• Title/Summary/Keyword: randomized clinical controlled trial

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Chuna Manual Therapy for Rheumatoid Arthritis : A Systematic Review and Meta-analysis (류마티스 관절염에 대한 추나요법의 효과 : 체계적 문헌고찰과 메타분석)

  • Heo, In;Han, In-Sik;Cha, Yun-Yeop
    • The Journal of Churna Manual Medicine for Spine and Nerves
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    • v.13 no.1
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    • pp.1-10
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    • 2018
  • Objectives: To evaluate the evidence supporting the effectiveness of Chuna manual therapy for rheumatoid arthritis. Methods: We conducted a search across 9 electronic databases to find all randomized controlled clinical trials (RCTs) that used Chuna manual therapy as a treatment for rheumatoid arthritis. The methodological quality of each RCT was assessed using the Cochrane risk of bias tool. Results: Our inclusion criteria were met by 5 RCTs. The meta-analysis showed positive results for the use of Chuna manual therapy combined with oriental usual care (UC) in terms of the efficacy rate, pain, and duration of morning stiffness when compared to western UC. Positive results were also obtained in terms of the efficacy rate, when Chuna manual therapy combined with medication was compared to medication treatments alone. Conclusions: Our systematic review found encouraging, but limited evidence of Chuna manual therapy for rheumatoid arthritis. However, to obtain stronger evidence without the drawbacks of trial design and the quality of studies, we recommend a comparative research to test the effectiveness of Chuna manual therapy.

Effects of San-Yin-Jiao (SP6) Acupressure on Anxiety, Pulse and Neonatal Status in Women during Labor (삼음교(SP6) 지압이 산부의 불안, 맥박 및 신생아 상태에 미치는 효과)

  • Lee, Mi-Kyeong
    • Women's Health Nursing
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    • v.9 no.2
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    • pp.138-151
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    • 2003
  • Purpose: In the study effects of San-Yin-Jiao (SP6) acupressure on anxiety and pulse during labor, and on neonatal status were examined. Method: The design was a randomized controlled clinical trial with a double-blind method. Data were collected before (pre) and after (post) treatment using structured questionnaire, anxiety scale, pulse rate, umbilical vein pH and Apgar scores. The experimental group received SP6 acupressure for the duration of each uterine contraction over a period of 30 minutes, but the control group received SP6 touch. Results: The anxiety scores between the two groups increased, but the increase was less in the SP6 acupressure group and the difference was statistically significant (p=0.019). Maternal pulse rate was not significantly different immediately after treatment (p=0.711), at 30 and at 60 minutes (p=0.140 ; p=0.108), but while the SP6 acupressure group had a stable pulse, the SP6 touch group showed an increased rate. There was no significant difference between the two groups for umbilical vein pH (p=0.124), and neonatal Apgar score at one and five minutes (p=0.387 ; p=0.979). Conclusion: These findings strengthen the belief that SP-6 acupressure can be used to relieve anxiety during labor with no side effects to either mother or baby.

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Study of the Efficacy and Safety of "adenophorae radix extract" in the Obese Patients or Overweight (비만 및 과체중 환자에 대한 사삼추출물의 유효성 및 안전성 평가)

  • Kim, Gi-Tae;Go, Heung;Shin, Seon-Mi;Kim, Hyung-Jun
    • The Journal of Korean Obstetrics and Gynecology
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    • v.25 no.2
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    • pp.131-141
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    • 2012
  • Objectives: The purpose of this study is to evaluate the efficacy and biosafety of Adenophorae Radix(AR) extract in obesity or overweight patient. Methods: This study is double-blind, randomized, placebo-controlled intervention Study. 30 patients with BMI $25{\leq}$ and 30> were allotted into two groups at random. In 0, $6^{th}$, $12^{th}$ week, we had checked body weight, waist line, hip line, body fat and abdominal CT scan. In 0, $12^{th}$ week, we also had checked lipid metabolism and biosafety with blood test. Results: AR treatment had a significant effect on suppressing body wight gain (p<0.01) and BMI index(p<0.01). AR treatment reduced plasma TG level but we couldn't find statistical significance. AR treatment had produced no adverse reactions. Conclusions: This study shows that Adenophorae Radix(AR) extract can reduce the weight, BMI. Adenophorae Radix(AR) extract can be used in obesity or overweight patient.

Mental Exercises for Cognitive Function: Clinical Evidence

  • Kawashima, Ryuta
    • Journal of Preventive Medicine and Public Health
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    • v.46 no.sup1
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    • pp.22-27
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    • 2013
  • The purpose of this study was to examine the beneficial effects of a new cognitive intervention program designed for the care and prevention of dementia, namely Learning Therapy. The training program used systematized basic problems in arithmetic and Japanese language as training tasks. In study 1, 16 individuals in the experimental group and 16 in the control group were recruited from a nursing home. In both groups, all individuals were clinically diagnosed with senile dementia of the Alzheimer type. In study 2, we performed a single-blind, randomized controlled trial in our cognitive intervention program of 124 community-dwelling seniors. In both studies, the daily training program using reading and arithmetic tasks was carried out approximately 5 days a week, for 15 to 20 minutes a day in the intervention groups. Neuropsychological measures were determined simultaneously in the groups both prior to and after six months of the intervention. The results of our investigations indicate that our cognitive intervention using reading and arithmetic problems demonstrated a transfer effect and they provide convincing evidence that cognitive training maintains and improves the cognitive functions of dementia patients and healthy seniors.

A Review on Korean Traditional Medicine Research against Human Papillomavirus Infection and Cervical Dysplasia - Focused on Randomized Controlled Trial of Human Papillomavirus Infection and Cervical Dysplasia - (인유두종 바이러스 감염과 자궁경부 이형성증과 관련된 한방 임상연구 동향 - 무작위 대조 비교 임상시험을 중심으로 -)

  • Chung, Jae-Ryung;Hwang, Deok-Sang;Lee, Jin-Moo;Jang, Jun-Bock;Lee, Chang-Hoon
    • The Journal of Korean Obstetrics and Gynecology
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    • v.32 no.4
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    • pp.55-66
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    • 2019
  • Objectives: This review is to figure out evidence that suggests the effectiveness of Korean Medicine treatments against Human Papilloma virus (HPV) infection and Cervical Dysplasia. Methods: Studies on HPV infection and cervical dysplasia were searched through 5 databases: Oriental Medicine Advanced Searching Integrated System (OASIS), Korean Studies Information Service System (KISS), the Journal of Korean Obstetrics & Gynecology, China Academic Journal (CAJ), Pubmed. After that, the articles were extracted with reference point of Korean Traditional Medicine. Results: 21 studies were included lastly according to selection criteria. In 21 studies, HPV turning - negative rate of Korean Medicine treatment group was higher than the control treatment group. Conclusions: 21 studies indicates that Korean Medicine treatment is effective in HPV infection and Cervical Dysplasia.

Effects of Static and Dynamic Stretching on Lumbar Lordotic Angle and Low Back Pain in University Students

  • Ga, Heayoung;Gim, Mina
    • Journal of International Academy of Physical Therapy Research
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    • v.10 no.3
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    • pp.1834-1839
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    • 2019
  • Background: Lumbar lordosis is a result of muscle shortening and may cause low back pain. Objective: To examine the effects of static and dynamic stretching on lumbar lordosis and low back pain in university students. Stretching is an intervention that can be applied to shortened muscles; however, very few studies have compared the effects of static and dynamic stretching on lumbar lordosis and low back pain. Design: Randomized controlled clinical trial (single-blind) Methods: The 12 selected subjects were randomly assigned static stretching and dynamic stretching groups each containing six students. The subjects in each group performed their respective stretching programs for 17 minutes, 3 times a week for 4 weeks. Lumbar lordotic angle, low back pain, and Oswestry Disability Index (ODI) were measured before and after the intervention. Results: Intragroup comparisons showed significant reductions in lumbar lordotic angle and low back pain in the static stretching group while the dynamic stretching group showed significant decreases in lumbar lordotic angle, low back pain, and ODI. The intergroup comparisons showed significantly greater differences between pre- and post-intervention in lumbar lordotic angle and low back pain in the dynamic stretching group compared to those in the static stretching group while ODI did not show any intergroup difference. Conclusions: The results of this study indicated that, while both static and dynamic stretching helped to reduce the lumbar lordotic angle and low back pain, dynamic stretching was more effective in alleviating lumbar lordotic angle and low back pain compared to static stretching.

The Effects of Vibration Exercise after Modified Bröstrom Operation in Soccer Players with Ankle Instability

  • Kim, Sanghoon;Kim, Yangrae;Kim, Yongyoun
    • Journal of International Academy of Physical Therapy Research
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    • v.10 no.2
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    • pp.1791-1796
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    • 2019
  • Background: Vibration exercise after ankle surgery improves proprioception and ankle muscle strength through vibration stimulation. Objective: To examine the effects of vibration exercise on the ankle stability. Design: Randomized controlled clinical trial (single blind) Methods: Twenty soccer players were randomly divided into experimental group and control group. The Vibration exercise program was conducted 12 weeks and 3 times a week. Ankle joint proprioceptive sensory test and Isokinetic muscle strength test were performed using Biodex system pro III to measure plantar flexion / dorsiflexion and eversion / inversion motion. Results: The result of isokinetic test of ankle joint is showed significant improvement in all measurement items, such as leg flexion, lateral flexion, external and internal muscle forces, compared to previous ones by performing vibration movements for 12 weeks. However, in the comparison group, plantar flexor ($30^{\circ}$), eversion muscle ($120^{\circ}$), inversion ($30^{\circ}$) of limb muscle strength were significantly improved compared with the previous phase; was no significant difference in dorsi-flexion. There was no significant difference between groups in all the items. Conclusions: In this study, we analyzed the effects of rehabilitation exercise on soccer players who had reconstructed with an ankle joint ligament injury through vibration exercise device. As a result, we could propose an effective exercise method to improve the ability, and confirmed the applicability as an appropriate exercise program to prevent ankle injuries and help quick return.

The Effect of Arm Movements in the during Standing Position on Lower Limb Global Synkinesis and Balance in Stroke Patients

  • Moon, YoungJun;Jeong, DaeKeun;Kang, Jeongil
    • Journal of International Academy of Physical Therapy Research
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    • v.10 no.3
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    • pp.1849-1855
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    • 2019
  • Background: Stroke patients require arm movement exercising for various stimulations in standing position for various stimulations rather than in a sitting position because they require integrated skillful movements, such as stretching, holding, and controlling. Objective: This study was conducted to provide foundational clinical data about lower limb global synkinesis in stroke patients using arm movements in a standing position. Design: Randomized controlled trial. Methods: The subjects were divided into a control group (n = 10) and an experimental group (n = 10), and a pre-test was conducted to evaluate leg global synkinesis (GS) and balance. Intervention method is stretching an arm to hold a ball, repeating supination and pronation of the hand only while maintaining the arm extended as much as possible, repeating shoulder abduction and adduction while holding the pegboard. This was followed by a three-week intervention during which re-measurement was conducted in the same way as was done for the pre-test. Results: The control group showed a significant difference in GS and balance during plantar flexion (p<.05), and the experimental group showed a significant difference in GS and balance during all movements (p<.05, p<.01, respectively). There was a significant difference in GS and balance between the two groups during dorsiflexion (p<.05, p<.01, respectively). Conclusion: The findings demonstrate that human arm movements in a standing position can reduce GS in the affected limb, and balance can be improved by stimulating the surrounding tissues of the affected limb and changing them positively.

The Latest Trends of Treatment for Acne Vulgaris in PubMed (PubMed를 통해 살펴 본 최신 여드름 치료 연구 경향 최근 3년 간 북미, 유럽 논문을 중심으로)

  • Lee, Woo-Gun;Kim, Bong-Hyun;Jeon, Sun-Woo;Kim, Kyu-Seok;Nam, Hae-Jeong;Kim, Yoon-Bum
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.24 no.2
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    • pp.41-56
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    • 2011
  • Objective : The purpose of this study is to study trends in Western(North America and Europe) medical treatments for the acne vulgaris. This study analyzed research on acne vulgaris in PubMed. Methods : We searched PubMed related the latest medical treatments for acne vulgaris. We analyzed 21 research papers and examined published journals, years, countries, and their methods, results, interventions, participants, periods and instruments of assessment. Results : The method of studies was mostly double-blind, randomized controlled trial. There were research papers concerning treatment with light-lazer, topical agents, and oral contraceptives. There were more positive results compared to negative results for efficacy of treatment. The median for number of participants was 364.0 persons. The median for periods was 67.8 days. Assessment for outcomes were lesion counts, adverse effects, VAS, etc. Conclusions : It is necessary to study latest trends of Western medical treatments for acne vulgaris and understand strengths and weaknesses of those. It will be helpful to more in-depth develop clinical treatments of Oriental Medicine for acne vulgaris.

Evaluating the effects of probiotics in pediatrics with recurrent abdominal pain

  • Rahmani, Parisa;Ghouran-Orimi, Azin;Motamed, Farzaneh;Moradzadeh, Alireza
    • Clinical and Experimental Pediatrics
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    • v.63 no.12
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    • pp.485-490
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    • 2020
  • Background: Recurrent abdominal pain (RAP) is one of the frequent complaints in general practice, particularly in pediatrics and is among the common cause of referral to gastroenterology clinics. Purpose: This study is designed to investigate the effects of probiotics for the treatment of RAP and desired therapeutic outcomes. Methods: One hundred twenty-five children with the diagnosis of RAP according to Rome III criteria for irritable bowel syndrome (IBS), functional abdominal pain (FAP), functional dyspepsia (FD), and abdominal migraine (AM), were enrolled in this double-blind randomized controlled trial. Results: Sixty-five subjects received probiotics, and others received placebo treatment for 4 weeks. Lactobacillus reuteri was therapeutically effective in 32 patients compared to 8 patients, responding to the placebo treatment. Compared to baseline, all pain-related variables showed a significant reduction for the IBS and FD at the end of the 4th week. However, it did not respond well in FAP and AM groups. Pain-related outcomes such as, frequency of the pain, severity, and duration of the pain were decreased following the probiotic treatment. No therapeutic response was seen in AM group after the administration of probiotics. L. reuteri significantly led to pain relief in the overall population, and also in FAP, FD, and IBS subgroups. Conclusion: L. reuteri probiotics are likely to lead to RAP relief and can be recommended for the treatment of functional gastrointestinal disorders.