• 디자인학연구
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• 제18권3호
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• pp.55-62
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• 2005

최근 세계 경제의 개방화 및 우기나라 지방분권화로 인해 지역산업 경제 발전을 위한 디자인산업 육성에 대한 끊임없는 노력과 투자가 요구되고 있다. 최근 중국과 동남아시아 국가와의 제품 가격경쟁력에서 밀리고 있는 국내 상품은 디자인의 독창성이나 제품의 다양성, 그리고 마케팅 분야의 관심 확대를 통해 제품의 브랜드 이미지 구축과 국제사회에서 소비자들의 호응을 얻어야 한다. 따라서 디자인 산업은 제품의 차별화 및 고부가가치화를 통해 국내 산업의 경쟁력을 강화할 수 있는 중요한 수단이 되고 있다. 우리나라 디자인 산업 환경의 문제점으로는, 아직까지도 많은 제조 생산업 분야에서는 상품 개발 및 마케팅 전략 수준이 낮은 실정이며, 새로운 디자인 개발을 위한 투자를 기피하고 있다는 점이다. 또한 유능한 디자이너의 경험이나 기술 축적을 위한 인적 기반 형성에 한계가 있고, 디자인 산업 보호제도 및 정책의 실효성 부재에 문제가 있다. 따라서, 대구, 경북지역의 사회적, 문화적 환경에 부응하는 디자인 산업 활성화를 위한 구체적인 전략으로는 디자인 전문인력 인프라 구축, 디자인 연구개발의 체계화, 디자인 관련 정보의 공유, 디자인 전문회사의 확대 등을 위한 정책 마련이 이루어져야 할 것이다. 그러므로 디자인 중심의 인적, 물적, 지적 인프라 구축을 통한 디자인 기반을 확충하여 지역 혁신 디자인 클러스터화를 통한 대구 경북지역의 경제 활성화에 도움이 되도록 해야 할 것이다.

• Archives of Pharmacal Research
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• 제10권1호
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• pp.42-49
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• 1987

This study is to evaluate the potential use of aclarubicin-loaded gelatin microspheres as an intravascular biodegradable drug delivery system for the regional cancer therapy. The diameter of the microspheres prepared by water in oil emulsion polymerization could be controlled by adjusting the stirring rate in the range of 10-50 $\mu$m : D(in $\mu$m) = -73.8 log (rpm) + 262.7. The addition of proteolytic enzyme increased the in vitro aclarubicin release but it did not change the amount of the initial burst release which reached about 45%. Microspheres injected intravenously into the mouse tail vein embolized only to the lung when observed by fluorescence microscopy. From histological examination following injection of gelatin microspheres into mouse femoral muscle, mild inflammation was observed from the appearance of neutrophils after 2 days and rapid repair process was confirmed thereafter. Biodegradation process of gelatin microspheres lodged on the pulmonary capillary bed was followed up by microscopic observation; degradation was taking place by about 36 hrs, followed by severe damage on the spheerical shape and microspheres was no longer found 10 days after injection.

• Archives of Plastic Surgery
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• 제42권4호
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• pp.475-477
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• 2015

We report the case of a 33-year-old male who presented with a malignant melanoma on his anterior chest wall. The lesion was only found in the red ink pigment of the tattoo, as were several in-transit dermal metastases. Possible explanations include a pre-existing lesion which was seeded with red ink or the possibility of the red ink causing an inflammatory reaction leading to malignant transformation. This is the first reported case of a melanoma developing in the red ink pigment of a multi-colored tattoo.

• 디자인학연구
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• 제15권4호
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• pp.295-306
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• 2002

34년만에 본격적인 지방화 시대가 열린 이후 개성 있는 도시 이미지 만들기 작업이 전개되고 있다. 지방화시대의 개방으로 각각의 지역은 유니크한 특성과 자율성을 형성하여 그를 바탕으로 지역의 삶의 질을 향상시키는데 필요한 지역발전 전략을 수립하여 추진하고 있다. 즉 지역고유의 특성을 바탕으로 유니크한 아이덴티티를 창조하면서 미적인 경영을 지향하는 경영전략을 가지고 지방화 시대에 대응하는 것이다. 본 연구에서는 전라남도 순천시의 CI 연구 사례를 중심으로 자치단체 CI개발에 관해 다루었다. 순천시는 남도 관광의 보고인 송광사, 선암사, 낙안읍성, 순천만등 천혜의 관광자원을 가지고 있다. 시민들의 자긍심과 애향심을 고취시키고 외부 관광객들에게 순천시만의 개성 있는 이미지를 형성할 수 있도록 CI 프로그램을 연구 개발하였다. 이와 관련하여 노출 빈도가 높은 디자인 요소들을 중심으로 순천시의 이미지를 시각화하였다.

• 대한두개안면성형외과학회지
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• 제20권6호
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• pp.401-404
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• 2019

Merkel cell carcinoma (MCC) is a relatively rare and aggressive cutaneous neuroendocrine malignancy. It is characterized by high rates of recurrence and metastasis, both to regional lymph nodes and to distant locations. Its characteristic clinical manifestation is a single, painless, hard, erythematous nodule on a sun-exposed area, particularly in older men. Surgical management of both the primary site and the sentinel lymph node is the standard of care. In this article, we describe the diagnosis and treatment of a case of MCC in the left cheek.

• Archives of Plastic Surgery
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• 제40권3호
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• pp.263-266
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• 2013

Bleeding, is one of the most common postoperative complications after palatoplasty in patients with cleft palate. The purpose of this article is to present our experience using a Foley catheter balloon for perioperative palatoplasty bleeding management. A retrospective data analysis was performed for all cases of palatoplasty performed by the author from 1999 to 2012 that experienced postoperative hemorrhage. These patients were managed by utilizing posterior nasal compression with a Foley catheter balloon for the period 2006 to 2012. We have compared two methods (we use before 2006 the reoperative method) with regards to the later development of palatal fistulae and cases with reoperative hemostasis. The study found no statistically significant differences between the conventional and proposed method in relation to the development of palatal fistulae (P=0.7). These findings suggest that nasal packing using a Foley balloon is a safe and effective method for postoperative bleeding control after palatoplasty in patients with cleft palate.

• 디자인학연구
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• 제3권1호
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• pp.83-93
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• 1990

The constant evolution of society, culture and scientific technology, coupled with changes in life style and behavioral patterns, has led mankind to peroeive diverse needs for space. Particularly, the rapid structural change in the field of marketing has entailed changes in techinques for construction and presentation of space for an improved marketing environment. To satisfy such new, diverse needs for space, interior designers will have to redefine the "mankind and environmen( concept and examine their design methodology anew. The question of how to design available space for a certain purpose will remain a daunting task for designers in the future, as it has been in the past. In the pursuit of convenience and conformity to mankind's surroundings, every nation has, in common with other nations, basic design elements, design skills and other factors. In designing camercial space in a particular region, it is essential, however, to have a proper understanding of the social economic and cultural context indigenous to that region, as well as the impact on environmental and ecological change and marketing strategy. This study discusses design metholdology for the comming camercial space on the basis of the space concept and current status in Korea, with major emphasis on Korea's regional characteristics.

• 한국농림기상학회:학술대회논문집
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• 한국농림기상학회 2001년도 춘계 학술발표논문집
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• pp.43-48
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• 2001

Many applications in the areas of agricultural, hydrological and environmental resource management require data over very large areas and with a high imaging frequency - monitoring crop growth, water stress, seasonal wetland flooding and natural vegetation development. This precludes the use of fine resolution data (Landsat, Spot) on the grounds of cost, accessibility and low imaging frequency. Meteorological satellites have the potential to fill this need, given their very wide spatial coverage, and high repeat imaging. The Remote Sensing Unit (RSU) at the Zambia Meteorological Department routinely receives, processes and archives imagery from both Meteosat and NOAA AVHRR satellites. Here I wish to present some examples of applications of these data sets that arise from the RSU work - relationships between rainfall and vegetation development as assessed by satellite, derived information and seasonal patterns of flooding in the Barotse floodplain and the Kafue flats. I also wish to outline ways in which a more widespread use of this data by the Zambian institutions canbe achieved.

• Archives of Pharmacal Research
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• 제24권2호
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• pp.105-108
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• 2001

$\alpha$-Benzoyloxypaeoniflorin (1), a new antioxidant monoterpene $\alpha$-glycoside anomer was isolated from Paeonia suffruticosa along with known compounds, $\beta$-benzoyloxypaeoniflorin (2), paeonolide, paeoniflorin and mudanpioside H. The structure of 1 has been determined by comparing spectral data with those of $\beta$-Benzoyloxypaeoniflorin(2). Compound 1 exhibited moderately potent radical scavenging activity on DPPH radical.

• Archives of Pharmacal Research
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• 제26권10호
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• pp.796-799
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• 2003

Two known farnesylacetone derivatives (1 and 2) were isolated from the Korean brown alga Sargassum sagamianum off Jeju Island, Korea. Compounds 1 and 2 were identified as (5E,10Z)-6, 10, 14-trimethylpentadeca-5, 10-dien-2, 12-dione and (5E,9E,13E)-6, 10,4-trimethylpentadeca-5,9,13-trien-2,12-dione, respectively, by comparison with the literature data. Compounds 1 and 2 showed moderate acetylcholinesterase and butyrylcholinesterase inhibitory activities with $IC_{50}$ values of 65.0∼48.0 and 34.0∼23.0 $\muM$, respectively.