• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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• v.5 no.2
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• pp.123-132
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• 2007

This study was performed to evaluate the co- and mutual separation for Am, Cm and RE elements from the simulated multi-component solution equivalent to real HLW level by a Zr-DEHPA(di-(2-ethylhexyl) phosphoric acid containing Zirconium)/$NDD(n-dodecane)-HNO_3$ extraction system. Zr-DEHPA was self-synthesized and the optimal condition of (15g/L Zr-1M DEHPA)/NDD-1M $HNO_3$ was selected taking into consideration of prevention of the third phase, and effects of concentration of DEHPA, nitric acid and impregnant amount of Zr on the co-extraction of Am, Cm and RE. In that condition, the extraction yields were 81% (Am), 85% (Cm), more than 80% (RE elements), 98% (Mo), 85% (Fe), 98% (U), 73% (Np), and less than 5% (other elements) so that the system developed for the co-extraction of Am-Cm/RE was proved to be available. For that, however, U, Np, Mo and Fe was elucidated to have to be removed in advance, and Zr inducing the third phase formation was found to be practically excluded. The co-extracted Am-Cm/RE were sequentially separated in an order of Am-Cm (stripping agent : 0.05 M DTPA-1M Lactic acid of pH 3.6)${\rightarrow}RE$ (stripping agent : 5M $HNO_3$), and then their separation factors were evaluated. At above conditions, Am of 65.4%, Cm of 63.9%, RE (except for Y) of more than 85% were stripped.

• Journal of Applied Biological Chemistry
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• v.66
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• pp.114-121
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• 2023

Selective cyclooxygenase (COX)-2 inhibition is a novel strategy to reduce the risk of gastrointestinal side effects caused by conventional nonsteroidal anti-inflammatory drugs. However, some selective COX-2 inhibitors have become apparent to increase the risk of severe cardiovascular disease. The aim of this study was to examine the anti-inflammatory effect of rosemary extract (RE) and confirm the safety of cardiovascular side effects. Inhibition of COX enzyme activity was assessed, and the levels of COX-2 and prostaglandin E₂ (PGE₂) and COX-1 and thromboxane B₂ (TXB₂) were evaluated in lipopolysaccharide (LPS)-induced RAW 264.7 cells. The 40% RE group showed increased COX-2 inhibition activity in a dose-dependent manner, whereas the 50% RE group only exhibited at 100 ㎍/mL. In a cell-based study, COX-2 mRNA expression was similar in both RE groups and PGE₂ levels tended to decrease in the 40% RE group compared to the LPS group in the LPS pretreatment condition. In the LPS posttreatment condition, the COX-2 mRNA expression decreased in the 40% RE group, and PGE₂ levels were increased in the 40 and 50% RE groups. In both conditions, there was no significant difference in COX-1 and TXB₂ levels. In conclusion, 40 and 50% RE showed significant COX-2 inhibition, similar to the positive control group. It was confirmed that the inhibition of the COX-2 expression, but the effect did not affect the balance between prostacyclin and TXB₂. These results indicate that rosemary showed COX-2 inhibition activity with a low risk of cardiovascular diseases.

• Journal of Digital Convergence
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• v.17 no.12
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• pp.229-234
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• 2019

The software market has diversified service needs due to the expansion of the mobile market. To this end, the company intends to produce various apps by extending to the design domain based on the structured architectural assets of the domain market. In this study, we propose an evaluation model that can evaluate the efficiency for servicing assets that reflect the domain characteristics of architecture based on cloud. Based on the characteristics of ISO/IEC 25010 quality model of SQuaRE Series, a software evaluation standard, evaluation model sub-features for evaluating the efficiency of cloud-based asset data were constructed. When the architectural assets were designed as composite assets, they were designed to provide the flexibility of the evaluation model by applying the mandatory and optional evaluation elements of the sub-features that weighted the evaluation items according to the characteristics of the design domain.

• Proceedings of the CALSEC Conference
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• 1999.07b
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• pp.491-500
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• 1999

Recent increase of commercial network Integration to World Wide Web(WWW) shifts an ordinary commerce to electronic environment. This draws more people to examine re-assurance of their secure transaction. This study investigates current status of security methodology for Electronic Payment System and extracts important axis of security level for electronic payment. Using these axis as security evaluation criteria, the research proposes a security matrix which consists of four different level of security granularity, hence allowing evaluation of a nation-wide credit card based payment system. Feasible usage of this matrix contributes to security analysis of the electronic system as whole, hence providing better secured electronic environment.

• Proceedings of the Korean Society of Toxicology Conference
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• 2003.10b
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• pp.89-90
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• 2003

Biological products are composed of vaccines, antitoxin, blood products, DNA recombinant protein drugs, monoclonal antibody, cell therapy and gene therapy. Biological products are divided into traditional (i.e. recombinant proteins and monoclonal antibodies) and novel biological products (gene and cell therapy) and will require a similar re-evaluation of the approaches taken during each development program.(omitted)

• Environmental Engineering Research
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• v.7 no.3
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• pp.159-167
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• 2002

• Journal of the Korean Institute of Intelligent Systems
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• v.12 no.2
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• pp.151-156
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• 2002

There are two methods in evaluation student s achievement. The two evaluation methods are absolute evaluation and relative evaluation. They have much advantages respectively, but also have some limitations such as being too stereotyped or causing overcompetition among learners. This paper suggests a new evaluation method which evaluates student s achievements by considering the score distribution and the frequency The proposed method classifies the scores into several clusters considering the goodness. This approach calculates the goodness by applying the RE(relaxation error), and grades the achievement scores based on the goodness. The suggested method can avoid the problem of grading caused by the narrow gap of scores because it sets a standard for grading by the calculated goodness considering the score distribution and frequency of occurrence. The method can differentiate achievements of a school from those of others, and that it is useful for selecting advanced students and dull ones, and for evaluation of classes based on student s achievement.

• The Korea Journal of Herbology
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• v.31 no.5
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• pp.85-92
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• 2016

Objectives： This study is experimental comparison of brown rice (BR) and germinated brown rice (GBR) on upper gastrointestinal diseases animal models.Methods： The ICR mice were divided randomly into four groups of six animals each (Normal mice, gastritis mice, gastritis mice treated with BR, gastritis mice treated with 48h GBR). Gastritis was induced by administration of 0.5 mL 150 mM HCl-60% ethanol. Six-week-old male Sprague-Dawley (SD) rats were randomly divided into 7 groups after 1 week adaptation. (Normal rat, reflux esophagitis (RE) rat, RE rat treated with BR, RE rat treated with 24,30,36,48h GBR). Reflux esophagitis was induced by ligation with a 2-0 silk thread both the pylorus and the transitional junction between the forestomach and the corpus in SD rats.Results： HCl/ethanol-induced gastric mucosal injury mice were ameliorated mucosal damage upon histological evaluation by treatment of 48h GBR than BR. Optical changes such as hyperemia and multiple erosions were observed in the rats with RE and damage to the normal rats was not apparent. The oral administration of GBR significantly diminished against gross mucosal damage in a germination time-dependent manner. Also, the administration of GBR suppressed the biomarker of oxidative stress, reactive oxygen species (ROS) and produces peroxynitrite (ONOO-) in serum. However, the administration of GBR could not affect to the pH level secreted from stomach when compared with Control group.Conclusions： These findings suggest that GBR could have improving effects on upper gastrointestinal diseases in a germination time-dependent manner.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.50 no.3
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• pp.244-251
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• 2014

This paper describes a prototype mechanical white noise generator has a source level of more than 170.0 dB (re $1{\mu}Pa$ at 1 m) at the frequency range of 10 Hz to 100 kHz. The results of performance evaluation of the generator are as follows. The average source level of the generator measured by a step of $15^{\circ}$ in horizontal (0 to $360^{\circ}$, 25 points) was 185.2 (SD (standard deviation): 2.3) dB (re $1{\mu}Pa$ at 1 m). The maximum and minimum source levels were appeared at the frequency range of 2.5 to 5.0 kHz and around 100 kHz, respectively. The average source levels at $0^{\circ}$, $90^{\circ}$, $180^{\circ}$ and $270^{\circ}$ were 162.9 (SD: 10.6), 168.4 (SD: 10.0), 162.1 (SD: 9.1) and 166.5 (SD: 11.1) dB (re $1{\mu}Pa$ at 1 m). The average source level measured by a step of $30^{\circ}$ in vertical was 184.9 (SD: 2.2) dB (re $1{\mu}Pa$ at 1 m). The relative maximum variation width of the source levels in horizontal and in vertical measurement were less than 7.0 dB and 1.0 dB, respectively.

• Parasites, Hosts and Diseases
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• v.56 no.6
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• pp.531-543
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• 2018

Historically, Plasmodium vivax malaria has been one of the most highly endemic parasitic diseases in the Korean Peninsula. Until the 1970s, vivax malaria was rarely directly lethal and was controlled through the Korean Government Program administered by the National Malaria Eradication Service in association with the World Health Organization's Global Malaria Eradication Program. Vivax malaria has re-emerged in 1993 near the Demilitarized Zone between South and North Korea and has since become an endemic infectious disease that now poses a serious public health threat through local transmission in the Republic of Korea. This review presents major lessons learned from past and current malaria research, including epidemiological and biological characteristics of the re-emergent disease, and considers some interesting patterns of diversity. Among other features, this review highlights temporal changes in the genetic makeup of the parasitic population, patient demographic features, and spatial distribution of cases, which all provide insight into the factors contributing to local transmission. The data indicate that vivax malaria in Korea is not expanding exponentially. However, continued surveillance is needed to prevent future resurgence.