• Journal of the Korean Society of Food Science and Nutrition
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• v.28 no.3
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• pp.691-697
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• 1999

The pharmacological effects of hydrocooked(110oC, 5 hours) extracts of Bastard halibut have been investigated. All of the hydrocooked extracts showed the measurable contractile effect on the isolated rat duodenum and decreased the normal blood pressure in anesthetized rat. The hydrocooked extracts also exhibited a dose dependent relaxation on the isolated rat aorta precontracted with phenylephrine. Only RM 60 fraction of these extracts had the cytotoxic effect against MCF7 cell(human breast adenocarcinoma cell line), but the other fractions showed neither antibacterial activity nor antitumor activity. Although fish extracts fed group of rat maintained their original body weight, there were no notable changes in the hematological parameters, except that the levels of high density lipoprotein was significantly increased. These results suggest that the hydrocooked extracts of bastard halibut may contain a variety of bioactive materials.

• Toxicological Research
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• v.12 no.2
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• pp.289-293
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• 1996

Our previous studies demonstrated that quinone (menadione) is cytotoxic to rat platelets. In an attempt to assess the relative contributions of redox cycling and/or arylation in quinone-induced cytotoxicity, we have studied three quinones with different mechanisms: 2, 3-dimethoxy-1, 4-naphthoquinone (DMNQ; pure redox cycler), menadione (both redox cycler and arylator), and 1, 4-benzoquinone (pure arylator). The order of redox cycling capacity in platelet rich plasma (PRP) isolated from rats was menadione>DMNQ>1, 4-benzoquonone, which was consistent with the previous studies using isolated hepatocytes. 1, 4-Benzoquinone was more toxic to rat platelets than menadione, while DMNQ did not cause cell death at all. Lactate dehydrogenase inhibition studies revealed that 1, 4-benzoquinone inhibited significantly in a time-dependent manner, while menadione and DMNQ did not at all. These results suggested that arylation by quinone compounds might play a critical role in quinone-induced cytotoxicity in rat platelets.

• Animal cells and systems
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• v.15 no.2
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• pp.155-159
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• 2011

Doublecortin (DCX) is microtubule-associated protein and is required for neuronal migration, differentiation and plasticity. In the retina, it is highly expressed between embryonic day 18 (E18) and E20, and is poorly expressed postnatally. In this study, we investigated the expression and cellular localization of DCX in the rat retina following ischemia induced by transiently increasing the intraocular pressure. While DCX immunoreactivity in control retinas was restricted to the outer border of the inner nuclear layer, it appeared in horizontal cell somata and processes in affected retinas. Quantitative evaluation by immunoblotting confirmed that DCX expression continuously increased after ischemia-reperfusion and showed 370% of control protein levels at 4 weeks after ischemic insult. These results suggest that the DCX in horizontal cells might play a role in neurite remodeling or modulating other neurons in ischemic rat retinas.

• Journal of Chest Surgery
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• v.51 no.6
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• pp.423-426
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• 2018

This study determined the feasibility of the cuff technique for small-caliber vascular grafts in a rat model. A graft was implanted with the cuff technique or suture technique in a 1-cm segment of the abdominal aorta in 12 rats. The mean aortic clamp time was 29 minutes with the cuff technique and 44 minutes with the suture technique; the cuff technique was significantly shorter. Abdominal angiography at 1 week after implantation showed no significant stenosis in 9 rats, focal stenosis of the mid-portion of the graft in 1 rat with each technique, and total occlusion of the graft in 1 rat with the suture technique. We have successfully used the cuff technique for anastomosis for small-caliber vascular grafts in an animal model.

• Annual Conference of KIPS
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• 2023.11a
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• pp.173-174
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• 2023

이 논문은 북한 해킹 그룹이 최근 유포하고 있는 악성코드 CHM 과 RokRAT 에 대해 연구하고 대응하는 목적으로 작성되었다. 악성코드 CHM 은 chm 파일 실행 시 도움말 창을 생성하여 내부 악성 스크립트가 동작하는 방식이다. 악성코드 RokRAT 은 윈도우에 기본 탑재된 lnk 파일을 pdf 아이콘으로 위장하여 사람들에게 유포하는 방식을 사용하였다. 이는 다양한 형식의 파일을 통해 유포되는 만큼 사용자가 보안 위협에 대한 경각심을 가지고 스스로 예방하고 대처할 수 있어야 한다는 결론을 내리고 있다.

• The Zoological Society Korea : Newsletter
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• v.12 no.2
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• pp.107.2-107
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• 1995

No Abstract, See Full Text

• 한국초전도학회:학술대회논문집
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• 2008.08a
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• pp.9-9
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• 2008

• Proceedings of the Korean Society of Embryo Transfer Conference
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• 2004.10a
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• pp.63-63
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• 2004

• Proceedings of the Zoological Society Korea Conference
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• 1995.10b
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• pp.243.2-243
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• 1995

No Abstract, See Full Text

• Journal of Korean Academy of Oral and Maxillofacial Radiology
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• v.20 no.1
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• pp.7-17
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• 1990