• Journal of Korean Physical Therapy Science
• /
• v.14 no.1_4
• /
• pp.11-23
• /
• 2007

This study was performed to evaluate the effects of low-intensity ultrasound application to the peripheral nerve injury animal model on enhancement of nerve regeneration and functional recovery. Using aseptic microsurgical techniques, the sciatic nerve of adult male Sprague-Dawley rats was crushed at the outside of right mid-thigh for 30 seconds with fine forceps. Beginning just after surgery, various continuous-wave ultrasound treatments with intensities of 0.2 W/$cm^2$, 0.5 W /$cm^2$ and 1.0 W /$cm^2$ operated at 1 MHz or sham treatment were applied to the opposite inside of the crush site for 1 minute every other day with a transducer moving speed of 2cm/sec. For evaluation of the progress of sciatic nerve regeneration, c-Fos expression in the lumbar spinal cord (L4-5) dorsal horn was investigated. c-fos expression was markedly increased at 1hour after sciatic nerve crush injury, then gradually decreased thereafter. The c-fos expressions were significantly decreased (p<0.05) in all the experimental groups in comparison with the control group until 3days post-crush, and the degrees of decrease were higher in 0.5 W/$cm^2$ and 1 W/$cm^2$ intensity ultrasound application groups. It is suggested that low-intensity ultrasound application to an animal model of sciatic crush injury may suppress pain transmission and promote nerve regeneration, and which may result in delayed progress of muscle atrophy and accelerated progress of muscle recovery and eventually may result in accelerated and improved foot function recovery.

• Proceedings of the SAREK Conference
• /
• 2008.06a
• /
• pp.288-293
• /
• 2008

The cooling load in winter is significant in many commercial buildings and hotels because of the usage of office equipments and the high efficiency of wall insulation. The development of a multi-heat pump that can cover heating and cooling simultaneously for each indoor unit is required. In this study, the performance of a multi-heat pump with 3-piping system was investigated as a function of refrigerant charge and its performance was analyzed in cooling mode, heating mode, and heat recovery mode. COP in the heating or cooling mode showed little dependence on refrigerant charge at overcharge conditions, while those were strongly dependent on refrigerant charge at undercharge conditions and outdoor inlet temperature. In the heat recovery mode, the performance of the system was very sensitive to charge amount at all conditions. Optimum charge amount in the heat recovery mode was 14% lower than that in the cooling mode at the standard condition because the refrigerant only passed the indoor units. It is required to store the excessive refrigerant charge in a storage tank to optimize the system performance at operating modes.

• Korean Journal of Applied Biomechanics
• /
• v.19 no.3
• /
• pp.567-580
• /
• 2009

The purpose of this study was to find out how the combined exercise program has an influence on the physical recovery of the patients suffering from work-related back problems. Research objects consist of 43 patients suffering from back problems due to workplace accidents. The result of the study shows that the combined exercise program increased muscular strength and endurance significantly and worked positively in lumbar recovery of the patients. It also increased the lowered flexibility caused by back pain to the level of normal state. In addition, the program was effective on the correction of the bad pose of body and scoliosis. Moreover, it helped improve on lifting, social life and reduce in the duration and the frequency of outbreak of pain. Finally, according to the result of this study, the combined exercise program was shown to be effective and appropriate for the patients suffering from work-related back problems.

• Journal of Microbiology and Biotechnology
• /
• v.21 no.9
• /
• pp.979-987
• /
• 2011

Culture pH change has some important roles in signal transduction and secondary metabolism. We have already reported that acidic pH shock enhanced actinorhodin production in Streptomyces coelicolor. Among many potential governing factors on pH variation, the putative $Na^+/H^+$ antiporter (sha) genes in S. coelicolor have been investigated in this study to elucidate the association of the sha on pH variation and secondary metabolism. Through the transcriptional analysis and overexpression experiments on 8 sha genes, we observed that most of the sha expressions were promoted by pH shock, and in the opposite way the pH changes and actinorhodin production were enhanced by the overexpression of each sha. We also confirmed that sha8 especially has a main role in maintaining cell viability and pH homeostasis through $Na^+$ extrusion, in salt effect experiment under the alkaline medium condition by deleting sha8. Moreover, this gene was observed to have a function of pH recovery after pH variation such as the pH shock, being able to cause the sporulation. However, actinorhodin production was not induced by the only pH recovery. The sha8 gene could confer on the host cell the ability to recover pH to the neutral level after pH variation like a pH drop. Sporulation was closely associated with this pH recovery caused by the action of sha8, whereas actinorhodin production was not due to such pH variation patterns alone.

• Journal of Dental Rehabilitation and Applied Science
• /
• v.29 no.4
• /
• pp.399-406
• /
• 2013

Reports about the intrusion of a natural tooth bounded by implants are very rare, although some concerns have been discussed on the intrusion of teeth connected to implants. A female aged 56 years received an implant (mandibular right first premolar) and post/core onto root rest (mandibular right second premolar) and was restored by single zirconia crown, respectively. Molars were implant restorations. Four month after loading, second premolar was intruded and prominent gap was shown between opposite tooth. Because nonspecific discomfort was expressed, observation was decided after explanation of prognosis of tooth without treatment. Three month later reversal to original position was detected on the periapical radiographs and fully recovered position with intimate contact was completed 11 more months later. Till now 2 years and 3 month observation is being performed. Through the observation of spontaneous recovery of a natural tooth bounded by implants, the cause of intrusion and a mechanism of spontaneous recovery could be estimated.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
• /
• 2001.05b
• /
• pp.8-11
• /
• 2001

In this study. the recovery of plasma induced damage in the etched PZT thin film with $O_2$ re-annealing have been investigated. The PZT thin films were etched as a function of $Cl_2/Ar$ and additive $CF_4$ into $Cl_{2}(80%)/Ar(20)%$. The etch rates of PZT thin films were $1600\dot{A}/min$ at $Cl_{2}(80%)/Ar(20)%$ gas mixing ratio and $1970\dot{A}/min$ at 30 % additive $CF_4$ into $Cl_{2}(80%)/Ar(20)%$. The etched profile of PZT films was obtained above 70 by SEM. In order to recovery properties of PZT thin films after etching, the etched PZT thin films were re-annealed at various temperatures in $O_2$ atmosphere. From the hysteresis curves, ferroelectrical properties are improved by $O_2$ re-annealing process. The improvement of ferroelectric behavior at annealed sample is consistent with the increase of the (100) and (200) PZT phase revealed by x-ray diffraction (XRD). From XPS analysis, intensity of Pb-O, Zr-O and Ti-O peak are increased and the chemical residue peak is reduced by $O_2$ re-annealing. The ferroelectric behavior consistent with the dielectric nature of TixOy is recovered by $O_2$ recombination during rapid thermal annealing process. From AFM images, it shows that the surface roughness of re-annealed sample after etching is improved.

• International Journal of Aeronautical and Space Sciences
• /
• v.13 no.1
• /
• pp.117-125
• /
• 2012

This paper presented the design of SRPS, ground function test, and the deployment test on a high speed taxi of KC-100 airplane. KAI has developed a spin recovery system in collaboration with Airborne Systems for KC-100 general aviation airplane. Spin mode analysis, rotary balance and forced oscillation tests were performed to obtain the rotational, dynamic derivatives in the preliminary design phase. Prior to the detailed design process of SRPS, approximations for initial estimation of design parameters- fineness ratio, parachute porosity, parachute canopy filling time, and deployment method- were considered. They were done based on the analytical disciplines such as aerodynamics, structures, and stability & control. SRPS consists of parachute, tractor rocket assembly for deployment, attach release mechanism (ARM) and cockpit control system. Before the installation of SRPS in KC-100 airplane, all the control functions of this system were demonstrated by using SBTB(System Breakout Test Box) in the laboratory. SBTB was used to confirm if it can detect faults, and simulate the firing of pyrotechnic devices that control the deployment and jettison of SRPS. Once confirmed normal operation of SRPS, deployment and jettison of parachute on the high speed taxiing were performed.

• Biomedical Science Letters
• /
• v.21 no.2
• /
• pp.92-102
• /
• 2015

This work aimed to study whether rice bran extract fermented with Lactobacillus plantarum (LW) promotes functional recovery and reduces cognitive impairment after ischemic brain injury. Ischemic brain injury was induced by middle cerebral artery occlusion (MCAO) in rats. Four groups were studied, namely the (1) sham, (2) vehicle, (3) donepezil, and (4) LW groups. Animals were injected with LW once a day for 7 days after middle cerebral artery occlusion. LW group showed significantly improved neurological function as compared to the vehicle group, as well as enhanced learning and memory in the Morris water maze. The LW group showed the greatest functional recovery. Moreover, the LW group showed an enhanced more survival cells anti-apoptotic effect in the cortex and neural cell densities in the hippocampal DG and CA1. In addition, this group showed enhanced expression of neurotrophic factors, antioxidant genes, and the acetylcholine receptor gene, as well as synaptophysin (SYP), Fox-3 (NeuN), doublecortin (DCX), and choline acetyltransferase (ChAT) proteins. Our findings indicate that LW treatment showed the largest effects in functional recovery and cognitive improvement after ischemic brain injury through stimulation of the acetylcholine receptor, antioxidant genes, neurotrophic factors, and expression of NeuN, SYP, DCX, and ChAT.

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.29 no.11B
• /
• pp.956-966
• /
• 2004

Nowadays, NGN(Next Generation Network) is evolving into network with packet based QoS.\ulcorner This paper presents the recovery method as a selecting way of more efficient path in MPLS network that reduces the service interruption time. In order to increase the efficiency of usage of recovering resource which is one of major functions of disorder recovering, it opens the state information of each Node both to fault detector and bandwidth broker so that it reduces message transmission time for recovery when functional disorder occurs. in addition, by effective management and adjustment of required bandwidth of entire network depending on the changes of traffic load, it improves the efficiency of bandwidth usage. and in MPLS network supporting priority selection function, it allocates domains depending on the traffic relating to priority order to the entire network so that\ulcorner it efficiently allocates proper resources to the restoring process between the entry and the end for the traffic of high priority and for low priority traffic, it restores path oかy inside disordered domain. by doing this, it reduces resetting time and unnecessary massage transmission.

• Annals of Clinical Neurophysiology
• /
• v.16 no.2
• /
• pp.62-69
• /
• 2014

Background: Neuromodulation therapy has been used to an adjunctive treatment promoting motor recovery in stroke patients. The objective of the study was to determine the effect of repetitive transcranial magnetic stimulation (rTMS) on neurobehavioral recovery and evoked potentials in rats with middle cerebral artery occlusion. Methods: Seventy Sprague-Daley rats were induced permanent middle cerebral artery occlusion (MCAO) stroke model and successful stroke rats (n=56) assigned to the rTMS (n=28) and sham (n=28) group. The 10 Hz, high frequency rTMS gave on ipsilesional forepaw motor cortex during 2 weeks in rTMS group. The somatosensory evoked potential (SSEP) and motor evoked potential (MEP) were used to evaluate the electrophysiological changes. Behavioral function of the stroke rat was evaluated by the Rota rod and Garcia test. Results: Forty rats ($N_{rTMS}=20;\;N_{sham}=20$) completed all experimental course. The rTMS group showed better performance than sham group in Rota rod test and Garcia test at day 11 (p<0.05) but not day 18 (p>0.05). The amplitude of MEP and SSEP in rTMS group was larger than sham group at day 18 (p<0.05). Conclusions: These data confirm that the high frequency rTMS on ipsilesional cerebral motor cortex can help the early recovery of motor performance in permanent middle cerebral artery stroke model and it may simultaneously associate with changes in neurophysiological activity in brain.