• 제목/요약/키워드: regulatory gene

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Nrf2 and Keap1 Regulation of Antioxidant and Phase II Enzyme Genes

  • Yamamoto, M.
    • 한국독성학회:학술대회논문집
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    • 한국독성학회 2002년도 Current Trends in Toxicological Sciences
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    • pp.24-42
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    • 2002
  • Antioxidant responsive element (ARE) mediates the transcriptional activation of the genes encoding phase II drug metabolizing enzymes and antioxidative stress genes. The ARE consensus sequence shows high similarity to NF-E2 binding sequence, a cisacting erythroid gene regulatory element.(omitted)

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