• Title/Summary/Keyword: replication control

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Polymerization of Polyethylene Using Bimodal TiCl4/MgCl2/SBA-15/MCM-41

  • Moonyakmoon, Mattanawadee;Klinsrisuk, Sujitra;Poonsawat, Choosak
    • Particle and aerosol research
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    • v.11 no.3
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    • pp.87-92
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    • 2015
  • MCM-41 (Mobil Composition of Matter) and SBA-15 (Santa Barbara Amorphous) were used as a supported catalyst for ethylene polymerization due to their combination of large surface area and wide range of pore size distribution. The morphology of supports was used to control the morphology of the resulting polymer. Different molar ratios of Al/Ti were used for ethylene polymerization at $60^{\circ}C$ under atmospheric pressure. The effect of different mass ratios of MCM-41/SBA-15 and 1-hexene concentration on polymerization activity and polymer properties was investigated. The catalytic activity and the crystallinity reached the highest value at Al/Ti of 480. Upon incorporation of MCM-41 and SBA-15 into $MgCl_2/TiCl_4$ catalyst, the molecular weight and crystallinity of polyethylene were enhanced. The obtained polyethylene showed melting temperature between 130 and $135^{\circ}C$. The polyethylene with replication structure of support and bimodal MWD was expected.

Analysis on the Performance Characteristics of LMS & CMA Adaptive Array Antenna for $\pi$/4 QPSK Signal ($\pi$ /4 QPSK신호에 대한 LMS와 CMA적응 배열안테나의 동작특성 분석)

  • 이종룡;이우재;주창복
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.2 no.1
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    • pp.71-77
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    • 1998
  • In this Paper, the training principles and the control method of adaptive array antennas using the LMS and CMA algorithms for the $\pi$/4 QPSK signal is showed and the convergence characteristics, the adaptivity of directional pattern SINR and the replication of desired signal of adaptive arrays are compared and discussed each other. Computer simulation results showed that the SINR of LMS adaptive array was 13.8[dB], and that of CMA was 12.8[dB], and also the convergence characteristics of LMS was fast a little than that of CMA. The LMS adaptive array was also performed null point well for the interference signal direction than that of the CMA adaptive array.

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Small Molecule Drug Candidates for Managing the Clinical Symptoms of COVID-19: a Narrative Review

  • Yun, Chawon;Lee, Hyun Jae;Lee, Choong Jae
    • Biomolecules & Therapeutics
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    • v.29 no.6
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    • pp.571-581
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    • 2021
  • Towards the end of 2019, an atypical acute respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was identified in Wuhan, China and subsequently named Coronavirus disease 2019 (COVID-19). The rapid dissemination of COVID-19 has provoked a global crisis in public health. COVID-19 has been reported to cause sepsis, severe infections in the respiratory tract, multiple organ failure, and pulmonary fibrosis, all of which might induce mortality. Although several vaccines for COVID-19 are currently being administered worldwide, the COVID-19 pandemic is not yet effectively under control. Therefore, novel therapeutic agents to eradicate the cause of the disease and/or manage the clinical symptoms of COVID-19 should be developed to effectively regulate the current pandemic. In this review, we discuss the possibility of managing the clinical symptoms of COVID-19 using natural products derived from medicinal plants used for controlling pulmonary inflammatory diseases in folk medicine. Diverse natural products have been reported to exert potential antiviral effects in vitro by affecting viral replication, entry into host cells, assembly in host cells, and release. However, the in vivo antiviral effects and clinical antiviral efficacies of these natural products against SARS-CoV-2 have not been successfully proven to date. Thus, these properties need to be elucidated through further investigations, including randomized clinical trials, in order to develop optimal and ideal therapeutic candidates for COVID-19.

Dynamism Competent LEACH Replication Deliberate for Wireless Sensor Network

  • KONDA HARI KRISHNA;TAPSI NAGPAL;Y. SURESH BABU
    • International Journal of Computer Science & Network Security
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    • v.23 no.5
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    • pp.7-12
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    • 2023
  • Remote sensor systems are utilized in a few applications, including military, restorative, ecological and family unit. In every one of these applications, vitality use is the deciding component in the execution of wireless sensor systems. Thusly, strategies for information steering and exchanging to the base station are critical in light of the fact that the sensor hubs keep running on battery control and the vitality accessible for sensors is constrained. There are two explanations for the various leveled directing Low Energy Adaptive Clustering Hierarchy convention be in investigated. One, the sensor systems are thick and a considerable measure of excess is engaged with correspondence. Second, with a specific end goal to build the versatility of the sensor arrange remembering the security parts of correspondence. In this exploration paper usage of LEACH steering convention utilizing NS2 test system lastly upgraded vitality productive EE-LEACH directing convention guarantees that the chose cluster heads will be consistently conveyed over the system with a specific end goal to enhance the execution of the LEACH convention. EE-LEACH enhances vitality utilization by around 43%.

Effects of dietary fiber in gestating sow diets - A review

  • Hyunwoong Jo;Beob Gyun Kim
    • Animal Bioscience
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    • v.36 no.11
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    • pp.1619-1631
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    • 2023
  • The objective of this review was to provide an overview of the effects of dietary fiber (DF) on reproductive performance in gestating sows. Dietary fibers have been suggested to modulate microbiota in the intestine and the immune system of gestating sows and to improve gut health. Thus, DF may help alleviate the adverse effects of the stressful production cycle of gestating sows. These benefits may subsequently result in improved reproductive performance of sows. Previous studies have reported changes in microbiota by providing gestating sows with DF, and the responses of microbiota varied depending on the source of DF. The responses by providing DF to gestating sows were inconsistent for antioxidative capacity, hormonal response, and inflammatory response among the studies. The effects of DF on reproductive performance were also inconsistent among the previous studies. Potential reasons contributing to these inconsistent results would include variability in reproductive performance data, insufficient replication, influence of other nutrients contained in the DF diets, characteristics of DF, and experimental periods. The present meta-analysis suggests that increasing the total DF concentration by 10 percentage units (e.g., 12% to 22% as-fed basis) in gestating sow diets compared to the control group improves the litter born alive by 0.49 pigs per litter. However, based on the present review, questions remain regarding the benefits of fibers in gestating sow diets. Further research is warranted to clarify the mode of action of fibers and the association with subsequent reproductive performance in gestating sows.

IFN-γ: A Crucial Player in the Fight Against HBV Infection?

  • Marine Laure Bettina Hillaire;Philip Lawrence;Brice Lagrange
    • IMMUNE NETWORK
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    • v.23 no.4
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    • pp.30.1-30.18
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    • 2023
  • About 0.8 million people die because of hepatitis B virus (HBV) infection each year. In around 5% of infected adults, the immune system is ineffective in countering HBV infection, leading to chronic hepatitis B (CHB). CHB is associated with hepatocellular carcinoma, which can lead to patient death. Unfortunately, although current treatments against CHB allow control of HBV infection, they are unable to achieve complete eradication of the virus. Cytokines of the IFN family represent part of the innate immune system and are key players in virus elimination. IFN secretion induces the expression of interferon stimulated genes, producing proteins that have antiviral properties and that are essential to cell-autonomous immunity. IFN-α is commonly used as a therapeutic approach for CHB. In addition, IFN-γ has been identified as the main IFN family member responsible for HBV eradication during acute infection. In this review, we summarize the key evidence gained from cellular or animal models of HBV replication or infection concerning the potential anti-HBV roles of IFN-γ with a particular focus on some IFN-γ-inducible genes.

The Impact of Calcium Depletion on Proliferation of Chlorella sorokiniana Strain DSCG150

  • Soontae Kang;Seungchan Cho;Danhee Jeong;Urim Kim;Jeongsug Kim;Sangmuk Lee;Yuchul Jung
    • Journal of Microbiology and Biotechnology
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    • v.34 no.7
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    • pp.1425-1432
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    • 2024
  • This study analyzed the effects of Ca2+ metal ions among culture medium components on the Chlorella sorokiniana strain DSCG150 strain cell growth. The C. sorokiniana strain DSCG150 grew based on a multiple fission cell cycle and growth became stagnant in the absence of metal ions in the medium, particularly Ca2+. Flow cytometry and confocal microscopic image analysis results showed that in the absence of Ca2+, cell growth became stagnant as the cells accumulated into four autospores and could not transform into daughter cells. Genetic analysis showed that the absence of Ca2+ caused upregulation of calmodulin (calA) and cell division control protein 2 (CDC2_1) genes, and downregulation of origin of replication complex subunit 6 (ORC6) and dual specificity protein phosphatase CDC14A (CDC14A) genes. Analysis of gene expression patterns by qRT-PCR showed that the absence of Ca2+ did not affect cell cycle progression up to 4n autospore, but it inhibited Chlorella cell fission (liberation of autospores). The addition of Ca2+ to cells cultivated in the absence of Ca2+ resulted in an increase in n cell population, leading to the resumption of C. sorokiniana growth. These findings suggest that Ca2+ plays a crucial role in the fission process in Chlorella.

Investigation of Conservative Genes in 168 Archaebacterial Strains (168개 고세균 균주들의 보존적 유전자에 관한 연구)

  • Lee, Dong-Geun;Lee, Sang-Hyeon
    • Journal of Life Science
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    • v.30 no.9
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    • pp.813-818
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    • 2020
  • The archaeal clusters of orthologous genes (arCOG) algorithm, which identifies common genes among archaebacterial genomes, was used to identify conservative genes among 168 archaebacterial strains. The numbers of conserved orthologs were 14, 10, 9, and 8 arCOGs in 168, 167, 166, and 165 strains, respectively. Among 41 conserved arCOGs, 13 were related to function J (translation, ribosomal structure, and biogenesis), and 10 were related to function L (replication, recombination, and repair). Among the 14 conserved arCOGs in all 168 strains, 6 arCOGs of tRNA synthetase comprised the highest proportion. Of the remaining 8 arCOGs, 2 are involved in reactions with ribosomes, 2 for tRNA synthesis, 2 for DNA replication, and 2 for transcription. These results showed the importance of protein expression in archaea. For the classes or orders having 3 or more members, genomic analysis was performed by averaging the distance values of the conservative arCOGs. Classes Archaeoglobi and Thermoplasmata of the phylum Euryarchaeota showed the lowest and the highest average of distance value, respectively. This study can provides data necessary for basic scientific research and the development of antibacterial agents and tumor control.

Effects of Dietary Delta-Aminolevulinic Acid on Egg Production and Egg Quality in Laying Hens (산란계에 있어 델타-아미노레블린산의 급여가 생산성 및 계란 품질에 미치는 영향)

  • Hong, J.W.;Shin, S.O.;Cho, J.H.;Chen, Y.J.;Yoo, J.S.;Lee, J.H.;Jang, H.D.;Kim, H.J.;Kim, I.H.
    • Korean Journal of Poultry Science
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    • v.34 no.3
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    • pp.181-185
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    • 2007
  • This study was conducted to evaluate the effects of dietary delta-aminolevulinic acid (ALA) on egg production and egg quality in laying hens. A total of 114 (30-wk age) ISA brown commercial hens were used in current trial for 28 days. Dietary treatments included 1) CON (basal diet), 2) 0.05 (basal diet + ALA 0.05%), 3) 0.1 (basal diet + ALA 0.1%) and 4) 0.2 (basal diet + ALA 0.2%). There were four dietary treatments with four replication per treatment and twelve laying hens per replication. During the overall period, egg production was quadratically affected (P=0.01) by ALA supplementation compared with control treatment. Egg weight increased (linear effect, P=0.01; quadratic effect, P=0.01) as the level of delta-aminolevulinic acid supplementation increased in the diets. Yolk color was increased quadratically (P=0.03). The difference of hemoglobin concentration was increased (quadratic effect, P=0.01) as the level of delta-aminolevulinic acid supplementation increased in the diets. In conclusion, the results of the experiment suggest that dietary delta-aminolevulinic acid could affect egg weight, yolk color and hemoglobin concentration in laying hens.

Effect of lighting regimes on amino acid and fatty acid contents of broiler chicken meat (점등체계가 육계 닭고기의 아미노산과 지방산 조성에 미치는 영향)

  • Na, Jae-Cheon;Park, Sung-Bok;Kang, Hwan-Ku;Kim, Dong-Wook;Kim, Min-Ji;Bang, Han-Tae;Chae, Hyun-Seok;Choi, Hee-Chul;Suh, Ok-Suk;Hong, Eui-Chul
    • Korean Journal of Agricultural Science
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    • v.38 no.4
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    • pp.695-701
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    • 2011
  • The study was carried out to investigate the effect of lighting regimes on performance and meat quality of broiler. A total of 912 chicks was divided into 2 groups with male (3 replications/group, 34 heads/replication) and female (3 replications/group, 42 heads/replication). Treatments were control (C, natural lighting), T1 treatment (24L), and T2 treatment (1~2d, 24L; 2~4d, 23L+1D; 4~16d, 16L+8D; 16~21d, 18L+6D; 21~42d, 23L+1D) by lighting regimes. Lysine content of male chicken meats at T2 treatment was lower compared to that of other treatments (p<0.05). There was no significant difference in all nonessential amino acid (AA) among treatments. Methionine content of female chicken meats at T2 treatment was lower compared to that of other treatments (p<0.05). The rate of C16:0, C16:1n7, and C18:1n9 of male chicken meat at T2 treatment was higher than that of other treatments (p<0.05), while C18:2n6 was lower at T2 treatment than other treatment (p<0.05). Mono-saturated fatty acid was the highest at T2 treatment, however, polysaturated fatty acid was the lowest at that treatment (p<0.05). There was no considerable difference in fatty acid composition of female chicken meat among treatments. Finally, lighting regime didn' affect on amino acid and fatty acid contents, and used possibly on energy reduction.