• Title/Summary/Keyword: rate dependent

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Effect of Progressive Muscle Relaxation using Biofeedback on Perceived Stress, Stress Response, Immune Response and Climacteric Symptoms of Middle-Aged Women (바이오피드백을 이용한 점진적 근육이완이 중년여성의 지각된 스트레스, 스트레스반응, 면역반응 및 갱년기 증상에 미치는 효과)

  • 정인숙
    • Journal of Korean Academy of Nursing
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    • v.34 no.2
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    • pp.213-224
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    • 2004
  • Purpose: This study was aimed to evaluate the effect of progressive muscle relaxation training using biofeedback on perceived stress, stress response, immune response and climacteric symptoms, Method: This was a crossover, pre-post test design, The study subjects are 36 middle-aged women who were selected at 2 public health centers, The independent variable was Biofeedback training for 4 weeks, twice a week and home training for 4 weeks, Dependent variables were perceived stress, stress response, immune response, and climacteric symptoms measured with Hildtch's scale (1996), Result: Progressive muscle relaxation training using biofeedback was not effective in reducing perceived stress, but it was shown to be effective in reducing physiological stress responses such as pulse rate and EMG, Though blood pressure and skin conductance were repeatedly down, and skin temperature slowly increased, there were no statistically significant differences. Progressive muscle relaxation training using biofeedback was not effective in reducing serum cortisol, enhancing immune responses, or decreasing climacteric symptoms. Conclusion: The findings point to a pressing need for further, well-controlled and designed research with consideration in selection of subjects and instruments, frequency of measurements, the sampling method, and intervention modalities.

Novel p104 protein regulates cell proliferation through PI3K inhibition and p27Kip1 expression

  • Han, Seung-Jin;Lee, Jung-Hyun;Choi, Ki-Young;Hong, Seung-Hwan
    • BMB Reports
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    • v.43 no.3
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    • pp.199-204
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    • 2010
  • The protein p104 was first isolated as a binding partner of the Src homology domain of phospholipase C$\gamma$1, and has been shown to associate with p85$\alpha$, Grb2. The ectopic expression of p104 reduced cellular growth rate, which was also achieved with the overexpression of only the proline-rich region of p104. The proline-rich region of p104 has been found to inhibit the colony formation of platelet-derived growth factor BB-stimulated NIH3T3 cells and MCF7 cancer cells on soft agar. Mutagenesis analysis showed that the second and third proline-rich regions are essential for growth control, as well as for interaction with p85$\alpha$. Overexpression of p104 increased the level of the cyclin-dependent kinase inhibitor, $p27^{Kip1}$, and inhibited the activity of phosphoinositide 3-kinase (PI3K). In summary, p104 interacts with p85$\alpha$ and is involved in the regulation of $p27^{Kip1}$ expression for the reduction of cellular proliferation.

Assessment of Material Properties Using Finite Element Analysis for Small Punch Creep Testing (SP 크리프 시험의 유한요소해석을 이용한 재료물성 평가)

  • Park, Tae-Kyu;Ma, Young-Wha;Yoon, Kee-Bong;Jeong, Ill-Seok
    • Proceedings of the KSME Conference
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    • 2001.06a
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    • pp.511-516
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    • 2001
  • Recently small punch creep testing (or miniature disc bend creep test) has received much attention through European collaborative research projects. This method was considered as a substitute for the conventional creep rupture testing by which the residual creep life is measured from the specimen taken out from serviced components of high temperature plants. It would be beneficial if the material creep properties such as power law creep constants as well as the creep rupture life can be measured from the small punch creep test. In this paper a method of assessing creep constants from the small punch creep testing is proposed. Finite element analyses were performed to investigate evolution of stress and strain rate at the weakest locations of the small punch creep specimen. Elastic-plastic-secondary creep analyses were carried out. The estimation equations for creep constants by the small punch creep testing are proposed based on the finite analysis results. Small punch creep tests were also performed with 9Cr steel and the accuracy of the proposed equation was verified by the experimental results.

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Analysis on the solute redistribution in coarsening dendrite arms during solidification of binary metal alloys (수지상가지의 조대화를 고려한 이원합금의 응고과정동안 용질 재분배 해석)

  • Yu, Ho-Seon
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.20 no.4
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    • pp.1437-1448
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    • 1996
  • This paper presents a simplified model for approximate analysis of the solute redistribution in coarsening dendrite arms during solidification of binary metal alloys. By introducing a quadratic concentration profile with a time-dependent coefficient, the integral equation for diffusion in the solid phase is reduced to a simple differential relation between the coefficient and the solid-liquid interface position. The solid fraction corresponding to the system temperature is readily determined from the relation, phase equilibrium and the overall solute balance in which the liquid phase is assumed to be completely mixed. In order to validate the developed model, calculations are performed for the directional solidification of Al-4.9 mass Cu alloy. The predicted eutectic fractions for a wide range of the cooling rate reasonably agree with data from the well-known experiment as well as sophisticated numerical analyses. Also, the results for the back diffusion limits are consistent with available references. Additional calculations show that the characteristic parameters such as the coarsening, density variation and nonlinarity in the phase diagram significantly affect the microsegregation. Owing to the simplicity, efficiency and compatibility, the present model may be suitable for the micro-macroscopic solidification model as a microscopic component.

Dynamic Behavior of Rotating Shaft System Corresponding to Operating Modes (운전모드에 따른 회전축계의 동적거동)

  • Kim, Sang-Hwan
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.20 no.9
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    • pp.2744-2751
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    • 1996
  • In case of limited power supply, a rotating shaft system may not reach its operating speed that is greater than its critical speed, but the speed oscillates with small ampllitude near critical speed. As a result, it is considered that the operating mode plays an important role in the smooth start of machines. In order to investigate the dynamic behaviors of the rotating shaft system at the beginning stage, one has derived the equations of motion whose degrees of freedom is three, two translations and one rotation. The simultaneous differential equations are numerically solved by using runge-Kutta method, and thus the small time step length could be required corresponding to the stability of solution. Three types of operating modes dependent upon the driving torque rate have been numerically investigated according to the maximum displacement of shaft center. The first type of relation is linear, the second type is composed of two linear curves recommended by machine manufacturer, and the last one is the proposed torque curve reflecting the frequency response curve of one degree of freedom system. For the second type of modes, it is found that the optimal range of intermediate speed to the critical speed lies between 0.8 and 0.9. In addition to that, the maximum displacement can be reduced more if the third type of mode is utilized.

Fatigue Crack Growth Behavior of Ni-Cr-Mo Steel under Acid Fog Environment (산성안개 환경하에서 Ni-Cr-Mo 강의 피로크랙전파거동)

  • Kim, Min-Geon;Im, Yong-Ho;Kim, Man-Gu
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.24 no.7 s.178
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    • pp.1841-1846
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    • 2000
  • To examine the effect of acid fog on the corrosion fatigue behavior in structural steel, fatigue tests under acid fog atmosphere were carried out in comparison with distilled water. The corrosive c omponents contained in acid fog pile up the corrosion products on crack face and show a crack branching and crack tip blunting. Therefore, due to these workings crack growth rate was reduced by decreasing the effective stress range in crack tip rather than under distilled water. Also the effect of sulfuric acid, which is the main component of acid fog, and testing speed on fatigue crack growth were examined. It was found that corrosion behavior was remarkably dependent upon pH and Hz rather than components of acid fog. According as pH and testing speed decrease below a specific value, crack growth was accelerated in comparison with distilled water. This reveals that due to liquid having strong acidity and slow speed of test the crack face dissolution was promoted, so crack closure was disturbed in the process of stress descent.

Effects of Morphology and Rheology on Neo-fructosyltransferase Production by Penicillium citrinum

  • Lim, Jung-Soo;Lee, Jong-Ho;Kim, Jung-Mo;Park, Seung-Won;Kim, Seung-Wook
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.11 no.2
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    • pp.100-104
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    • 2006
  • In this study, we investigated the relationship between the morphology and the rheological properties of Penicillium citrinum to improve the production of neo-fructosyltransferase (neo-FTase). In a 2.5 L bioreactor culture of P. citrinum, it was observed that agitation speed and aeration rate had significant effects on the production of neo-FTase and that maximum cell mass and neo-FTase production obtained at 500 rpm and 1.5vvm were 8.14 g/L and $53.2{\times}10^{-3} U/mL$, respectively. Cell mass and neo-FTase production increased to 91.53 and 25.17%, respectively. In the morphology and rheology studies, P. citrinum showed a typical pellet morphology that was explained by a shaving mechanism; this phenomenon was significantly affected by carbon sources. The rheology of neo-FTase fermentation by P. citrinum was dependent on cell growth and fungal morphology.

Analysis of Finite Tandem Queues in Computer Communication Network (컴퓨터 통신망의 유한 길이 탄뎀 큐에 대한 해석)

  • 조진웅;이재호
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.12 no.6
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    • pp.545-553
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    • 1987
  • An approximation algorithm has been obtained to analyze the network of single server tandem queues with a finite length. In the queueing network with a finite queue length, the blocking which is mutually dependent, occure due to the limitation of the queue length. Thus, it is difficults to analyze such a queueing network. In this paper each queue has been regarded as the independent M/M/1/K system to analyze the queueing network with the blocking, which is based on the assumption that an arrival rate to the present station is increased by the blocking of the following stations. The performance measures, such as state probability, average queue length and tha waiting time, can be easily obtained using the proposed algorithm. In order to justify this approximation algorithm, comparison of the results of this algorithm with those of state transition simultaneous equations has been made an verified with computer simulation.

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A Study on East Fractal Image Decoder Using a Codebook Image (코드북 영상을 이용한 고속 프랙탈 영상 복호기에 관한 연구)

  • 이기욱;곽노윤
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.4 no.4
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    • pp.434-440
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    • 2003
  • Since Jacquine introduced the image coding algorithm using fractal theory, many fractal image compression algorithms providing good quality at low bit rate have been proposed by Fisher and Beaumount et al.. But a problem of the previous implementations is that the decoding rests on an iterative procedure whose complexity is image-dependent. This paper proposes an iterative-free fractal image decoding algorithm to reduce the decoding time. In the proposed method, under the encoder previously with the same codebook image as an initial image to be used at the decoder, the fractal coefficients are obtained through calculating the similarity between the codebook image and an input image to be encoded. As the decoding process can be completed with received fractal coefficients and predefined initial image without repeated iterations, the decoding time could be remarkably reduced.

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Electrochemical Polarization Characteristics and Effect of the CMP Performances of Tungsten and Titanium Film by H2O2 Oxidizer (H2O2 산화제가 W/Ti 박막의 전기화학적 분극특성 및 CMP 성능에 미치는 영향)

  • Na, Eun-Young;Seo, Yong-Jin;Lee, Woo-Sun
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.18 no.6
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    • pp.515-520
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    • 2005
  • CMP(chemical mechanical polishing) process has been attracted as an essential technology of multi-level interconnection. Also CMP process got into key process for global planarization in the chip manufacturing process. In this study, potentiodynamic polarization was carried out to investigate the influences of $H_2O_2$ concentration and metal oxide formation through the passivation on tungsten and titanium. Fortunately, the electrochemical behaviors of tungsten and titanium are similar, an one may expect. As an experimental result, electrochemical corrosion of the $5\;vol\%\;H_2O_2$ concentration of tungsten and titanium films was higher than the other concentrations. According to the analysis, the oxidation state and microstructure of surface layer were strongly influenced by different oxidizer concentration. Moreover, the oxidation kinetics and resulting chemical state of oxide layer played critical roles in determining the overall CMP performance. Therefore, we conclude that the CMP characteristics tungsten and titanium metal layer including surface roughness were strongly dependent on the amounts of hydrogen peroxide oxidizer.