• Toxicological Research
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• v.13 no.4
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• pp.359-365
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• 1997

Many factors are known to be responsible for cerebral ischemic injury, such as excitatory neurotransmitters, increased intraneuronal calcium, or disturbance of cellular energy metabolism. Recently, oxygen free radicals, formed during ischemia/reperfusion, have been proposed as one of the main causes of ischemia/reperfusion injury. Therefore, to investigate the role of oxygen free radical during ischemia/reperfusion, in the present study the effect of endogenous oxygen free radical scavenger, superoxide dismutase / catalase(SOD / catalase) on the release of [$^3$H]-5-hydroxytryptamine([$^3$H]-5-HT) during hypoxia/reoxygenation in rat hippocampal slices was measured. The hippocampus was obtained from the rat brain and sliced 400 gm thickness with manual chopper. After 30 min's preincubation in the normal buffer, the slices were incubated for 20 min in a buffer containing [$^3$H]-5-HT(0.1 $\mu$M, 74 $\mu$Ci) for uptake, and washed. To measure the release of [$^3$H]-5-HT into the buffer, the incubation medium was drained off and refilled every ten minutes through a sequence of 14 tubes. Induction of hypoxia for 20 min (gassing it with 95% N$_2$/5% CO$_2$) was done in the 6th and 7th tube, and oxygen free radical scavenger, SOD / catalase was added 10 minutes prior to induction of hypoxia. The radioactivity in each buffer and the tissue were counted using liquid scintillation counter and the results were expressed as a percentage of the total activity. When slices were exposed to hypoxia for 20 min, [$^3$H]-5-HT release was markedly decreased and a rebound release of [$^3$H]-5-HT was observed on the post-hypoxic reoxygenation period. SOD / catalase did not changed the release of [$^3$H]-5-HT in control group, but inhibited the decrease of [$^3$H]-5-HT release in hypoxic period and rebound increase of [$^3$H]-5-HT in reoxygenation period. This result suggest that superoxide anion may play a role in the hypoxic-, and reoxygenation-induced change of [$^3$H]-5-HT release in rat hippocampal slices.

• Elastomers and Composites
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• v.34 no.1
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• pp.11-19
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• 1999

Rebound, storage and loss modulus, and tan ${\delta}$ were investigated on cured rubbers with various ratios of sulfur to accelerator and the volume fraction of carbon black in the cured rubbers. The rebound was increased as the sulfur to accelerator ratio and the volume fraction of carbon black decreased. The storage modulus decreased as the loading of carbon black and the strain increased regardless of the cure systems. The network structure formed by filler-filler interaction was destroyed above 6% strain regardless of the loading of carbon black, because constant storage modulus was shown at the higher strain than 3% for $40{\sim}50phr$ loading of carbon black and at the higher strain than 6% for 60 phr and above loading of carbon black. Little effect on loss modulus was found at the low loading of carbon black, but the peak of loss modulus was shown at 1% strain as the loading of carbon black was increased. Tan ${\delta}$ increased as the loading of carbon black and the strain were increased regardless of the cure system, and maximum tan ${\delta}$ was shown at 2% strain regardless of the loading of carbon black.

• Journal of the Korea Concrete Institute
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• v.16 no.3 s.81
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• pp.327-334
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• 2004

In this paper, method for the determination of removal time of the side forms in high strength concrete are discussed using the estimation model of compressive strength development, the development of bond strength and rebound number of P type Schmidt hammer in order to review the validity of existing regulation as to side form removal and offer effective quality control method. According to the results, as W/B increases by $10\%$, the setting time is shortened by about 2 hours. In the scope of the paper, required time to gain 8MPa of compressive strength is determined about 17 ${\~}$20 hours of age and $21{\~}25^{\circ}D{\cdot}D$ of maturity. Bond strength between form and concrete shows the highest value around final setting time, but decreases drastically after that. Amount of concrete sticking on the form is large before setting completed, but after that, its amount shows decline tendency. The rebound value test with P type schmidt hammer can be started faster by 2${\~}$3 hours than compressive strength test. It is also confirmed that the removal of forms is possible when the rebound value of P type schmidt hammer is more than 32. It is found from the results that existing regulation regarding removal time of the side form of high strength concrete provided in KCI needs no revision because required time to gain the strength provided in KCI has no adverse effect on strength development at early age and surface condition during stripping the side form. Effective procedure to decide the removal time of side form can be performed by applying P type Schmidt hammer.

• Journal of the Korea institute for structural maintenance and inspection
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• v.26 no.6
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• pp.148-156
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• 2022

Although most domestic concrete structures are simultaneously exposed to freeze-thaw and chloride environments, concrete durability in the field is evaluated by each single action, and the evaluation of chloride-caused damage of concrete requires additional indoor experimental analysis of chloride contents by coring samples from structures in the field. However, in Korea, policies to strengthen facility maintenance, such as 「Special Act on the Safety Control and Maintenance of Establishments」 and 「Framework Act on Sustainable Infrastructure Management」, have been established and implemented since 2018 and facilities subject to safety inspection management by the government and local governments increases, the effective simplification technology for the inspection and diagnosis of concrete structure is needed. Therefore, this study attempted to evaluate the possibility of determining the acceleration chloride penetration of freeze-thaw damaged concrete by using the surface rebound value. For this purpose, concrete specimens already having freeze-thaw damage by exposure to the freeze-thaw acceleration environment were immersed in chloride water. After that, the acceleration relationship of chloride penetration according to freeze-thaw damage was analyzed using the amount of chloride contents in concrete.

• Journal of the Korean Recycled Construction Resources Institute
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• v.5 no.1
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• pp.59-67
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• 2017

The objective of this paper is to investigate experimentally the effect of replacement of recycled coarse aggregates with 5~13mm in size on a field applicability of concretes through Mock-up test. Seven different mock-up specimens were prepared with the size of $1200{\times}800{\times}800mm$ simulating column and wall. For the concrete mixtures, 24MPa, 27MPa and 40MPa of nominal strength were adopted with 30% and 70%(only for 24MPa) of 5~13mm recycled coarse aggregate (RCA) replacement and without 5~13mm RCA(Plain). For test items, slump, slump flow, compressive strength with different curing conditions, core drilling, rebound numbers and drying shrinkage were measured. Test results indicated that 30% of 5~13 mm RCA replacement resulted in increase in slump, slump flow and resistance against segregation, while air contents decreased compared to those of plain mixture. Compressive strength of concrete with 30% of 5~13mm RCA was shown to be higher than that of plain mixture due to optimum packing effect associated with presence of well graded aggregates. Rebound number of the mock-up specimen with 30% of 5~13mm RCA had lower fluctuation according to hitting location than that of plain mock-up specimen. It is believed from the results of the study that replacement of 30% of 5~13mm RCA brings desirable improvement in various aspect of concrete performance due to associated dense packing effect.

• Sleep Medicine and Psychophysiology
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• v.13 no.1
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• pp.5-10
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• 2006

Alcohol has extensive effects on sleep and daytime sleepiness. Alcohol has a sleep inducing effect and the effect of increased non-REM sleep and suppressed REM sleep during the first half portion of night sleep, but alcohol induces the effect of decreased non-REM sleep and increased light sleep and frequent awakenings and REM rebound during the second half portion of night sleep. Alcohol provokes chronobiological change such as the changes of amplitude or the phase shifts of hormones or core body temperature. The sleep disruption resulting from alcohol drinking may lead to daytime fatigue and sleepiness. The elderly are at particular in the increased risk of alcohol-related sleep disorders because they achieve higher levels of alcohol in the blood and brain than do younger adults after consuming an equivalent dose. Bedtime alcohol consumption among older adults may lead to unsteadiness if walking is attempted during the night, with increased risk of falls and injuries. Continued alcohol use for sleep induction often induces aggravation of insomnia, alcoholism or sleep related breathing disorders such as obstructive sleep apnea. Alcohol should not be used as substitution of sleep pill because of the dependence and tolerance for sleep inducing effect, and the sleep disruption produced by alcohol withdrawal.

• The Journal of Korea Assosiation for Disability and Oral Health
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• v.2 no.2
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• pp.142-146
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• 2006

Oral administration of chloral hydrate with hydroxyzine, nitrous oxide inhalation and intramuscular or intranasal administration of midazolam is the most commonly used pharmacological behavior management methods for the children in pre-cooperative stage or show negative behavior in pediatric dentistry. For oral administration of chloral hydrate with hydroxyzine, it is hard to apply to the patient refused to intake and with overweighted or elderly children and the effect of the drug decrease. Nitrous oxide and midazolam is anxiolytic agents and have limitation for properly managing the behavior of the children refuse to dental treatment. These occasions, deep sedation or general anesthesia can be considered. Although intravenous sedation with midazolam has many advantages such as, rapid onset and recovery, possible to titration and few side effect, no rebound effect by metabolites, the reports for, intravenous sedation with midazolam is insufficient in pediatric dentistry. We report the case in pre-cooperative stage. He is treated successfully under intravenous sedation with midazolam.

• Transactions of the Korean Society of Automotive Engineers
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• v.6 no.3
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• pp.97-105
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• 1998

High pressure injection is recently used to reduce the emissions and increase the power of DI diesel engine. This high pressure injection makes the spray strike the cylinder wall. This spray/wall impingement is known to affect the emission and performance of DI diesel engine such that it is very important to know the spray/wall impingement process. In this study, multidimensional computer program KIVA-II was used to clarify the effect of spray wall impingement by different injection spray angle with the spray/wall impingement model consiedering rebound and slide motion and also the improved submodel for liquid breakup, drop distortion model.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.22 no.1
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• pp.33-39
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• 2010

The film boiling heat transfer was experimentally investigated for the water sprays impacting on an inclined hot surface. Full cone spray nozzles were employed for the spray cooling experiment, and experiments were made for different inclination angles of $\theta=0^{\circ}$, $15^{\circ}$, $30^{\circ}$ and $45^{\circ}$. The experimental results show that, in the downstream region of the inclined hot surface, increasing the inclination angle increases the local heat flux slowly because of increasing the number of rebound droplets. However, the inclination angle of heat transfer surface had no remarkable effect on the local heat flux of spray cooling under the present test conditions.

• The Journal of Korean Medicine
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• v.21 no.4
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• pp.271-275
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• 2000

A growing number of people are concerned about their sleep. There are many people with chronic sleep disorders. As there are various causes in a disease, proper treatment according to each cause is necessary for a more effective treatment. In general, insomnia is classified into five categories of physical, physiological, psychological, psychiatric and pharmacological aspects. Sedative-hypnotics including benzodiazepine and non-benzodiazepine have widely been used in chronic insomniacs. However, most hypnotics including non-benzodiazepine cause some of dependence, tolerance, impaired daytime function and rebound insomnia. Therefore, we are looking forward to proposing an effective oriental treatment for insomnia. A 71-year-old male who had suffered from cerebral infarction was admitted to our department for oriental treatment of stroke and insomnia. Initial treatment modalities with administration of paroxetine were not effective. However administration of oriental medicine' Gochimmuwoo-san(Gaozhenwuyou-san)' achieved a desirable effect.