• 터널과지하공간
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• 제19권2호
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• pp.86-94
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• 2009

암석파괴역학과 파괴인성(rock fracture toughness) 이하의 응력확대계수(stress intensity factor)에서 균열이 성장하는 현상을 이용하여 암석 절리면의 비선형 강도특성과, 시간의 경과에 따라 파괴가 진행되는 특성을 고려한 수치해석용 3차원 절리면 요소를 개발하였다. 이 절리면 요소를 사용하여 암석 절리면 전단시험을 수치해석으로 모사한 결과, 전단응력이 증가하고 시간이 경과함에 따라 절리면 사이에 연결된 절리면 내 접점(asperity in joint)에서 암석의 파괴인성보다 응력확대계수가 작음에도 불구하고 균열이 발생하였고 시간이 경과하면서 균열이 성장, 절리면 내 접점이 파괴되었다. 이와 같이 각각의 절리면 내 접점의 파괴에 따라 절리면의 강도는 감소하고, 절리면의 전단응력은 응력경화와 응력연화 후 잔류응력에 도달하는 비선형거동을 보이면서 시간의 경과에 따라 점진적으로 파괴되었다.

• 대한수의학회지
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• 제24권2호
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• pp.137-147
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• 1984

가토 자궁 근충에서 분리한 상피세포를 10% 송아지혈청, 3mM glutamine이 함유한 Basal Eagle 배지에서 배양한 결과 세포 성장 시간은 53시간이 소요되었고, estrogen에 insulin을 첨가했을 때는 40시간으로 감소하였다. Creatine kinase 활성 단위는 단백질 mg당 0.019 unit이었다. 활성의 30%가 이온상태가 높은 완충액에서 추출되었고, plasminogen 활성 인자는 세포 백만당 140 CTA unit였다.

• 자원환경지질
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• 제32권1호
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• pp.53-62
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• 1999

The possibility of heavy metal pollution by contaminated roadside soils was studied under controlled conditions. The soil samples from roadside and those from a retention pond consisting of settling particles were characterized by the XRD analyses and the sequential extraction experiments. Characterization by sequential extraction, for roadside soil indicates elevate total concentrations of heavy metals. The leaching behavior of the samples under different pH and time conditions were also studied. Differences between both types of samples result mainly from the buffering effect of carbonates, present in roadside soils and lacking from settling particles. Acid leaching of the settling particles is equivalent to the sum of FI+FII+FIII, while the amounts leached from roadside soil are lower probably from kinetic reasons. The buffering effects of carbonates were found to greatly delay the onset of the leaching reactions and the extent of dissolution in most metals except for Ca and Mn. The study of leaching kinetics at pH of 6.5 and 5 showed that Cd and Zn reached the maximum possible concentration within 3 days, while Pb did not show any sign of dissolution at both ph values. The absolute amounts of dissolved Cd and Zn increased by 7 to 9 times by decreasing the pH from 6.5 to 5, indicating slightly acidified rain may result in significant metal dissolution. As deduced from both sequential extraction and leaching experiments, the relative mobility of heavy metals is found to be : Mn=Cd>Zn>>Pb>Fe, in spite of large differences in heavy metal contents and localizations.

• 한국측량학회지
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• 제30권6_2호
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• pp.673-680
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• 2012

Long-term GPS data analysis was performed in order to analyze the seasonal variation of tropospheric delay and the success rate of the ambiguity resolution. For this analysis, a total of 57 stations including 10 IGS stations in East Asia were processed together with double-differenced observables using Bernese GPS Software V5.0. The time span for this study ranges from 2002.0 to 2012.5 (10.5 years). The average baseline length is 339.0 km and the maximum reaches up to 2,000 km. The analysis is focused on two things: the annual variation of the tropospheric delay and the ambiguity resolution rate. The tropospheric delay is closely related to the weather condition, especially relative humidity, therefore it was estimated that the maximum would be in summer, while reaching its minimum in winter with the apparent seasonal variations. On the contrary, however, the success rate of the ambiguity resolution shows the opposite pattern: its maximum was in winter and minimum in summer. The fact seems to be induced by the surrounding conditions; that is, the trees thick with leaves near the GPS antenna interfere with GPS signals in summer. This seems to confirm partly that there is a distinct trend in the decreasing success rate since 2006 because the trees are growing every year. It is necessary to eliminate the factors that degrade the GPS quality and the tropospheric modeling for Korea needs to be studied further.

• 한국전문물리치료학회지
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• 제16권1호
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• pp.70-78
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• 2009

This study was designed to examine a 3-week modified constraint-induced movement therapy (CIMT) to the less-affected arm of patients with Parkinson's disease (PD) would improve function of the more-affected arm in PD. The subjects were 6 institutional older adults with PD and clients of the social welfare facilities. The subjects (2 men, 4 women) ranged in age from 66 to 90 years (mean age 77.2 yrs). Three clinical tests were used to determine the improvement of functional activity between before and after modified CIMT. The tests included Unified Parkinson's Disease Rating Scale (UPDRS). Wolf Motor Function Test (WMFT), and Action Research Arm Test (ARAT). There were significantly differences after the modified CIMT for time performance in WMFT and pinch in ARAT (p<.05), No significant difference was noted after the modified CIMT for UPDRS and functional ability scale in WMFT. Therefore, the modified CIMT might improve time performance and is available to therapeutic program helping them improve functional ability for upper extremity in Parkinson's disease.

• 약학회지
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• 제45권4호
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• pp.419-425
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• 2001

The neuronal cell death induced by excess glutamate (Glu) has been implicated in many acute and chronic neurodegenerative diseases including cerebral ischemia. Glu-induced elevation of intra-cellular $Ca^{2+}$ plays a critical role in the excitotoxicity, partly through the activation of a variety of $Ca^{2+}$ dependent enzymes. In the present study, we investigated the Glu-induced modulation of $Ca^{2+}$/calmodulin-dependent protein kinase IV (CaMK IV), a multifunctional enzyme abundantly present in the nuclei of neurons. The exposure of cultured rat cortical neurons to $100{\mu}$M Glu for 3 min dramatically increased CaMK IV activity up to 4.5-fold of the control-treated enzyme activity. The activation was very rapid, reaching peak at 3 min and then declined gradually. Under the same experimental conditions, time-dependent acute and delayed neuronal cell death was observed. Immunoblot analyses using specific antibodies showed that the expressions of CaMK IV and $CaMKK_{\alpha}$ were time-dependently modulated by Glu. Taken together, these results imply that the modulation of CaMK IV activity by Glu may be involved in the cascade of events resulting in neuronal cell death in cortical cultures.

• PNF and Movement
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• 제5권2호
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• pp.55-62
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• 2007

Purpose : The purpose of this study was to examine the effects of Rhythmic Stabilization(RS) and Combination of Isotonic(CI) of Proprioceptive Neuromuscular Facilitation on balance in patients with hemiplegia. Methods : Ten patients with hemiplegia were trained with RS and CI for six weeks. Two Standard Scale(TSS), Functional Reach Test(FRT), Time Up and Go test(TUG) and Berg Balance Scale(BBS) were used to prove their improvement of balance. Results : Body weight bearing decreased on less affected side and increased on more affected side. Distance of forward reaching for FRT increased. Time for TUG decreased. BBS score increased. They all showed significant difference. Conclusion : This study suggests that balance training with RS and CI of Proprioceptive Neuromuscular Facilitation improved balance in patients with hemiplegia.

• 한국화재소방학회논문지
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• 제17권1호
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• pp.21-25
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• 2003

본 연구에서는 복사열에 노출된 소방용 방수복의 열적 특성에 대한 실험을 수행하였다. 실험결과 소방용 방수복의 노출시간에 따른 표면의 온도상승은 노출거리가 가까울수록 급격히 일어났다. 또한 복사열유속이 클수록 표면의 온도가 높으며, 정상상태 도달시간은 짧게 나타났다. 소방용 방수복의 노출거리가 멀어질수록 표면의 온도는 급격히 감소하며, 전면과 후면의 온도차도 감소하였다. 복사열유속이 증가할수록 안전노출거리가 증가하였다. 따라서 소방대원의 안전을 위해서는 복사열원으로부터 일정거리이상 떨어져 작업하여야 할 것으로 사료된다.

• Bulletin of the Korean Chemical Society
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• 제26권1호
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• pp.19-31
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• 2005

During the last decade, the exploration of nanoscale device and circuitry based on molecules has gained increasing interest. In parallel with this, considerable effort is being devoted to the development of molecular photonic/electronic materials based on various porphyrin arrays. This involves light as an input/output signal and excitation energy migration as a mechanism for signal transmission. Absorption of a photon at the light collector end of the porphyrin array yields the excited state, which migrates among the intervening pigments until reaching the emitter, whereupon another photon is emitted. As a consequence, it is relevant to understand the excitation energy transfer (EET) processes occurring in various forms of porphyrin arrays for the applications as artificial light harvesting arrays and molecular photonic/electronic wires. Since the excitonic (dipole) and electronic (conjugation) couplings between the adjacent porphyrin moieties in porphyrin arrays govern the EET processes, we have characterized the EET rates of various forms of multiporphyrin arrays (linear, cyclic, and box) based on various time-resolved spectroscopic measurements. We believe that our observations provide a platform for further development of molecular photonic/electronic materials based on porphyrin arrays.

• 천문학회지
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• 제14권2호
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• pp.55-71
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• 1981

On the basis of observational constraints, particularly the relationship between metal abundance and cumulative stellar mass, a simple two-zone disk-halo model for the chemical evolution of our Galaxy was investigated, assuming different chemical processes in the disk and halo and the infall rates of the halo gas defined by the halo evolution. The main results of the present model calculations are: (i) The halo formation requires more than 80% of the initial galactic mass and it takes a period of $2{\sim}3{\times}10^9$ yrs. (ii) The halo evolution is divided into two phases, a fast collapse phase ($t=2{\sim}3{\times}10^8$ yrs) during which period most of the halo stars $({\sim}95%)$ are formed and a later slow collapse phase which is characterized by the chemical enrichment due to the inflow of external matter to the halo. (iii) The disk evolution is also divided into two phases, an active disk formation phase with a time-dependent initial mass function (IMF) up to $t{\approx}6{\times}10^9$ yrs and a later steady slow formation phase with a constant IMF. It is found that at the very early time $t{\approx}5{\times}10^8$ yrs, the metal abundance in the disk is rapidly increased to ${\sim}1/3$ of the present value but the total stellar mass only to ${\sim}10%$ of the present value, finally reaching about 80% of the present values toward the end of the active formation phase.