• Genomics & Informatics
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• 제17권4호
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• pp.46.1-46.7
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• 2019

The implications of germline de novo variants (DNVs) in diseases are well documented. Despite extensive research, inconsistencies between studies remain a challenge, and the distribution and genetic characteristics of DNVs need to be precisely evaluated. To address this issue at the whole-genome scale, a large number of DNVs identified from the whole-genome sequencing of 1,902 healthy trios (i.e., parents and progeny) from the Simons Foundation for Autism Research Initiative study and 20 healthy Korean trios were analyzed. These apparently nonpathogenic DNVs were enriched in functional elements of the genome but relatively depleted in regions of common copy number variants, implying their potential function as triggers of evolution even in healthy groups. No strong mutational hotspots were identified. The pathogenicity of the DNVs was not strongly elevated, reflecting the health status of the cohort. The mutational signatures were consistent with previous studies. This study will serve as a reference for future DNV studies.

• 한국경영과학회:학술대회논문집
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• 대한산업공학회/한국경영과학회 1993년도 춘계공동학술대회 발표논문 및 초록집; 계명대학교, 대구; 30 Apr.-1 May 1993
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• pp.6-15
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• 1993

A generalization of one machine maximum lateness minimization problem is considered. There are one achine with controllable speed and n weighting jobs $J_{j}$, j=1, 2, ..., n with ambiguous duedates. Introducing fuzzy formulation, a membership function of the duedate associated with each job $J_{j}$, which describes the satisfaction level with respect to completion time of $J_{j}$. Thus the duedates are not constants as in conventional scheduling problems but decision variables reflecting the fuzzy circumstance of the job completing. We develop the polynomial time algorithm to find an optimal schedule and jobwise machine speeds, and to minimize the total sum of costs associated with jobwise machine speeds and dissatisfaction with respect to completion times of weighting jobs. jobs.

• 산업공학
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• 제12권4호
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• pp.635-642
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• 1999

Recently, business application vendors have responded to customer demand with several technological and organizational changes for reflecting network-oriented process flow with electronic communication and expanding their market. In organizational changes. Vendors are adding new functionality to their core offerings through mergers and acquisitions, or by partnering with front-office operation and SCM vendors. And technological changes are embracing the development of component-based application and middleware technology to be possible with integration of their function modules. We will present the design and development process of component-based SCM system to be integrated with heterogeneous ERP under implementation. Especially, we survey and analyze the technology related with CBD(Component-Based Development) to be adapted this research - component's design and methodology, the interface for component integration, middleware's development methodology of Enterprise Middleware vendo to bundle various types of middleware into a single package product with easy-to-use interface.

• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2017년도 추계학술발표대회
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• pp.462-463
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• 2017

Although the mirror has been used for a long time primarily for personal purposes, such as adornment by reflecting feature of mirror, it can also be used to expand from its legacy function to safety and lots of unpredictable applications. However, the mirror can be used as an information or investigation base, it is subject to human beings in the private region, objects and private purpose in the public and industrial fields. This paper suggests the wide usage of mirror equipped with smart technology, considering current Korea domestic regulation by law.

• Journal of Electrical Engineering and Technology
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• 제10권4호
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• pp.1830-1835
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• 2015

In this paper, we propose an algorithm for the automatic registration of two rigid parts using multiple 3D sensor systems on a robot. Four sets of structured laser stripe system consisted of a camera and a visible laser stripe is used for the acquisition of 3D information. Detailed procedures including extrinsic calibration among four 3D sensor systems and hand/eye calibration of 3D sensing system on robot arm are presented. We find a best pose using search-based pose estimation algorithm where cost function is proposed by reflecting geometric constraints between sensor systems and target objects. A pose with minimum gap and height difference is found by greedy search. Experimental result using demo system shows the robustness and feasibility of the proposed algorithm.

• Journal of Electrical Engineering and Technology
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• 제9권6호
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• pp.1843-1850
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• 2014

In this paper, we investigate a group building based power consumption scheduling to minimize the electricity cost. We consider the demand shift to reduce the peak load and suggest the compensation function reflecting the relationship between the change of the building demand and the occupants' comfort. Using that, the electricity cost minimization problem satisfied the convexity is formulated, and the optimal power consumption scheduling algorithm is proposed based on the iterative method. Extensive simulations show that the proposed algorithm achieves the group management gain compared to the individual building operation by increasing the degree of freedom for the operation.

• 전기학회논문지
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• 제63권9호
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• pp.1192-1198
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• 2014

With an increase in the penetration of offshore wind farm, the need of an accurate economic evaluation of offshore wind farm has become crucial. This paper presents an economic evaluation method of offshore wind farm in Korea reflecting the cost of offshore wind farm infrastructure (offshore substation, submarine cable and foundation) in its cost model. Each cost of offshore substation, submarine cable, and foundation is represented as a function of installed capacity, distance to shore, and water level, respectively. We have applied the method to the case study of offshore in Jeju Island and analyzed the economics under various conditions. The results show that the distance to shore is of importance in economics of offshore wind farm.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2005년도 제36회 하계학술대회 논문집 A
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• pp.745-747
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• 2005

After restructuring electricity industry, national long term electricity plans moved to "Basic plan of electricity supply and demand" from "Long term power development plan". The main point is a change of path from plan of power development at national level to plan of electricity supply and demand at company level. A proposal by generation company is surveyed and reflected to the basic plan of electricity supply and demand. The second plan shows over 40% reserves in result of the proposals. It is the time to evaluating the proposal which covers market function in the basic plan of electricity supply and demand at the stage of market change. This research presents the need of evaluation of proposals and the methods of evaluation. Also it presents the alternative planning procedure to reflecting the evaluation methods.

• 한국주거학회:학술대회논문집
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• 한국주거학회 2008년 추계학술발표대회 논문집
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• pp.407-412
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• 2008

The purpose of this study is to find out the preference and the opinion of feminine seniors on the life support appliances(video phone, medication dispenser, activity monitor and sleep monitor). The appliances may be improved reflecting the result of the preferred functions and designs. The respondents were 141 feminine seniors of 65 years & older, living in Ulsan city or Cheongju city, Korea. Following is the result. 1) All the responses answered that the medication dispenser, video phone and activity monitor, sleep monitor are useful appliances. 2) All the seniors expressed prefer to function of the appliances, and were highly concerned about the price, safety and convenience. 3)The preferred designs were (1) white or red standing medication dispenser,(2) wall-mounted video phone working by voice, (3) metal activity monitor sensor like white or yellow bracelet.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2001년도 ICCAS
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• pp.99.3-99
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• 2001

In fluorescence mode confocal scanning microscope, level of detected signal is very low. In object scanning type confocal scanning microscope, the additional optical system with objective lens and plane mirror was proposed to increase signal intensity, but there was none for beam scanning type confocal scanning microscope. We propose reflecting optical systems which improve signal intensity in beam scanning type confocal scanning microscope. We choose one of the proposed optical systems and design the optical system, i.e., select optical components and assign distances between the selected components. To design the optical system, we use finite ray tracing method and make cost function to be minimized.