• Maxillofacial Plastic and Reconstructive Surgery
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• 제37권
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• pp.7.1-7.7
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• 2015

Background: Osteoradionecrosis is a delayed complication from radiation therapy which causes chronic pain, infection and constant deformity after necrosis. Most of the osteoradionecrosis occurs spontaneously or after the primary oncologic surgery, dental extraction or by trauma of prosthesis. The treatment of osteoradionecrosis relies on both conservative measures and surgical measures. The fibular osteocutaneous free flap has become more popular choice for reconstruction of maxillofacial defects as a treatment of osteoradionecrosis. Methods: We presented our experiences from 7 patients with osteoradionecrosis who have had reconstruction surgery with fibular osteocutaneous free flap at National Cancer Center during the recent 5 years. We performed segmental mandibular resection with fibular osteocutaneous free flap for all 7 patients of advanced osteoradionecrosis who were not controlled by conservative treatment such as wound irrigation, debridement, and antibiotics. Results: A wide range of techniques were available for the reconstruction of composite defects resulted from the treatment of advanced mandibular osteoradionecrosis. Significant improvement was noted in relieving pain and treating trismus after the surgery however difficulty in swallowing and xerostomia showed less improvement. Conclusions: We concluded that fibular osteocutaneous free flap can be performed safely in patients with osteoradionecrosis and yields positive outcomes with significantly increased success rate. The fibular osteocutaneous free flap was our preferred choice for the mandibular reconstruction due to its versatility and predictability.

• Korean Chemical Engineering Research
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• 제55권5호
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• pp.668-678
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• 2017

Intermolecular interactions were studied for binary mixtures of 2-propanol + cyclohexane, n-hexane, benzene, toluene, o-, m- and p-xylenes by measuring ultrasonic speeds (u) over the entire range of composition at 298.15 K and 308.15 K. From these results the deviation in ultrasonic speed was calculated. These results were fitted to the Redlich-Kister equation to derive the binary coefficients along with standard deviations between the experimental and calculated data. Acoustic parameters such as excess isentropic compressibility ($K_s^E$), intermolecular free length ($L_f$) and available volume ($V_a$) were also derived from ultrasonic speed data and Jacobson's free length theory. The ultrasonic speed data were correlated by Nomoto's relation, Van Dael's mixing relation, impedance dependence relation, and Schaaff's collision factor theory. Van Dael's relation gives the best prediction of u in the binary mixtures containing aliphatic hydrocarbons. The ultrasonic speed data and isentropic compressibility were further analyzed in terms of Jacobson's free length theory.

• 대한한방소아과학회지
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• 제28권1호
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• pp.1-6
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• 2014

Objectives This study aimed to evaluate the effects of atopic care program through observing atopic patients who have lived in atopic-free village located Geumsan of Chungnam province. Methods Seventeen children (boy 7, and girl 10) with atopic dermatitis had moved into atopic-free village of Geumsan, and they have been cared with atopic care program. Atopic dermatitis symptoms were measured every month using SCORAD (Scoring of Atopic Dermatitis) and EASI (Eczema Area and Severity Index) from March, 2012 to September, 2013. The changes of scores were analyzed using paired t-test. Results The median month of residence period was 19.9 months (range from 6 to 42 months). The atopic symptoms were significantly improved on SCORAD (p<0.01) and EASI (p<0.1) respectively. Conclusion Despite the limitation of the small number of study subjects, this study may provide the possibility of natural environment-based therapy for children with atopic dermatitis.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2005년도 춘계학술대회논문집
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• pp.832-835
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• 2005

본 연구는 지반에 근입된 변단면 말뚝의 자유진동에 관한 연구이다. 이 논문에서는 말뚝이 근입된 지반을 Winkler형으로 이상화하여 변단면 말뚝의 자유진동을 지배하는 상미분방정식을 무차원형으로 표현하였으며, 이를 수치해석하여 대상구조의 고유진동수를 산출하였다. 수치해석 예에서는 상단이 자유, 하단이 회전지점과 회전스프링으로 이루어진 말뚝을 대상으로 회전스프링상수, 근입비, 지반계수, 접촉면의 폭비에 따른 고유진동수를 산출하고 그 결과를 고찰하였다.

• 한국미생물·생명공학회지
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• 제23권3호
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• pp.304-310
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• 1995

A thermophilic bacterium producing the extracellular cellulase-free xylanase was isolated from soil and has been identified as Bacillus sp. The optimal growth temperature was 50$\circ$C and the optimal pH, 7.0. Under the optimal growth condition, maximal xylanase production was 2.2 units/ml in the flask culture. The enzyme production was induced by xylan and xylose, but was repressed by sucrose or trehalose. The partially purified xylanase was most active at 70$\circ$C. It was found that the enzyme was stable at 65$\circ$C for 10 hours with over 75% of the activity. The enzyme was most active at pH 7.0 and retained 90% of its maximum activity between pH 5.0 and pH 9.0 though Bacillus sp. was not grown on alkaline conditions (>pH 8.0). In addition, the activity of xylanase was over 60% at pH 10.0. At the ambient temperature, the enzyme was stable over a pH range of 5.0 to 9.0 for 10 h, indicating that the enzyme is thermostable and alkalotolerant. The activity of xylanase was completely inhibited by metal ions including Hg$^{2+}$ and Fe$^{2+}$, while EDTA, phenylmethylsulfonyl fluoride (PMSF), $\beta$-mercaptoethanol and SDS didn't affect its activity. The enzyme was also identified to exert no activity on carboxymethylcellulose, laminarin, galactomannan, and soluble starch.

• 대한기계학회논문집B
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• 제20권2호
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• pp.697-709
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• 1996

Supersonic axisymmetric jets issuing from various kinds of nozzles with a throat diameter of a few millimeters were experimentally investigated. The exit Mach number and Reynolds number based on the throat diameter of nozzle were in the range of 1.0 ~ 5.9 and 8.4$\times$ $10^4$ ~ 2.9$\times$$10^6$, respectively. The nozzle pressure ratio was varied from 5 to 85. Present paper aims to offer fundamental information of the supersonic free-jets, with an emphasis to give data with which the shape of the free-jets can be depicted under a specified condition. Experimental data are summarized to enable an estimation of the shape of the supersonic free-jets. The result shows that the shape of free-jets is dependent on only the nozzle pressure ratio.

• 한국대기환경학회지
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• 제27권6호
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• pp.681-691
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• 2011

The size distributions of smoke particles from fire are prerequisite for the studies on fire detection and adverse health effects. Above the flame of the fire, coagulation dominates and the smoke particles grow from 1 to 50 nm up to 100 to 3,000 nm, sizes ranging from the free-molecular regime to the continuum regime. The characteristics of the agglomeration of the smoke particles are well known, independently for each of the free-molecular and continuum regimes. However, there are not many systematic studies in the entire regime by the complexity of the mechanisms. The purpose of this work is to find the characteristics of the development of the size distribution of smoke particles by agglomeration in the entire size range covering the free-molecular regime, via transition regime, to the near-continuum and continuum regime for each variation of parameters such as fractal dimension, primary particle size and dimensionless coagulation time. In this work, the dynamic equation for the discrete-size spectrum of the particles was solved using a nodal method based on the modification of a sectional method. In the calculation, the collision frequency function for the entire regime, which is derived by using the concept of collision volume and general enhancement function, was applied. The self-preserving size distribution for the entire regime is compared with the ones for the free-molecular or continuum regimes for each variation of the parameters.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1994년도 하계학술대회 논문집 C
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• pp.1416-1418
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• 1994

Expressions for the displacement of a bimorph, one end fixed and the other free, has been introduced when sinusoidal inputs were applied to the ceramic plates on a thin metal plate. Maximum displacements at the free end and strains at the position of strain gage attached were measured when various wave forms, voltages, and frequencies were applied to the bimorph whose length is 6.6[cm], width 2.5[cm], and thickness 0.0365[cm]. Under the constant voltage ( $70[V_{peak}]$ ), the strains and the displacements at the free end were larger than the case of the sinusoidal input when the square wave was applied and were smaller when triangular wave. It was shown that the displacements at the free end and the strains of the gage position were increased as the applied voltage in the range of $30-90[V_{peak}]$ and effective length were increased. And it was also found that the resonant frequency of a bimorph was decreased as its effective length was increased, and that the displacements and the strains were maximum at the resonant frequency.

• 지구물리와물리탐사
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• 제3권2호
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• pp.61-69
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• 2000

지표 경계 조건은 유한 차분법을 이용한 탄성파 파동 방정식 모델링에서 수치해의 정확성을 떨어뜨리는 한편 포아송 비에 따른 해의 안정성을 제한하는 주 요인이 된다. 본 연구에서는 지표 경계 조건과 같은 Neumann 경계 조건의 처리에 효과적인 적분법(integration method)에 기반 하여 차분식을 유도하고, 이로부터 중간점 차분 기법을 제안하였다. 또한, 개발된 알고리즘을 Lamb의 문제에 적용하여 이론해와 비교함으로써 타당성을 검증하였다.

• 대한조선학회지
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• 제23권2호
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• pp.1-13
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• 1986

The nonlinear hydrodynamic forces acting on a two-dimensional circular cylinder, oscillating with large amplitude in the free surface, are calculated by using the Semi-Lagrangian Time-Step-ping Method used by O.M. Faltinsen. In present calculation the position and the potential value of free surface are calculated using the exact kinematic and dynamic free surface boundary condition. At each time step an integral equation is solved to obtain the value of potential and normal velocity along the boundaries, consisting of both the body surface and the free surface. Some effort was devoted to the elimination of instability arising in the range of high frequency. Numerical simulations were performed up to the 3rd or 4th period which seems to be enough for the transient effect to die out. Each harmonic component and time-mean force are obtained by the Fourier transform of forces in time domain. The results are compared with others' experimental and theoretical results. Particularly, the calculation shows the tendency that the acceleration-phase 1st-harmonic component(added mass) increases as the motion amplitude increases and a reverse tendency in the velocity-phase 1st-harmonic component(damping coefficient). The Yamashita's experimental result also shows the same tendency. In general, the present result show relatively good agreement with the Yamashita's experimental result except for the time-mean force.