• Title/Summary/Keyword: randomization

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Inference for heterogeneity of treatment eect in multi-center clinical trial

  • Ha, Il-Do
    • Journal of the Korean Data and Information Science Society
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    • v.22 no.3
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    • pp.605-612
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    • 2011
  • In multi-center randomized clinical trial the treatment eect may be changed over centers. It is thus important to investigate the heterogeneity in treatment eect between centers. For this, uncorrelated random-eect models assuming independence between random-eect terms have been often used, which may be a strong assumption. In this paper we propose a correlated frailty modelling approach of investigating such heterogeneity using the hierarchical-likelihood method when the outcome is time-to-event. In particular, we show how to construct a proper prediction interval for frailty, which explores graphically the potential heterogeneity for a treatment-by-center interaction term. The proposed method is illustrated via numerical studies based on data from the design of a multi-center clinical trial.

Species Associations with Spatial Autocorrelation Analysis of Pinus rigida and Pyrola japonica

  • Huh, Man-Kyu;Huh, Hong-Wook;Kim, Chang-Ho
    • The Korean Journal of Ecology
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    • v.22 no.6
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    • pp.349-354
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    • 1999
  • The spatial distributions of allelic frequencies and ecological traits by randomization were studied in the natural population of two species (Pinus rigida and Pyrola japonica). Both species showed significant positive spatial autocorrelation as measured by Moran's I. In P. rigida, the genetic similarity was shown in individuals within up to a scale of 18 m distance and this is partly due to combination of pollen and seed dispersal by wind or men. In P. japonica, significant spatial autocorrelation was consisted of a scale of 8 m intervals. These population structure in the distribution of allelic frequencies is related to mating systems such as outcrossing and vegetative spread. The results also indicate that positive species associations between P. rigida and P. japonica can occur when both species select the same habitat or require the same environmental conditions.

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The Reduction of Tire Pattern Noise Using Time-Frequency Transform (저소음 타이어 설계에 대한 시변주파수 분석 적용)

  • Hwang, S.W.;Bang, M.J.;Kim, S.J.;Cho, C.T.
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2005.11b
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    • pp.144-147
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    • 2005
  • The tire is considered as one of the Important noise sources having an influence on vehicle's performance. The Pattern noise of a tire is the transmission sound of airborne noise. On smooth asphalt road, Pattern noise is amplified with the velocity. In recent, the study on the reduction of Pattern noise is energetically processed. Pattern noise is strongly related with pitch sequence. To reduce the pattern noise, tire's designer has to randomize the sequence of pitch. The FFT is a traditional method to evaluate the level of the randomization of the pitch sequence, but gives no information on time-varying, instantaneous frequency. In the study, we found that Time-Frequency transform is a useful method to non-stationary signal such as tire noise.

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Prediction of retention of uncharged solutes in nanofiltration by means of molecular descriptors

  • Nowaczyk, Alicja;Nowaczyk, Jacek;Koter, Stanislaw
    • Membrane and Water Treatment
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    • v.1 no.3
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    • pp.181-192
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    • 2010
  • A linear quantitative structure-property relationship (QSPR) model is presented for the prediction of rejection in permeation through membrane. The model was produced by using the multiple linear regression (MLR) technique on the database consisting of retention data of 25 pesticides in 4 different membrane separation experiments. Among the 3224 different physicochemical, topological and structural descriptors that were considered as inputs to the model only 50 were selected using several criteria of elimination. The physical meaning of chosen descriptor is discussed in detail. The accuracy of the proposed MLR models is illustrated using the following evaluation techniques: leave-one-out cross validation procedure, leave-many-out cross validation procedure and Y-randomization.

Deformation and Recrystallization of INCONEL 690 (인코넬 690의 변형 및 재결정)

  • 표은종;허무영
    • Proceedings of the Korean Society for Technology of Plasticity Conference
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    • 1995.10a
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    • pp.167-171
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    • 1995
  • The formation of preferred orientations in cold rolled and recrystallized Inconel 690 sheets was studied by the x-ray texture measurements and TEM observations. The increasing{220} pole intensity in the plane normal at the higher reductions was related to the{110}<112> texture component. The rolling texture of the Inconel 690 was the pure metal type. THe dislocation cells were found in the near{110}<112> oriented grains. The onset of deformation twins in the {112}<111>oriented grains. The onset of deformation twins in the {112}<111> oriented grains. The onset of deformation twins in the {112}<111> oriented grains caused the weakening of {112}<111> and the development of {552}<115> in the rolling texture. The annealing texture of the Inconel 690 sheets was dependent on the annealing temperature. The annealing texture of 750$^{\circ}C$ annealed sheets was similar to the cold rolling texture. The major preferred orientations of the 950$^{\circ}C$ annealed specimens were {112}<110> and {001}<110>. The formation of fine and closely spaced annealing twins in the specimen annealed at 1150$^{\circ}C$ led to the randomization of the annealing texture.

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Random Forest Model for Silicon-to-SPICE Gap and FinFET Design Attribute Identification

  • Won, Hyosig;Shimazu, Katsuhiro
    • IEIE Transactions on Smart Processing and Computing
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    • v.5 no.5
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    • pp.358-365
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    • 2016
  • We propose a novel application of random forest, a machine learning-based general classification algorithm, to analyze the influence of design attributes on the silicon-to-SPICE (S2S) gap. To improve modeling accuracy, we introduce magnification of learning data as well as randomization for the counting of design attributes to be used for each tree in the forest. From the automatically generated decision trees, we can extract the so-called importance and impact indices, which identify the most significant design attributes determining the S2S gap. We apply the proposed method to actual silicon data, and observe that the identified design attributes show a clear trend in the S2S gap. We finally unveil 10nm key fin-shaped field effect transistor (FinFET) structures that result in a large S2S gap using the measurement data from 10nm test vehicles specialized for model-hardware correlation.

Investigation of present hygienic condition of rural area drinking water in Kunming 2004

  • Zhang, Liang;Wang, Xin;Liu, Xinhai
    • Proceedings of the Korean Environmental Health Society Conference
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    • 2004.12a
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    • pp.8-11
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    • 2004
  • Objective To know about hygienic condition of drinking water in rural area of Kunming. Methods Selected 4 counties with different economy to investigate. In every county, according to the proportion, 10 drinking water spots were selected by randomization of lift drinking water'. Results In 4 areas, surface water for drinking is 82.41%, under water is 17.59%. And concentrated supply is 83.02% by populated proportion, others are 16.98%. 40 specimens qualification rate is 47.50%, and in it concentrated supply is 87.50%, others are 19.05%. Conclusion Unhealthy drinking water exist in most testing counties. Mainly microorganism isn't qualified. Concentrated management in drinking water is batter than other ways.

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Randomized Clinical Trials of Herbal Acupuncture for Placebo Control (플라세보 약침에 대한 무작위배정 임상시험)

  • Seo, Jung-Chul;Xue, Charlie
    • Journal of Acupuncture Research
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    • v.25 no.6
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    • pp.153-161
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    • 2008
  • Objectives : This study was designed to find out whether normal saline(NS) acupuncture is able to be constituted as an appropriate control group for Cervi Cornu Parvum herbal acupuncture(CC). Methods : NS and CC were injected into Quchi($LI_{11}$) of the subjects. The subjects completed a questionnaire rating the intensity of 21 kinds of acupuncture sensation(hurting, penetrating, sharp, aching, intense, spreading, radiating, tingling, pricking, stinging, pulling, heavy, dull, numb, electric, shocking, hot, burning, cool, pulsing, and throbbing) and side effects. We compared subjective evaluations of acupuncture sensation and side effects between two groups. Results : As for CC most of the acupuncture sensation items were not significantly different from NS especially in less acupuncture-experienced subjects(average 2, below 10 time experiences) rather than more acupuncture-experienced subjects(above 10 time experiences). Conclusions : We found that NS might be an appropriate placebo herbal acupuncture for CC in small amount of acupuncture-experienced subjects. Further study is needed for new placebo herbal acupuncture for CC in more acupuncture-experienced subjects.

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REDUCTION OF AUDIBLE SWITCHING NOISE IN INDUCTION MOTOR DRIVES USING RANDOM POSITION PWM

  • Na, Seok-Hwan;Wi, Seok-Oh;Lim, Young-Cheol;Yang, Seung-Hak
    • Proceedings of the KIPE Conference
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    • 1998.10a
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    • pp.316-319
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    • 1998
  • RPWM(Random Pulse Width Modulation) is a switching technique to spread the voltage and current harmonics on the wide frequency area. Using randomly changed switching frequency of the inverter, the power spectrum of the electromagnetic acoustic noise cab be spread to the wide-band area. The wide-band noise is much more comfortable and less annoying than the narrow-band one. So RPWM have been attracting an interest as an excellent method for the reduction of acoustic noise on the inverter drive system. In this paper a new RPPWM (Random Position PWM) is proposed and implemented. Each of three pulses is located randomly in each switching interval. Along with the randomization of PWM pulses, the space vector modulation is executed in the C167 microcontroller also. The experimental results show that the voltage and current harmonics were spread to wide band area and that the audible switching noise was reduced by proposed RPPWM method.

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A Method for Key Generators Using Algorithms in Stream Ciphers (스트림 암호에서 개선된 알고리즘을 이용한 암호 키 발생 방법)

  • 최진탁;송영재
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.14 no.6
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    • pp.604-610
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    • 1989
  • As the volume of communication data and information exchange, the protection of data which we want to keep secret from invalid users would be a main topic nowadays. This paper describes the use of an arbitrary bit-sequence generating algorithm as the cryptographic key for a stream cipher. Emphasis is places on methods for combining stream generators into more complex ones, with and without randomization.

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