• 제목/요약/키워드: reporting bias

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반월상 연골 손상에 대한 수기치료의 효과: 체계적 고찰 및 메타분석 (Efficacy of Manual Therapy for Knee Meniscus Injuries: A Systematic Review and Meta-Analysis)

  • 강석범;박한별;손우석;김영준;우창훈
    • 척추신경추나의학회지
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    • 제17권2호
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    • pp.17-25
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    • 2022
  • Objectives This study aimed to evaluate the efficacy of manual therapy for knee meniscus injuries. Methods We searched seven electronic databases (MEDLINE, Cochrane Library, CAJ, Wanfang, RISS, ScienceON, and OASIS) to collect randomized controlled trials (RCTs) using the keywords "manual therapy OR chuna OR tuina" and "meniscus injury." Results Eleven RCTs were selected based on the inclusion criteria, and all studies were conducted in China. Five studies were meta-analyzed. The systematic review revealed a positive effect of manual therapy for knee meniscus injury. Low risk of selection, attrition, and reporting bias were demonstrated in all studies. Ten studies had a high risk of performance bias. Conclusions The systematic review reported favorable results using manual therapy for knee meniscus injury. However, this study has several limitations because of the high risk of bias. Further clinical studies and reviews with higher levels of evidence are warranted.

건선 환자에서 아시트레틴 치료에 추가한 한방 약욕 효과 : 체계적 문헌 고찰과 메타 분석 (Add-on Effect of Herbal Bath Combined with Acitretin Treatment in Patients with Psoriasis : Systemic Review and Meta-analysis)

  • 전서연;박수진;이지은;김규석
    • 한방안이비인후피부과학회지
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    • 제36권3호
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    • pp.74-98
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    • 2023
  • Objectives : This study aims to evaluate the add-on effect of herbal bath combined with acitretin in patients with psoriasis. Methods : We searched randomized controlled trials(RCTs) reporting the effect of herbal bath and acitretin combined treatment for psoriasis in 10 electronic databases from their inception to January 2023. Study collection, data extraction, and risk of bias assessment were performed by two independent researchers. Data synthesis and risk of bias evaluation was conducted using Revman 5.4. Results : Ten RCTs with 1,008 subjects were included. Herbal bath and acitretin combined treatment group showed higher average total effective rate than acitretin alone group(RR 1.39; 95% CI: 1.15-1.68, P=0.0006, I2 =0%). Herbal bath and additional treatments such as phototherapy(NB-UVB) and oral herbal medicine, combined with acitretin group also showed higher average total effective rate than acitretin alone group(RR 1.81; 95% CI: 1.47-2.22, P<0.00001, I2 =43%). Herbal bath and phototherapy(NB-UVB) combined with acitretin group also showed higher average total effective rate than acitretin alone group(RR 1.51; 95% CI: 1.18-1.93, P=0.0009, I2 =0%). The overall risk of bias of the included studies was unclear or of high risks. Conclusions : This review showed that the add-on of herbal bath combined with acitretin treatment could be more effective than acitretin alone treatment in patients with psoriasis. However, because of few included studies, heterogeneity between studies, and insufficient quality of included studies, further well-designed RCTs are needed to confirm the add-on effect of herbal bath on psoriasis.

국내 물리치료분야에 대한 질적 평가와 근거 수준 및 권고 등급 모형 개발 방안 (Qualitative Assessment and Development of Level of Evidence and Strength of Recommendation Models in the Field of Physical Therapy in Korea)

  • 조성현;이정우
    • 대한통합의학회지
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    • 제11권2호
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    • pp.231-242
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    • 2023
  • Purpose : This study aimed to identify ways to improve the quality of physical therapy research and ultimately review the current situation to improve evidence-based decision-making in physical therapy. Methods : For better evidence-based decision-making in physical therapy, researchers should review the quality assessment of articles in more detail and report their findings for valid and appropriate level of evidence and strength of recommendations. The level of evidence affects how well the findings are derived from well-designed literature. The evaluation of the evidence focuses primarily on the study design and the degree of bias that may compromise the validity of the findings. The final recommendation is based on a combination of the study design and literature quality. To uncover gems of information in each paper, a risk of bias assessment should be performed after the literature has been initially selected. Results : Researchers should consider the complexity of the intervention, appropriate grouping, and calculation of effect sizes for the intervention. Researchers conducting systematic reviews should provide a detailed description of the quality assessment performed and present a detailed analysis of their interpretation of the results. The results of systematic reviews and meta-analyses should be interpreted with caution and include a risk of bias assessment. Guidelines for the level of evidence and strength of recommendations should be developed and utilized more broadly to improve reporting practices in physical therapy. Conclusion : Researchers should be knowledgeable about the strengths and limitations of each study design and methodology. In the future, researchers will also need to improve their ability to critically evaluate their findings, given the potential for their results to influence clinical practice.

인적자원회계정보가 주가예측에 미치는 영향분석 (An Analysis of the Effects of Human Resource Accounting Information on the Prediction of the Price of Common Stock)

  • 오화중
    • 산업경영시스템학회지
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    • 제18권33호
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    • pp.173-183
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    • 1995
  • The Objective of the study was to determine the usefulness of human resource accounting(HRA) information in assisting financial analysis in their investment decisions. The objective achieved by an investigation through which the reporting of HRA, combined with demographic factors that are independent or interactive, affects the decisions of financial analysts regarding the estimation of the market price of a hypothetical company's common stocks. Two kinds of research were conducted to increase the reliability of the study at the same time. Two or three sets of financial statement were prepared. Each consists of balance sheet and income statement. The actual financial statement was modified to exclude personal bias and opinion.

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자궁경부 상피내종양의 환상투열요법 후 한약치료의 효과 : 체계적 문헌고찰 및 메타분석 (Herbal Medicine for Cervical Intraepithelial Neoplasia After Loop Electrosurgical Excision Procedure: A Systematic Review and Meta-Analysis)

  • 이수정;지해리;이혜정;황덕상;이창훈;장준복;이진무
    • 대한한방부인과학회지
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    • 제33권2호
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    • pp.44-62
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    • 2020
  • Objectives: The purpose of this study is to evaluate the effectiveness of herbal medicine for recovery and treatment of cervical intraepithelial neoplasia (CIN) after loop electrosurgical excision procedure (LEEP). Methods: We searched two english, one chinese and four korean database up to November 4, 2019. Randomised controlled trials (RCTs) were eligible. Primary outcome included Human papilloma virus (HPV) clearance rate and the effective ratio of treatment. And vaginal bleeding time and volume, improvement of symptoms, and recovery of wound were regarded as secondary outcomes. The risk of bias was assessed by two independent authors using the Cochrane risk of bias tool. Results: Of 47 screened, 10 RCTs were included. Number of participants per study ranged from 58 to 360. The studies which used HPV clearance rate as primary outcome were considered as low risk of bias. Most of the studies had considerable heterogeneity in terms of type of intervention, comparison and time-points for outcome measurement. Compared to LEEP alone, herbal vaginal suppository combined group showed favorable results for HPV clearance in patients (5 studies, n=627, 95% CI 1.26 to 1.55, I2=75%). And compared to LEEP alone, herbal external application also showed favorable results for HPV clearance in patients (2 studies, n=252, 95% CI 1.19 to 1.61, I2=86%). Three studies reported mild and temporary adverse events, and no serious adverse events were reported. Conclusions: The studies showed that herbal medicine can significantly effective on recovery of CIN after LEEP. However, included studies suffered from incomplete reporting, high or unclear risk of bias and substantial heterogeneity between studies. In the Future, further high-quality RCTs are needed to prove effectiveness of herbal medicine for CIN after LEEP and reduce the risk of bias.

자율 산업보건사업 실시를 위한 전제조건과 개선되어야 할 사항의 중요도에 관한 연구 (Study of requirements and conditions to be improved for voluntary occupational health program in worksite)

  • 송재석;원종욱;손명세;차봉석;노재훈
    • Journal of Preventive Medicine and Public Health
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    • 제30권4호
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    • pp.840-851
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    • 1997
  • To perform voluntary occupational health program in worksites, regulational supports are necessary. The regulational supports include assessment of current occupational health program and appropriate incentives. The purpose of this study is to find out the requirements of voluntary occupational health program and conditions to be improved. Study population was industrial health managers of both industries with less than 300 workers and over 300 workers, and the member of labor union who is responsible for safety and health in worksite. Two different questionnaire were used to find out the requirements and conditions to be improved respectively, The results were; 1. The category which prevalence rate of occupational injuries and occupational disease should be lower than national average was most important in health managers employed in industries over 300 workers and followed by reporting system, education, worksite policy, work environment assessment, protective equipment, consequently. But those employed in industries less than 300 workers showed high importance in prevalence rate of occupational injuries and disease, reporting system, worksite policy, work environment assessment, protective equipment, education, consequently 2. The members of labor union thought that worksite policy was most important and the next is education, reporting system, work environment assessment, protective equipment, prevalence rate of occupational injuries and disease. 3. There were difference in importance of education and worksite policy according to the size of industries. Reporting system, prevalence rate of occupational injuries and disease, and worksite policy had different importance between members of labor union and health managers. 4. In the results of quiestionnaire for conditions to be improved, the most important condition was top manager's willingness except personal protective equipments, and followed by financial support, legal support. The limitations of this study were the problems of representativeness of study population. but voluntary health program should be performed in worksites which have relatively good occupational health system. So, this selection bias could not disrupt our results.

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Quality of Radiomics Research on Brain Metastasis: A Roadmap to Promote Clinical Translation

  • Chae Jung Park;Yae Won Park;Sung Soo Ahn;Dain Kim;Eui Hyun Kim;Seok-Gu Kang;Jong Hee Chang;Se Hoon Kim;Seung-Koo Lee
    • Korean Journal of Radiology
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    • 제23권1호
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    • pp.77-88
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    • 2022
  • Objective: Our study aimed to evaluate the quality of radiomics studies on brain metastases based on the radiomics quality score (RQS), Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis (TRIPOD) checklist, and the Image Biomarker Standardization Initiative (IBSI) guidelines. Materials and Methods: PubMed MEDLINE, and EMBASE were searched for articles on radiomics for evaluating brain metastases, published until February 2021. Of the 572 articles, 29 relevant original research articles were included and evaluated according to the RQS, TRIPOD checklist, and IBSI guidelines. Results: External validation was performed in only three studies (10.3%). The median RQS was 3.0 (range, -6 to 12), with a low basic adherence rate of 50.0%. The adherence rate was low in comparison to the "gold standard" (10.3%), stating the potential clinical utility (10.3%), performing the cut-off analysis (3.4%), reporting calibration statistics (6.9%), and providing open science and data (3.4%). None of the studies involved test-retest or phantom studies, prospective studies, or cost-effectiveness analyses. The overall rate of adherence to the TRIPOD checklist was 60.3% and low for reporting title (3.4%), blind assessment of outcome (0%), description of the handling of missing data (0%), and presentation of the full prediction model (0%). The majority of studies lacked pre-processing steps, with bias-field correction, isovoxel resampling, skull stripping, and gray-level discretization performed in only six (20.7%), nine (31.0%), four (3.8%), and four (13.8%) studies, respectively. Conclusion: The overall scientific and reporting quality of radiomics studies on brain metastases published during the study period was insufficient. Radiomics studies should adhere to the RQS, TRIPOD, and IBSI guidelines to facilitate the translation of radiomics into the clinical field.

TV 미디어 비평의 어제와 오늘: <미디어비평(KBS)> 10년, 내용분석 (Media Criticism on TV for the Last 10 Years: A Content Analysis of )

  • 홍원식;김은정
    • 한국언론정보학보
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    • 제64권
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    • pp.59-84
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    • 2013
  • 국내 방송에서는 유일한 미디어 상호비평 목적의 고정편성 프로그램 KBS <미디어비평>이 방송 10년을 맞았다. 본 연구에서는 <미디어비평>의 지난 10년 간 방송분의 비평대상과 내용, 비평의 근거, 문제의 귀인 방식을 방송 꼭지 단위로 분석하였다. 분석의 목적은 첫째, 메타비평의 형식으로 지난 10년 간 우리 언론의 문제점을 도출하고, 둘째, 경영진의 변화에 따라 실제로 비평의 대상과 비평초점, 프로그램 내용 등에 차이가 있는지를 규명하는 것이었다. 분석 결과, 10년 간 <미디어비평>은 정파적 성향에 기인한 편파보도와 불공정성, 피상적 보도와 받아쓰기 관행 등을 우리 언론의 문제점으로 빈번하게 지적한 것으로 나타났다. 또 정권교체에 따른 경영진의 변화는 비평대상과 초점에도 영향을 미쳐, 방송 초기에는 보수언론을 대상으로 보도의 편파성 불공정성에 대해 주로 문제를 제기한 반면, 경영진 교체 이후에는 언론의 상업성에 기인한 과장?선정성과 정보원에 대한 피상적 받아쓰기에 주목 비평한 것으로 분석되었다.

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환자군 연구(Case series) 및 점검(Audit) 연구의 수행과 보고;저자를 위한 지침서 (Conducting and reporting case series and audits;author guidelines)

  • 김송이;김상우;이향숙;박히준
    • Korean Journal of Acupuncture
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    • 제24권4호
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    • pp.13-24
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    • 2007
  • Objectives : This article aims to give guidance on the conduct and reporting of case series and audits of acupuncture, based on common problems that have arisen in the past. This type of project, and particularly the prospective case series or pre- post-intervention study, may give valuable evidence of the overall effectiveness of acupuncture-for example in different situations and in different conditions- and provides one step in the research pathway before generating an hypothesis. Results & Discussion : The project should be designed with the aim of reducing bias as much as possible. Careful and detailed planning is essential for the project to produce worthwhile results that readers can evaluate and replicate. Ethical issues should be considered and formal approval may be necessary. The patient group should be recruited systematically and baseline data obtained. The treatment given should be systematic and decisions to change or end treatment made explicit. The outcome should be measured in ways that are known to be reliable and valid. Musculoskeletal problems can be evaluated with scales for pain and confirmed by measuring one other symptom such as stiffness or one other aspect such as bothersomeness. Global change scores also provide supporting information, and the MYMOP (Measure Yourself Medical Outcome Profile) measure is popular when patients with different conditions are included. The design of questionnaires for beliefs and attitudes is a specialised area that should not be attempted without expert help. Adverse events should also be recorded. Analysis of the data and the best way of summarising and presenting the results are also discussed.

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박근혜 대통령 탄핵 보도 편향성에 관한 연구 -MBC와 JTBC의 저녁종합뉴스를 중심으로- (Bias in TV News Coverage of President Park's Impeachment -Focusing on MBC and JTBC Evening News-)

  • 김병진;이상은;양종훈
    • 한국콘텐츠학회논문지
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    • 제17권11호
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    • pp.554-566
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    • 2017
  • 우리나라는 방송법 등을 통해 방송이 특정정당이나 후보자에 대해 정치적 중립을 유지하도록 하고 있다. 그러나 박근혜 대통령 탄핵과 관련해 MBC와 JTBC는 보수와 진보로 양분돼 보도함으로써 공정성에 대한 논란이 일었다. 이러한 논란을 실증적으로 살펴보기 위해 탄핵이 인용된 날부터 일주일간 양 방송사의 저녁종합뉴스의 아이템 수 변화, 주제의 편향성, 뉴스 프레임을 등 3가지 측면을 분석하였다. 연구결과 JTBC와 MBC의 관련 보도는 양적으로 현저한 차이를 보였고, JTBC는 촛불집회 쪽에, MBC는 태극기집회 쪽 관련 주제를 집중적으로 보도했다. 뉴스 프레임 측면에서 MBC는 탄핵인용 관련 보도에서 박근혜 대통령과 이를 옹호하는 태극기집회 참여자들 쪽에서, JTBC는 반대로 반 박근혜 대통령과 탄핵의 정당성을 주장하는 촛불집회 참여자 입장에서 보도한 것으로 나타났다.