• Title/Summary/Keyword: relative distance error rates

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Statistical Assessment of Biosimilarity based on the Relative Distance between Follow-on Biologics in the (k + 1)-Arm Parallel Design

  • Kang, Seung-Ho;Shin, Wooyoung
    • Communications for Statistical Applications and Methods
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    • v.22 no.6
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    • pp.605-613
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    • 2015
  • A three-arm parallel design has been proposed to assess the biosimilarity between a biological product and a reference product using relative distance (Kang and Chow, 2013). The three-arm parallel design consists of two arms for the reference product and one arm for the biosimilar product. This paper extended the three-arm parallel design to a (k + 1)-arm parallel design composed of k (${\geq}3$) arms for the reference product and one arm for the biosimilar product. A new relative distance was defined based on Euclidean distance; consequently, a corresponding test procedure was developed based on asymptotic distribution. Type I error rates and powers were investigated both theoretically and empirically.

A Study on the Performance Characteristics of a Chirp RTLS over Wireless Channel with Gaussian Noise (가우시안 잡음이 존재하는 무선채널에서 Chirp RTLS 시스템의 성능 특성에 관한 연구)

  • Kang, Byeong-Gwon
    • Journal of Digital Convergence
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    • v.11 no.7
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    • pp.201-207
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    • 2013
  • The chirp signaling has been mainly used in radar systems due to its good correlation characteristics, and nowadays it is applied to real time locating system(RTLS). The RTLS with chirp signaling was chosen as a standard such as ISO/IEC 24730-5 and IEEE 802.15.4a. In this paper, the performance of a real time locating system with chirp signaling was evaluated and simulated with relative distance error rates. We considered three cases of S/I = -30[dB], -20[dB], and -10[dB] with Rician factor K=10 and K=20. The performance was enhanced with K factor improvement by 25%, 27% and 50% for respective three cases of S/I. As results, in case of S/I < -20[dB], the minimum signal power is required for performance improvement even though the line of sight component is helpful. And also, in case of S/I ${\geq}$ -20[dB], as the line of sight component is stronger the better performance is obtained.

Optical-fiber Electronic Speckle Pattern Interferometry for Quantitative Measurement of Defects on Aluminum Liners in Composite Pressure Vessels

  • Kim, Seong Jong;Kang, Young June;Choi, Nak-Jung
    • Journal of the Optical Society of Korea
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    • v.17 no.1
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    • pp.50-56
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    • 2013
  • Optical-fiber electronic speckle pattern interferometry (ESPI) is a non-contact, non-destructive examination technique with the advantages of rapid measurement, high accuracy, and full-field measurement. The optical-fiber ESPI system used in this study was compact and portable with the advantages of easy set-up and signal acquisition. By suitably configuring the optical-fiber ESPI system, producing an image signal in a charge-coupled device camera, and periodically modulating beam phases, we obtained phase information from the speckle pattern using a four-step phase shifting algorithm. Moreover, we compared the actual defect size with that of interference fringes which appeared on a screen after calculating the pixel value according to the distance between the object and the CCD camera. Conventional methods of measuring defects are time-consuming and resource-intensive because the estimated values are relative. However, our simple method could quantitatively estimate the defect length by carrying out numerical analysis for obtaining values on the X-axis in a line profile. The results showed reliable values for average error rates and a decrease in the error rate with increasing defect length or pressure.

Verification of Mechanical Leaf Gap Error and VMAT Dose Distribution on Varian VitalBeamTM Linear Accelerator

  • Kim, Myeong Soo;Choi, Chang Heon;An, Hyun Joon;Son, Jae Man;Park, So-Yeon
    • Progress in Medical Physics
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    • v.29 no.2
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    • pp.66-72
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    • 2018
  • The proper position of a multi-leaf collimator (MLC) is essential for the quality of intensity-modulated radiation therapy (IMRT) and volumetric modulated arc radiotherapy (VMAT) dose delivery. Task Group (TG) 142 provides a quality assurance (QA) procedure for MLC position. Our study investigated the QA validation of the mechanical leaf gap measurement and the maintenance procedure. Two $VitalBeam^{TM}$ systems were evaluated to validate the acceptance of an MLC position. The dosimetric leaf gaps (DLGs) were measured for 6 MV, 6 MVFFF, 10 MV, and 15 MV photon beams. A solid water phantom was irradiated using $10{\times}10cm^2$ field size at source-to-surface distance (SSD) of 90 cm and depth of 10 cm. The portal dose image prediction (PDIP) calculation was implemented on a treatment planning system (TPS) called $Eclipse^{TM}$. A total of 20 VMAT plans were used to confirm the accuracy of dose distribution measured by an electronic portal imaging device (EPID) and those predicted by VMAT plans. The measured leaf gaps were 0.30 mm and 0.35 mm for VitalBeam 1 and 2, respectively. The DLG values decreased by an average of 6.9% and 5.9% after mechanical MLC adjustment. Although the passing rates increased slightly, by 1.5% (relative) and 1.2% (absolute) in arc 1, the average passing rates were still within the good dose delivery level (>95%). Our study shows the existence of a mechanical leaf gap error caused by a degenerated MLC motor. This can be recovered by reinitialization of MLC position on the machine control panel. Consequently, the QA procedure should be performed regularly to protect the MLC system.

A Study on the Interframe Image Coding Using Motion Compensated and Classified Vector Quantizer (Ⅱ : Hardware Implementation) (이동 보상과 분류 벡터 양자화기를 이용한 영상 부호화에 관한 연구 (Ⅱ: 하드웨어 실현))

  • Jeon, Joong-Nam;Shin, Tae-Min;Choi, Sung-Nam;Park, Kyu-Tae
    • Journal of the Korean Institute of Telematics and Electronics
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    • v.27 no.3
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    • pp.21-30
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    • 1990
  • This paper describes a hardware implementation of the interframe monochrome video CODEC using a MC-CVQ(Motion Compensated and Classified Vector Quantization) algorithm. The specifications of this CODEC are (1) the resolution of image is $128{\times}128$ pixels, and (2) the transmission rates are about 10frames/sec at the 64Kbps channel. In order to design the CODEC under these conditions, it is implemented by a multiprocessor system composed of MC unit, CVQ nuit and decoder unit, which are controlled by microprogramming technique. And the 3~stage pipelined ALU(Arithmetic and Logic Unit) is adopted to calculate the minimum error distance in the MC unit and CVQ nuit. The realized system shows that the transmission rates are 6-15 frames/sec according to the relative motion of the video signal.

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Implementation and Performance Evaluation of a Precision Localizing Device for Hyperloop Pods Driving at Ulta-High Speeds (초고속주행 하이퍼루프 포드의 정밀 위치측정 장치 구현 및 성능평가)

  • Ok, Min-Hwan;Choi, Su-Yong;Choe, Jae-Heon;Lee, Kwan-Sup
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.13 no.5
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    • pp.443-451
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    • 2020
  • A futuristic locomotion system called Hyperloop is projected for driving at ulta-high speed, levitated in the tube. In hyperloop localization of pods on the linear synchronous motor is essential for pod driving. precision localization is required for acceleration and deceleration of pods driving at speed above 1,000km/h, and also required for adjusting the pod speed driving at this very-high speed to maintain inter-vehicle distance. In this work, a new scale of localization is challenged by modified laser surface velocimeter. In acceleration the speed of a virtual pod is calculated along its displacement measured by laser reflection. Under the requirement of precise localization of the pod driving at ultra-high speed, a displacement measurement device, which detects the difference in reflections from tiles passing by the pod, is developed and evaluated through performance test. Tests of pod speeds below 500km/h have showed exact localization results of the precision in centimeters, and tests of pod speeds above 500km/h have showed localization with very low error rates under 0.1%. For the measurement above 500km/h, future works would pursue the error rate converges to zero.

The Flow-rate Measurements in a Multi-phase Flow Pipeline by Using a Clamp-on Sealed Radioisotope Cross Correlation Flowmeter (투과 감마선 계측신호의 Cross correlation 기법 적용에 의한 다중상 유체의 유량측정)

  • Kim, Jin-Seop;Kim, Jong-Bum;Kim, Jae-Ho;Lee, Na-Young;Jung, Sung-Hee
    • Journal of Radiation Protection and Research
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    • v.33 no.1
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    • pp.13-20
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    • 2008
  • The flow rate measurements in a multi-phase flow pipeline were evaluated quantitatively by means of a clamp-on sealed radioisotope based on a cross correlation signal processing technique. The flow rates were calculated by a determination of the transit time between two sealed gamma sources by using a cross correlation function following FFT filtering, then corrected with vapor fraction in the pipeline which was measured by the ${\gamma}$-ray attenuation method. The pipeline model was manufactured by acrylic resin(ID. 8 cm, L=3.5 m, t=10 mm), and the multi-phase flow patterns were realized by an injection of compressed $N_2$ gas. Two sealed gamma sources of $^{137}Cs$ (E=0.662 MeV, ${\Gamma}$ $factor=0.326\;R{\cdot}h^{-1}{\cdot}m^2{\cdot}Ci^{-1}$) of 20 mCi and 17 mCi, and radiation detectors of $2"{\times}2"$ NaI(Tl) scintillation counter (Eberline, SP-3) were used for this study. Under the given conditions(the distance between two sources: 4D(D; inner diameter), N/S ratio: $0.12{\sim}0.15$, sampling time ${\Delta}t$: 4msec), the measured flow rates showed the maximum. relative error of 1.7 % when compared to the real ones through the vapor content corrections($6.1\;%{\sim}9.2\;%$). From a subsequent experiment, it was proven that the closer the distance between the two sealed sources is, the more precise the measured flow rates are. Provided additional studies related to the selection of radioisotopes their activity, and an optimization of the experimental geometry are carried out, it is anticipated that a radioisotope application for flow rate measurements can be used as an important tool for monitoring multi-phase facilities belonging to petrochemical and refinery industries and contributes economically in the light of maintenance and control of them.