• Title/Summary/Keyword: rate dependent

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Effects of High-Intensive Exercise Duration on Hematologic Properties and Cytokines in Rats (고강도운동 지속시간이 rat의 혈액학적 조성과 사이토카인에 미치는 영향)

  • Hyun, Kyung-Yae
    • Journal of Life Science
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    • v.21 no.7
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    • pp.1039-1045
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    • 2011
  • The effects of duration and time-dependent, high-intensity exercise on hematological properties and inflammation-related parameters in rats were studied. 20, 60, and 120 min of high-intensive exercise were performed daily for 8 weeks. None of the complete blood count (CBC) factors were affected by the exercise, except for the leukocyte concentration which, in the 20 min group, showed an increase of 47% compared to the control, but this was decreased after 60 min by 30% compared to the control. As exercise was performed for 60 min or longer, serum concentrations of $Fe^{++}$, unsaturated iron biding capacity (UIBC), and total iron biding capacity (TIBC) were significantly elevated in comparison to the control, where 20 min of exercise did not show any change. Both levels of interleukin-6 (IL-6), a pro-inflammatory cytokine, and interleukin-10 (IL-10), an anti-inflammatory cytokine in the serum, were elevated in response to the high-intensity exercise, however the rate of IL-6 increase was higher than the rate of exercise intensity increase, thus the offset of inflammation might be suggested. The concentration of nitric oxide (NO) in the serum became high in response to the exercise. Overall, the current observation suggests that inflammation-like responses to high-intensity exercise might be due to high circulation of blood flow and high oxygen requirement, resulting in systemic damages. However, under the current high-intensity exercise conditions, more than 20 min of exercise might not be suggested for health care purposes.

Implementation and Evaluation of the LUTS Diagnosis System Using FPGA (FPGA를 이용한 LUTS 진단 시스템 구현 및 평가)

  • Jeong, Do-Un;Chung, Wan-Young;Jeon, Gye-Rock
    • Journal of the Institute of Convergence Signal Processing
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    • v.8 no.1
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    • pp.6-14
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    • 2007
  • The purpose of urodynamic investigation is to determine information on the function of the urinary system. One of the most frequently used measurement procedures in urodynamics is filling and voiding cystometry using invasive method. But in this method transurethral catheter is use and it makes patients uncomfortable. The aim of this study was to implement the system that could evaluate the function of urinary tract with noninvasive and comfortable method. Therefor in this study, a sensor and measuring system were implemented to measure uroflow, urophonography and noninvasive bladder pressure signal during urination for diagnosing the LUTS(lower urinary tract symptoms) using noninvasive method. The implemented system compose of the sensor parts, signal conditioning parts, system control parts using FPGA and PC monitoring program. For the evaluation of the implemented system, the simulation of system's control part was performed and the model system for the lower urinary system was designed. From the evaluation of the model system, the mean error rate of the uroflow measurement part was 1.08% and coefficient of variation was 1,48. And the mean error rate of the noninvasive bladder pressure measurement part was 2.41% and coefficient of variation was 2.81. urophongraphy signal analysis was accomplished in a time domain and frequency domain. Average RMS power was used in a time domain analysis, and MF was used in a frequency domain analysis. From the evaluation of the model system average RMS power and MF was dependent on the occlusion degree significantly and median frequency range of $60{\sim}160Hz$ was correlated with the occlusion.

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Shear-Rate Dependent Ring-Shear Characteristics of the Waste Materials of the Imgi Mine in Busan (부산 임기광산 광미의 전단속도에 따른 링 전단특성 연구)

  • Jeong, Sueng-Won;Ji, Sang-Woo;Yim, Gil-Jae
    • Journal of the Korean Geotechnical Society
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    • v.30 no.7
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    • pp.5-15
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    • 2014
  • Abandoned mine deposits are exposed to various physico-chemical geo-environmental hazards and disasters, such as acid mine drainage, water contamination, erosion, and landslides. This paper presents the ring shear characteristics of waste materials. The ring shear box with a rotatable O-ring was used in this study. Three tests were performed: (i) Shear stress-time relationship for given normal stress and shear speed, (ii) shear stress as a function of shear speed, and (iii) shear stress as a function of normal stress. For a given normal stress (50 kPa) and speed (0.1 mm/sec), the materials tested exhibit a strain softening behavior, regardless of drainage condition. The peak and residual shear stresses were determined for each normal stress and shear speed. The shear stress was measured when shear speed is equal to 0.01, 0.1, 1, 10, 50, 100 mm/sec or when normal stress is equal to 20, 40, 60, 80, 100, 150 kPa. From the test results, we found that the shear stress increases with increasing shear speed. The shear stress also increases with increasing normal stress. However, different types of shearing mode were observed in drained and undrained conditions. Under drained condition, particle crushing was observed from the shearing zone to the bottom of lower ring. Under undrained condition, particle crushing was observed only at the shearing zone, which has approximately 1 cm thick. It means that a significant high shear speed under undrained condition can result in increased landslide hazard.

The Relationship between Medical Service Quality and Managerial Performance in General Hospitals (종합병원의 의료서비스 품질수준과 경영성과 간의 관계)

  • Ryu, Chung-Kul;Yang, Dong-Hyun
    • Korea Journal of Hospital Management
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    • v.11 no.4
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    • pp.82-103
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    • 2006
  • The purpose of this study is to analyse statistically the relation between medical service quality and managerial performance. And then the way of analysis is the regression analysis that independent variable is service quality, dependent variable is the volume of revenue, the number of patients and the rate of beds utility, and dummy variable is the number of beds, ownership and region. The sample hospitals were the 113 hospitals on general hospitals more than 300beds which were consisted of 20 public hospitals, 41 corporate hospitals and 52 college hospitals, and also distributed 67 hospitals on big city and 46 hospitals other city. The sample hospitals were selected from the Korean Hospital Association and the data of the year 2003 and 2004. The collected data was analyzed using the SPSSWIN 10.0 version, and the study hypothesis was tested using regression analysis. The findings of this study are summarized as follows. First, as a result of analysing hypothesis 1. In the study of the relationship between the service quality and the revenue, it was verified that the more service quality in last year became the more revenue in the year. But the dummy variable, ownership and region, rarely related to hospital revenue. Therefore it means that the more service quality is connected to the more revenue on the large number of beds hospitals. Second, as a result of analysing hypothesis 2 & 3. In the study of the relationship between the service quality and the number of patients, it was verified that the more service quality in last year became the more outpatients in the year. But there was no verified to inpatients. It seems to be the reason why a hospital has operated the fixed number of beds approved by the public office. So there are no free to expand beds according to the number of inpatients as much as inpatients are increasing. Third, as a result of analysing hypothesis 4 & 5. In the study of the relationship between the service quality and the rate of beds utility, it was verified that the more service quality in last year became the shorter of average stay of length in the year. Especially it has influenced much more on a hospital which was the large number of beds, the corporate and the college, but the region. But it was denied that the more service quality became the more the beds turnover. As a result of this study, it shows that the service quality in the last year has importantly influenced on a hospital managerial performance in the year. Estimating the service quality of each hospital, most patients have selected the hospital they want. And the hospital need to keep the number of patients for the proper management. So this result of the study means that a hospital must improve the service quality for keeping efficient management.

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Evaluation of Neutron Flux Distributions of SMART-P IST Region for the Design of Ex-Core Detector (SMART 연구로 노외계측기 설계를 위한 IST 영역의 중성자속 분포 평가)

  • Koo, Bon-Seung;Kim, Kyo-Youn;Lee, Chung-Chan;Zee, Sung-Quun
    • Journal of Radiation Protection and Research
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    • v.30 no.2
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    • pp.55-60
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    • 2005
  • The evaluation of neutron flux distribution was performed for the ex-core detector design of SMART-P. DORT and MCNP code were used for the calculation of energy-dependent neutron flux distribution at 100% full power condition. Two code results show that maximum thermal flux appears at the $1^{st}$ water region in IST region and agree within 10% difference. In addition, another evaluation was performed code with assumptions that cote was composed of fission source and control rod without fuel assemblies. These assumptions make neutron count rate to be minimized. As a results, maximum thermal flux showed $6.99{\times}10^{-2}(n/cm^2-sec)$, when the strength of initial fission source was assumed as $1.0{\times}10^8(n/sec)$. The main reason of these results is due to the thermalization of fast neutrons in the water region and thermal flux is proportional to 80% of total neutron flux. Therefore, optimization of filler material of detector guide tube, position of installation and axial length of detector segments is necessary for the design of ex-core detector to enhance the neutron count rate and above results could be used in ex-core detector design as a fluence requirement.

Effects of $17\beta-Estradiol$ on the Sex Reversal of Nile Tilapia, Oreochromis niloticus ($17\beta-Estradiol$에 의한 나일틸라피아(Oreochromis niloticus)의 성전환)

  • KIM Dong Soo;JO Jae-Yoon;BANG In Chul
    • Journal of Aquaculture
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    • v.6 no.2
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    • pp.125-132
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    • 1993
  • To determine the effective dose of $17\beta-estradiol$ on the production of all female populations of Nile tilapia, Oreochromis niloticus, the first feeding-stage larvae were fed 0, 60, 120, 240 and 480 ppm of $17\beta-estradiol$ in the diet for 30 days. Rates of sex reversal, survival and growth of each treated group were analyzed. Effects of 3 different treatment durations, 10, 20 and 30 days, treated with 480 ppm $17\beta-estradiol$ in the diet to produce all females, were also evaluated. The incidence of female fish were clearly dose and time dependent. The female induction rate of 0, 60, 120, 240 and 480 ppm were 47.5, 86.4, 91.3, 97.0 and $100\%$, respectively. Female induction rates of 480 ppm treated for 10, 20 and 30 days were 64.2, 84.3 and $100\%$ respectively. The survival rate of each treated group was not different from the control, and the growth rates of the treatment groups decreased as the treatment duration and the concentration of the estrogen hormone increased.

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Quality Characteristics and Antioxidative Effect of Cookies Made with Capsosiphon fulvescens Powder (매생이 분말을 첨가하여 제조한 쿠키의 품질특성과 항산화효과)

  • Lee, Ga-Wha;Choi, Min-Ja;Jung, Bok-Mi
    • Korean journal of food and cookery science
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    • v.26 no.4
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    • pp.381-389
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    • 2010
  • In this study, we investigated the quality characteristics of cookies containing mesangi powder (MP). The cookies were stored at 30 $^{\circ}C$ for 28 days. The pH of the dough decreased significantly upon the addition of MP. The spread factor of the cookies also decreased significantly with more MP added to the cookie recipe. The loss rate of cookies was significantly higher in 3% and 5% cookies than in control and 7% cookies. The leavening rate was significantly decreased upon the addition of MP. Hardness was significantly higher in 5% and 7% cookies than in control cookies. The L, a, b values of cookies were significantly reduced at higher MP content. The results of sensory evaluation showed that cookies made with MP did not differ significantly from the control, except in color and moistness. The mineral contents of cookies increased in dose-dependent fashion with MP concentration. The acid and peroxide values were lower in cookies with 5% MP than other cookies.

Effect of Ascidian Tunic Extracts on Cholesterol Accumulation and Pigmentation of Kuruma Prawn, Penaeus japonicus (우렁쉥이 껍질 추출물이 보리새우 Cholesterol 축척 및 착색에 미치는 영향)

  • CHOI Byeong-Dae;KANG Seok-Joong;LEE Kang-Ho
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.29 no.3
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    • pp.393-408
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    • 1996
  • The effect of various levels of ascidian tunic extracts and carophyll pink on the growth rate, pigmentation, lipid and total cholesterol accumulation, and fatty acid compositions were studied in kuruma prawn, Penaeus japonicus. The kuruma prawn was fed the purified diets with or without ascidian tunic extract and carophyll pink at the levels of 100, 200, and 400 ppm for 8 weeks. In the experiment diet with ascidian tunic extracts or carophyll pink, the values of daily growth rate were ranged between $1.065\;to\;1.292%$, compared with control group. The content of astaxanthin in kuruma prawn was not significantly affected by the feeding levels of tunic extracts. Feeding of the tunic extracts, on the other hand, increased the kuruma prawn lipid and total cholesterol content, and pigment deposition in concentration-dependent manners without influencing the free astaxanthin concentration of prawn flesh and heads between two feeding groups(200 and 400 ppm). And it was also demonstrated that the dietary astaxanthin was deposited in kuruma prawn body tissue mainly as astaxanthin esters. The results suggest that the best feeding strategy for pigmentation in kuruma prawns is the diets with ascidian tunic extracts at the level of 4g/kg feed (200 ppm) for 8 weeks.

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Adverse Effects of the Megadose Perilla Oil on the Rats Metabolism (들깨기름을 다량 투여한 흰쥐에서 대사에 미치는 역작용에 관하여)

  • 서화중;서유승
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.31 no.2
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    • pp.277-283
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    • 2002
  • In the present study, adverse effects of megadose of dietary perilla oil were investigated in an experimental model consisted of 6 groups of Wistar rats. To compare the adverse effects of megadose perilla oil with different kind of dietary fat, rats were fed one of the following diets for one month: 10% beef tallow (B$_1$B), 10% corn oil (C$_1$B), 10% perilla oil (P$_1$B), 20% beef tallow (B$_2$B), 20% corn oil (C$_2$B), and 20% perilla oil (P$_2$B) diet. The body weight gain rate seemed to be more affected by the size of fat contents than the species of fat in the diet, so the body weight gain rate of 20% fat groups were significantly higher than those of 10% fat groups in spite of the larger amount of flood intake in 10% fat groups than in 20% fat groups. The levers of plasma triglyceride and total-cholesterol in 20% fat groups were significantly increased in dose dependent fashion when compared to 10% groups, the values of beef tallow (B$_2$B) group being the highest among all groups. Plasma glutainic pyruvic transferase activities and level of blood urea nitrogen had a tendency to increase along with increase of fat contents (%) in diets, the values of P$_2$B group, the highest among all groups, being beyond the normal levers. The plasma carbon dioxide concentration of P$_2$B group was the highest in all groups and exceeded the normal value, there being no significant difference among the plasma carbon dioxide concentration of others groups. The results showed that large dose and long term intake of dietary perilla oil had some adverse effects on hepatic and other organic functions in rats.

The Prediction Model of Carbonation Process by CO2 Diffusion Using the Air Permeability Coefficient for Concrete (콘크리트의 투기계수를 이용한 CO2확산 탄산화진행 예측모델)

  • Kang, Suk-Pyo;Kim, Young-Sun;Song, Ha-Won;Kim, Gyu-Yong
    • Journal of the Korea Concrete Institute
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    • v.22 no.2
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    • pp.209-217
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    • 2010
  • Recently, some mathematical models for the prediction on progress of carbonation of concrete were reported. These models take account for $CO_2$ diffusion and chemical reaction between $Ca(OH)_2$ and $CO_2$. Based on the assumption that $CO_2$ diffuses in the carbonation zone and reacts with $Ca(OH)_2$ at the outer face of carbonation zone and non-carbonation zone. In this study, a mathematical model to predict the progress of carbonation of concrete has been established based on the reducing concentration of $Ca(OH)_2$ in the carbonation progress zone, where $Ca(OH)_2$ reacts with $CO_2$ and $Ca(OH)_2$ and $CaCO_3$ coexist. Also, the prediction model of carbonation progress rate of concrete using the air permeability coefficient regarding to $CO_2$ diffusion is developed. As a result of this study, an expression, the model equation is obtained for the prediction of carbonation based on the time and interaction velocity between $CO_2$ and Ca(OH)$_2$ dependent air permeability coefficient. The prediction by the model satisfied the experimental data of the accelerated carbonation for painted concrete. Consequently, the model can predict the rate of carbonation and the potential service life of concrete structure exposed to atmosphere.