• 한국도로학회논문집
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• 제17권2호
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• pp.21-30
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• 2015

PURPOSES : The purpose of this study was to evaluate the performance of rapid-setting polymer-modified asphalt mixtures with a high reclaimed asphalt pavement (RAP) content. METHODS: A literature review revealed that emulsified asphalt is actively used for cold-recycled pavement. First, two types of rapid-setting polymer-modified asphalt emulsion were prepared for application to high-RAP material with no virgin material content. The quick-setting polymer-modified asphalt mixtures using two types of rapid-setting polymer-modified asphalt emulsion were subjected to the following tests: 1) Marshall stability test, 2) water immersion stability test and 3) indirect tensile strength ratio test. RESULTS AND CONCLUSIONS : Additional re-calibration of the RAP was needed for laboratory verification because the results of analyzing RAP aggregates, which were collected from different job sites, did not deviate from the normal range. The Marshall stability of each type of binder under dry conditions was good. However, the Type B mixtures with bio-additives performed better in the water immersion stability test. Moreover, the overall results of the indirect tensile strength test of RAP mixtures with Type B emulsions exceeded 0.7. Further research, consisting of lab testing and on-site application, will be performed to verify the possibility of using RAP for minimizing the closing of roadways.

• Advances in concrete construction
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• 제4권3호
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• pp.207-220
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• 2016

The objective of this study was to evaluate the influence of recycled materials, namely, shredded scrap tire (SST), reclaimed asphalt pavement (RAP) and class C fly ash (CFA) on compressive and tensile strength of concrete. Either SST or RAP was used as an aggregate replacement and class C fly ash (CFA) as Portland cement replacement for making concrete. A total of two types of SST and RAP, namely, chips and screenings were used for replacing coarse and fine aggregates, respectively. A total of 26 concrete mixes containing different replacement level of SST or RAP and CFA were designed. Using the mix designs, cylindrical specimens of concrete were prepared, cured in water tank, and tested for unconfined compressive strength (UCS) and indirect tensile strength (IDT) after 28 days. Experimental results showed aggregate substitution with SST decreased both UCS and IDT of concrete. On the contrary, replacement of aggregate with RAP improved UCS values. Specimens containing RAP chips resulted in concrete with higher IDT values as compared to corresponding specimens containing RAP screenings. Addition of 40% CFA was found to improve UCS values and degrade IDT values of SST containing specimens. Statistical analysis showed that IDT of SST and RAP can be estimated as approximately 13% and 12% of UCS, respectively.

• 한국도로학회논문집
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• 제19권1호
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• pp.37-44
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• 2017

PURPOSES : This study is primarily focused on evaluating the effects of the non-linear stress-strain behavior of RAP concrete on structural response characteristics as is applicable to concrete pavement. METHODS : A 3D FE model was developed by incorporating the actual stress-strain behavior of RAP concrete obtained via flexural strength testing as a material property model to evaluate the effects of the non-linear stress-strain behavior to failure on the maximum stresses in the concrete slab and potential performance prediction results. In addition, a typical linear elastic model was employed to analyze the structural responses for comparison purposes. The analytical results from the FE model incorporating the actual stress-strain behavior of RAP concrete were compared to the corresponding results from the linear elastic FE model. RESULTS : The results indicate that the linear elastic model tends to yield higher predicted maximum stresses in the concrete as compared to those obtained via the actual stress-strain model. Consequently, these higher predicted stresses lead to a difference in potential performance of the concrete pavement containing RAP. CONCLUSIONS : Analysis of the concrete pavement containing RAP demonstrated that an appropriate analytical model using the actual stress-strain characteristics should be employed to calculate the structural responses of RAP concrete pavement instead of simply assuming the concrete to be a linear elastic material.

• 한국지반환경공학회 논문집
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• 제10권5호
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• pp.19-26
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• 2009

짧은 쇄석다짐말뚝 공법(RAP)은 깊은 기초와 얕은 기초의 중간개념으로 1989년 미국에서 시작하여 세계적으로 활용성을 넓혀가고 있다. 국내의 경우, 체계적인 조사 및 연구가 이루어지지 않아 실제 현장에 적용하기 위한 설계시방이나 지지력 산정방법 등의 확보가 시급한 실정이다. 본 연구는 RAP공법의 구조물 기초로서의 배치형태에 따른 지지력 측정을 통해 사용성 확보를 위한 기초연구로써, 지지력 측면에서 최적의 배치에 대한 적용방안을 검증하기 위해서 이루어졌다. RAP공법이 적용된 지반의 지지력을 실내모형토조시험을 통하여 검토하였다. 연구방법은 사질토로 조성된 모형지반에 RAP의 배치형태별(정방형, 육각형, 십자형, 마름모형), 직경별(20mm, 30mm, 40mm)로 변위제어시험을 수행하여 RAP의 지지력을 검토하였다. 실험결과, 중심간 간격이 좁아짐에 따라 인접한 말뚝에 의한 구속효과 및 변형억제 등의 상호작용 효과가 증대되어 지지력이 증가하였으며, 직경이 커질수록 강성이 커져서 지지력이 증가하였다. 또한, 말뚝의 중심간격이 좁아짐에 따라 주변지반이 조밀해지면서 침하량도 감소하였다. 향후 다양한 현장계측자료의 축적을 통한 지속적인 검증작업과 침하량 및 지지력 측면에서 RAP의 최적 배치형태에 대한 연구가 요망된다.

• 한국도로학회논문집
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• 제20권1호
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• pp.69-76
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• 2018

PURPOSES : This study determined the optimal usage rate of RAP (reclaimed asphalt pavement) using cold central-plant recycling (CCPR) on a road-surface layer. In addition, a mixture-aggregate gradation design and a curing method based on the proposed rate for the surface-layer mix design were proposed. METHODS : First, current research trends were investigated by analyzing the optimum moisture content, mix design, and quality standards for surface layers in Korea and abroad. To analyze the aggregate characteristics of the RAP, its aggregate-size characteristics were analyzed through the combustion asphalt content test and the aggregate sieve analysis test. Moreover, aggregate-segregation experiments were performed to examine the possibility of RAP aggregate segregation from field compaction and vehicle traffic. After confirming the RAP quality standards, coarse aggregate and fine aggregate, aggregate-gradation design and quality tests were conducted for mixtures with 40% and 50% RAP usage. The optimum moisture content of the surface-layer mixture containing RAP was tested, as was the evapotranspiration effect on the surface-layer mixture of the optimum moisture content. RESULTS : After analyzing the RAP recycled aggregate size and extraction aggregate size, 13-8mm aggregate was found to be mostly 8mm aggregate after combustion. After using surface-chipping and mixing methods to examine the possibility of RAP aggregate segregation, it was found that the mixing method contributed very little for 3.32%, and because the surface-chipping method applied compaction energy directly as the maximum assumption the separation ratio was 15.46%. However, the composite aggregate gradation did not change. Using a 40% RAP aggregate rate on the surface-layer mixture for cold central-plant recycling satisfied the Abroad quality standard. The optimum moisture content of the surface-layer mixture was found to be 7.9% using the modified Marshall compaction test. It was found that the mixture was over 90% cured after curing at $60^{\circ}C$ for two days. CONCLUSIONS : To use the cold central-plant recycling mixture on a road-surface layer, a mixture-aggregate gradation design was proposed as the RAP recycled aggregate size without considering aggregate segregation, and the RAP optimal usage rate was 40%. In addition, the modified Marshall compaction test was used to determine the optimum moisture content as a mix-design parameter, and the curing method was adapted using the method recommended by Asphalt Recycling & Reclaiming Association (ARRA).

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제5권2호
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• pp.166-173
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• 2002

정도에서 흔히 볼 수 있는 증상으로, 정확한 원인을 발견할 수 없는 경우가 많다. 또한 반복성 복통이 학동기 아동에 있어 사회적, 정신적 발달에 장애를 초래할 수 있다. 이에 저자들은 반복성 복통과 정서적인 문제중 하나인 우울성향과의 연관성을 알아보고자 본 연구를 시행하였다. 방 법: 광주시내 2개 초등학교 4, 5, 6학년 학생 1,181명, 남아 566명, 여아 615명을 대상으로 반복성 복통의 유형을 평가하였으며, 우울의 정도는 한국판 Kovacs & Beck의 Children's Depression Inventory (CDI) 설문지를 이용하여 비교 분석하였다. 결 과: 1) 반복성 복통의 빈도는 총 265명(22.4%)이며 남아 107명(18.9%), 여아 158명(25.7%)으로 여아에서 의미 있게 높았고,연령별로 9세 19.8%, 10세 21.2%, 11세 26.1%, 12세 19.1%였다. 2) 반복성 복통군에서 평균 우울점수가 대조군에서 높았다. 3) 반복성 복통군에서 복통이 자주 있을수록, 다른 증상을 동반한 경우 우울점수가 유의하게 높았다. 4) 복통은 배꼽주위가 가장 많았고, 복통 양상이 쥐어 짜는 듯한, 화끈거리는 통증이 있는 경우에 우울점수가 의의 있게 높았다. 5) 반복성 복통군에서 아이의 성격이 혼자 놀기를 좋아하거나, 학교가기를 싫어하거나, 친구가 적은 경우의 우울점수가 성격이 활발하거나, 친구가 많거나, 꼼꼼한 경우보다 의미 있게 높았다. 6) 반복성 복통군에서 복통의 지속시간, 하루 중 복통의 발현시기 및 요일 사이에는 유의한 차이는 없었다. 결 론: 초등학교 아동에서 반복성 복통은 높은 유병율을 보이며, 우울점수가 대조군보다 높아 우울증과 연관성이 있음을 시사하였다 그러므로 학동기의 반복성 복통의 적절한 진단과 신속한 치료가 필요하며 치료시 정서적, 심리적 지지요법을 고려하는 것이 좋을 것으로 생각된다.

• BMB Reports
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• 제52권9호
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• pp.572-576
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• 2019

Bisphosphonates are the mainstay of therapy worldwide for osteoporosis. However, bisphosphonates also have limitations. The objective of this study was to determine the role of miR-101-3p/Rap1b signal pathway in osteoclast differentiation after treatment with bisphosphonates. Our results revealed that miR-101-3p was an important regulator in bisphosphonates treated-osteoclasts. When miR-101-3p was down-regulated in bone marrow-derived macrophage-like cells (BMMs), the development of mature osteoclasts was promoted, and vice versa. However, alendronate decreased multinucleated cell number regardless of whether miR-101-3p was knocked down or over-expressed. TRAP activity assay confirmed the above results. Luciferase assay indicated that miR-101-3p was a negative regulator of Rap1b. Western blot analysis revealed that protein expression level of Rap1b in BMMs transfected with OV-miR-101-3p was lower than that in BMMs transfected with an empty vector. Rap1b overexpression increased TRAP-positive multinucleated cells, while Rap1b inhibition decreased the cell numbers. In vivo data showed that miR-101-3p inhibited osteoclast differentiation in ovariectomized mice while overexpressed of Rap1b blocked the differentiation. Taken together, our data demonstrate that miR-101-3p/Rap1b signal pathway plays a key role in osteoclast differentiation after treatment with bisphosphonates.

• Journal of Microbiology and Biotechnology
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• 제11권2호
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• pp.337-341
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• 2001

To isolate antifungal substances from Korean radish (Raphanus Sativus L.) seeds, various purification techniques such as DE52 cellulose anion exchange, SP-Sephadex C-25 cation exchange, and Sephadex G-50 gel filtration chromatographies were used. The molecular masses of two purified R. sativus antifungal proteins (RAPs) were estimated to be about 6.1 kDa (RAP-1) and 6.2 kDa (RAP-2) by SDS-PAGE, and 5.8 kDa(RAP-1) and 6.2 kDa (RAP-2 by a gel filtration chromatography, respectively. Purified proteins RAP-1 and 2 clearly exhibited different growth inhibitory activities against other microorganisms like Candida albicans and Saccharomyces cerevisiae. Although they have similar molecular masses, both RAP-1 and 2 proteins are not identical because their microbial inhibitory actions were different. Therefore, RAP-1 could be a new antifungal protein when compared with the antifungal activities of 2S albumins, Rs-AFPs, Mj-AMPs, chitinase, glucanase, permatin, and ribosome inactivating proteins, all of which are anifungal proteins of plants.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2005년도 춘계 학술발표회 논문집
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• pp.1108-1117
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• 2005

RAP(rammed aggregate pier) method which is intermediate foundation of deep and shallow foundation is used to improve the ground with high compaction energy. This method is widely spread around the world, but there are few examples and systemic researches for failure mechanism and bearing capacity of this method are not organized yet. In this paper, soil laboratory tests were carried out to evaluate the applicability of RAP method as the foundation of a structure. And the bearing capacity and the failure mechanism of RAP method were studied with respect to various relative densities(35%, 65%, 90%), diameters(45mm, 60mm) and lengths(20cm, 30cm, 40cm). As results, stress concentration ratio decreased as diameter of RAP was increasing or length of RAP was decreased or relative density was decreased. however these results were not always constant. because systematic interaction between relative density and diameter and length of RAP can affect stress concentration ratio, more studies on stress concentration ratio are needed throughout laboratory and field tests.

• 한국도로학회논문집
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• 제19권2호
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• pp.55-65
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• 2017

PURPOSES : This study aimed to analyze the experimental and numerical behavior of warm mix asphalt pavement prepared using steel slag and RAP and to conduct economic analysis of pavement construction. METHODS : For developing high performance asphalt pavement, we performed three evaluations: fundamental analysis, experimental testing, and 3D finite element analysis. In particular, 3D finite element analysis was conducted on several pavement structures by adopting the results of experimental tests. RESULTS : Through the various evaluations, it was established that steel slag was effective for use as asphalt mixture aggregate. Moreover, asphalt mixture constituting steel slag and RAP demonstrated higher performance behavior compared with conventionally used asphalt mixture. Furthermore, based on the 3D FE modeling, we established that the developed asphalt pavement constituting steel slag and RAP can be utilized for thin layer pavement with comparable performance behavior. CONCLUSIONS :Warm mix asphalt pavement prepared using steel slag and RAP is more competitive and economic compared to hot-mix asphalt pavement. Moreover, it can be applied for preparing thin layer asphalt pavements with reasonable performance. The developed warm mix asphalt pavement prepared using steel slag and RAP can be an alternative pavement type with competitive performance based on the reasonable economic benefit it provides.