• Title/Summary/Keyword: reliability sensitivity

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A Effect of Unreliable Default Parameter in Forecasting Delay and Level of Service of Signalized Intersection (초기변수의 불확실성이 신호교차로 지체모형 및 서비스수준 예측에 미치는 영향 분석)

  • Kim, Sung-Deuk;Park, Won-Kyu;Kim, Kyung-Kyu
    • Journal of Navigation and Port Research
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    • v.27 no.4
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    • pp.471-478
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    • 2003
  • In the Signalized Intersection, the capacity analysis is conducted with a large amount of input data such as road way, traffic and signal condition. but the level of service(LOS) is determined by delay estimated as a measure of effectiveness (MOE) based on this procedure. However, It is under the circumstances which are not considered for the errors caused by the uncertainty of input data in the field(the turing volumes, lane geometry, signal timing, grade of approach lane, percentage heavy vehicles, peak hour factor and arrival type etc.) as become the bases in the determination of the capacity and LOS. It includes the problem of reliability which is not verified for the capacity and LOS estimated. So, this study is to suggest the minimization of their influences by examining whether the uncertainty of input data such as the traffic volume, percentage of heavy vehicles and roadway geometry on the approach lane in the intersection under the study affects the capacity analysis and LOS determination.

The Stability Evaluation of River Embankment for a Piping Phenomenon (하천제방의 세굴에 대한 안정성 연구)

  • Lee, Song;Park, Hyung-Kyu
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.7 no.3
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    • pp.175-181
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    • 2003
  • In this reseach, a seepage test is carried out for three kinds of soil using a upward seepage equipment. Reliability about the existing method of pipining investigation were verified making an estimate of the critical velocity, the critical hydraulic gradient, and hydraulic conductivity and so on. Also, sensitive analyses were carried out using Plaxis that is FEM Program about design factors of scour. The height of core had a big infulence on the hydraulic gradient of the embankment's lower part in the result of sensitive anaylsis. Also, second only to the height of core, and the slope of embankment, the width of crest had influence on scour. However, the change of hydraulic gradient in the effluent gateway had a little influence on the crest width of core. Using these results of sensitive analysis on designing, hydraulic gradient in the effluence gateway turned out to be reducing by altering design factors that change of sensitiveness is big, in case of the hydraulic gradient bigger than the standard hydraulic gradient.

Ultra-fast Generic LC-MS/MS Method for High-Throughput Quantification in Drug Discovery

  • Kim, So-Hee;Yoo, Hye Hyun;Cha, Eun-Ju;Jeong, Eun Sook;Kim, Ho Jun;Kim, Dong Hyun;Lee, Jaeick
    • Mass Spectrometry Letters
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    • v.4 no.3
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    • pp.47-50
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    • 2013
  • An ultra-fast generic LC-MS/MS method was developed for high-throughput quantification of discovery pharmacokinetic (PK) samples and its reliability was verified. The method involves a simple protein precipitation for sample preparation and the analysis by ultra-fast generic LC-MS/MS with the ballistic gradient program and selected reaction monitoring (SRM) mode. Approximately 290 new chemical entities (NCEs) (over 10,000 samples) from 5 therapeutic programs were analyzed. The calibration curves showed good linearity in the concentration range of 1, 2 or 5 to 2000 ng/mL. No significant ion suppression was observed in the elution region of all the NCEs. When approximately 300 plasma samples were continuously analyzed, the peak area of internal standard was constant and reproducible. In the repeated analysis of samples, the plasma concentrations and the area under the curve (AUC) were consistent with the results from the first analysis. These results showed that the present ultra-fast generic LC-MS/MS method is reliable in terms of selectivity, sensitivity, and reproducibility and could be useful for high-throughput quantification and other bioanalysis in drug discovery.

Development and Verification of Analytical Model of a Pilot Operated Flow Control Valve for 21-ton Electric Excavator (21톤급 전기 굴삭기용 파일럿 작동식 유량제어 밸브의 해석모델 개발 및 검증)

  • Kim, D.M.;Nam, Y.Y.;Seo, J.H.;Jang, J.S.
    • Journal of Drive and Control
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    • v.12 no.3
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    • pp.52-59
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    • 2015
  • An electro hydraulic poppet valve (EHPV) and a variable orifice poppet are assembled in a single block, which is referred to as a RHINO but is also generally called a pilot-operated flow control valve. In this study, we analyzed the structure and the operating principle for a RHINO applied in a 21-ton electric excavator system. The RHINO was experimentally tested to measure the dynamic responses and the pressure energy loss. In this test, we investigated the variation in the conductance coefficient according to the increase in the supply pressure under a constant current and a variation in the flow rate according to the increase in the current. Then, the geometrical shapes and the spring stiffness of the RHINO were considered to develop an analysis model. The characteristics (current-force and hysteresis) for the solenoid based on the experimental data were reflected in the analysis model that was developed, and the reliability of the analysis model was also verified by comparing the experimental and analytical results. The developed model is thus considered to be reliable for use in a wide range of applications, including optimum design, sensitivity analysis, parameter tuning, etc.

An Automated Draft Report Generator for Peripheral Blood Smear Examinations Based on Complete Blood Count Parameters

  • Kim, Young-gon;Kwon, Jung Ah;Moon, Yeonsook;Park, Seong Jun;Kim, Sangwook;Lee, Hyun-A;Ko, Sun-Young;Chang, Eun-Ah;Nam, Myung-Hyun;Lim, Chae Seung;Yoon, Soo-Young
    • Annals of Laboratory Medicine
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    • v.38 no.6
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    • pp.512-517
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    • 2018
  • Background: Complete blood count (CBC) results play an important role in peripheral blood smear (PBS) examinations. Many descriptions in PBS reports may simply be translated from CBC parameters. We developed a computer program that automatically generates a PBS draft report based on CBC parameters and age- and sex-matched reference ranges. Methods: The Java programming language was used to develop a computer program that supports a graphical user interface. Four hematology analyzers from three different laboratories were tested: Sysmex XE-5000 (Sysmex, Kobe, Japan), Sysmex XN-9000 (Sysmex), DxH800 (Beckman Coulter, Brea, CA, USA), and ADVIA 2120i (Siemens Healthcare Diagnostics, Eschborn, Germany). Input data files containing 862 CBC results were generated from hematology analyzers, middlewares, or laboratory information systems. The draft reports were compared with the content of input data files. Results: We developed a computer program that reads CBC results from a data file and automatically writes a draft PBS report. Age- and sex-matched reference ranges can be automatically applied. After examining PBS, users can modify the draft report based on microscopic findings. Recommendations such as suggestions for further evaluations are also provided based on morphological findings, and they can be modified by users. The program was compatible with all four hematology analyzers tested. Conclusions: Our program is expected to reduce the time required to manually incorporate CBC results into PBS reports. Systematic inclusion of CBC results could help improve the reliability and sensitivity of PBS examinations.

Diagnosis of Rotator Cuff Tears with Non-Arthrographic MR Imaging: 3D Fat-Suppressed Isotropic Intermediate-Weighted Turbo Spin-Echo Sequence versus Conventional 2D Sequences at 3T

  • Hong, Won Sun;Jee, Won-Hee;Lee, So-Yeon;Chun, Chang-Woo;Jung, Joon-Yong;Kim, Yang-Soo
    • Investigative Magnetic Resonance Imaging
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    • v.22 no.4
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    • pp.229-239
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    • 2018
  • Purpose: To assess the diagnostic performance in detecting rotator cuff tears at 3T of non-arthrographic shoulder magnetic resonance imaging (MRI) using 3D isotropic turbo spin-echo (TSE-SPACE) sequence as compared with 2D sequences. Materials and Methods: Seventy-four patients who were arthroscopically confirmed to have underwent non-arthrographic shoulder MRI with 2D sequences and TSE-SPACE were included. Three independent readers retrospectively scored supraspinatus and infraspinatus tendon (SST-IST) and subscapularis tendon (SCT) tears on 2D sequences and TSE-SPACE. Results: The mean sensitivity, specificity, and accuracy of the three readers were 95%, 100%, and 95% on TSE-SPACE and 99%, 93%, and 98% on 2D sequences for detecting SST-IST tears, respectively, whereas those were 87%, 49%, and 68% on TSESPACE and 88%, 66%, and 77% on 2D sequences for detecting SCT tears, respectively. There was no statistical difference between the two sequences, except for in the specificity of one reader for detecting SCT tears. The mean AUCs of the three readers on TSE-SPACE and 2D sequences were 0.96 and 0.98 for detecting SST-IST tears, respectively, which were not significantly different, while those were 0.71 and 0.82 for detecting SCT tears, respectively, which were significantly different (P < 0.05). Conclusion: TSE-SPACE may have accuracy and reliability comparable to conventional 2D sequences for SST-IST tears at non-arthrographic 3T shoulder MRI, whereas TSE-SPACE was less reliable than conventional 2D sequences for detecting SCT tears.

Development of Energy Harvesting Technologies Platform for Self-Power Rechargeable Pacemaker Medical Device. (자가발전 심장박동기를 위한 에너지 수확 플랫폼 개발)

  • Park, Hyun-Moon;Lee, Jung-Chul;Kim, Byunng-Soo
    • The Journal of the Korea institute of electronic communication sciences
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    • v.14 no.3
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    • pp.619-626
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    • 2019
  • The advances of semiconductor and circuitry technology dovetailed with nano processing techniques have further enhanced micro-miniaturization, sensitivity, longevity and reliability in MID(Medical Implant Device). Nevertheless, one of the remaining challenges is whether power can sufficiently and continuously be supplied for the operation of the MID. Self-powered MID that harvest biomechanical energy from human motion, respiratory and muscle movement are part of a paradigm shift. In this paper, we developed a rechargeable pacemaker through self-power generation with the triboelectric nanogenerator. We demonstrate a fully implanted pacemaker based on an implantable triboelectric nanogenerator, which act as a storage as well as active movement on a large-animal(dog) scale. The self-power pacemaker harvested from animal motion is 2.47V, which is higher than the required pacemaker device sensing voltage(1.35V).

Dental students' ability to detect maxillary sinus abnormalities: A comparison between panoramic radiography and cone-beam computed tomography

  • Rosado, Lucas de Paula Lopes;Barbosa, Izabele Sales;de Aquino, Sibele Nascimento;Junqueira, Rafael Binato;Verner, Francielle Silvestre
    • Imaging Science in Dentistry
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    • v.49 no.3
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    • pp.191-199
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    • 2019
  • Purpose: To compare the diagnostic ability of undergraduate dental students to detect maxillary sinus abnormalities in panoramic radiographs(PR) and cone-beam computed tomography (CBCT). Materials and Methods: This was a retrospective study based on the evaluation of PR and CBCT images. A pilot study was conducted to determine the number of students eligible to participate in the study. The images were evaluated by 2 students, and 280 maxillary sinuses were assessed using the following categories: normal, mucosal thickening, sinus polyp, antral pseudocyst, nonspecific opacification, periostitis, antrolith, and antrolith associated with mucosal thickening. The reference standard was established by the consensus of 2 oral radiologists based on the CBCT images. The kappa test, receiver operating characteristic curves, and 1-way analysis of variance with the Tukey-Kramer post-hoc test were employed. Results: Intraobserver and interobserver reliability showed agreement ranging from substantial (0.809) to almost perfect (0.922). The agreement between the students' evaluations and the reference standard was reasonable (0.258) for PR and substantial(0.692) for CBCT. Comparisons of values of sensitivity, specificity, and accuracy showed that CBCT was significantly better(P<0.05). Conclusion: CBCT was better than PR for the detection of maxillary sinus abnormalities by dental students. However, CBCT should only be requested after a careful analysis of PR by students and more experienced professionals.

A Study on the Quantitative Measurement of In-plane Displacement of Carbon Steel for Machine Structures according to Rolling Direction using a dual-beam Shear Interferometer (듀얼 빔 전단간섭계를 이용한 압연방향에 따른 기계구조용 탄소강의 면내 변위 정량적 측정에 대한 연구)

  • Kang, Chan-Geun;Kim, Sang Chae;Kim, Han-Sub;Lee, Hang-Seo;Jung, Hyun-il;Jung, Hyun-Chul;Song, Jae-Geun;Kim, Kyeong-suk
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.20 no.4
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    • pp.39-48
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    • 2021
  • In this paper, an in-plane deformation measuring system using a dual-beam shear interferometer was constructed to measure the in-plane deformation of the measuring object. The in-plane deformation of the object was quantitatively measured according to the load and surface treatment conditions of the object. We also verified the reliability of the proposed technique by simultaneously performing the technique with an electronic speckle pattern interferometry system (ESPI), which is another laser application measurement technology. Digital shearography directly measures the deformation gradient or strain components and has the advantages of being full-field, noncontact, highly sensitive, and robust. It offers a much higher measurement sensitivity compared with noncoherent measurement methods and is more robust and applicable to in-field tests.

Evaluation of Heat Waves Predictability of Korean Integrated Model (한국형수치예보모델 KIM의 폭염 예측 성능 검증)

  • Jung, Jiyoung;Lee, Eun-Hee;Park, Hye-Jin
    • Atmosphere
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    • v.32 no.4
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    • pp.277-295
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    • 2022
  • The global weather prediction model, Korean Integrated Model (KIM), has been in operation since April 2020 by the Korea Meteorological Administration. This study assessed the performance of heat waves (HWs) in Korea in 2020. Case experiments during 2018-2020 were conducted to support the reliability of assessment, and the factors which affect predictability of the HWs were analyzed. Simulated expansion and retreat of the Tibetan High and North Pacific High during the 2020 HW had a good agreement with the analysis. However, the model showed significant cold biases in the maximum surface temperature. It was found that the temperature bias was highly related to underestimation of downward shortwave radiation at surface, which was linked to cloudiness. KIM tended to overestimate nighttime clouds that delayed the dissipation of cloud in the morning, which affected the shortage of downward solar radiation. The vertical profiles of temperature and moisture showed that cold bias and trapped moisture in the lower atmosphere produce favorable conditions for cloud formation over the Yellow Sea, which affected overestimation of cloud in downwind land. Sensitivity test was performed to reduce model bias, which was done by modulating moisture mixing parameter in the boundary layer scheme. Results indicated that the daytime temperature errors were reduced by increase in surface solar irradiance with enhanced cloud dissipation. This study suggested that not only the synoptic features but also the accuracy of low-level temperature and moisture condition played an important role in predicting the maximum temperature during the HWs in medium-range forecasts.