• 한방안이비인후피부과학회지
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• 제24권3호
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• pp.1-16
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• 2011

Objective : In the theory of Korean medicine, Scrophulariae Radix (SR) can clear away heat and cool the blood, nourish yin and promote the production of the body fluids, relieve toxin and benefit the throat. The present study was carried out to investigate effects of SR on allergic contact dermatitis (ACD) induced by 2,4-dinitrochlorobenzene (DNCB) in mice. Methods : In this experiment, effects of SR on clinical aspects on the skin, histopathological changes such as spongiosis, mast cell distribution, immune cell infiltration in tissue, spleen / body ratio and production levels of serum cytokines were investigated in vivo. In addition, effects on cell viability and release of b-hexosaminidase and histamine were also investigated in vitro. Results : SR treatment diminished erythema, desquamation and keratosis which were induced by repeated painting of DNCB. Spongiosis and edema were diminished by painting of SR in histopathological observation, infiltrations of mast cell and monocytes were also decreased in SR group. In addition, spleen / body ratio was lowered compared to ADC control group. Production level of IFN-${\gamma}$ in serum was decreased, but level of IL-4 did not affected by SR. Finally, more than 400 ${\mu}g/ml$ of SR treatment groups showed decreased cell viabilities in RBL-2H3 cells. Treatment with over 200 ${\mu}g/ml$ of SR decreased b-hexosaminidase release, and treatment with over 400 ${\mu}g/ml$ decreased histamine release in vitro. Conclusion : these data suggest that SR can decrease symptoms of ACD, then SR is useful to treat patient with ACD.

• 한국임상수의학회지
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• 제34권4호
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• pp.249-254
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• 2017

The cutaneous microcirculation plays a role in various physiological processes and pathological conditions. Two non-invasive methods were used in this study to obtain reference values for cutaneous microcirculation in intact male beagles. Twenty intact male beagles were used. The experimental environments were standardized. Laser Doppler flowmetry was used to measure cutaneous blood flow, and an infrared thermometer was used to measure cutaneous temperature. The blood flow and temperature were measured from the right side of the subjects at 20 cutaneous sites. Based on the laser Doppler flowmetry, the region with the highest blood flow was the periocular region that with the lowest was the forelimb foot pad. In addition, the standard deviation of the chest wall was the highest while that of the periocular region was the lowest. For skin temperature, the inguinal region had the highest mean skin temperature and the forelimb foot pad had the lowest. The correlation coefficient between the two methods was 0.72. Similar to a previous study, the values derived from repeated measurements at the 20 regions are reproducible and can contribute to research. Compared to the results of a previous study, the temperatures of the two smallest skin regions were the same; however, no specific trend was observed. The correlation coefficient between the two methods was significantly comparable, and this good correlation can reduce their limitations and variables complementarily. In addition to possible use in human studies, accumulated resources on measurements of skin blood flow in the future will potentiate its use in the veterinary medicine field.

• Structural Engineering and Mechanics
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• 제64권5호
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• pp.671-681
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• 2017

This study investigates the structural performance of 3D steel pipe rack suspended scaffolding systems. For the purpose, a standard full scale 3D steel pipe rack suspended scaffolding system considering two frames, two plane trusses, purlins and wooden floor is constructed in the laboratory. A developed load transmission system was placed in these experimental systems to distribute single loads to the center of a specific area in a step-by-step manner using a load jack. After each load increment, the displacements are measured by means of linear variable differential transducers placed in several critical points of the system. The tests are repeated for five different system conditions to determine the structural performance. The means of system conditions is the numbers of the tie bars which are used to connect plane trusses under level. Finite elements models of the 3D steel pipe rack suspended scaffolding systems considering different systems conditions are constituted using SAP2000 software to support the experimental tests and to use the models in future studies. Each of models including load transmission platform is analyzed under a single loading and the displacements are obtained. In addition, to calibrate the numerical models some uncertain parameters such as elasticity modulus of wooden floor and connection rigidity of purlins to plane trusses are assessed experimentally. The results of this work demonstrate that when increasing numbers of tie bars the displacement values are decreased. Also the results obtained from developed numerical models have harmony with those of experimental. In addition, the scaffolding system with two tie bars at the beginning and at the end of the plane truss has the optimum structural performance compared the results obtained for other scaffolding system conditions.

• Asian-Australasian Journal of Animal Sciences
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• 제19권7호
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• pp.1040-1046
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• 2006

Studies were carried out with a repeated $4{\times}4$ Latin square design with eight cannulated pigs fed four experimental diets to investigate the effect of dietary fiber and starch sources on apparent ileal and fecal amino acid digestibility. Each period lasted 15 d, with diet acclimation from d 1 to 7, feces collection for 48 h on d 8 to 9 and ileal sample collection for 12 h on d 13 to 15. The four experimental diets consisted mainly of cooked rice with the addition of protein sources (CON), partial replacement of cooked rice with either potato starch (PS), sugar beet pulp (SBP) or wheat bran (WB). Chromic oxide was used as an indigestible marker. With the exception of histidine, lysine and tryptophan, no differences were observed in the apparent ileal digestibility of amino acids between diets. The inclusion of potato starch did not affect the ileal and fecal amino acid digestibility. In comparison with diet CON, a decreased (p<0.05) ileal digestibility of histidine was found in pigs fed diet SBP, while the ileal digestibilities of histidine, lysine and tryptophan were decreased (p<0.05) by the inclusion of wheat bran. Inclusion of fiber sources (sugar beet pulp and wheat bran) caused a reduction (p<0.05) in the fecal amino acid digestibility and the net disappearance of amino acids in the large intestine. Of the indispensable amino acids, there was a 'net synthesis' for methionine in the large intestine of pigs when diets were supplemented with dietary fiber. The decrease in fecal amino acid digestibility with the addition of dietary fiber indicates an increase in the synthesis of bacterial protein in the large intestine.

• Ocean and Polar Research
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• 제34권1호
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• pp.73-83
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• 2012

Antarctica is very sensitive to climate change but the number of stations is not sufficient to accurately analyze climate change in this regoin. Model reanalysis data supplements the lack of observation and can be used as long term data to verify climate change. In this study, the 20CR (Twentieth Century Reanalysis) Project data from NCEP/NCAR and monthly mean data (temperature, solar radiation and longwave radiation) from 1871 to 2008, was used to analyze the temperature trend and change in radiation. The 20CR data was used to validate the observation data from Antarctica since 1950 and the correlation coefficients between these data were determined to be over 0.95 at all stations. The temperature increased by approximately $0.23^{\circ}C$/decade during the study period and over $0.20^{\circ}C$/decade over all of the months. This increasing trend was observed throughout the Antarctica and a slight increase was observed in the Antarctic Peninsula. In addition, solar radiation (surface) and longwave radiation (surface and top of atmosphere) trends correlated with the increase in temperature. As a result, outgoing longwave radiation at the surface is attenuated by atmospheric water vapor or clouds and radiation at the top of the atmosphere was reduced. In addition, the absorbed energy in the atmosphere increases the temperature of the atmosphere and surface, and then the heated surface emits more longwave radiation. Eventually these processes are repeated in a positive feedback loop, which results in a continuous rise in temperature.

• 한국수학교육학회지시리즈A:수학교육
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• 제47권4호
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• pp.519-543
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• 2008

The study has been conducted with 29 children from 4th to 6th grades to realize how they understand addition, subtraction, multiplication, and division of whole numbers, and how their understanding influences solving of one-step word problems. Children's understanding of operations was categorized into "adding" and "combination" for additions, "taking away" and "comparison" for subtractions, "equal groups," "rectangular arrange," "ratio," and "Cartesian product" for multiplications, and "sharing," "measuring," "comparison," "ratio," "multiplicative inverse," and "repeated subtraction" for divisions. Overall, additions were mostly understood additions as "adding"(86.2%), subtractions as "taking away"(86.2%), multiplications as "equal groups"(100%), and divisions as "sharing"(82.8%). This result consisted with the Fischbein's intuitive models except for additions. Most children tended to solve the word problems based on their conceptual structure of the four arithmetic operations. Even though their conceptual structure of arithmetic operations helps to better solve problems, this tendency resulted in wrong solutions when problem situations were not related to their conceptual structure. Children in the same category of understanding for each operations showed some common features while solving the word problems. As children's understanding of operations significantly influences their solutions to word problems, they needs to be exposed to many different problem situations of the four arithmetic operations. Furthermore, the focus of teaching needs to be the meaning of each operations rather than computational algorithm.

• 한국전문물리치료학회지
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• 제24권1호
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• pp.86-96
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• 2017

Background: Scapular dyskinesis is characterized by altered scapular position and motion. Specifically, excess activation of the Upper trapezius (UT) combined with decreased Lower trapezius (LT) and Serratus anterior (SA) have been observed. The Standard push-up plus exercise (SPP) is considered as a therapeutic exercise for increasing SA activity and maintaining the scapular kinematics. In addition, Using the Sling surface can lead to higher muscle activity. However, the advantage of an unstable surface has been uncertatin. Objects: To compare the activation of the UT, LT, and lower serratus anterior (LSA) muscles during various push-up plus exercises with and without sling in subjects with scapular dyskinesis. Methods: Total 18 male subjects with scapular dyskinesis were recruited. The UT, LT, and LSA electromyographic activities and the UT/LSA and UT/LT EMG activity ratios were measured during three push-up plus exercises with and without sling. Two-way repeated of analysis of variance was used to determine the statistical significance. Results: The UT activity was significantly lower in all postures without sling than that with sling. In addition, the LSA activity was significantly greater without than with sling, and significantly large in SPP, Low back supported push-up plus (LSPP), and Quadruped push-up plus. Additionally, the UT/LSA and UT/LT activity ratios were lower in SPP and LSPP without sling than with the other four push-up plus exercises. Conclusion: The push-up plus without sling were considered to decrease UT and increase LSA activity compared with exercises with sling. Furthermore, SPP without sling seems to be a more effective exercise for increasing LSA activity and lowering the UT/LSA and UT/LT activity ratios in scapular dyskinesis subjects.

• Nuclear Engineering and Technology
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• 제44권4호
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• pp.369-378
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• 2012

A load-following operation in APR+ nuclear plants is necessary to reduce the need to adjust the boric acid concentration and to efficiently control the control rods for flexible operation. In particular, a disproportion in the axial flux distribution, which is normally caused by a load-following operation in a reactor core, causes xenon oscillation because the absorption cross-section of xenon is extremely large and its effects in a reactor are delayed by the iodine precursor. A model predictive control (MPC) method was used to design an automatic load-following controller for the integrated thermal power level and axial shape index (ASI) control for APR+ nuclear plants. Some tracking controllers employ the current tracking command only. On the other hand, the MPC can achieve better tracking performance because it considers future commands in addition to the current tracking command. The basic concept of the MPC is to solve an optimization problem for generating finite future control inputs at the current time and to implement as the current control input only the first control input among the solutions of the finite time steps. At the next time step, the procedure to solve the optimization problem is then repeated. The support vector regression (SVR) model that is used widely for function approximation problems is used to predict the future outputs based on previous inputs and outputs. In addition, a genetic algorithm is employed to minimize the objective function of a MPC control algorithm with multiple constraints. The power level and ASI are controlled by regulating the control banks and part-strength control banks together with an automatic adjustment of the boric acid concentration. The 3-dimensional MASTER code, which models APR+ nuclear plants, is interfaced to the proposed controller to confirm the performance of the controlling reactor power level and ASI. Numerical simulations showed that the proposed controller exhibits very fast tracking responses.

• 한국수소및신에너지학회논문집
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• 제27권6호
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• pp.712-720
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• 2016

When bioethanol and water are mixed at a proper ratio, phase separation can occur because of the immiscibility of biobutanol with water. Phase separation in bioethanol blends fuels is a major problem for gasoline vehicle users due to effect of octane number and component corrosion. Thus, in this study, the phase separation of bioethanol was examined effect of bioethanol blends (E3 (3 vo.% bioethanol in gasoline), E5 and E10) in presence of water. The effect were evaluated behavior with phase separation test, simulation test of fuel tank in gas station according to water addition volume and it was investigated change of water content, bioethanol content and octane number for gasoline phase in bioethanol blends (E3, E5 and E10) every 1 week after water addition. The E3 occurred phase separation more easily than the E5 and E10 in small water contents because solubility of water on ethanol content difference in gasoline-ethanol. It was kept a initial level of water content, bioethanol content, and octane number by repeated sample replacing in simulation test of fuel tank.

• PNF and Movement
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• 제17권3호
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• pp.379-389
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• 2019

Purpose: This study examined the effects of wheelchair handle directions on the trunk muscle activity of adult males when climbing ramps. It also evaluated the wheelchair attendant's physical discomfort during tasks. Methods: Healthy males aged over 20 years were chosen and the direction of wheelchair handle grip was randomly selected. The grips included a general grip with ulnar deviation, a medial grip with wrist pronation, and a neutral grip with a neutral wrist. The trunk muscle activity was measured using surface electromyography. Furthermore, the physical discomfort of wheelchair attendants was subjectively evaluated using the Borg CR-10 Scale, which rates the perceived exertion. In addition, the SPSS 18.0 program was used perform repeated measure ANOVA to compare muscle activity and subjective discomfort during the interventions. The contrast test was also conducted with a significance level (α) of 0.05. Results: There was significant difference between the general grip and the medial grip in the rhomboid major muscle and the lumbar erector spinae muscle (p<0.05). In addition, there was significant difference between the general grip and the neutral grip in the rhomboid major muscle and the lumbar erector spinae muscle (p<0.05). Further, there was significant difference between the general grip and the neutral grip in subjective discomfort (p<0.05). Conclusion: In this study, adult male trunk muscle activity and subjective discomfort were lowest when using the neutral grip while climbing ramps. Accordingly, we suggest that neutral grips will help improve the function of the musculoskeletal system and reduce the subjective discomfort by putting less strain on the trunk muscles and maximizing efficiency with less force.