• Title/Summary/Keyword: reference range

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Evaluation of Norudia® HbA1c Kit for Glycohemoglobin Assay (당화혈색소 측정을 위한 Norudia® HbA1c 키트의 평가)

  • Hong, Seung-Bok;Kim, Eun-Joong
    • Korean Journal of Clinical Laboratory Science
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    • v.41 no.1
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    • pp.37-41
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    • 2009
  • Measurement of hemoglobin A1c is used as an objective indicator of long-term blood glucose control in diabetic patients. We evaluated recently introduced Norudia$^{(R)}$ HbA1c (Daiichi Pure Chemical Co. Ltd, Tokyo, Japan) test reagent using enzyme method for HbA1c assay. Linearity, precision and correlation with VARIANT$^{TM}$ II Turbo HbA1c analyzer (BIO-RAD, Hercules, CA, USA) were evaluated. The reference range was determined from 201 healthy subjects. The Norudia$^{(R)}$ HbA1c test reagent was founded to be linear in a range of 5.6% to 14.0% ($r^2=0.9885$). The within-run and between-day precision were 0.954% and 1.03% for low level (HbA1c 5.24%), 0.67% and 1.28% for high level (HbA1c 9.01%), respectively. Comparison study between Norudia$^{(R)}$ HbA1c test reagent and VARIANT$^{TM}$ II Turbo showed good correlation with a slope of 1.0489. an intercept at -0.9717, and coefficient of correlation was 0.9907. The reference range of HbA1c obtained from this reagent was 4.07-5.50%. The Norudia$^{(R)}$ HbA1c test reagent showed good linearity, precision and correlation with HbA1c analyzer with HPLC method. In addition, the exclusive analyzer is not required for assay and then this kit may be useful for HbA1c assay in clinical laboratory.

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Performance Analysis of Adaptive Bandwidth PLL According to Board Design (보드 설계에 따른 Adaptive Bandwidth PLL의 성능 분석)

  • Son, Young-Sang;Wee, Jae-Kyung
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.45 no.4
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    • pp.146-153
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    • 2008
  • In this paper, a integrated phase-locked loop(PLL) as a clock multiphase generator for a high speed serial link is designed. The designed PLL keeps the same bandwidth and damping factor by using programmable current mirror in the whole operation frequency range. Also, the close-loop transfer function and VCO's phase-noise transfer function of the designed PLL are obtained with circuit netlists. The self impedance on board-mounted chip is calculated according to sizes and positions of decoupling capacitors. Especially, the detailed self-impedance analysis is carried out between frequency ranges represented the maximum gain in the close-loop transfer function and the maximum gain in the VCO's phase noise transfer function. We shows PLL's jitter characteristics by decoupling capacitor's sizes and positions from this result. The designed PLL has the wide operating range of 0.4GHz to 2GHz in operating voltage of 1.8V and it is designed 0.18-um CMOS process. The reference clock is 100MHz and PLL power consumption is 17.28mW in 1.2GHz.

Fabrication of Solid Electrolyte Oxygen Sensors Using $CaF_{2}$ and their Characteristics ($CaF_{2}$를 이용한 고체전해질 산소센서의 제조및 그 특성)

  • Lee, Jae-Hyun;Lee, Duk-Dong
    • Journal of Sensor Science and Technology
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    • v.3 no.2
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    • pp.40-49
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    • 1994
  • Potentiometric cell oxygen sensors using $CaF_{2}$ were fabricated for monitering the oxygen partial pressure in the low temperature range ($300^{\circ}C{\sim}$500^{\circ}C). The disk type oxygen sensors consist of a reference electrode: Air($O_{2}:21%$)|Pt, a solid electrolyte $CaF_{2}$, and a sensing metel Pt electrode. And the change in open circuit emf of the disk type cell was about 45mV for the oxygen concentration range, $0.1%{\sim}10%$, at the cell temperature of $400^{\circ}C$. Also, the reference electrode incorporated type sensor showed the change of 40mV for 0.1% to 10% oxygen partial pressure range.

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A Study on the DGPS Radiobeacon Propagation Measurement of Domestic Ferry Lines (우리나라 선박 항로구간의 DGPS 전파 특성에 관한 연구)

  • Jeon, Joong-Sung;Lee, Seo-Jeong
    • Journal of Advanced Marine Engineering and Technology
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    • v.35 no.4
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    • pp.491-499
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    • 2011
  • Starting with maritime DGPS base stations of Palmido, Ochongdo which have been operated since 1999, truly our nation has become the most powerful country possessed with total of 17 DGNSS base stations in the field of DGNSS operation infrastructure. This paper examines into the country's DGNSS services as measuring the service range of the maritime DGPS base stations in the domestic ferry lines which sections are from Jeju to Incheon, from Busan to Jeju, from Jeju to Nokdong, the propagation characteristics of the radio waves of 300 kHz bands on sea and land path. As a result of identifying the service range of the DGPS in the sea routes of the southern sea and the western sea, the measured results of the DGPS signals are confirmed more than 100 NM(recommended service range). It can be possible to practical use the position information, which is safe navigation and various marine traffic management systems. It will be useful an expansion of maritime DGPS reference station in the near future.

The Research on the Heated CWDM(Coarse Wavelength Division Multiplexing) Optical Transceiver for the Wavelength Compensation at the Low Temperature (저온 파장 보상을 위한 히터 내장형 CWDM(Coarse Wavelength Division Multiplexing) 광 송수신기에 관한 연구)

  • Kwon, Yoon-Koo;Park, Kyoung-Su;Lee, Ji-Hyun;Kim, Chang-Bong
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.13 no.3
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    • pp.1263-1269
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    • 2012
  • This paper is the research on the heated CWDM optical transmitter for the wavelength compensation at the low temperature. In general, the wavelength deviation of DFB laser is around 0.1 nm/C. The wavelength of DFB laser shifts to longer(shorter) wavelength according to the temperature increase(decrease). Typical CWDM optical communication network has 20 nm channel spacing from reference center wavelength per each channel. There is some limitation problem in the range of operating temperature due to the channel interference. For solving the limited temperature range problem, especially at the low temperature, we use the heater on the DFB laser. As a result, we could realize the CWDM optical transmitter to meet +/-6.5 nm from reference center wavelength in the range of temperature at $-40{\sim}+85^{\circ}C$, which is applicable to the industrial field.

Renal Glucosuria in a Dog (개에서 신성 당뇨 일례)

  • Kang Ji-houn;Cho Min-haeng;Kim Min-jun;Chang Dong-woo;Na Ki-jeong;Yang Mhan-Pyo
    • Journal of Veterinary Clinics
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    • v.22 no.4
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    • pp.420-423
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    • 2005
  • A 2-year-old 16-kg, intact female lindo was presented with weight loss and poor hair coat. Abnormal serum biochemical values included mild hypokalemia (3.9 mmol/L, reference range 4.37 to 5.35 mmol/L) and mild hyperglycemia (124 mg/dl, reference range 65 to 118 mg/dl). in the complete blood count and diagnostic imaging examination, abnormal changes wer not seen. The analysis of urine sample obtained from cystocentesis revealed glucosuria (> 100 mg/dl) and mild proteinuria. Repeated analysis after admission showed persistent glucosuria and hypokalemia. But blood glucose values did not exceed the renal threshold fur glucose reabsorption. To differentiate cause of the glucosuria, the glucose tolerance test and the low-dosage dexamethasone suppression test were indicated. Results of both tests were normal. In addition, the serum total thyroxine $(T_4)$ value was within normal range. The arterial blood gas analysis showed no remarkable changes. The fractional reabsorption rates of amino acids and phosphorus were calculated above $97\%$. Based on these findings, the dog was diagnosed as renal glucosuria due to proximal renal tubular dysfunction. But this persistent renal glucosuria with hypokalemia may be the initial sign of Fanconi's syndrome or proximal renal tubular acidosis.

Portable thermocouple thermometer on the nonlinearity compensation (비선형 특성을 보정한 휴대용 열전대 온도계)

  • Kim, Seong-Kuk;Song, Jae-Won
    • Journal of Sensor Science and Technology
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    • v.4 no.1
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    • pp.21-28
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    • 1995
  • A portable type K thermocouple thermometer is designed and fabricated to compensate the linearity to the high temperature $1000^{\circ}C$. The problems to be solved, which use a thermocouple thermometer are the compensation of the nonlinearity characters and reference compensation. The nonlinear character of the thermocouple is compensated, using an EPROM, and the reference compensation done using an IC AD595A. Before this compensation, there was the maximum error of $23.6^{\circ}C$(2.69%) at $876^{\circ}C$. However the results measured by the portable type K thermocouple thermometer fabricated show the character of the error of ${\pm}2^{\circ}C$(0.2%) in the range of the total temperature. This character satisfies the precision specifications of the type K thermal sensors in the range available $1000^{\circ}C$, which can be measured by the use of type K thermocouples. Therefore the portable type K thermocouple thermometer fabricated can be comparatively exactly used for the wide range of temperature of interest. Then this technique of compensating the nonlinear characters can be applied to the other kinds of thermal sensor compensation.

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Development of Highly Efficient Underwater Loudspeaker for Attracting and Threatening Fish (어류의 유집과 구집용 수중 스피커 개발에 관한 연구)

  • Kim Chun-Duck;Lee Chai-Bong
    • The Journal of the Acoustical Society of Korea
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    • v.25 no.1
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    • pp.7-13
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    • 2006
  • Fisheries policy change from catching to farming requires more intensive consideration for aquaculture industry. The oceanic farm is a desirable cost effective aquaculture method. However. in odor to gather fish in the oceanic farm, eating sound or any attracting sound should be radiated through underwater loudspeaker. In this Paper, it has been found in literature that the frequency range responding to fish is about 16Hz to 13kHz but sensitive frequency range is about 150Hz to 2kHz and sound pressure level is about 100dB to 150dB reference $1{\mu}Pa$. Therefore, frequency range and output sound level of designed underwater loudspeaker has been specified as 150Hz to 3kHz and 100dB to 145dB reference $1{\mu}bar$. respectively To verify the stability and the endurance to the pressure of 40m water depth, manufactured underwater loudspeaker was examined before sea trial in manufactured water pressure tank which gives a maximum of 10 atmospheric Pressure. We experimented on acoustic characteristic with manufactured underwater loudspeaker under water depth of 10m.

A fast decoding algorithm using data dependence in fractal image (프래탈 영상에서 데이타 의존성을 이용한 고속 복호화 알고리즘)

  • 류권열;정태일;강경원;권기룡;문광석
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.22 no.10
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    • pp.2091-2101
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    • 1997
  • Conventional method for fractal image decoding requires high-degree computational complexity in decoding propocess, because of iterated contractive transformations applied to whole range blocks. In this paper, we propose a fast decoding algorithm of fractal image using data depence in order to reduce computational complexity for iterated contractive transformations. Range of reconstruction image is divided into a region referenced with domain, called referenced range, and a region without reference to domain, called unreferenced range. The referenced range is converged with iterated contractive transformations, and the unreferenced range can be decoded by convergence of the referenced range. Thus the unreferenced range is called data dependence region. We show that the data dependence region can be deconded by one transformation when the referenced range is converged. Consequently, the proposed method reduces computational complexity in decoding process by executing iterated contractive transformations for the referenced range only.

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Historical Control Data from 4-week Repeated Toxicity Studies in Crj:CD (SD) Rats

  • Lee, Jung-Min;Lee, Min-Ah;Do, Hyeon-Nam;Bae, Re-Ji-Na;Lee, Mi-Ju;Kim, Myoung-Jun;Jang, Ho-Song;Park, Sun-Hee;Lee, Hye-Yeong;Kang, Jin-Seok;Kang, Jong-Koo
    • Biomedical Science Letters
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    • v.18 no.3
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    • pp.268-275
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    • 2012
  • Reference ranges of standard experimental parameters are useful for comparisons in toxicology. The aim of this study was to collect data from 4-week repeated toxicity studies in Crl:CD (SD) rats, a strain widely used for toxicity and efficacy research, for establishing domestic reference values. Data on body weight, food consumption; urinalysis, hematological, and blood biochemical parameters; and organ weights were collected from 16 toxicity studies in 220 Crl:CD (SD) rats (110 males and 110 females). The studies had been performed at a single testing facility over the last 3 years and involved animals sourced from a single breeder. The findings were collated as means, standard deviations, percentages, and ranges. Urine volume, uterus weight, eosinophil, and basophil counts, and triglyceride, total bilirubin, and gammaglutamyl transpeptidase levels showed standard deviations of 30% or more. These historical control data would help to interpret the effects of test substances in routine toxicity and efficacy studies.