• 한국산학기술학회논문지
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• 제16권9호
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• pp.6254-6259
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• 2015

광시스템상에는 외부로부터의 잡음과 시스템 자체의 잡음이 항상 존재하는데, 이러한 잡음은 광시스템의 성능을 저하시키는 요인으로 작용하게 되어 결국에는 시스템의 에러확율을 변화시키게 된다. 이에 본 논문에서는 광시스템의 특성변수인 m 값을 도입하여 다양한 m값의 변화에 따라 광시스템의 에러확률을 ${\kappa}$-자승법을 이용하여 계산하였다. 계산 결과 m값에 따라 광시스템의 에러확률이 변화함을 확인하였고, 광시스템의 표준에럭확률인 $10^{-9}$을 유지하는 경우 m값을 400정도로 유지하면 됨을 확인하였다. 이는 m값이 큰 경우는 광시스템이 저출력임을 의미하므로 보다 작은 출력의 광원을 사용해도 광시스템의 에러확율을 유지하는데 문제가 없음을 알 수 있었다. 이는 일반적인 경우 저출력의 광원을 사용하는 경우 광시스템의 수신단에서 신호를 증폭하는 전치증폭기를 사용하지 않아도 됨을 의미하므로 보다 효율적이며 저렴하게 광시스템을 구현할 수 있음을 의미한다.

• 정보처리학회논문지C
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• 제9C권2호
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• pp.189-196
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• 2002

IPSec은 공용 네트워크 상에서 암호화와 인증, 무결성을 제공하기 위해 사용되는 프로토콜이다. IPSec에서는 전송되는 패킷에 암호화와 인증, 무결성을 추가해 전달하기 위해 ESP프로토콜을 사용한다. ESP는 패킷 암호화를 위해 DES-CBC 알고리즘을 이용하는데 이 모드에서는 ESP프로토콜로 보호되어 전송되는 데이터를 암호화하기 위한 초기 값으로 IV(Initialization Vector) 값을 사용한다. 이 값은 수신 측의 패킷 복호화를 위해 공개적으로 전달되므로 중간에 공격자에 의해 공격당할 위험이 많다. IV의 값이 조금이라도 변경되면 ESP의 모든 데이터의 복호화가 이루어지지 않고 상위 레벨의 정보가 변경되는 통 심각한 문제가 발생한다. 이것은 보안을 목적으로 하는 IPSec에서는 치명적인 약점이 된 수 있다. 따라서 본 논문에서는 ESP프로토콜에서의 문제점인 IV를 안전하게 전송하기 위한 새로운 알고리즘을 제시한다. 이 방법은 IV 값을 DES-ECB 알고리즘을 이용하여 암호화하여 IV 공격을 방어하고 메시지 인증 함수를 추가 적용하여 ESP 전체 데이터의 무결성 체크도 가능하게 한다. 제안된 알고리즘으로 IV와 데이터에 대한 공격을 방어할 수 있고 안전한 전송을 보장한다.

• 한국정보과학회논문지:정보통신
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• 제29권2호
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• pp.156-164
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• 2002

IPSec은 공용 네트워크 상에서 암호화와 인증, 무결성을 제공하기 위해 사용되는 프로토콜이다. IPSec에서는 전송되는 패킷에 암호화와 인증, 무결성을 추가해 전달하기 위해 ESP 프로토콜을 사용한다. ESP는 패킷 암호화를 위해 DES-CBC 알고리즘을 이용하는데 이 모드에서는 ESP 데이타를 암호화하기 위한 초기 값으로 IV(Initialization Vector)가 사용된다. 이 값은 수신 측의 패킷 복호화를 위해 공개적으로 전달되므로 중간에 공격자에 의해 공격당할 위험이 많다. IV의 값이 조금이라도 변경되면 ESP 의 모든 데이타의 복호화가 이루어지지 않고 상위 레벨의 정보가 변경되는 등 심각한 문제가 발생한다. 이것은 보안을 목적으로 하는 IPSec에서는 치명적인 약점이 될 수 있다. 따라서 본 논문에서는 IV를 안전하게 전송하기 위한 새로운 알고리즘을 제시한다. 이 방법은 DES-ECB 알고리즘을 이용하여 IV 값을 암호화하여 IV 공격을 방어하고 메시지 인증 함수를 추가 적용하여 ESP 전체 데이타의 무결성 체크도 가능하게 한다. 제안된 알고리즘으로 IV와 데이타에 대한 공격을 방어하고 안전한 전송을 보장한다.

• Genomics & Informatics
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• 제16권4호
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• pp.26.1-26.12
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• 2018

Shigella spp. constitutes some of the key pathogens responsible for the global burden of diarrhoeal disease. With over 164 million reported cases per annum, shigellosis accounts for 1.1 million deaths each year. Majority of these cases occur among the children of the developing nations and the emergence of multi-drug resistance Shigella strains in clinical isolates demands the development of better/new drugs against this pathogen. The genome of Shigella flexneri was extensively analyzed and found 4,362 proteins among which the functions of 674 proteins, termed as hypothetical proteins (HPs) had not been previously elucidated. Amino acid sequences of all these 674 HPs were studied and the functions of a total of 39 HPs have been assigned with high level of confidence. Here we have utilized a combination of the latest versions of databases to assign the precise function of HPs for which no experimental information is available. These HPs were found to belong to various classes of proteins such as enzymes, binding proteins, signal transducers, lipoprotein, transporters, virulence and other proteins. Evaluation of the performance of the various computational tools conducted using receiver operating characteristic curve analysis and a resoundingly high average accuracy of 93.6% were obtained. Our comprehensive analysis will help to gain greater understanding for the development of many novel potential therapeutic interventions to defeat Shigella infection.

• Journal of Gastric Cancer
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• 제19권3호
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• pp.315-328
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• 2019

Purpose: To investigate the clinical value of serum miR-221-3p and miR-122-5p expression levels in the diagnosis and prognosis of gastric cancer. Materials and Methods: Serum samples from 141 gastric cancer cases (gastric cancer group), 110 gastric polyps (gastric polyp group), and 75 healthy people (healthy control) were used to detect miR-221-3p and miR-122-5p expression using real-time reverse transcription polymerase chain reaction. Results: Serum miR-221-3p expression was significantly higher in the gastric cancer group than in the gastric polyp group, and it was significantly lower than that before operation. The miR-221-3p expression was significantly higher in the death group than in the survival group. The proliferation and migration ability significantly increased and the apoptosis rate significantly decreased by miR-221-3p transfection in gastric cancer cells. In contrast, the function of miR-122-5p in gastric cancer cells was opposite of miR-221-3p. Serum miR-221-3p expression was negatively correlated with that of miR-122-5p in gastric cancer. Serum miR-221-3p and miR-122-5p expressions were significantly correlated with the degree of differentiation, tumor, node, metastasis stage, lymph node metastasis, and invasion depth. miR-221-3p and miR-122-5p expression levels were independent prognostic factors for postoperative gastric cancer. In the diagnosis and predicting prognosis of gastric cancer, receiver operating characteristic analysis revealed that the area under curve of combined detection of serum miR-221-3p and miR-122-5p expression had a greater diagnostic effect than either single maker. Conclusions: The miR-221-3p and miR-122-5p are involved in the development of gastric cancer, and they have important clinical values in gastric cancer diagnosis and prognosis.

• Clinical and Experimental Pediatrics
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• 제62권8호
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• pp.307-311
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• 2019

Purpose: Necrotizing enterocolitis (NEC) is one of the most serious complications of prematurity. Many risk factors can contribute to the development of NEC. The epidermal growth factor (EGF) plays a major role in intestinal barrier function, increases intestinal enzyme activity, and improves nutrient transport. The aim of this study was to assess the role of epidermal growth factor in the development of NEC in preterm neonates. Methods: In this study, 130 preterm neonates were included and divided into 3 groups, as follows: group 1, 40 preterm neonates with NEC; group 2, 50 preterm neonates with sepsis; and group 3, 40 healthy preterm neonates as controls. The NEC group was then subdivided into medical and surgical NEC subgroups. The serum EGF level was measured using enzyme-linked immunosorbent assay. Results: Serum EGF levels (pg/dL) were significantly lower in the NEC group (median [interquartile range, IQR], 9.6 [2-14]) than in the sepsis (10.1 [8-14]) and control groups (11.2 [8-14], P<0.001), with no significant difference between the sepsis and control groups, and were positively correlated with gestational age (r=0.7, P<0.001). A binary logistic regression test revealed that low EGF levels and gestational ages could significantly predict the development of NEC. The receiver-operating characteristic curve for EGF showed an optimal cutoff value of 8 pg/mL, with 73.3% sensitivity, 98% specificity, and an area under the curve of 0.92. Conclusion: The patients with NEC in this study had significantly lower serum EGF levels (P<0.001), which indicated that EGF could be a reliable marker of NEC in preterm neonates.

• Imaging Science in Dentistry
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• 제49권2호
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• pp.139-151
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• 2019

Purpose: This study was performed to investigate the effect of exposure parameters on image quality obtained using a cone-beam computed tomography (CBCT) scanner and the relationship between physical factors and clinical image quality depending on the diagnostic task. Materials and Methods: CBCT images of a SedentexCT IQ phantom and a real skull phantom were obtained under different combinations of tube voltage and tube current (Alphard 3030 CBCT scanner, 78-90 kVp and 2-8 mA). The images obtained using a SedentexCT IQ phantom were analyzed technically, and the physical factors of image noise, contrast resolution, spatial resolution, and metal artifacts were measured. The images obtained using a real skull phantom were evaluated for each diagnostic task by 6 oral and maxillofacial radiologists, and each setting was classified as acceptable or unacceptable based on those evaluations. A statistical analysis of the relationships of exposure parameters and physical factors with observer scores was conducted. Results: For periapical diagnosis and implant planning, the tube current of the acceptable images was significantly higher than that of the unacceptable images. Image noise, the contrast-to-noise ratio (CNR), the line pair chart on the Z axis, and modulation transfer function (MTF) values showed statistically significant differences between the acceptable and unacceptable image groups. The cut-off values obtained using receiver operating characteristic curves for CNR and MTF 10 were useful for determining acceptability. Conclusion: Tube current had a major influence on clinical image quality. CNR and MTF 10 were useful physical factors that showed significantly associations with clinical image quality.

• 한국멀티미디어학회논문지
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• 제24권6호
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• pp.768-788
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• 2021

The reversible data hiding technique safely transmits secret data to the recipient from malicious attacks by third parties. In addition, this technique can completely restore the image used as a transmission medium for secret data. The reversible data hiding schemes have been proposed in various forms, and recently, the reversible data hiding schemes based on interpolation are actively researching. The reversible data hiding scheme based on the interpolation method expands the original image into the cover image and embed secret data. However, the existing interpolation-based reversible data hiding schemes did not embed secret data during the interpolation process. To improve this problem, this paper proposes embedding the first secret data during the image interpolation process and embedding the second secret data into the interpolated cover image. In the embedding process, the original image is divided into blocks without duplicates, and the maximum and minimum values are determined within each block. Three way searching based on the maximum value and two way searching based on the minimum value are performed. And, image interpolation is performed while embedding the first secret data using the PVD scheme. A stego image is created by embedding the second secret data using the maximum difference value and log function in the interpolated cover image. As a result, the proposed scheme embeds secret data twice. In particular, it is possible to embed secret data even during the interpolation process of an image that did not previously embed secret data. Experimental results show that the proposed scheme can transmit more secret data to the receiver while maintaining the image quality similar to other interpolation-based reversible data hiding schemes.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제16권1호
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• pp.188-210
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• 2022

As a promising technique to support tremendous numbers of Internet of Things devices and a variety of applications efficiently, mobile edge computing (MEC) has attracted extensive studies recently. In this paper, we consider a MEC-assisted peer-to-peer (P2P) mobile communication system where MEC servers are deployed at access points to accelerate the communication process between mobile terminals. To capture the tradeoff between the time delay and the energy consumption of the system, a cost function is introduced to facilitate the optimization of the computation and communication resources. The formulated optimization problem is non-convex and is tackled by an iterative block coordinate descent algorithm that decouples the original optimization problem into two subproblems and alternately optimizes the computation and communication resources. Moreover, the MEC-assisted P2P communication system is compared with the conventional P2P communication system, then a condition is provided in closed-form expression when the MEC-assisted P2P communication system performs better. Simulation results show that the advantage of this system is enhanced when the computing capability of the receiver increases whereas it is reduced when the computing capability of the transmitter increases. In addition, the performance of this system is significantly improved when the signal-to-noise ratio of hop-1 exceeds that of hop-2.

• Geomechanics and Engineering
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• 제34권3호
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• pp.267-284
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• 2023

Landslides are one of the most dangerous phenomena and natural disasters. Landslides cause many human and financial losses in most parts of the world, especially in mountainous areas. Due to the climatic conditions and topography, people in the northern and western regions of Iran live with the risk of landslides. One of the measures that can effectively reduce the possible risks of landslides and their crisis management is to identify potential areas prone to landslides through multi-criteria modeling approach. This research aims to model landslide potential area in the Oshvand watershed using a support vector machine algorithm. For this purpose, evidence maps of seven effective factors in the occurrence of landslides namely slope, slope direction, height, distance from the fault, the density of waterways, rainfall, and geology, were prepared. The maps were generated and weighted using the continuous fuzzification method and logistic functions, resulting values in zero and one range as weights. The weighted maps were then combined using the support vector machine algorithm. For the training and testing of the machine, 81 slippery ground points and 81 non-sliding points were used. Modeling procedure was done using four linear, polynomial, Gaussian, and sigmoid kernels. The efficiency of each model was compared using the area under the receiver operating characteristic curve; the root means square error, and the correlation coefficient . Finally, the landslide potential model that was obtained using Gaussian's kernel was selected as the best one for susceptibility of landslides in the Oshvand watershed.