• Journal of Pharmaceutical Investigation
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• v.39 no.4
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• pp.269-273
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• 2009

The objective of this investigation was to develop a gastro-retentive(GR) dosage form of gabapentin and was to evaluate of its dissolution characteristics. GR tablet consists of expandable core tablet matrix and semi-permeable membrane coating. Poloxamer 407 and sodium bicarbonate were used to prepare the core matrix. Polyvinly acetate dispersion (Kollicoat $SR30D^{(R)}$) and polyvinyl alcohol-polyethylene glycol copolymer ((Kollicoat $IR^{(R)}$)) were employed to form the semi-permeable membrane. The GR tablets significantly expanded up to fivefold in simulated gastrointestinal fluids with no apparent damage of the coating membrane over 12 hours. Also, the swelling rate was controllable with the amount of sodium bicarbonate. The drug release was observed to be substantially sustained based on coating level. The release rate of gabapentin from the GR tablet was gradually slowed down as the coasting amount was increased. The gabapentin GR tablet with 8% coating level showed a pseudo-zero order release kinetics over 12 hours. These results suggest that this swellable GR tablet system having semi-permeable membrane coating can be applicable for hydrophilic drug substances like gabapentin.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.43 no.3
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• pp.262-269
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• 2010

Seventeen fish species were counted in an underwater visual census, and the most common species, Sebastes inermis and Halichoeres poecilopterus, were released. More than 60% of the released S.inermis occurred near a fish farm 5 days after release, but they moved to a distant rocky area, and decreasing numbers were seen near the farm 90 days after release. In pots, a total of 722 individuals belonging to 43 species occurred, and released S.inermis dominated with 174 individuals recaptured during the study period. The other common fish species were Stephanolepis cirrhifer and Acanthopagrus schlegeli. The percentage of recapture was 0.23%, but declined to 0.12% at 90 days after release. The potential predators of released S.inermis included Lateolabrax japonicus and Sebastes schlegeli.

• Journal of Advanced Marine Engineering and Technology
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• v.23 no.2
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• pp.184-191
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• 1999

Th effects of exhaust gas recirculation(EGR) on the characteristics of combustion exhaust emissions and specific fuel consumption(SFC) are experimentally investigated by four-cylin-der four-cycle and direct injection marine diesel engine. In order to reduce soot contents in the recirculated exhaust gas to intake system of the engines a novel diesel soot removal system with a cylinder-type scrubber which has water injector(4 nozzles in 1.0mm diameter)is specially designed and manufactured for the experi-mental system. The obtained results are as follows; The combustion pressure in cylinder is decreased and ignition is delayed with increasing EGR rate. The accumulated quantity of heat release is slightly decreased and the tendency of heat release rate is not constant. NOx and Soot emissions are decreased by maximum 7% and 540% with scrubber tan without scrubber in the range of experimental conditions. Those are increased at the lean burn area with increasing equivalence ration in the constant value of engine speed and EGR rate. Also those are decreased with increasing EGR rate in the constant value of engine speed and equivalence ratio.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.32 no.8
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• pp.574-581
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• 2008

The characteristics of combustion and flow for a lean premixed flame in lab-scale gas turbine combustor was studied through experiment and numerical analysis. From the experiment, flame structure and heat release rate were obtained from OH emission spectroscopy. Qualitative comparisons were made line-integrated OH chemiluminescence image and abel-transformed one. NOx analyzer was implemented to get the characteristic of NOx exhaust from the combustor. From the numerical analysis, the thermal distribution and characteristic of recirculation zone with the change of fuel-air mixing degree, the characteristic of methane distribution with equivalence ratio in the combustor respectively. Total heat release rate is increased with increasing equivalence ratio. Thermal Nox is reduced with increasing fuel-air mixing degree. Increasing equivalence ratio results in the decrease of the size of reaction zone and alteration of the position of the reaction zone into the entrance of the combustor.

• Fire Science and Engineering
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• v.32 no.5
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• pp.6-14
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• 2018

This study was carried out with respect to the heat release rate (HRR) properties of building wood. Heat release characteristics were measured using a cone calorimeter (ISO 5660-1) with four kinds of wood. The time to ignition measured after the combustion in $25kW/m^2$ external heat flux was 35 to 55 s. Time to ignition of both lauan and red pine was marked with the most delayed value in each of 54 s, 55 s. The maximum heat release rate ($HRR_{peak}$) was $156.87{\sim}235.1kW/m^2$, and the risk of early fire was highest in spruce. Total heat release of red pine was obtained in the highest value with $114.2MJ/m^2$. The mean effective heat of combustion of Japanese cedar was 19.1 MJ/kg and the highest among the samples. Fire risk of wood by FPI was orderly increased from lauan ($0.2468s{\cdot}m^2/kW$), red pine ($0.2339s{\cdot}m^2/kW$), spruce ($0.2308s{\cdot}m^2/kW$) to Japanese cedar ($0.2231s{\cdot}m^2/kW$). Fire risk of wood by FGI get increased from lauan ($0.5088kW/m^2{\cdot}s$), red pine ($0.5111kW/m^2{\cdot}s$), Japanese cedar ($2.8522kW/m^2{\cdot}s$) to spruce ($3.0662kW/m^2{\cdot}s$). Therefore, the risk of fire on the heat release characteristics of woods were found that spruce and Japanese cedar showed the high value compared with the other specimens.

• Journal of The Korean Society of Agricultural Engineers
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• v.58 no.3
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• pp.47-56
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• 2016

Superabsorbent Polymers (SAPs) are hydrophilic synthetic polymers which could absorb water by hundreds of their own weight. They are used for multiple purpose including hygienic goods, soil conditioners, and hospital supplies. It is necessary to investigate the standard of their use including the amendment rate for soil application in agricultural fields. It is also important to understand their effects on the soil water content and engineering characteristics. The objective of this study is to find the water absorbing capacity and reusability of SAPs, and the characteristics of water release and effect of them on soil water content and engineering characteristics. In the result, SAPs per unit weight (1 g) used for this research could absorb about 200 g of water in max. The water absorbing capacity decreased after SAPs were used repeatedly. Released water of SAPs could provide the soils with about 9 % of the soil water content. Soil water content increased with decreasing distance from the SAPs. The distance of release was spreaded out with increasing water absorbed of SAPs. Finally, when a drainage and the capacity of soil water content were considered, it is recommended to amend the SAPs with soil by less than 0.25 %.

• Health Policy and Management
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• v.11 no.3
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• pp.121-150
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• 2001

This study was conducted to investigate provider's behavior change after releasing the information on the Cesarean section rate. Claims data filed at the National Health Insurance Corporation was used for this analysis and the focus of this study was the change of cesarean rate after the public disclosure of information. Average rates of the year 1999 and 2000 were compared, on the institutional basis, and range and coefficient of variation were estimated. For the last decade, Cesarean section rate has been increased dramatically. Clinical or demographic factors could not adequately explain the increase. Instead, nonclinical factors, such as financial incentive, physician's convenience, practice characteristics, etc., were more significant in explaining the increasing rate. Providers' behavior was significantly affected by the public release of information: after the release, average rate was decreased by 10.2%, and variations were also decreased. In particular, the extent of decrease was explained mainly by nonclinical factor rather than clinical ones. The results suggest that disseminating practice information to providers and consumers could contribute to reducing unnecessary medical service.

• Proceedings of the Polymer Society of Korea Conference
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• 2006.10a
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• pp.378-378
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• 2006

The preparation, characterization, and bio-testing of biocide incorporated silicone coatings for marine applications have been conducted. Derivatives of the biocide, Triclosan (5-chloro-2-(2, 4-dichlorophenoxy) phenol), were used to covalently attach the biocide moiety to a silicone backbone. The synthetic process allowed for control of the resulting coating's mechanical properties as well as antifouling/fouling release performance in laboratory and ocean site testing. The test results showed significantly reduce macro fouling with sustained fouling release characteristics for the coatings produced.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.24 no.8 s.179
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• pp.2115-2122
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• 2000

The understanding of impact-induced delamination is important in safety and reliability of composite structure. In this study, a model for arrest toughness is proposed in consideration of fracture behavior of composite materials. Also, the probabilistic model is proposed to describe the variability of arrest toughness due to the nonhomogeneity of material. For these models, experiments were conducted on the Carbon/Epoxy composite plates with various thickness using the impact hammer. The elastic work factor used in J-Integral is applicable to the evaluation of energy release rate. The fracture behavior can be described by crack arrest concept and the arrest toughness is independent of the delamination size. Additionally, a probabilistic characteristics of arrest toughness is well described by the Weibull distribution function. A variation of arrest toughness increases with specimen thickness.

• 한국전산유체공학회:학술대회논문집
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• 2008.03b
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• pp.609-613
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• 2008

The fire whirl occurring by the instability of atmosphere is a rare phenomenon, but highly destructive because it has high inhalation and lift force, caused by the rotating velocity. And it is difficult to extinguish the fire, because of increment of the spread rate with the flame height. In this study, for investigation of the flow characteristic of fire whirl for various heat release rate, numerical analysis is performed in same conditions with experiments, using the FDS which is developed at NIST. For validating of the numerical study, the results are compared with the experiment. The result shows that the relation between the characteristic length and the ratio of circulation versus the buoyancy force is $z_f$/D$^{\ast}$ = 0.304(${\Omega}/{\alpha}$)^2 - 1.334${\Omega}/{\alpha}$ + 5.516.