Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2002.05a
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- Pages.24-42
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- 2002
Nrf2 and Keap1 Regulation of Antioxidant and Phase II Enzyme Genes
- Yamamoto, M. (Center for TARA and Institute for Basic Medical Sciences, University of Tsukuba)
- Published : 2002.05.01
Abstract
Antioxidant responsive element (ARE) mediates the transcriptional activation of the genes encoding phase II drug metabolizing enzymes and antioxidative stress genes. The ARE consensus sequence shows high similarity to NF-E2 binding sequence, a cisacting erythroid gene regulatory element.(omitted)
Keywords