the West Gate side are significantly lower. Chemical stratification due to salinity difference were more evident at the West Gate side as vertical salinity difference were more pronounced in this area. On the other hand, Chl-a concentrations showed more pronounced vertical distribution at the Han River side as Chl-a concentrations were higher in this area. It was notable that Dissolved Oxygen concentrations can be lower than 2 mg/L occasionally in the middle part of the canal. While major factor affecting DO concentrations in the canal are inflows via both gates, the other important factor was found to be BOD decay in the canal due to extended hydraulic residence time. This study can be used to predict hydrodynamic conditions and water quality in the canal during the year and thus can be helpful in the development of gate operation method of the canal.