• 말소리와 음성과학
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• 제4권4호
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• pp.19-27
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• 2012

When two speakers read a text together, the produced speech has been shown to reduce a high degree of variability (e.g., pause duration and placement, and speech rate). This paper provides a quantitative analysis of speech rate variation exhibited in synchronous speech by examining the global and local patterns in two dialects of Mandarin Chinese (Taiwan and Shanghai). We analyzed the speech data in terms of mean speech rate and the reference of "Just Noticeable difference (JND)" within a subject and across subjects. Our findings show that speakers show lower and less variable speech rates when they read a text synchronously than when they read alone. This global pattern is observed consistently across speakers and dialects maintaining the unique local variation patterns of speech rate for each dialect. We conclude that paired speakers lower their speech rates and decrease the variability in order to ensure the synchrony of their speech.

• 말소리와 음성과학
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• 제5권4호
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• pp.91-98
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• 2013

This study investigates the difference in the evaluation of foreign-accentedness of English pronunciation across subject groups, evaluated accents, and compared components. This study independently evaluates the prosody and segmentals of the foreign-accented English sentences by pairwise difference rating. Using the prosody swapping technique, segmentals and prosody of the English sentences read by native speakers of American English (one male and one female) were combined with the corresponding segmentals and prosody of the English sentences read by male and female native speakers of Chinese, Japanese or Korean (one male and one female from each native language). These stimuli were evaluated by 4 different subject groups: native speakers of American English, Korean, Chinese, and Japanese. The results showed that the Japanese subject group scored higher in prosody difference than in segmental difference while the other groups scored the other way around. This study is significant in that the attitude toward the difference in segmentals and prosody of the foreign accents of English varies with the native language of the subject group. In other words, for native speakers of some languages, the difference in prosody could have a greater influence on the foreign-accentedness than the difference in segmentals, while for native speakers of other languages the other way around.

• Toxicological Research
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• 제33권3호
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• pp.173-182
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• 2017

In silico methods to predict toxicity include the use of (Quantitative) Structure-Activity Relationships ((Q)SARs) as well as grouping (category formation) allowing for read-across. A challenging area for in silico modelling is the prediction of chronic toxicity and the No Observed (Adverse) Effect Level (NO(A)EL) in particular. A proposed solution to the prediction of chronic toxicity is to consider organ level effects, as opposed to modelling the NO(A)EL itself. This review has focussed on the use of structural alerts to identify potential liver toxicants. In silico profilers, or groups of structural alerts, have been developed based on mechanisms of action and informed by current knowledge of Adverse Outcome Pathways. These profilers are robust and can be coded computationally to allow for prediction. However, they do not cover all mechanisms or modes of liver toxicity and recommendations for the improvement of these approaches are given.

• Genomics & Informatics
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• 제17권4호
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• pp.40.1-40.9
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• 2019

While studies aimed at detecting and analyzing indels or single nucleotide polymorphisms within human genomic sequences have been actively conducted, studies on detecting long insertions/deletions are not easy to orchestrate. For the last 10 years, the availability of long read data of human genomes from PacBio or Nanopore platforms has increased, which makes it easier to detect long insertions/deletions. However, because long read data have a critical disadvantage due to their relatively high cost, many next generation sequencing data are produced mainly by short read sequencing machines. Here, we constructed programs to detect so-called unmapped regions (UMRs, where no reads are mapped on the reference genome), scanned 40 Korean genomes to select UMR long deletion candidates, and compared the candidates with the long deletion break points within the genomes available from the 1000 Genomes Project (1KGP). An average of about 36,000 UMRs were found in the 40 Korean genomes tested, 284 UMRs were common across the 40 genomes, and a total of 37,943 UMRs were found. Compared with the 74,045 break points provided by the 1KGP, 30,698 UMRs overlapped. As the number of compared samples increased from 1 to 40, the number of UMRs that overlapped with the break points also increased. This eventually reached a peak of 80.9% of the total UMRs found in this study. As the total number of overlapped UMRs could probably grow to encompass 74,045 break points with the inclusion of more Korean genomes, this approach could be practically useful for studies on long deletions utilizing short read data.

• 말소리와 음성과학
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• 제4권2호
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• pp.121-126
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• 2012

This study deals with how stuttering changes in its frequency in a situation where adult participants who stutter are exposed to one type of background noise, that is, multi-talker babble noise. Eight American English-speaking adults who stutter participated in this study. Each of the subjects read aloud sentences under each of three speaking conditions (i.e., typical solo reading (TSR), typical choral reading (TCR), and multi-talker babble noise reading (BNR)). Speech fluency was computed based on a percentage of syllables stuttered (%SS) and speaking rate was also assessed to examine if there was significant change in rates as a measure of vocal change under each of the speaking conditions. The study found that participants read more fluently both during BNR and during TCR than during TSR. The study also found that participants did not show significant changes in speaking rate across the three speaking conditions. Some discussion was provided in relation to the effect of multi-talker babble noise on the frequency of stuttering and its further speculation.

• 말소리와 음성과학
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• 제1권1호
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• pp.77-86
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• 2009

This study observes how the combined intervention program effects on the acquisition reading pronunciation of Korean phonological process words and the acquisition aspects of each phonological process rules to four Korean learners whose first language is Chinese. The training program is the combination of multisensory Auditory, Visual and Kinethetic (AVK) approach, wholistic approach, and metalinguistic approach. The training purpose is to evaluate how accurately they read the words of the phonological process which have fortisization, nasalization, lateralization, intermediate sound /ㅅ/ (/${\int}iot"$/). We access how they read the untrained words which include the four factors above. The intervention effects are analyzed by the multiple probe across subjects design. The results indicate that the combined phonological process rule explanation and the words activity intervention affects the four Chinese subjects in every type of word. The implications of the study are these: First, it suggests the effect of Korean pronunciation intervention in a concrete way. Second, it offers how to evaluate the phonological process and how to train people who are learning Korean language.

• 한국환경보건학회지
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• 제39권2호
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• pp.130-137
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• 2013

Objectives: The OECD QSAR Application Toolbox was developed by the Organisation for Economic Cooperation and Development (OECD) to facilitate the practical use of QSAR approaches in regulatory contexts as well as to reduce the need for additional animal testing. In this study, human health and the ecotoxicity of chemicals were predicted by applying the OECD QSAR Application Toolbox and the results were compared with experimental data in order to evaluate the applicability of this program. Methods: Read-across, trend analysis, and QSAR of OECD QSAR Application Toolbox were used for the prediction of toxicity. Results: The toxicity prediction was conducted on 6,354 chemicals for which toxicity data have been produced on the six endpoints of skin sensitization, skin irritation, eye irritation, mutagenicity, and acute toxicities of fish and Daphnia. From the total of 6,354, we obtained prediction results for 1,621 chemicals (25.5%). Conclusions: The predicted properties of mutagenicity, skin sensitization, and acute aquatic toxicities were reasonably good when compared with experimental data, but other endpoints were not due to the limitation of applicable chemical groups.

• 한국정보과학회:학술대회논문집
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• 한국정보과학회 2006년도 한국컴퓨터종합학술대회 논문집 Vol.33 No.1 (A)
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• pp.250-252
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• 2006

Web technologies are gaining increased importance in automation and control systems. However, the choice of Web technologies depends on the use cases in the application environment. In industrial systems, the data can be got not only from many different field systems and devices but also from different OPC (OLE for Process Control) Servers. Current OPC Client might be able to read simple data from OPC Server, but there are some problems to get structured data and to exchange structured information between collaborating applications. Therefore, OPC Foundation has defined interfaces to OPC XML-DA (OPC XML Data Access) and OPC Complex Data that aim to solve those problems. The OPC XML-DA can facilitate the exchange of plant data across the internet, and upwards into the enterprise domain. In addition, the OPC Complex Data will extend the OPC DA specification to allow the OPC Client to read and decode any type of data from measurement and control systems on the plant floor. This paper will describe the concept of OPC XML-DA and OPC Complex Data. And then it proposes a mechanism to implement the OPC Complex Data into OPC XML-DA Server. Additionally, the paper also discusses the security aspects.

• 말소리와 음성과학
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• 제6권2호
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• pp.163-174
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• 2014

Korean L2 speakers have many problems learning the pronunciation of English words. One of these problems is vowel epenthesis. Vowel epenthesis is the insertion of vowels into or between words, and Korean learners of English typically do this between successive consonants, either within clusters, or across syllables, word boundaries or following final coda consonants. The aim of this study was to investigate whether individual differences in vowel epenthesis are more closely related to the perception and production of segments (vowels and consonants) and prosody or if they are relatively independent from these processes. Subjects completed a battery of production and perception tasks. They read sentences, identified vowels and consonants, read target words likely to have epenthetic vowels (e.g., abduction) and demonstrated stress recognition and epenthetic vowel perception. The results revealed that Korean second-language learners (L2) have problems with vowel epenthesis in production and perception, but production and perception abilities were not correlated with one another. Vowel epenthesis was strongly related to vowel production and perception, suggesting that problems with segments may be combined with L1 phonotactics to produce epenthesis.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2005년도 추계종합학술대회
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• pp.763-767
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• 2005

RAID는 디스크 배열 상에 데이터를 이중으로 저장하거나 패리티를 같이 사용하는 기법으로 디스크에 장애가 일어났을 경우 이를 복구하는 구조로 되어 있다. RAID5는 읽기와 큰 데이터 쓰기 접근을 수행하는 2차 저장 장치에서 높은 신뢰성과 비용 효과를 갖는다. 그러나 RAID5는 작은 크기의 데이터 쓰기에 대하여 패리티를 다시 계산하고 유지하는데 소비되는 오버헤드 때문에 성능이 저하된다. 본 논문에서는 패리티 로깅 기법에 의한 파일, 스트라이핑 크기에 대한 RAID5의 읽기/쓰기 성능을 비교 시스템의 성능을 개선한다.