• Korean Journal of Veterinary Service
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• v.33 no.4
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• pp.345-351
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• 2010

Toxoplasma gondii is a species of parasitic protozoa in the genus Toxoplasma. The definitive host of T. gondii is the cat, but the parasite can be carried by the vast majority of warm-blooded animals, including humans. It is often found in the tissues of food animals including pigs and sheep. To determine the regional prevalence of infection with T. gondii, bloods (n=300) from domestic pigs and tissues (n=200) from slaughter pigs in Gyeongnam province were tested using an enzyme-linked immunosorbent assay (ELISA) and a polymerase chain reaction (PCR) for detection of antibody and antigen. A total of 115 sero-positive pigs were identified for a prevalence rate of 38.3%. Of the 50 herds from domestic pigs tested, 34 had at least one sero-positive pig for a herd prevalence rate of 68.0%. Sero-positive rates of pigs in fattening farm were higher than that of pigs in breeding company. Sero-positive rates of sows were higher than that of growing pigs. Seasonally, sero-positive rates of pigs were highest in winter (80.0%) and lowest in spring (23.8%). According to farm size, sero-positive rates of pigs were higher in small size farms (${\leq}$2,000) than that of big size farms (>2,000). However, none of the bloods (n=300) from domestic pigs and tissues (n=200) from slaughter pigs were positive for T. gondii specific DNA by PCR.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.13
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• pp.5299-5303
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• 2014

Background: To explore etiology for providing scientific clues for the prevention of lung cancer. Materials and Methods: Data for lung cancer incidence and meteorological geographic factors from 25 counties in Zhejiang province of China during 2011 were studied. Stepwise multiple regression and correlation analysis were performed to analyze the geographic distribution and epidemiology of lung cancer. Results: 8,291 new cases (5,998 in males and 2,293 females) of lung cancer during 2011 in Zhejiang province were reported in the 25 studied counties. Reported and standardized incidence rates for lung cancer were 58.0 and 47.0 per 100,000 population, respectively. The incidence of lung cancer increased with age. Geographic distribution analysis shows that the standardized incidence rates of lung cancer in northeastern Zhejiang province were higher than in the southwestern part, such as in Nanhu, Fuyang, Wuxing and Yuyao counties, where the rates were more than 50 per 100,000 population. In the southwestern Zhejiang province, for instance, in Yueqing, Xianju and Jiande counties, the standardized incidence rates of lung cancer were lower than 37 per 100,000 population. Spearman correlation tests showed that forest coverage rate, air quality index (AQI), and annual precipitation level are associated with the incidence of lung cancer. Conclusions: Lung cancer in Zhejiang province shows obvious regional differences. High incidence appears associated with low forest coverage rate, poor air quality and low annual precipitation. Therefore, increasing the forest coverage rate and controlling air pollution may play an important role in lung cancer prevention.

• The Journal of the Korea Contents Association
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• v.20 no.1
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• pp.530-538
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• 2020

Recently, the suicide rate problem in Korea is very serious. Local governments are pushing various policies to lower suicide rates. The purpose of this study is to assess the difference in the suicide rate among regions and to identify the trend of change by concentration index(CI). The major findings are as follows. First, county suicide rate was the highest in the last 20 years and the lowest in the city. The low suicide rate in urban areas continues. Second, suicide rates are increasing in all regions. But the gap between the district and the county was decreasing. The difference in suicide rates between urban and rural areas is decreasing. Third, the suicide rate concentration index was negative for all 20 years. Suicide rates in low-density farming and fishing villages. Fourth, the absolute value of the concentration index has been continuously decreasing for 20 years. The gap between suicide and rural areas is decreasing. Therefore, inter-regional suicide rate is estimated to be leveling up.

• Journal of Embryo Transfer
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• v.32 no.3
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• pp.153-157
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• 2017

This study was conducted to investigate the optimal artificial insemination (AI) time with diagnostic kit at ovulation time. We already applied the patent about the protein in the cow heat mucose in external reproductive tract. And we would examine the accuracy for detection of cow heat by the kit produced with the protein. Evaluation of optimal heat detection was tried two time at 12 hrs and 24 hrs after the heat. And then, AI service also performed two times with no relation to the results of heat diagnosis by heat detection kit and pregnancy rates were checked with rectal palpation on $60^{th}$ day after AI. Heat diagnostic results by kit in natural heat after 12 hrs in Hanwoo cows were showed 31.3~75.0% on positive in first heat detection and 33.3~100.0% on positve in second heat detection. In the $1^{st}$ positive results were significant different (p<0.05), but $2^{nd}$ positive were not. The results of heat detection showed different result on regional influence and individual cow effects. The pregnancy rates of first trial of heat detection were showed 34.4~78.7% on positive and 21.3~68.8% on negative after the diagnosis by heat detection kit. And the pregnancy rates of next trial of heat detection were showed 33.3~85.7% on positive and 14.3~66.6% on negative after the heat diagnosis. Both positive results of first trial and next trial also were showed significant different (p<0.05), but negative results were not. In positive result, first trial of total pregnancy rates was higher than the next trial of pregnancy, but there showed opposite results on negative results. In conclusion, the optimal heat detection kit is suitable to ordinary Hanwoo cows and it suggested that we have to improve the kit's accuracy by detecting the materials like proteins related optimal AI time.

• Journal of the Korean Society of Safety
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• v.36 no.1
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• pp.86-94
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• 2021

Lecture rooms are crowded with many attendees. Moreover, they rely significantly on the natural ventilation through windows for removing and controlling indoor contaminants such as CO₂. With the aim of broadening the understanding of the characteristics of natural ventilation phenomena in lecture rooms, the average individual CO₂ release rates of attendees were measured during the course of a lecture and compared with previously reported CO₂ release rates. In addition, the effects of natural ventilation through windows on the time-variant CO₂ concentrations in the center of the lecture room were measured and analyzed. Moreover, details about the overall and regional CO₂ concentrations, as well as the air flows in the lecture room, were simulated and analyzed with computational fluid dynamics software, Fluent 2020 R2. It was found that the average individual CO₂ release rates were slightly slower than previously reported rates. The local CO₂ concentrations in the lecture room for regions with a high density of attendees increased over a short period of time, although the natural ventilation was already started by opening the windows. The overall CO₂ concentration in the lecture room rapidly decreased in the early stage of ventilation, but declined very slowly after a longer period of ventilation time. Therefore, in order to enhance the efficiency of a lecture room's natural ventilation, it is recommended to homogeneously distribute the attendees in the lecture room, and to frequently open the windows for short periods of time.

• Journal of Technology Innovation
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• v.31 no.1
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• pp.29-63
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• 2023

The purpose of this study is to analyze the process of changes in regional science and technology policies in Korea and to seek future development directions. In Korea, regional science and technology policies have been implemented since the introduction of the local autonomy system. Since then, it has been implemented in earnest with the establishment of a central government-level plan. The regional science and technology policies have been developed to this day by interacting with national science and technology policies and regional development policies. Nevertheless, due to the path dependence and lock-in effect in the accumulated process, the regional science and technology policies are still subordinate to central government policies. Thus, the establishment of an independent ecosystem for local science and technology is still insufficient. Furthermore, the gap between regions is deepening, such as the growing of aging population, population decline due to low birth rates, job losses due to the recession of local key industry, and the concentration of the youth population in the metropolitan area. The transformation path such as digital transformation and carbon neutrality paradigm is expected to further widen regional disparities. In order to address a comprehensive problem, the implementing system of regional science and technology policies need to be newly established. A framework for reinvention of regional science and technology policy needed in the era of grand societal challenges have to be developed.

• Journal of Trauma and Injury
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• v.33 no.1
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• pp.31-37
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• 2020

Purpose: We aimed to evaluate the trauma volume and performance indicators during the first 5-year period of operation in a single regional trauma center. Methods: We analyzed prospectively collected data from the Korean Trauma Data Bank for a single regional trauma center between January 2014 and December 2018. More than 250 variables were analyzed. We calculated the predicted survival rates using the trauma and injury severity score (TRISS) method. Results: In total, there were 16,103 trauma admissions during the first 5 years; trauma activation was performed in 5,105 of these cases. Over 70% of the patients were men, and most of the admitted patients were within the age groups of 55-59 years for men and 75-79 years for women. Analyses were performed considering two patient groups: the total patient group and the group of those with severe trauma (injury severity score [ISS] >15). The median ISS, revised trauma score, and TRISS of the two groups were 5 (interquartile range [IQR] 4-10), 22 (IQR 17-27), and 7.6±0.99 and 6.74±1.9, 0.95±0.13, 0.81±2.67, respectively. Of the total patient group, 801 patients (5%) died in the hospital, whereas of the group of patients with ISS >15, 526 (19.5%) died. The direct transportation of patients to the regional trauma center increased year by year. The emergency room stay time and time to entering the operating room showed a decrease until 2017; however, these parameters increased again in 2018. Conclusions: The trauma volume in the regional trauma center is appropriate, and some improvements could be observed after its establishment. However, performance indicators reveal the prematurity of the trauma center and its potential for further improvements. Moreover, the development of a national trauma system, beyond regional trauma centers, is required.

• Journal of Korean Society on Water Environment
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• v.26 no.5
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• pp.841-849
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• 2010

Soil erosion is an natural phenomenon. However accelerated soil erosion has caused many environmental problems. To reduce soil loss from a watershed, many management practices have been proposed worldwide. To develop proper and efficient soil erosion best management practices, soil erosion rates should be estimated spatially and temporarily. The Universal Soil Loss Equation (USLE) and USLE-based soil erosion and sediment modelling systems have been developed and tested in many countries. The Sediment Assessment Tool for Effective Erosion Control (SATEEC) system has been developed and enhanced to provide ease-of-use interface to the USLE users. However many researchers and decision makers have requested to enhance the SATEEC system for simulation of soil erosion and sediment reflecting effects of single storm event. Thus, the SATEEC R factors were estimated based on 5 day antecedent rainfall data. The SATEEC 2.1 daily R factor was applied to the study watershed and it was found that the R2 and EI values (0.776 and 0.776 for calibration and 0.927 and 0.911 for validation) with the daily R were greater than those (0.721 and 0.720 for calibration and 0.906 and 0.881 for validation) with monthly R, which was available in the SATEEC 2.0 system. As shown in this study, the SATEEC with daily R can be used to estimate soil erosion and sediment yield at a watershed scale with higher accuracy. Thus the SATEEC with daily R can be efficiently used to develop site-specific soil erosion best management practices based on spatial and temporal analysis of soil erosion and sediment yield at a daily-time step, which was not possible with USLE-based soil erosion modeling system.

• Journal of the Economic Geographical Society of Korea
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• v.21 no.4
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• pp.321-334
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• 2018

There are many factors that cause uneven regional developments in the country and one of main factors is outflow of regional income or products. The purpose of this study is to analyze regional production runoff by comparing GRDP and GRNI in basic local governments level. In this study, GRNI of basic local governments are estimated by local income tax data, The results of the study are as follows. Firstly, GRNI is more concentrated than GRDP. The analysis of Moran I showed that the spatial autocor-relation of GRNI is more distinct than that of GRDP. Local Moran I analysis shows that spatial hot spots and cold spots are more apparent in GRNI than GRDP. Secondly, the outflows of GRDP into a small number of regions are apparent. In about 80% of basic local governments, the net outflows of GRDP occur. The large net outflow regions are cities where manufacturing industry has developed and in the 20 lowest net outflow rate regions, 70-80% of GRDP outflows. The large net inflow regions are metropolitan area in Seoul and large local cities. Seocho-gu, Yongsan-gu, and Gangnam-gu in Seoul have a large net inflows and net inflow rates are over 90% of GRDP.

• Korean Journal of Radiology
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• v.22 no.7
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• pp.1152-1162
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• 2021

Objective: This study aimed to determine whether there are regional differences in the blood-brain barrier (BBB) permeability of cognitively normal elderly participants and to identify factors influencing BBB permeability with a clinically feasible, 10-minute dynamic contrast-enhanced (DCE) MRI protocol. Materials and Methods: This IRB-approved prospective study recruited 35 cognitively normal adults (26 women; mean age, 64.5 ± 5.6 years) who underwent DCE T1-weighted imaging. Permeability maps (K_trans) were coregistered with masks to calculate the mean regional values. The paired t test and Friedman test were used to compare Ktrans between different regions. The relationships between K_trans and the factors of age, sex, education, cognition score, vascular risk burden, vascular factors on imaging, and medial temporal lobar atrophy were assessed using Pearson correlation and the Spearman rank test. Results: The mean permeability rates of the right and left hippocampi, as assessed with automatic segmentation, were 0.529 ± 0.472 and 0.585 ± 0.515 (K_trans, x 10^-3 min^-1), respectively. Concerning the deep gray matter, the K_trans of the thalamus was significantly greater than those of the putamen and hippocampus (p = 0.007, p = 0.041). Regarding the white matter, the K_trans value of the occipital white matter was significantly greater than those of the frontal, cingulate, and temporal white matter (p < 0.0001, p = 0.0007, p = 0.0002). The variations in K_trans across brain regions were not related to age, cognitive score, vascular risk burden, vascular risk factors on imaging, or medial temporal lobar atrophy in the study group. Conclusion: Our study demonstrated regional differences in BBB permeability (K_trans) in cognitively normal elderly adults using a clinically acceptable 10-minutes DCE imaging protocol. The regional differences suggest that the integrity of the BBB varies across the brains of cognitively normal elderly adults. We recommend considering regional differences in K_trans values when evaluating BBB permeability in patients with neurodegenerative diseases.