• Journal of Korea Multimedia Society
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• v.16 no.7
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• pp.829-840
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• 2013

In this paper, we propose a new lung segmentation method for chest x-ray images which can take both global and local properties into account. Firstly, the initial lung segmentation is computed by applying the active shape model (ASM) which keeps the shape of deformable model from the pre-learned model and searches the image boundaries. At the second segmentation stage, we also applied the localizing region-based active contour model (LRACM) for correcting various regional errors in the initial segmentation. Finally, to measure the similarities, we calculated the Dice coefficient of the segmented area using each semiautomatic method with the result of the manually segmented area by a radiologist. The comparison experiments were performed using 5 lung x-ray images. In our experiment, the Dice coefficient with manually segmented area was $95.33%{\pm}0.93%$ for the proposed method. Effective segmentation methods will be essential for the development of computer-aided diagnosis systems for a more accurate early diagnosis and prognosis regarding lung cancer in chest x-ray images.

• Korean Journal of Biological Psychiatry
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• v.18 no.4
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• pp.232-238
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• 2011

Objectives Optimized voxel based morphometry (VBM) has been increasingly applied to investigate differences in the brain morphology between a group of patients with mild cognitive impairment (MCI) and control subjects. Optimized VBM permits comparison of gray matter (GM) volume at voxel-level from the entire brain. The purpose of this study was to assess the regional GM volume change measured by optimized VBM in MCI subjects compared to controls. Methods Twenty patients with MCI and 20 control subjects with normal cognition were recruited for this study. We applied the optimized VBM protocol to the image data including study-specific template and the modulation of the data with the Jacobian determinants. GM volume differences between the MCI subjects and the control subjects and their correlations with the neuropsychological performances were investigated. Results Optimized VBM analysis revealed GM volume reduction in hippocampus, precentral gyrus, insula and parietal operculum in the MCI group compared to the control group (family wise error corrected p < 0.05). Korean version of the Consortium to Establish a Registry for Alzheimer's disease (CERAD-K) word list recall scores were significantly correlated with the GM volumes of hippocampus, precuneus and posterior cingulate in the MCI group (FWE corrected p < 0.05). Conclusions The results confirm previous findings of atrophic changes in medial temporal lobe and parietal lobe in the MCI group and suggest that these abnormalities may be related with cognitive decline and prognosis in patients with MCI.

• Investigative Magnetic Resonance Imaging
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• v.11 no.1
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• pp.1-9
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• 2007

The obstacles for cardiac imaging are motion artifacts due to cardiac motion, respiration, and blood flow, and low signal due to small tissue volume of heart. To overcome these obstacles, fast imaging technique with ECG gating is utilized. Cardiac exam using MRI comprises of morphology, ventricular function, myocardial perfusion, metabolism, and coronary artery morphology. During cardiac morphology evaluation, double and triple inversion recovery techniques are used to depict myocardial fluidity and soft tissue structure such as fat tissue, respectively. By checking the first-pass enhancement of myocardium using contrast-enhanced fast gradient echo technique, myocardial blood flow can be evaluated. In addition, delayed imaging in 10 - 15 minutes can inform myocardial destruction such as chronic myocardial infarction. Ventricular function including regional and global wall motion can be checked by fast gradient echo cine imaging in quantitative way. MRI is acknowledged to be practical for integrated cardiac evaluation technique except coronary angiography. Especially delay imaging is the greatest merit of MRI in myocardial viability evaluation.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.6
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• pp.3061-3067
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• 2013

This paper exemplifies how "Case Study House" (CSH) Program has been reduced as an architectural style rather than an American alternative to European Modernism. CSH Program became less successful than it deserves in the post-war American building market while its contribution to modern domestic architecture is immense and still regarded significant. The Program was succeeded in obtaining attention from the general public for architect-built(custom-built) houses with standardized building parts and simultaneously it also attempted to discover prototyped plans aiming good affordable mass housing at the time of post-war house shortage. Subsequent works nonetheless stay remained in the realm of avant-gardian image-making only to reflect affluent regional life style.

• Proceedings of the KOSOMBE Conference
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• v.1998 no.11
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• pp.281-282
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• 1998

Recently, there has been growing interest in the assessment of physiological parameters on brain perfusion that provide more information than pure morphologic diagnosis. Quantification of parameters that characterize cerebral micro-circulation with magnetic resonance imaging is of great relevance for clinical application. We determine the local tissue concentration by exponential relationship between the relative signal reduction S(t)/$S_0$ and local tissue concentration of contrast material $C_m(t)$ in dynamic susceptibility contrast enhanced MR imaging. And then we made relative regional blood volume map by calculating the area under the measured concentration-time curves $C_m(t)$ during first pass of paramagnetic contrast material as a preliminary step for perfusion map. These images make it possible to compare the rCBV in different brain regions in one individual at a time. We have it in contemplation to obtain arterial and brain signal time curves simultaneously to make absolute rCBV and perfusion (rCBF) map. These maps may provide the method of comparative investigations of different patients having strong variation in AIF.

• Journal of Chest Surgery
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• v.32 no.10
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• pp.910-915
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• 1999

Background: Positron emission tomography(PEFT) using fluorine-18 deoxyglucose(FDG), showing increased FDG uptake and retention in malignant cells, has been proven to be useful in differentiating malignant from benign tissues. We indertook the prospective study to compare the accuracy of the whole-body FDG PET with that of the conventional chest computed tomography(CT) for nodal staging of non-small-cell lung cancers(NSCLC). Material and Method: FDG PET and contrast enhanced CT were performed in 36 patients with potentially resectable NSCLC. Each Imaging study was evaluated independently, and nodal stations were localized according to the AJCC regional lymph nodes mapping system. Extensive lymph node dissection(1101 nodes) of ipsi- and contralateral mediastinal nodal stations was performed at thoracotomy and/or mediastinoscopy. Image findings were compared with the histopathologic staging results and were analyzed with the McNema test(p) and Kappa value(k). Result: The sensitivity, specificity, positive predictive value, and negative predictive value of CT for ipsilateral mediastinal nodal staging were 38%, 68%, 25%, 79%, and 61%, and those of PET were 88%, 71%, 47%, 95%, and 75%(p>0.05, K=0.29). When analyzed by individual nodal group(superior, aortopulmonary window, and inferior), the sensitivity, specificity, positive predictive value, and negative predictive value of CT were 27%, 82%, 22%, 85%, and 73%, and those of PET were 60%, 87%, 92%, and 82%(p<0.05, k=0.27). Conclusion: FDG PET in addition to CT appears to be superior to CT alone for mediastinal staging of non-small cell lung cancers.

• Journal of the Korean Society of Food Culture
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• v.33 no.3
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• pp.217-228
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• 2018

This study aimed to develop unique, local "food tourism" products by finding specialized items that combine tourist attractions, such as folklore or hot springs. Traditional ingredients were analyzed with ancient texts for the methods of research. A brand image was made possible utilizing hot spring lore and other regional stories. The tofu products were produced using local specialty beans. Products, such as tofu residue cake and willow bean tea, were made with the tofu residue. After the products were completed, the sensory test began at the local tourist attraction. Asan City's food tourism product willow tofu was made with beans that were given as compensation for building the Onyang temporary palace according to the Annals of the Joseon Dynasty and the willow tree that appears in Sunshin Lee's anecdotes. After the preference test between normal tofu and willow-extract tofu was conducted to measure the product potential of willow tofu, among the sample extracts, 0.04% of the willow extract showed a significant preference. The hot spring tofu-residue cake was baked using tofu residue and vegetable olive oil to substitute for animal oil, such as butter, or margarine. After the sensory test targeting the adults was conducted, both products displayed significant product potential with average scores above 5.0. Willow tree bark, which has antioxidation and anti-inflammatory effects without a bitter taste or strong smell, was proven to bean appropriate ingredient for leached tea. The nutty flavor of leached tea was enhanced by roasted green kernel black beans and willow tree bark. The sensory test showed that the leached tea and tofu received a high preference rating on both color and flavor.

• The Journal of the Korea Contents Association
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• v.15 no.2
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• pp.208-222
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• 2015

Competition among local governments in a competitive global festival and the festival is going to become the intensify regional strategies as enabled by the improved local image production and has been a symbol of the festival and each municipality is competitive. Is required as a symbol for the symbol can be passed to the consumer in this situation differentiated festive images efficient communication studies on the character. When viewed as a symbolic sign for the character representation of activities for the festival, Can provide a logical framework that is distinct from the idea of a character who relies on intuition and the creative semiotics. In this research paper a semiotic analysis of the character and the character string to enhance communication efficiency concept, Festival effect, we analyzed the correlation of the local culture. Empirical analysis of consumer images, Shared on the basis of empirical results to the consumer means, the paper shows that the influence of each of the other factors is reflected in the character according to the signifier local cultural characteristics and a character region on the concept of a character form culture semiotics interpretation element influences the guidelines of the characters that may be produced.

• Journal of Korean Society of Forest Science
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• v.88 no.1
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• pp.55-62
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• 1999

Successful hosting of mesa-events such as the universiade games usually brings many external changes such as more domestic and foreign travelers, image improvement of the host country and region as well as promotion of the local economy through improving the infrastructure for the contest. This longitudinal study analyzed the effects of the winter universiade games, which were held at Muju in 1997, on the hosting rural area, based upon a multidimensional study. As a result, the inhabitants sensed that hosting the winter universiade games had large-scale investment effects on both the tourism industry and the regional development. On the other hand, hosting this kind of event was not quite successful in terms of activating the local economy, and the environment of Togyusan National Park was harmed.

• Korean Institute of Interior Design Journal
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• v.23 no.1
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• pp.172-180
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• 2014

A railway station appears in the form of multi-use station building where cultural and commercial elements such as shopping and leisure are mixed, getting out of simple space configuration oriented to the space for station work, where a passenger stays for a little while. Now, a railway station is a place expanded to the inside of city, and builds a relationship with urban fabric, and therefore it should receive the social change in the time together with the surrounding infrastructure, and should inevitably form the urban environment. And it should become the 'Place' so as to be capable of playing a role of buffer and a role of regional gateway landmark by making users included in the inside through various uses with regard to the dispersed urban connection. Hence, this study is intended to examine the planning through the place branding of railway station. In the method of research, the characteristics that place branding had was investigated, and an analysis was made on the basis of 10 place branding strategic elements and 6 railway design guidelines. And it was intended to set a direction in which the existing place branding strategy could be applied to the railway station, and was intended to derive the place branding planning strategic elements of railway station. Hence, the planning can be classified into the following 5 kinds in connection with railway station. First, identity should be embodied through the strategy of constructing the symbolic image of railway station. Second, a role of mediating variously approaching flows in the city should be played. Third, the spatial layout of railway station, which can increase the efficiency of use, should be arranged. Fourth, special characteristics should be intensified through creative storytelling that stimulates emotion. Fifth, an organic change is gradually necessary for sustainability. These planning elements should be applied in harmonious combination. Therefore, a new railway station can be maded by building identity and placeness and by giving the value through these planning directions in the future.