• 제목/요약/키워드: relaxation time

검색결과 1,080건 처리시간 0.026초

우(牛), 마(馬), 돈(豚) 및 견(犬)의 실질장기내(實質臟器內) Mast Cell 분포(分布)와 Rompun을 투여(投與)한 견(犬)의 Mast Cell 탈과립소견(脫顆粒所見) (Distribution of the Mast Cells in the Parenchymal Organs of the Cattle, Horses, Pigs, Dogs, and Rompun-induced Mast Cell Degranulation in the Dog)

  • 김태환;이차수
    • 대한수의학회지
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    • 제25권2호
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    • pp.113-123
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    • 1985
  • This paper dealt with the distribution of normal mast cells in the spleen, liver and lung on cattle, horses, pigs and dogs, and also degranulation of mast cells in the dogs infected with Rompun (2% Xylazine HCl). The results observed are summarized as follows. Normal mast cells were distributed in spleen, liver and lung on cattle, horse, pig and dog. Mast cells were observed in both red pulp and surroundings of white pulp of the spleen in horse, in the white pulp of the spleen in cattle, in the trabeculae of the spleen in pigs, and in white pulp and red pulp of the spleen in dogs, respectively. Mast cells were observed in the portal triad of the liver in cattle and horses, in both portal triad and interlobular connective tissues of the liver in pigs, and not only the portal triad but also walls of the sinusoids and the central veins in dogs. A large number of mast cells were observed in the interlobular septa and peribronchioles of lung on all the species in this experiment. The mast cells are more numerous in the lungs than other organs. Author considers that numbers of normal mast cells distributed in the tissue is related to the dosage of Rompun in animal. The degranulation of mast cells were observed in the subcutaneous tissues of dog intramuscularly injected with Rompun(0.5ml/times) for 4 or 5 times and subcutaneously injected with Rompun(0.3ml/times) for 4 times. In dog intradermally injected with 0.1ml of Rompun, mast cells were decreased in number at 30 minutes and markedly decreased in number at 2 hours, but more or less increased in number at 3 hours after injection. In addition, the granules of the mast cells were decreased in number at 30 minutes and marked degranulation of the mast cells were recognized at 2 hours after injections, but normal mast cells begun to appear in subcutaneous tissue with the lapse of time from 3 hours after injection. There was also observed local infiltration of neutrophils in subcutaneous tissues of dogs intradermally injected with 0.1ml of Rompun at 30 minutes. At 2 hours after injection, numerous neutrophils and a small number of eosinophils were observed in the site of injection. Conclusionally, Rompun was regarded as a factor which causes the degranulateon of mast cell and the authors considered that histamine released from the mast cells by Rompun might cause relaxation of skeletal muscle.

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코끼리 조개육이 동결저장중 단백질 조성 및 Texture변화에 미치는 Blanching의 영향 (Effect of Blanching on Protein Composition and Texture in Geoduck Muscle during Frozen Storage)

  • 유병진;정인학;이강호
    • 한국수산과학회지
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    • 제27권1호
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    • pp.33-40
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    • 1994
  • 코끼리 조개의 동결저장중 단백질조성 및 texture변화에 미치는 blanching의 영향에 대하여 조사한 결과는 다음과 같다. 생육에 있어서 근형질 단백질과 근원섬유 단백질은 급격한 감소현상을 보였으나 알카리가용성 단백질은 급격히 증가하였다. Blanching육에서는 근형질 단백질과 근원섬유 단백질은 완만하게 감소하였다. Blanching 시간에 있어서 2분간 처리한 시료가 관능검사에 의해 가장 texture가 우수하였는데 생육과 비교할 때 경도는 차이가 없었으나 탄성, 변형력 완화율은 낮은 값을 보였고 파괴신장율과 toughness은 높은 값을 나타내었다. 동결저장 중의 texture의 변화에 있어서 저장기간이 증가함에 따라 경도와 toughness은 생육과 blanching육 모두 증가하였으며 변형력 완화율은 저장초기 모두 급격히 감소되었다가 그 후로는 큰변화를 보이지 않았으며 파괴신장율은 생육의 경우 저장초기에 급속히 증가하였고 blanching육은 큰 변화가 없었다. 탄성에서는 생육은 점차적으로 감소하였고 blanching육은 증가하는 경향을 나타내었다.

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The Acute Effect of Trimetazidine on the High Frequency Fatigue in the Isolated Rat Diaphragm Muscle

  • Emre, Mustafa;Karayaylali, Lbrahim;San, Mustafa;Demirkazik, Ayse;Kavak, Servet
    • Archives of Pharmacal Research
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    • 제27권6호
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    • pp.646-652
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    • 2004
  • The objective of this study was to determine the acute effect of trimetazidine (TMZ) on the pre-fatigue, fatigue and post-fatigue contractile characteristics and tension-frequency relationships of isolated rat diaphragm muscle. Muscle strips were taken from the ventral-costal aspects of the diaphragm muscle of rats killed by decapitation. The muscle strips were suspended in organ baths containing Krebs solution, with a gas mixture of 95% $O_2$ and 5% $CO_2$ at $37^{\circ}C$ and pH 7.35-7.45. After determining the thermoregulation and optimum muscle length the muscles were subjected to direct supramaximal stimulation with 0.05 Hz frequency square pulses for periods of 0.5 msec to obtain control values. After adding $5{\times}10^{-6}{\;}and{\;}5{\times}10^{-5}$ M trimetazidine solution to the respective bath media, the contractile parameters of the muscles were recorded. The contractile parameters were also recorded for both the trimetazidine and tri-metazidine-free media after application of the high frequency fatigue protocols. Later, the tension-frequency relationship was determined by applying stimulating pulses of 10, 20, 50 and 100 Hz to the muscle strips. Whilst the twitch tension obtained from the $5{\times}10^{-6}{\;}and{\;}5{\times}10^{-5}$ M trimetazidine media showed numerical increases compared to that of the controls, these were not statistically significant (p>0.05). The contraction time exhibited a dose dependent increase (p<0.001), whilst the contraction and relaxation rates did not differ significantly. The isometric contraction forces obtained with the different stimulating frequencies showed a significant increase in the tetanic contraction only at 100 Hz (p<0.05). A comparison of the pre- and post-fatigue twitch tensions in the trimetazidine media showed the post- fatigue twitch tensions to be significantly higher than those of the pre-fatigue contraction forces (p<0.05). In the $5{\times}10^{-6}{\;}and{\;}5{\times}10^{-5}$ M trimetazidine media the increases in the post-fatigue contraction force were 22 and 30%, respectively. These results demonstrated that in isolated rat diaphragm muscle, TMZ significantly limited the mechanical performance decrease during fatigue. It is our opinion that trimetazidine contributed to the observed fatigue tolerance by eliminating the factors of fatigue, due to preservation of intracellular calcium homeostasis, provision of the ATP energy levels needed by ATPase dependent pumps and especially by keeping the intracellular pH within cer-tain limits.

Electroencephalographic brain frequency in athletes differs during visualization of a state of rest versus a state of exercise performance: a pilot study

  • Berk, Lee;Mali, Deeti;Bains, Gurinder;Madane, Bhagwant;Bradburn, Jessica;Acharya, Ruchi;Kumar, Ranjani;Juneja, Savleen;Desai, Nikita;Lee, Jinhyun;Lohman, Everett
    • Physical Therapy Rehabilitation Science
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    • 제4권1호
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    • pp.28-31
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    • 2015
  • Objective: Psychomotor imagery has been widely used to improve motor performance and motor learning. Recent research suggests that during visualization, changes occur in neurophysiological networks that make physical practice more effective in configuring functional networks for skillful behaviors. The aim of our pilot study was to determine if there was change and to what extent there was differentiation in modulation in electroencephalography (EEG) frequencies between visualizing a state of rest and a state of exercise performance and to identify the preponderant frequency. Design: Quasi-experimental design uncontrolled before and after study. Methods: EEG brain wave activity was recorded from 0-40 Hz from nine cerebral cortical scalp regions F3, Fz, F4, C3, Cz, C4, P3, POz, and P4 with a wireless telemetric EEG system. The subjects, while sitting on a chair with eyes closed, were asked to visualize themselves in a state of routine rest/relaxation and after a period of time in a state of their routine exercise performance. Results: The gamma frequency, 31-40 Hz, (${\gamma}$) was the predominant wave band in differentiation between visualizing a state of rest versus visualizing a state of exercise performance. Conclusions: We suggest these preliminarily findings show the EEG electrocortical activity for athletes is differentially modulated during visualization of exercise performance in comparison to rest with a predominant ${\gamma}$ wave band frequency observed during the state of exercise. Further controlled experimental studies will be performed to elaborate these observations and delineate the significance to optimization of psychomotor exercise performance.

능동 학습과 시간 문맥 정보를 이용한 작물 재배지역 분류 (Classification of Crop Cultivation Areas Using Active Learning and Temporal Contextual Information)

  • 김예슬;유희영;박노욱;이경도
    • 한국지리정보학회지
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    • 제18권3호
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    • pp.76-88
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    • 2015
  • 이 논문에서는 작물 재배지의 분류를 목적으로 능동 학습과 과거 토지 피복도 기반의 시간 문맥 정보를 결합하는 분류 방법론을 제안하였다. 신뢰성 높은 훈련 자료의 추출을 위하여 능동 학습 기반 반복 분류를 적용하였으며, 과거 토지 피복도의 작물 재배 규칙을 시간 문맥 정보로 정량화 하여 능동 학습 기법의 적용시 훈련 자료의 할당과 작물 간 분광학적 혼재 효과 완화에 이용하였다. 제안 분류 방법론의 적용 가능성을 평가하기 위해 미국 Illinois 주의 옥수수와 콩 재배지역의 구분을 목적으로 MODIS 시계열 식생지수 자료와 과거 cropland data layer(CDL) 자료를 이용한 사례연구를 수행하였다. 사례연구 결과, 초기 감독 분류 결과에서 나타났던 옥수수와 콩의 오분류와 기타 작물과 비작물의 오분류 양상이 능동 학습 기반 반복 분류를 통해 완화되었다. 그리고 CDL 자료로부터 추출한 시간 문맥 정보를 추가적으로 결합함으로써 주요 작물에서 나타나는 과추정 양상이 완화되어 가장 우수한 분류 정확도를 나타내었다. 따라서 제안 기법이 양질의 훈련 자료의 확보가 쉽지 않은 작물 재배지의 분류에 유용하게 적용될 수 있음을 확인하였다.

경남지역 간호사의 스트레스 수준 및 건강관련 행동 (Stress Level and Health-Related Behavior of Nurses Working in the Kyungnam Area)

  • 윤현숙;최윤영
    • 대한지역사회영양학회지
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    • 제8권5호
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    • pp.781-793
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    • 2003
  • This study was performed to investigate the stress level and health-related behaviors of nurses and to provide basic information for developing educational programs in the health care field. The subjects of this study were 197 nurses and 94 nursing assistants working at hospitals in the Kyung-nam area. A survey was conducted using a self-administered questionnaire in November, 2002. The results were as follows : The average age and work experience of the subjects were 26.9 and 5.6 years, respectively. The number of respondents in the shift and non-shift operations was equally distributed. The mean height and weight were 161.2 cm and 52.7 kg, respectively. Even though the average body mass index (BMI) and obesity index were normal in the subjects, 9.2% of the subjects were overweight/obese, while 28.9% of the subjects were under weight, according to the obesity index. The mean score of stress was 27.5 \pm$\pm$ 4.6 out of 50 points. Most of the subjects were highly stressed about the amount of their work, problems regarding their future, and relationships with their superiors. With regard to changes in food intake due to stress, 44.1% showed an increased intake, while 32.3% showed a reduced intake. The degree of health consciousness of the married nurses, those over 36 years of age, and those with over 10 years of nursing experience was significantly higher than that of the unmarried nurses, those under 35 years of age, and those with under 10 years of nursing experience (p<0.01). Fifty-one point three percent of the subjects thought their health status was unhealthy. Fifty-seven percent of the subjects had tried weight control. Their main reason for trying weight control was to have a slender figure (62.3%), and their methods of weight control were moderation in intake(45.6%), exercise and dieting (36.9%). TV/radio (49.5%) and newspaper/magazines (47.1%) were the primary sources of nutritional and health information for the subjects, and professional (25.1%) and the internet (13.4%) were ranked relatively highly. The food components of most concern to the subjects during meal time were (in order of importance) fats (51.9%), calories (40.2%) and salt (35.1%). The subjects considered 'taking a rest' (73.5%) as the most important factor in maintaining an optimal health status, followed by self-relaxation (56.4%), moderation in diet (39.5), bathing or using a sauna (25.7%) and exercising (22.7%).

Natural Rubber/Acrylonitrile-Butadiene Rubber 블렌드의 기계적 물성과 강선과의 접착거동 (Mechanical Properties of Natural Rubber/Acrylonitrile-Butadiene Rubber Blends and Their Adhesion Behavior with Steel Cords)

  • 손봉영;나창운
    • Elastomers and Composites
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    • 제36권2호
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    • pp.111-120
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    • 2001
  • NR/NBR 혼합고무 컴파운드의 기계적 물성과 아연 및 황동피복 강선과의 접착특성에 대해 NR/NBR 조성비에 대한 함수로 조사하였다. Mooney 점도와 응력이완시간은 NBR 함량의 증가에 따라 감소하였다. NBR 함량증가에 따라 모듈러스는 전반적으로 증가하였고, 인장강도의 경우 NBR 함량이 40 phr 이하일 경우 유사한 수준을 보이다가 $50{\sim}60\;phr$일 때 최소치를 보인 후 다시 증가하는 경향을 보인 반면, 파괴점에서의 변형은 NBR 함량이 50 phr 이하의 범위에서는 선형적인 감소를 보인 후 50 phr 이후에서는 거의 유사한 수준을 보였다. NR/NBR 혼합고무 컴파운드는 NR과 NBR의 유리전이온도인 $-10^{\circ}C$$-55^{\circ}C$에서 탄성모듈러스의 급격한 전이와 tan ${\delta}$ 피크를 나타내 비상용성 블렌드의 거동을 나타내었다. 접착력(pullout force)과 rubber coverage 공히 NBR 함량이 증가함에 따라 급격히 감소하여 NR/NBR 혼합비가 50/50인 경우 NR 컴파운드 대비 약 40% 수준을 보였고, 순수한 NBR 컴파운드의 경우 접착력은 다시 증가하여 NR 컴파운드 대비 약 90% 수준의 접착력을 보였다. Auger spectrometer 분석결과 NBR 함량이 증가할수록 황함량이 감소하였고, 이는 강선-고무간 접착계면에서 접착층이 충분히 성장하지 못했다는 것을 의미하고 접착성능 하락의 원인으로 해석하였다.

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천마성분인 4-hydroxy-3-methoxybenzaldehyde와 2,3-dihydroxy-benzaldehyde의 병용투여에 의한 진정효과 (Sedative Effects of Combined Administration of 4-Hydroxy-3-methoxybenzaldehyde, a Component of Gastrodia elata, and 2,3-Dihydroxybenzaldehyde in Rats)

  • 이동웅;최형철;이광윤;이수관;김정애;용철순;김진숙;허근;신손문;구병수;하정희
    • 생명과학회지
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    • 제16권7호
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    • pp.1214-1218
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    • 2006
  • 페놀성 화합물들의 병용투여가 rat의 진정효과에 미치는 영향을 조사하였다. 천마성분으로서 positive GABAergic neuromodulation을 보이는 4-hydroxy-3-methoxybenzaldehyde와 강력한 항산화물질인 2,3-dihydroxlrbenzaldehyde를 동량 투여한 결과, pentyleneterazole에 의해 유발된 사망률이 유의하게 감소되었으며 pentobarbital에 의해 유도된 수면시간은 유의하게 연장되었으나 항불안효과와 근육이완효과는 나타나지 않았다. 이러한 결과로 보아 항경련효과를 가진 화합물과 항산화 효과를 가진 화합물을 병용투여 함으로서 경련이나 불면 등의 신경증상을 효과적으로 억제할 수 있을 것으로 사료된다.

인천광역시 접경지역 토지이용규제에 관한 연구 (A Study on Land Use Regulation on Border Area of Incheon Metropolitan City)

  • 정진원;윤현위;이종현
    • 대한지리학회지
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    • 제51권2호
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    • pp.255-268
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    • 2016
  • 인천시 강화군 및 옹진군은 접경지역이라는 특수성으로 인해 군사규제 등의 상이한 토지이용규제를 적용받고 있으며, 행정구역상 수도권이라는 이유로 각종 토지이용규제를 중첩적으로 적용받으면서 경제적 낙후와 쇠퇴가 심화된 지역으로 전락하였다. 접경지역을 위한 접경지역지원특별법, 특수상황지역 개발사업 등 상이한 지원 또한 실시되고 있으나 지원사업의 비현실성, 법령의 위계 등의 문제로 여전히 규제로부터 자유롭지 못한 현실이다. 따라서 본 연구는 인천시 접경지역이 갖고 있는 지역적 특성, 즉 접경지역으로서 상이한 토지이용규제에 대한 중첩규제를 이제는 완화해야할 시점이라고 판단하고 본 연구를 실시하였다. 인천시 접경지역에 대한 군사규제의 유연한 해제 및 운영, 수도권정비계획법 규제완화, 문화재 보호구역 등의 완화 등을 통한 전반적인 토지이용규제의 완화가 요구되며, 특히 인천시 접경지역은 접경지역의 특수성과 수도권과의 지역적, 문화적 여건이 상이함을 인정하여 수도권 범위에서 제외시켜 중첩규제로 인한 피해를 최소화해야 할 것이다.

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시민농원의 이용동기와 만족도에 관한 연구 (A Study on the User's Motivation and Satisfaction for Civic Garden)

  • 노경아;김유일
    • 한국조경학회지
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    • 제22권4호
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    • pp.133-148
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    • 1995
  • This study was carried out to provide behavioral data for its planning and management of civic garden through the evaluation of user's motivation & satisfaction. The civic gardens around Seoul were surveyed. The site are located in Kwangtan-myeon, Sudong-myeon, Wonsam-myeon, Nam-myeon, Buknae-myeon, and Jumdong-myeon, A total of 244 questionnaires were completed by mail questionnaires. The results are as follows: 1. 82 percentage of users are in thirties or fourties most of them have children who go to the elementary school. 50 percentage of users are just typical house wifes. 74 percentage of users graduated form university. 60 percentage of users live in lofty apartment buildings. 2. As a result from factor analysis, their motivations are categorized into four fator groups.: 'to experience nature', 'weekend recreation', 'nostalgia', 'to provide their old parent's sparetime'. And their satisfactions are categorized into eleven fator groups.: 'psychological/intellectual component', 'recreational components', 'instruction/management', 'facility'. 'vegetable cultivation', 'social contact', 'crowing', 'aesthetic component', 'family contact', 'the terms of lease', 'visition time'. 3. The user of civic garden can be divided into four user groups by their motivation. CLUSTER1 can represent the user group who have motivations for 'leisure, relaxation'. They are considerably satisfied with all other factor 'opportunity of meeting new person'. CLUSTER2 at the age of 41 to 50 have motivation for 'health, nostalgia'. CLUSTER3 at the age of 31 to 40 have motivation for 'harvest, experiencing nature'. CLUSTER4 at the age of more than 51 want to let their parents enjoy their sparetime. They are dissatisfied with accessibility, amount of cultivation area, crowding and overall farm management. 4. The regression analysis was employed with predicting the overall satisfaction. The results of regression analysis showed that 69% of total variances was explained by six variables: The most effective variable is 'whether visiting on weekend or weekdays', the visitors on weekdays are far more satisfied than weekend visitors because of traffic congestion, and crowding. The second source of satisfactions are 'psychological/intellectual components', they are satisfied with 'family contact', 'the terms of lease' and 'instruction in farming' are sources of satisfaction or dissatisfaction, and finally 'aesthetic landscape' is the source of satisfaction. The second most important variable is psychological one. Even though the civic gardens were not well equipped, they liked the atmosphere of rural life, refreshness, nostalgia, satisfaction from cultivation plants, and sense of achievement.

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