• Journal of Sensor Science and Technology
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• v.20 no.5
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• pp.357-362
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• 2011

This paper demonstrates a novel electrodynamic technique to remove particles from the wall of microchannels. Dielectrohporesis(DEP) is generated by applying alternating electric potentials to the interdigitated electrodes integrated at the bottom of the micro-channel. The proposed technique is applied to a general microfluidic channel as a feasibility test. To examine the wall loss reduction efficiency, 10 ${\mu}m$ diameter Polystyrene latexes(PSL) were supplied to the inlet of the device. Then, the concentration of collected particles through devices was measured. In the experiment for 10 ${\mu}m$ diameter PSL particles, the concentration of the injected particles was $174.25{\times}10^4$ particles/ml. However, the concentration of collected particles at the outlet was $52.25{\times}10^4$ particles/ml. Only 30 % of particles had arrived at the outlet and 70 % of particles had adhered to the wall of the microfluidic channel. By applying alternating electric potentials from 0 to 20 $V_{pp}$ at 3 MHz, the concentration of injected particles was 135.00${\times}10^4$ particles/ml, the concentration of collected particles was increased as $105.25{\times}10^4$ particles/ml at 20 $V_{pp}$ at the outlet. When the electric potential was 20 $V_{pp}$, the particle loss was decreased by 39 % (initial loss: 70 %, loss at 20 Vpp: 31 %) with 10 ${\mu}m$ particle. The particle loss was decreased along to the incensement of electric potentials and the enlargement of the diameter of particles. According to these measured results, it was confirmed that the proposal of using DEP technique could be a good candidate for particle loss reduction in micro-particle processing chip application. Moreover, it is expected that the proposed technique could enhance performance of microfluidic and biochip devices.

• Journal of Audiology & Otology
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• v.24 no.1
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• pp.10-16
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• 2020

Background and Objectives:The blockage of adenosine receptors by caffeine changes the levels of neurotransmitters. These receptors are present in all parts of the body, including the auditory and vestibular systems. This study aimed to evaluate the effect of caffeine on evoked potentials using auditory brainstem responses (ABRs) and cervical vestibular-evoked myogenic potentials (cVEMPs) in a double-blind placebo-controlled study. Subjects and Methods: Forty individuals (20 females and 20 males; aged 18-25 years) were randomly assigned to two groups: the test group (consuming 3 mg/kg pure caffeine powder with little sugar and dry milk in 100 mL of water), and the placebo group (consuming only sugar and dry milk in 100 mL water as placebo). The cVEMPs and ABRs were recorded before and after caffeine or placebo intake. Results: A significant difference was observed in the absolute latencies of I and III (p<0.010), and V (p<0.001) and in the inter-peak latencies of III-V and I-V (p<0.001) of ABRs wave. In contrast, no significant difference was found in cVEMP parameters (P13 and N23 latency, threshold, P13-N23 amplitude, and amplitude ratio). The mean amplitudes of P13-N23 showed an increase after caffeine ingestion. However, this was not significant compared with the placebo group (p>0.050). Conclusions: It seems that the extent of caffeine's effects varies for differently evoked potentials. Latency reduction in ABRs indicates that caffeine improves transmission in the central brain auditory pathways. However, different effects of caffeine on auditory- and vestibular-evoked potentials could be attributed to the differences in sensitivities of the ABR and cVEMP tests.

• Korean Journal of Audiology
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• v.24 no.1
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• pp.10-16
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• 2020

Background and Objectives:The blockage of adenosine receptors by caffeine changes the levels of neurotransmitters. These receptors are present in all parts of the body, including the auditory and vestibular systems. This study aimed to evaluate the effect of caffeine on evoked potentials using auditory brainstem responses (ABRs) and cervical vestibular-evoked myogenic potentials (cVEMPs) in a double-blind placebo-controlled study. Subjects and Methods: Forty individuals (20 females and 20 males; aged 18-25 years) were randomly assigned to two groups: the test group (consuming 3 mg/kg pure caffeine powder with little sugar and dry milk in 100 mL of water), and the placebo group (consuming only sugar and dry milk in 100 mL water as placebo). The cVEMPs and ABRs were recorded before and after caffeine or placebo intake. Results: A significant difference was observed in the absolute latencies of I and III (p<0.010), and V (p<0.001) and in the inter-peak latencies of III-V and I-V (p<0.001) of ABRs wave. In contrast, no significant difference was found in cVEMP parameters (P13 and N23 latency, threshold, P13-N23 amplitude, and amplitude ratio). The mean amplitudes of P13-N23 showed an increase after caffeine ingestion. However, this was not significant compared with the placebo group (p>0.050). Conclusions: It seems that the extent of caffeine's effects varies for differently evoked potentials. Latency reduction in ABRs indicates that caffeine improves transmission in the central brain auditory pathways. However, different effects of caffeine on auditory- and vestibular-evoked potentials could be attributed to the differences in sensitivities of the ABR and cVEMP tests.

• Proceedings of the Korean Radioactive Waste Society Conference
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• 2004.06a
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• pp.268-277
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• 2004

process (ACP), electrochemical properties of high heat-generating alkali and alkali earth oxides in molten salt were measured and the behavior of those elements were analyzed. The reduction potentials of Cs, Sr, and Ba in a molten LiCl-$Li_2O$ system were more cathodic than that of Li and closely located one another. Thus, it is expected that the alkali and alkali earth would not hinder the reaction mechanism which is via lithium reduction. Alkali and alkali earth metals are likely to recycle into molten salt when the process is operated beyond metal reduction potentials and the effect of electric current on the mass transport is also determined by measuring the metal concentrations in the molten salt phase at different current conditions.

• Archives of Pharmacal Research
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• v.2 no.2
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• pp.111-114
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• 1979

Diazepam was investigated in aqueous buffer media using pulsed rotation voltammetry. The dependence of half-wave potentials on pH indicated a two proton involvement in a two electron transfer reduction in the pH range 3-10. Dizaepam at micromolar concentration levels may be determined by measurement of the limiting difference current.

• Bulletin of the Korean Chemical Society
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• v.19 no.2
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• pp.183-188
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• 1998

Incorporation of metalloporphyrins into polypyrrole (PPy) film was achieved either by electropolymerization of pyrrole in the presence of metal-tetra(sulfonatophenyl)porphyrin anion (MTSPP, M=Co, Fe) or by metalizing hydrogenated tetra(4-sulfonatophenyl)porphyrin anion (H2TSPP) doped into PPy through ion-exchange. Electrochemical reduction of oxygen on the PPy doped with metallo porphyrin (PPy-MTSPP) was studied in acidic and basic solutions. Oxygen reduction on PPy-MTSPP electrodes appeared to proceed through a 4-electron pathway as well as a 2-electron path. In acidic solutions, the overpotential for O2 reduction on PPy-CoTSPP electrode was smaller than that on gold by about 0.2 V. In basic solutions the overpotential of the PPy-CoTSPP electrode in the activation range was close to those of Au and Pt. The limiting current was close to that of Au. However, polypyrrole doped with cobalt-tetra(sulfonatophenyl)porphyrin anion (PPy-CoTSPP) or with iron-tetra(sulfonatophenyl)porphyrin anion (PPy-FeTSPP) was found to have limited potential windows at high temperatures (above 50 ℃), and hence the electrode could not be held at the oxygen reduction potentials in basic solutions (pH 13) without degradation of the polymer.

• Annals of Clinical Neurophysiology
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• v.5 no.2
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• pp.187-191
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• 2003

Purpose: MEPs elicited by transmagnetic stimulations of the motor cortex are facilitated by voluntary muscle contraction. We evaluated the effects of the imagination of the movements on latencies of MEPs and reciprocal inhibition by using transmagnetic stimulations. Methods: Twenty two healthy volunteers(eight men and fourteen women) were studied. TMSs were delivered at rest and during imagining abducting or adducting right thumb. A stimulator with a round coil and a fixed intensity of 80% of maximum was used to evoke MEPs. MEPs were evoked by magnetic stimulations over the scalp and cervical spine(C7-T1), and central motor conduction times(CMCT) were calculated by subtracting the latency of compound muscle action potentials(CMAPs) obtained by stimulating over the cervical spine from that obtained by stimulating over the scalp. The motor evoked potentials were recorded from right abductor pollicis brevis muscle(APB) and adductor pollicis muscle(AP) simultaneously. Results: Imagination of abduction resulted in a shortened latency of the CMAPs in APB, and a prolonged latency in AP. Imagination of adduction resulted in a shortened latency in AP, and a prolonged latency in APB. But the imagination caused no significant change in the latency of CMAPs elicited by stimulation over cervical spine. Therefore, the changes of the CMCTs account for these latency changes with imagination of movement. With the imagination of abduction, there are significant reduction of the CMCT's in APB(10.8%) and prolongation in AP(5.8%). On the other hand, with the imagination of adduction, prolongation of the CMCT's in APB(7.3%) and reduction in AP(5.9%) were observed. Conclusion: These findings indicate that imagination of muscle contraction increases the excitability of the human corticospinal system. Reciprocal inhibition may be accountable for the prolonged latency in the antagonist muscle.

• Journal of the Korean Chemical Society
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• v.37 no.4
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• pp.401-407
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• 1993

The titanium oxide thin films were prepared by air oxidation and water vapor oxidation. The electrochemical properties of the electrodes were studied in 1M NaOH solution. The peak potentials of oxygen reduction from cyclic voltammogram techniques were observed at aroung -0.9 ∼ -1.0 V vs. SCE and the reaction was totally irreversible process. The electrochemical properties of titanium dioxide electrodes prepared by water vapor oxidation exhibited different from the air oxidized electrodes, but it was similar to single crystal $TiO_2$. The peak potentials of oxygen reduction were observed at slightly more positive than flat band potentials and depended on pH.

• Journal of Electrochemical Science and Technology
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• v.4 no.4
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• pp.140-145
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• 2013

This study describes the electrodeposition of $Cu_2Se$ thin films with a two-step approach that is based on the initial modification of polycrystalline Au electrode with a selenium overlayer followed by a cathodic stripping of the layer as $Se^{2-}$ in a 1 M lactic acid electrolyte containing $Cu^{2+}$ ions. For this two-step approach to be effective, the $Cu^{2+}$ reduction potential should be shifted to more negative potentials passed potentials for the reduction of Se to $Se^{2-}$. This was accomplished by the complexation of $Cu^{2+}$ ions with lactic acid. The resultant $Cu_2Se$ films were characterized by linear sweep voltammetry combined with electrochemical quartz crystal microgravimetry, UV-vis absorption spectrometry and Raman spectroscopy. Photoelectrochemical experiments revealed that $Cu_2Se$ synthesized thus, behaved as a p-type semiconductor.

• Journal of the Korean Chemical Society
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• v.33 no.4
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• pp.399-405
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• 1989

The dependence of voltammetric parameters on the pressure for the reduction of Cu(II) in 0.5M KCl aqueous solution has been studied. In this system micro platinum electrode, standard calomel electrode and a helix type of platinum wire were used as the working, the reference and the auxilary electrode, respectively. With increasing the pressure from 1 to 1,800 bars, the half wave potentials of first reduction wave are shifted to the more negative potentials. And the diffusion currents of first and second reduction wave become considerably larger with increase in pressure from 1 to about 1,000 bars but are getting smaller beyond 1,000 bars. The good linear relationships between diffusion current and the concentrations of Cu(II) are established over all pressure range($1{\sim}1,800$ bars). The reversibility of the each reduction step is not changed with increasing pressure.