• Title/Summary/Keyword: regional materials

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Interaction of Tobacco Smoking and Chewing with Angiotensin Converting Enzyme (Insertion/Deletion) Gene Polymorphisms and Risk of Lung Cancer in a High Risk Area from Northeast India

  • Phukan, Rup Kumar;Borah, Prasanta Kumar;Saikia, Bhaskar Jyoti;Das, Mandakini;Sekhon, Gaganpreet Singh;Mahanta, Jagadish
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.24
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    • pp.10691-10695
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    • 2015
  • Background: Association of angiotensin converting enzyme (ACE) gene polymorphisms with lung cancer susceptibility remains uncertain and varies with ethnicity. Northeast India represents a geographically, culturally, and ethnically isolated population. The area reports an especially high rate of tobacco usage in a variety of ways of consumption, compared with the rest of the Indian population. Materials and Methods: We conducted a population based case control study in two major high risk region for lung cancer from Northeast India. A total of 151 consecutive lung cancer cases diagnosed histopathologically and equal numbers of controls were recruited with record of relevant sociodemographic information. Blood samples were collected and processed to identify ACE gene polymorphism. Results: Significantly higher (40.4 % vs 29.1%, OR=1.97, CI=1.04-3.72; p=0.037) prevalence of the ACE II genotype was observed among lung cancer cases. Smoking was significantly associated with increased risk of lung cancer (OR=1.70, CI=1.02-2.81; p=0.041). An enhanced risk was also observed for interaction of ACE II genotype with tobacco smoking (OR=4.09, CI=1.51-11.05; p=0.005) and chewing (OR=3.68, CI=1.22-11.13; p=0.021). Conclusions: The present study indicates significant association s of the ACE II genotype with lung cancer in high risk Northeast India.

The Clinicopathologic Features and Recurrence of Resection-Line Involvement of Gastric Cancer after Gastrectomy

  • Choi, Seong-Hee;Lee, Hyeong-Geun;Choi, Min-Gew;Noh, Jae-Hyung;Sohn, Tae-Sung;Bae, Jae-Moon;Kim, Sung
    • Journal of Gastric Cancer
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    • v.10 no.3
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    • pp.106-110
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    • 2010
  • Purpose: The purpose of this study was to analyze the clinical courses of patients with gastric cancer and positive resection margins after a gastrectomy for gastric cancer who did not undergo subsequent surgery. Materials and Methods: Among 4,452 patients who underwent surgery for gastric cancer from January 2001 to December 2007, 20 patients with positive resection margins after gastrectomy for gastric cancer who did not undergo subsequent surgery were included. The recurrence patterns were confirmed by postoperative computed tomography and gastroscopy, which were performed on a planned schedule. All recurrence patterns after gastrectomy were classified as loco-regional, peritoneal, or distant metastases. Results: The patients with confirmed recurrence all had advanced stage cancer (III-IV), and the recurrence sites were variable. However, peritoneal and distant recurrences were more common than loco-regional recurrences. The patients with loco-regional recurrence also had peritoneal and/or distant recurrence. Conclusions: Patients with gastric cancer and a positive resection margin showed more frequent peritoneal and distant metastases than loco-regional recurrence. In addition, patients with loco-regional recurrence also had peritoneal and distant recurrence. A positive resection margin of gastric cancer was related with poor histological differentiation, diffuse type, and advanced stage (III-IV).

Body Size Differences in Various Areas of China - Height, Bust Girth, Waist Girth - (중국(中國) 각(各) 지역(地域)의 인체(人體)사이즈 차이(差異)에 관(關)한 연구(硏究) - 키, 가슴둘레, 허리둘레를 중심(中心)으로 -)

  • Kwon, Young-Ja;Shim, Boo-Ja
    • Journal of Fashion Business
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    • v.7 no.5
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    • pp.66-82
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    • 2003
  • China shows body size differences owing to varied climates, economic development, living standards, and ethnic distribution from region to region. That's why some regional research regarding body sizes is necessary for the advancement of clothing goods into China. Here, the materials of the Chinese standard "GB/T 1335-1997 Clothing Sizes" are analyzed to reveal the somatotypes of Chinese adults. Height, chest girth and waist girth were differently noticed in six areas. 1. The distribution rates of four body types (Y, A, B, C) were diverse in six regions. 2. Regional differences were seen as follows: 1) As for the height of male adults, areas 1(Northeast, Hwabuk) and 2(Central Western) were larger than the national mean. Areas 3(Gwangdong, Gwangseo, Bokgeon), 4 (Unnam, Gwiju, Sacheon) and 5(Downstream Jang River) were rather small. 2) As for the height of female adults, areas 1, 2 and 6 (Midstream Jang River) were larger than the national mean. Areas 3 and 4 were smaller than the average. 3) As for the bust girth of male adults, area 1 was the only area that exceeded the national mean. Areas 3 and 4 turned out smaller than the average. 4) As for the bust girth of female adults, areas 1, 2 and 6 exceeded the national average. The other three areas were lower. 5) As to the waist girth of adult males, areas 1 and 2 exceeded the national average. The other four areas were lower. 6) As to the waist girth of adult females, areas 1, 2 and 6 exceeded the national average. Areas 4 and 5 were lower. 7) In the height, bust girth and waist girth of male and female adults, most regions showed differences in means, regional distribution and regional rates.

A working paradigm for managing mandibular fractures under regional anesthesia

  • Chellappa, Natarajan;Meshram, Vikas;Kende, Prajwalit;Landge, Jayant;Aggarwal, Neha;Tiwari, Manish
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.44 no.6
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    • pp.275-281
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    • 2018
  • Objectives: Isolated mandibular fractures contribute to approximately 45% of maxillofacial traumas. Improper management of mandibular fractures can cause myriad potential complications and can lead to serious functional and aesthetic sequelae. The objective of the study is to design a stepwise approach for managing isolated mandibular fractures using open reduction and internal fixation (ORIF) with regional anesthesia on outpatient basis. Materials and Methods: Patients with isolated mandibular fractures presenting to the department of maxillofacial surgery were selected for ORIF under regional anesthesia based on occlusion, age, socioeconomic status, general condition, habits, and allied medical ailments. Standard preoperative, intraoperative, and postoperative protocols were followed. All patients were followed up for a minimum of 4 weeks up to a maximum of 1 year. Results: Of 23 patients who received regional anesthesia, all but one had good postoperative functional occlusion. One patient was hypersensitive and had difficulty tolerating the procedure. Two patients developed an extraoral draining sinus, one of whom was managed with local curettage, while the other required hardware removal. One patient, who was a chronic alcoholic, returned 1 week after treatment with deranged fracture segments after he fell while intoxicated. Conclusion: With proper case selection following a stepwise protocol, the majority of mandibular fractures requiring ORIF can be managed with regional anesthesia and yield minimal to no complications.

Determination of Model Parameters of Surface Cover Materials in Evaluation of Sediment Reduction and Its Effects at Watershed Scale using SWAT (토양유실 저감을 위한 지표피복 저감효과 변수 결정 및 SWAT 모형 유역단위 효과 분석)

  • Kum, Donghyuk;Jang, Chun Hwa;Shin, Min Hwan;Choi, Joong-Dae;Kim, Bomchul;Jeong, Gyo-Cheol;Won, Chul Hee;Lim, Kyoung Jae
    • Journal of Korean Society on Water Environment
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    • v.28 no.6
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    • pp.923-932
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    • 2012
  • The purpose of this study was to determine parameters of surface cover materials and evaluation the effects on runoff and sediment reductions with rice straw mat with PAM at watershed scale using the SWAT model. In this study, 1) regression equation of CN for rice straw mat + PAM using SCS curve number method was developed, 2) the USLE P factor, being able to reflect simulation of rice straw mat + PAM in the agricultural field, was estimated for various slope scenarios with VFSMOD-w. Then regression equation for CN and USLE P factor were used as input data in the SWAT model. Assuming rice straw mat + PAM is applied to radish and potato fields, occupying 24% of agricultural fields at the study watershed. Result of direct runoff without rice straw mat + PAM was $65,964,368\;m^3,$ with rice straw mat + PAM, direct runoff was $65,637,336\;m^3$, $327,031.8\;m^3$ reductions compared without it. Also, result of sediment without rice straw mat + PAM was 163,531 ton, with rice straw mat + PAM, sediment was 84,779 ton, 78,752 ton reduction compared without it. This analysis showed that about 48% sediment reductions would be expected with rice straw mat + PAM. As shown in this study, rice straw mat + PAM would be used as an efficient site-specific BMPs to reduce runoff and sediment discharge from field.

Analysis of Risk Factors for Postoperative Morbidity in Perforated Peptic Ulcer

  • Kim, Jae-Myung;Jeong, Sang-Ho;Lee, Young-Joon;Park, Soon-Tae;Choi, Sang-Kyung;Hong, Soon-Chan;Jung, Eun-Jung;Ju, Young-Tae;Jeong, Chi-Young;Ha, Woo-Song
    • Journal of Gastric Cancer
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    • v.12 no.1
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    • pp.26-35
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    • 2012
  • Purpose: Emergency operations for perforated peptic ulcer are associated with a high incidence of postoperative complications. While several studies have investigated the impact of perioperative risk factors and underlying diseases on the postoperative morbidity after abdominal surgery, only a few have analyzed their role in perforated peptic ulcer disease. The purpose of this study was to determine any possible associations between postoperative morbidity and comorbid disease or perioperative risk factors in perforated peptic ulcer. Materials and Methods: In total, 142 consecutive patients, who underwent surgery for perforated peptic ulcer, at a single institution, between January 2005 and October 2010 were included in this study. The clinical data concerning the patient characteristics, operative methods, and complications were collected retrospectively. Results: The postoperative morbidity rate associated with perforated peptic ulcer operations was 36.6% (52/142). Univariate analysis revealed that a long operating time, the open surgical method, age (${\geq}60$), sex (female), high American Society of Anesthesiologists (ASA) score and presence of preoperative shock were significant perioperative risk factors for postoperative morbidity. Significant comorbid risk factors included hypertension, diabetes mellitus and pulmonary disease. Multivariate analysis revealed a long operating time, the open surgical method, high ASA score and the presence of preoperative shock were all independent risk factors for the postoperative morbidity in perforated peptic ulcer. Conclusions: A high ASA score, preoperative shock, open surgery and long operating time of more than 150 minutes are high risk factors for morbidity. However, there is no association between postoperative morbidity and comorbid disease in patients with a perforated peptic ulcer.

A Study on Activation Plan of Data Collection and Cooperation System in Local Council (지방의회 자료수집 및 협력체계의 활성화 방안 연구)

  • Kwack, Dong-Chul;Joung, Hyun-Tae
    • Journal of the Korean BIBLIA Society for library and Information Science
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    • v.24 no.2
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    • pp.129-150
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    • 2013
  • The libraries of local councils contribute to realize democracy and promote national interests and the welfare of the people, by supporting democratic legislation activities and congressional politics of the local councilors. This study analyzes the libraries of local councils at 17 regional local governments, and it confirms that there are various deviations in their library services such as material acquisitions and legislative information services by regional groups. On the basis of that analysis, the study summarizes the ways for improving the service qualities of the libraries of local councils as follows. First, it is necessary to organize the institute for national council materials. Second, the cooperative network systems should be constructed to share council publications. Third, the provisions related the copyright law and the national assembly library act have to be modified. Fourth, the libraries of local councils share their own materials focusing on digital publications. Fifth, the National Assembly Library expands their legislative information services to the libraries of local councils.

Monitoring and Analysis of Genetically Modified Ingredients of Imported Foods by PCR (PCR에 의한 수입식품의 유전자재조합 원료 분석 및 모니터링)

  • Kim, Hee-Yun;Park, Yong-Chjun;Ro, Hye-Lim;Jo, Jun-Il;Kim, Eun-Jung;Nam, Hae-Sun;Lee, Jin-Kyung;Lee, Jin-Ha;Kang, Yoon-Sook;Lee, Jong-Ook
    • Korean Journal of Food Science and Technology
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    • v.38 no.5
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    • pp.605-608
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    • 2006
  • Genetically modified (GM) ingredients found in imported raw materials and processed foods were monitored in the province Gyeongin in Korea. The analysis was performed according to "Testing methods for genetically modified foods of food standards and specifications" established in Korea. We received 120 items from the Gyeongin Regional KFDA. Only two of the 120 items analyzed in the samples, were contaminated with GM ingredients. However, we could not analyze the internal standard gene from 12 processed foods. We found that the extracted total DNA of the above 12 samples were extracted and found to be degraded. The total DNA contained a very small fragment of less than 300 base pair. Therefore, it seems that the total DNA is not large enough to serve as the template DNA for PCR analysis.

On the Influence Each Other Between the Monks in the Buddhist Temples and the Society in Towns or Villages (중국(中國) 지방사회(地方社會)와 불교사원(佛敎寺院) 그리고 승인(僧人)의 상호(相互) 영향(影響)에 관한 일고(一考))

  • Yan, Yao zhong
    • Korean Journal of Heritage: History & Science
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    • v.45 no.3
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    • pp.60-79
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    • 2012
  • Environment of ancient Chinese Buddhist temple can be classified to three types such as regional society(鄕村), famous mountain(名山), and urban areas(都市). This made differences in environment where a temple existed and in turn, affected development of Buddhism. And this made another type in relationship between Buddhist temple and a society. This study explains influences which regional society gave on not only Buddhist temple and a monk but also existence and development of Buddhism. When temples are placed in different environmental position, that is, urban areas and regional society, among a social structure, they eventually should adapt to a different society externally and internally. As told in above, ancient Chinese Buddhist temple was located in regional society, famous mountain, and urban areas. Since Eastern Jin and Sixteen Kingdoms, as number of temple much increased, and temples and monks were concentrated on famous mountain, temples in famous mountains and urban areas had developed showing similar aspects each other. But because temples in regional society were influenced a little differently, this study focused on the point. There are four kinds of influences between temples and monks in regional areas. Monks in regional areas had a comparatively close relationship with a society because they came from same area or surrounding areas. Therefore,powers of regional areas restrict influences made by monk group in temple. Second, temples in regional areas shared their joys and sorrows depending on regional economy. Temples in regional areas became a public place for the society and often a market place. In fact, construction and existence of a temple originally became a driving force in regional economy. This is because construction of temple needs artisans and materials and some temples had visitors and included market economy like consumption of incense and candles, though the economic size was large or small. And when regional areas experienced natural disaster or man-made disaster or had poor harvest or economy was in depression, monks left temples and then, temples themselves could not exist. Third, the relationship between temples in regional areas and Buddhists was distinguished from the temples in urban areas and famous mountains. This is because temples in China were places where monks practiced and at the same time, places where general Buddhists worshipped. So there were always a number of Buddhists around the temples. Forth, Buddhism in resional areas was connected to regional Folk beliefs. As a result, Buddhism was spread across the nation, worship with local color often was changed to Buddhist belief or was tinged with Buddhism. While temples in regional areas maintained a close relationship with regional society.they were influenced by the region or gave influences. As a representative example, temples in regional areas showed model behaviors instead of roles of facilities related to various cultures with comparatively advanced level - for example, school, hospital etc. The temples highly affected funerary rites in regional areas. Chinese tombs were mainlymade in regional areas. After death,people living in urban areas were buried in hometown or at least, they were buried in suburbs not urban areas. Temples in regional areas generally participated in funerary rites. Above shows that though most of famous Buddhist temples were located in urban areas not in famous mountains,majority of temples were located in vast regional areas. Through mutual interaction between temples and regional society, the temples in the regional areas were related to Chinese people of over 90% and regional areas became the most important foundation for Buddhism in China. Mutual influences between temples in regional areas and the general public in regions were omnidirectional and spreaded to every aspects of social life in small or large degree. Thus Tombs in temple were widely spreaded across regional areas over time and space. This is enough to explain a close relationship between Buddhist temples and rural society in ancient China.

Development of Analytical Method for Determination of Baicalin, Eleutheroside E, and Ligustilide by LC-MS/MS in Raw Materials of Health Functional Foods (LC-MS/MS를 이용한 건강기능식품 원료 중 바이칼린, 엘레우테로사이드 E, 리구스틸라이드 동시분석법 개발)

  • Keum, Eun Hee;Chung, So Young;Lee, Jin Hee;Kim, Meehye
    • Journal of Food Hygiene and Safety
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    • v.32 no.3
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    • pp.193-198
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    • 2017
  • Scutellaria baicalensis, Eleutherococcus senticosus, and Angelica sinensis have been used as raw materials for health functional foods. This study was conducted to develop a novel method to analyze levels of baicalin (Scutellaria baicalensis), eleutheroside E (Eleutherococcus senticosus), and ligustilide (Angelica sinensis) simultaneously in health functional foods. The methanol extracted samples were analyzed and quantified via liquid chromatography-tandem mass spectrometry (LC-MS/MS) in the positive ion mode and the negative ion mode using multiple reaction monitoring. Standard calibration curves confirmed linearity with the correlation coefficient ($r^2$) of > 0.99 at $100-2000{\mu}g/mL$ concentration range. The limits of detection (LODs) and limits of quantitation (LOQs) were in the range of $13.0{\sim}35.2{\mu}g/L$ and $39.3{\sim}106.7{\mu}g/L$, respectively. The recovery results ranged between 91.4~109.9% at 3 different concentration levels with relative standard deviations (RSDs) less than 5%. The proposed analytical method was characterized with high accuracy and acceptable precision. The new method would be an effective tool to analyze baicalin, eleutheroside E, and ligustilide simultaneously in raw materials of health functional foods.