• Korean Journal of Fisheries and Aquatic Sciences
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• v.50 no.2
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• pp.219-221
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• 2017

In 2015, white cottony tufts were observed on gametophytes of the kelp Saccharina japonica. Wet mount and histopathology examination revealed numerous fungal hyphae and mycelium around the gametophytes. The gametophytes surrounded by fungal hyphae were generally round and empty. A specific 610-bp fragment of the internal transcribed spacer (ITS)-5.8S rDNA-ITS gene of fungi was amplified by polymerase chain reaction and the nucleotide sequence showed 100% identity with those of Acremonium sclerotigenum, Acremonium sp. and Ascomycota sp. When fungus-infected gametophytes were mixed with healthy gametophytes, a high transmission rate (100%) resulted. This is the first report of mycosis of gametophytes in Korea.

• Transactions of the Korean Society of Automotive Engineers
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• v.20 no.5
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• pp.95-101
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• 2012

An electric water pump for engine cooling system has an advantage which particularly in the cold start, the use of the electric water pump saves fuel and leads to a corresponding reduction in emissions. The canned type electric water pump without mechanical sealing elements was selected to meet the requirements for operational reliability and life. However, the electric water pump for internal combustion engine generates much more heat loss than for hybrid electric vehicle since it is operated by the electric power of high current and low voltage. In this study, the fluid flow and thermal characteristics of the canned type electric water pump as an inverter integrated water pump has been investigated under the effects of heat generation. The analysis conditions such as outdoor air temperature of $125^{\circ}C$, water pump speed of 6000 rpm, coolant temperature of $106^{\circ}C$ and coolant flow rate of 120 L/min was used as a standard condition. Therefore, flow fields and temperature distribution inside the water pump were obtained. Also, we checked the feasibility of the canned type for the electric water pump in comparison with the mechanical seal type.

• ETRI Journal
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• v.43 no.4
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• pp.660-673
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• 2021

To efficiently use frequency resources, the next 6th generation mobile communication technology must solve the problem of out-of-band emission (OoBE) of cyclic prefix (CP) orthogonal frequency division multiplexing (OFDM), which is not solved in 5th generation technology. This study describes a new zero insertion technique to replace an existing filtering scheme to solve this internal problem in OFDM signals. In the development of the proposed scheme, a precoder with a two-dimensional structure is first designed by generating a two-dimensional mapper and using the specialty of each matrix. A spectral shaping technique based on zero insertion instead of a long filter is proposed, so it can be applied not only to long OFDM symbols, but also very short ones. The proposed method shows that the transmitted signal is completely blocked at the bandwidth boundaries of signals according to the current standards, and it is confirmed that the proposed scheme is ideal with respect to bit error rate (BER) performance because its BER is the same as that of CP-OFDM. In addition, the proposed scheme can transformed into a real time structure through vectorizing process with minimal complexity.

• Korean Journal of Metals and Materials
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• v.49 no.2
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• pp.145-152
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• 2011

Mechanical and property corrosion resistance of Mg-Zn-Y alloys with an atomic ratio of Zn/Y of 6.8 are investigated using optical microscopy, scanning electron microscopy, transmission electron microscopy, uniaxial tensile test and corrosion test with immersion and dynamic potentiometric tests. The alloys showed an in-situ composite microstructure consisting of ${\alpha}$-Mg and icosahedral phase (I-phase) as a strengthening phase. As the volume fraction of the I-phase increases, the yield and tensile strengths of the alloys increase while maintaining large elongation (26~30%), indicating that I-phase is effective for strengthening and forms a stable interface with surrounding ${\alpha}$-Mg matrix. The presence of I-phase having higher corrosion potential than ${\alpha}$-Mg, decreased the corrosion rate of the cast alloy up to I-phase volume fraction of 3.7%. However further increase in the volume fraction of the I-phase deteriorates the corrosion resistance due to enhanced internal galvanic corrosion cell between ${\alpha}$-Mg and I-phase.

• Journal of Neurocritical Care
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• v.7 no.2
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• pp.104-110
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• 2014

Background: Cefepime is a fourth-generation cephalosporin widely used for empiric treatment of severe infections. Neurotoxicity by cefepime have been reported due to γ-aminobutyric acid A receptor inhibition or other mechanisms. The aim of this study was to evaluate the risk factors for cefepime-induced neurotoxicity between group showing cefepime-induced neurotoxicity and group without neurotoxicity. Methods: From Jan 2005 to June 2010, a total of 2,461 patients (older than 20) who used cefepime were considered in this study. We compared patients who developed cefepime-induced neurotoxicity (patient group, n=21) to patients who had no cefepime-induced neurotoxicity (control group, n=31). We analyzed demographic, underlying diseases, and metabolic parameters before cefepime treatment and during cefepime treatment between the two groups. Statistical analysis was performed using SPSS 18 software. Results: Of the total 2461 patients, 21 (0.85%) were diagnosed with cefepime-induced neurotoxicity. Impaired glomerular filtration rate (GFR at 15-30 ml/min) before cefepime use were significantly (P<0.05) higher risk for developing cefepime-induced neurotoxicity in patient group compared to that in the control group. Age, sex, and other metabolic parameters except GFR before and during, usage of cefepime did not show any statistical difference between the two groups. Conclusion: The present study revealed that cefepime-induced neurotoxicity was prone to develop in patients with impaired renal function before cefepime usage.

• Tuberculosis and Respiratory Diseases
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• v.81 no.1
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• pp.29-41
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• 2018

Lung cancer is one of the most commonly diagnosed cancers and the leading cause of cancer-related deaths worldwide. Although progress in the treatment of advanced non-small cell lung cancer (NSCLC) has been made over the past decade, the 5-year survival rate in patients with lung cancer remains only 10%-20%. Obviously, new therapeutic options are required for patients with advanced NSCLC and unmet medical needs. Cancer immunotherapy is an evolving treatment modality that uses a patient's own immune systems to fight cancer. Theoretically, cancer immunotherapy can result in long-term cancer remission and may not cause the same side effects as chemotherapy and radiation. Immunooncology has become an important focus of basic research as well as clinical trials for the treatment of NSCLC. Immune checkpoint inhibitors are the most promising approach for cancer immunotherapy and they have become the standard of care for patients with advanced NSCLC. This review summarizes basic tumor immunology and the relevant clinical data on immunotherapeutic approaches, especially immune checkpoint inhibitors in NSCLC.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.26 no.6
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• pp.257-262
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• 2014

This paper describes an experimental study for heating performance that can be used in R-134a automobile heat pump systems. The heat pump system is widely studied for heating system in zero-emission vehicles to attain both the small power consumption and the effective heating of the cabin. This paper presents the experimental results of the influence on heating capacity and coefficient of performance of heat pump system. Tests were performed with different sizes of internal and external heat exchangers, and refrigerant flow rate was also considered in two-way flow devices. In addition, the heat, air, and water sources with the heat pump system were examined. The experimental results with the heat pump system were used to analyze the impact on performances. The best combination of performance was A-inside heat exchanger, B-outside heat exchanger, and B-flow device, respectively. In addition, a water heat-source was found to give roughly 40% of better performance than an air heat-source heat pump system.

• Mass Spectrometry Letters
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• v.2 no.1
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• pp.24-27
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• 2011

Hyperthermal ion/surface collisions of bromotoluene radical cations were studied using perfluorinated (F-SAM) and hydroxyl-terminated (OH-SAM) self-assembled monolayer surfaces in a tandem mass spectrometer with BEEQ geometry. The isomers were differentiated by ion abundance ratios taken from surface-induced dissociation (SID). The dissociation rate followed the order of ortho > meta > para isomers. The peak abundance ratio of m/z 51 to m/z 65 showed the best result to discern the isomers. A dissociation channel leading to tolylium ion was suggested to be responsible for the pronounced isomeric differences. The capability of SID to provide high-energy activation with narrow internal energy distribution may have channeled the reaction into the specific dissociation pathway, also facilitating small differences in reaction rates to be effective in the spectral time window of this experiment. All of the molecular ions experiencing reactive collisions with the F-SAM surface undergo transhalogenation, in which a fluorine atom on the surface replaces the bromine in the incoming ions. This reactive collision was dependent on the laboratory collision energy occurring in ca. 40.75 eV range.

• Journal of the Korean Society of Marine Environment & Safety
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• v.25 no.3
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• pp.373-380
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• 2019

In this paper, a pico hydro turbine employing low head circulation water at fish farms is designed and evaluated. Due to the advantages of simple structures, small head requirements, and low-cost investment, the constant thickness propeller turbine is considered as a feasible solution. The design process based on the free vortex method is presented in full detail, and a 4-blade runner is built using BladeGen. The turbine performance is analyzed both numerically and via experimental methods. Despite slight differences, the results show similar trends between CFD simulations and experiments carried out on factory test-rigs in a wide range of working conditions. At the design flow rate, the turbine achieves the best efficiency of 70 %, generating 3.5 kW power when rotating at 420 rpm. The internal flow field, as well as the turbine's behavior, are investigated through the distribution of blade streamlines, pressure, and velocity around the runner. Moreover, the pressure coefficient on the blade surface at 3 span positions is plotted while the head loss for each simulation domain is calculated and displayed by charts.

• JSTS:Journal of Semiconductor Technology and Science
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• v.13 no.5
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• pp.430-442
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• 2013

This paper presents a fast multi-reference frame integer motion estimator for H.264/AVC. The proposed system uses the previously proposed fast multi-reference frame algorithm. The previously proposed algorithm executes a full search area motion estimation in reference frames 0 and 1. After that, the search areas of motion estimation in reference frames 2, 3 and 4 are minimized by a linear relationship between the motion vector and the distances from the current frame to the reference frames. For hardware implementation, the modified algorithm optimizes the search area, reduces the overlapping search area and modifies a division equation. Because the search area is reduced, the amount of computation is reduced by 58.7%. In experimental results, the modified algorithm shows an increase of bit-rate in 0.36% when compared with the five reference frame standard. The pipeline structure and the memory controller are also adopted for real-time video encoding. The proposed system is implemented using 0.13 um CMOS technology, and the gate count is 1089K with 6.50 KB of internal SRAM. It can encode a Full HD video ($1920{\times}1080P@30Hz$) in real-time at a 135 MHz clock speed with 5 reference frames.