• BMB Reports
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• v.54 no.10
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• pp.489-496
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• 2021

Chromatin has highly organized structures in the nucleus, and these higher-order structures are proposed to regulate gene activities and cellular processes. Sequencing-based techniques, such as Hi-C, and fluorescent in situ hybridization (FISH) have revealed a spatial segregation of active and inactive compartments of chromatin, as well as the non-random positioning of chromosomes in the nucleus, respectively. However, regardless of their efficiency in capturing target genomic sites, these techniques are limited to fixed cells. Since chromatin has dynamic structures, live cell imaging techniques are highlighted for their ability to detect conformational changes in chromatin at a specific time point, or to track various arrangements of chromatin through long-term imaging. Given that the imaging approaches to study live cells are dramatically advanced, we recapitulate methods that are widely used to visualize the dynamics of higher-order chromatin structures.

• Journal of Astronomy and Space Sciences
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• v.22 no.2
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• pp.89-112
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• 2005

We determine the rotation velocities of 108 spiral and irregular galaxies (XV-Sample) from first-order rotation curves from position-velocity maps, based on short 21-cm observations with the Westerbork Synthesis Radio Telescope (WSRT). To test the usual random motion corrections, we compare the global HI linewidths and the rotation velocities, obtained from kinematical fits to two-dimensional velocity fields for a sample of 28 galaxies (RC-Sample), and find that the most frequently used correction formulae (Tully & Fouque 1985) are not very satisfactory. The rotation velocity parameter (the random-motion corrected HI linewidth: W?), derived with these corrections, may be statistically equal to two times the true rotation velocity, but in individual cases the differences can be large. We analyse, for both RC- and XV-Samples, the dependence of the slope of, and scatter in the Tully-Fisher relation on the definition of the rotation velocity parameters- For the RC-Sample, we find that the scatter in the Tully-Fisher relation can be reduced considerably when the rotation velocities derived from rotation curves are used instead of the random-motion corrected global H I linewidths. No such reduction in the scatter is seen for XV-Sample. We conclude that the reduction of the scatter in the Tully-Fisher relation seems to be related to the use of two-dimensional velocity information: accurate rotation velocity and kinematical inclination.

• The Journal of the Korea institute of electronic communication sciences
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• v.17 no.2
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• pp.357-364
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• 2022

A pseudo-random number generator (PRNG) is a program used when a large amount of random numbers is needed. It is used to generate symmetric keys in symmetric key cryptography systems, generate public key pairs in public key cryptography or digital signatures, and generate columns used for padding with disposable pads. Cellular Automata (CA), which is useful for specific representing nonlinear dynamics in various scientific fields, is a discrete and abstract computational system that can be implemented in hardware and is applied as a PRNG that generates keys in cryptographic systems. In this paper, I propose an algorithm for synthesizing a programmable 5-neighbor CA based PRNG that can effectively generate a nonlinear sequence using 5-neighbor CA with the radius of the neighboring cell increased by 2.

• Journal of Korean Academy of Nursing
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• v.32 no.2
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• pp.231-242
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• 2002

The purpose of this study was to identify the rate of suicidal attempts, investigate difference of rate of suicidal attempts between students and delinquents, and examine correlation between personality, family dynamics, environment, and suicidal attempts among Korean adolescents. Method: Data were collected through questionnaire surveys. Internal consistencies for this questionnaire ranged from 0.63 to 0.88. The subject used in this study consisted of 922(delinquent : 367, student : 555), using the proportional stratified random sampling method. Statistical methods employed were Chi-square and t-test. Results: \circled1 The rate of suicidal attempts were 10.8%, and the highest peak age of suicidal attempt was 17-18 year old (16.9%). \circled2 Delinquents(19.6%) showed a higher rate of suicidal attempts than students (5.1%). Among the students, girls (43.3%) showed a higher rate of suicidal attempt than boys (19.1%). Whereas, boys (80.9%) showed a higher rate of suicidal attempt than girls (56.7%) among delinquents. \circled3 Those who attempt suicide have more familial problem such as incest, psychosis, depression, attempted suicide, committed suicide, and alcoholism in their family. They also have more dysfunctional family dynamics, environment, and maladaptive personalities than non-attempters. Conclusions: Suicide and suicidal behaviors are multifaceted events. For suicide prevention, independent assessments of variables such as familial problems, personality, family dynamics, and environment must be considered.

• Journal of Advanced Marine Engineering and Technology
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• v.29 no.1
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• pp.60-67
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• 2005

Generally. in the molecular dynamics simulations. the Verlet neighboring list algorithm is used for the reduction of a simulation time On the other hand. the application of the Verlet neighboring list forces the time evolution of a simulation system to follow an unrealistic path in a phase space. In equilibrium state, it does not matter with the simulation results because the individual molecule's motion is originally random and any effect due to a small deviation from a real time evolution can be completely ignored. However, if an unsteady state is involved. such a deviation may significantly affect to the results. That is, there is a Possibility that the simulation results Provide ones with any misleading data In this study we evaluated the effect due to the Verlet neighboring list in performing the simulation of a non-equilibrium state and suggested the method to avoid it.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.19 no.2
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• pp.116-125
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• 2006

We have presented a nanoelectromechanical (NEM) model based on atomistic simulations. Our models were applied to a NEM device as called a nanotube random access memory (NRAM) operated by an atomistic capacitive model including a tunneling current model. We have performed both static and dynamic analyses of a NRAM device. The turn-on voltage obtained from molecular dynamics simulations was less than the half of the turn-on voltage obtained from the static simulation. Since the suspended carbon nanotube (CNT) oscillated with the amplitude for the oscillation center under an externally applied force, the quantity of the CNT-gold interaction in the static analysis was different from that in the dynamic analysis. When the gate bias was applied, the oscillation centers obtained from the static analysis were different from those obtained from the dynamics analysis. Therefore, for the range of the potential difference that the CNT-gold interaction effects in the static analysis were negligible, the vibrations of the CNT in the dynamics analysis significantly affected the CNT-gold interaction energy and the turn-on voltage. The turn-on voltage and the tunneling resistance obtained from our tunneling current model were in good agreement with previous experimental and theoretical works.

• Korean Journal of Materials Research
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• v.16 no.2
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• pp.92-98
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• 2006

Molecular dynamics simulations were performed to study interface structures between an $Al_2O_3$ crystalline phase and a interface phase of $CaAl_2Si_2O_8$. We calculated atomic structures and excess interface energies in systems with different thicknesses of the interface film. It was found that excess interface energies at first readily decreased with increasing film thickness, but increased for larger thicknesses of more than 2 nm. The excess energies of $Al_2O_3/CaAl_2Si_2O_8$ interfaces exhibit a minimum at a thickness around 1 nm. In this range of film thicknesses, the atoms in the interface film show a short-range ordered structure and slow diffusion rather than the random structure and rapid diffusion expected to an observation of an equilibrium thickness for interface films in ceramics.

• Korean Journal of Materials Research
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• v.30 no.2
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• pp.99-104
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• 2020

Recent discoveries of ferroelectric properties in ultrathin doped hafnium oxide (HfO₂) have led to the expectation that HfO₂ could overcome the shortcomings of perovskite materials and be applied to electron devices such as Fe-Random access memory (RAM), ferroelectric tunnel junction (FTJ) and negative capacitance field effect transistor (NC-FET) device. As research on hafnium oxide ferroelectrics accelerates, several models to analyze the polarization switching characteristics of hafnium oxide ferroelectrics have been proposed from the domain or energy point of view. However, there is still a lack of in-depth consideration of models that can fully express the polarization switching properties of ferroelectrics. In this paper, a Zr-doped HfO₂ thin film based metal-ferroelectric-metal (MFM) capacitor was implemented and the polarization switching dynamics, along with the ferroelectric characteristics, of the device were analyzed. In addition, a study was conducted to propose an applicable model of HfO₂-based MFM capacitors by applying various ferroelectric switching characteristics models.

• Ocean Systems Engineering
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• v.6 no.1
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• pp.1-21
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• 2016

The global performance of the 5 MW OC4 semisubmersible floating wind turbine in random waves with or without steady/dynamic winds is numerically simulated by using the turbine-floater-mooring fully coupled dynamic analysis program FAST-CHARM3D in time domain. The numerical simulations are based on the complete second-order diffraction/radiation potential formulations along with nonlinear viscous-drag force estimations at the body's instantaneous position. The sensitivity of hull motions and mooring dynamics with varying wave-kinematics extrapolation methods above MWL(mean-water level) and column drag coefficients is investigated. The effects of steady and dynamic winds are also illustrated. When dynamic wind is added to the irregular waves, it additionally introduces low-frequency wind loading and aerodynamic damping. The numerically simulated results for the 5 MW OC4 semisubmersible floating wind turbine by FAST-CHARM3D are also extensively compared with the DeepCWind model-test results by Technip/NREL/UMaine. Those numerical-simulation results have good correlation with experimental results for all the cases considered.

• Bulletin of the Korean Chemical Society
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• v.17 no.8
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• pp.700-706
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• 1996

We present the results of molecular dynamics simulations of monolayers of long-chain alkyl thiol [S(CH2)15CH3] molecules on an air-solid interface using the extended collapsed atom model for the chain-molecule and a gold surface for the solid surface. Several molecular dynamics simulations have been performed on monolayers with areas per molecule ranging from 18.30 to 32.10 Å2/molecule. It is found that there exist three possible transitions: a continuous transition characterized by a change in molecular configuration without change in lattice structure, a sudden transition characterized by the distinct lattice defects and perfect islands, and a third transition characterized by the appearance of a random, liquid-like state. The analysis of probability distributions of the segments shows that the structure of the chain-molecules at the air-solid interface is completely different from that at the air-water interface in the view of the degree of overlap of the probability distributions of the neighbor segments. The calculated diffusion coefficients of the chain-molecules on the monolayers seem to be not directly related to any one of the three transitions. However, the large diffusion of the molecules enhanced by the increment of the area per molecule may induce the second transition.