• Journal of applied mathematics & informatics
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• 제33권1_2호
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• pp.173-183
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• 2015

A radio k-labeling f of a graph G is a function f from V (G) to $Z^+{\cup}\{0\}$ such that $d(x,y)+{\mid}f(x)-f(y){\mid}{\geq}k+1$ for every two distinct vertices x and y of G, where d(x, y) is the distance between any two vertices $x,y{\in}G$. The span of a radio k-labeling f is denoted by sp(f) and defined as max$\{{\mid}f(x)-f(y){\mid}:x,y{\in}V(G)\}$. The radio k-labeling is a radio labeling when k = diam(G). In other words, a radio labeling is an injective function $f:V(G){\rightarrow}Z^+{\cup}\{0\}$ such that $${\mid}f(x)=f(y){\mid}{\geq}diam(G)+1-d(x,y)$$ for any pair of vertices $x,y{\in}G$. The radio number of G denoted by rn(G), is the lowest span taken over all radio labelings of the graph. When k = diam(G) - 1, a radio k-labeling is called a radio antipodal labeling. An antipodal labeling for a graph G is a function $f:V(G){\rightarrow}\{0,1,2,{\ldots}\}$ such that $d(x,y)+{\mid}f(x)-f(y){\mid}{\geq}diam(G)$ holds for all $x,y{\in}G$. The radio antipodal number for G denoted by an(G), is the minimum span of an antipodal labeling admitted by G. In this paper, we investigate the exact value of the radio number and radio antipodal number for the circulant graphs G(4k + 2; {1, 2}).

• Journal of applied mathematics & informatics
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• 제34권5_6호
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• pp.451-465
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• 2016

A Radio labeling of the graph G is a function g from the vertex set V (G) of G to ℤ⁺ such that |g(u) - g(v)| ≥ diam(G) + 1 - d_G(u, v), where diam(G) and d(u, v) are diameter and distance between u and v in graph G respectively. The radio number rn(G) of G is the smallest number k such that G has radio labeling with max{g(v) : v ∈ V(G)} = k. We investigate radio number for some families of generalized caterpillar graphs.

• Journal of applied mathematics & informatics
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• 제35권1_2호
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• pp.59-74
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• 2017

A radio labeling of a graph G is a function $f:V(G){\rightarrow}\{1,2,{\ldots},k\}$ with the property that ${\mid}f(u)-f(v){\mid}{\geq}1+diam(G)-d(u,v)$ for every pair of vertices $u,v{\in}V(G)$, where diam(G) and d(u, v) are diameter and distance between u and v in the graph G respectively. The radio number of a graph G, denoted by rn(G), is the smallest integer k such that G admits a radio labeling. In this paper, we completely determine radio number of all transformation graphs of a path.

• 한국지능시스템학회논문지
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• 제21권1호
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• pp.138-144
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• 2011

그래프 G = (V, E )의 L(2, 1)-labeling 은 무선통신에서 무선 기기에 할당되는 주파수를 효율적으로 사용하기 위한 최적화 문제로서 NP-complete 계열에 포함되는 문제이다. 본 연구에서는 L(2, 1)-labeling 문제에 적용 가능한 Simulated Annealing 알고리즘을 제시한 후 다양한 그래프에 제시된 알고리즘을 적용하여 그 효용성을 보이고자 한다.

• 대한방사성의약품학회지
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• 제3권1호
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• pp.38-43
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• 2017

Tc-99m labeled sestamibi ($^{99m}Tc$-MIBI) is one of most widely used radiopharmaceuticals for myocardial SPECT imaging. Radiolabeling of $^{99m}Tc$-MIBI is recommended by heating in $100^{\circ}C$ water bath for 15 min. However, the water bath might be a source of contamination. Thus, if radiolabeling of $^{99m}Tc$-sestamibi can be performed at room temperature, then it would be more convenient to use in clinical application. In this study, we performed the radiolabeling of $^{99m}Tc$-MIBI in different temperature conditions or using different instruments to find out the efficient labeling condition. We studied the $^{99m}Tc$-MIBI labeling at room temperature or $100^{\circ}C$ heating block, and checked the labelling yields every 1 min for 10 min using radio-TLC with 2 different eluents-saline and acetone. From the experiment, we confirmed that the $^{99m}Tc$-MIBI can be labeled over 90% yield but not completed at room temperature. However, the $^{99m}Tc$-MIBI labeling was completed when it was performed in the $100^{\circ}C$ heating block. Finally, we proved that heating is essential for complete $^{99m}Tc$-MIBI labelling, furthermore using heating block is also possible instead of water bath.

• 한국식생활문화학회지
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• 제38권6호
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• pp.373-380
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• 2023

In this study, 294 housewives in Siheung, Gyeonggi-do, were surveyed to evaluate the differences in the recognition and use of nutrition labeling according to age and to present data for nutrition education. The younger the age, the more aware the consumer was of the information on the nutrition label. Housewives who were younger than 60 years were more likely to check the nutrition labels. The lower the age, the higher the reliance on the nutritional labeling content of the food, and the higher the recognition level of nutritional labeling. It was found that the lower the age, the easier it was for the consumer to understand the nutritional labeling. Among housewives in their 30s and younger, 89.5 percent said they believed checking nutrition labels would help their health. In the younger age group knowledge and information on nutrition labeling was acquired from the internet, and in the older age group, knowledge was acquired from television, radio, and newspapers. Research conducted on housewives in other regions in the future could provide more detailed information suitable for the population of each region. This would serve as data for nutrition education on the recognition and use of nutrition labeling for a healthy diet.

• 대한약학회:학술대회논문집
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• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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• pp.232.1-232.1
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• 2002

Methods of 14C-radio isotope labeling of quinolone intermediates at four different sites are described. 14C-radio isotope labeled quinolone intermediates can be synthesized from 14C-1-malonic acid, 14C-2-malonic acid, 14C-benzene ring. and 14C-trimethyl orthoformate. The major site of 14C-radio isotope labeled quinolone intermediates is from 14C-2-malonic acid. We want to help customers to choose the best way for synthesis of 14C-radio isotope labeled quinolone derivatives. and give a general comprehension for 14C-radio isotope labeled pharmaceutical compounds. (omitted)

• Archives of Pharmacal Research
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• 제1권1호
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• pp.27-32
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• 1978

A procedure of $^3H$-radio labeling synthesis for the dammarane triterpene glycosides of Korean ginseng was established by using the ginsenoside $Rg_1$ as starting material. The protons in $C-{11}$ and $C_{13}$ of the aglycone moiety of the glycoside were exchanged with tritium by keto-enol tautomerization of 12-keto-ginsenoside $Rg_1$ which was prepared by partial acetylation, Sarett oxidation and saponification, producing nona-acetate, nonaside $Rg_1$. The acety1-ketone and 12-keto-derivative of ginsenotritated ketone was reduced by metallic sodium and isoproponol to produce the end product $^3H$-ginsenoside $Rg_1$ with 3% radio-chemical recovery in one experiment.

• 대한방사성의약품학회지
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• 제3권2호
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• pp.54-58
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• 2017

Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry(MALDI-TOF MS) is one of the powerful methods that enable analysis of small molecules as well as large molecules up to about 500,000 Da without severe fragmentation. MALDI-TOF MS, thus, has been a very useful an analytical tool for the confirmation of synthetic molecules, probing PTMs, and identifying structures of a given protein. In recent nuclear medicine, MALDI-TOF MS liner ion mode helps researcher calculate the average number of chelator(or linkage) per an antibody conjugate, such as DOTA-(or DFO-) trastuzumab for labeling a medical radioisotope. This simple technique can be utilized to improve the labeling method and control the quality at the development of antibody-based radiopharmaceuticals, which is very effected to diagnosis and therapy for in vivo tumor cells, with radioisotopes like $^{89}Zr$, $^{64}Cu$, and 177Lu. To minimize the error, MALDI-TOF MS measurement is repeatedly performed for each sample in this study, and external calibration is carried out after data collection.

• 대한핵의학회:학술대회논문집
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• 대한핵의학회 1999년도 제38차 춘계학술대회
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• pp.193-195
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• 1999

There is considerable interest in $^{188}Re$ due to its favorable properties as a therapeutic radionuclide $^{188}Re$ and $^{99m}Tc$ act as a matched pair because of their similar chemical properties, and therefore methods of labeling with $^{99m}Tc$ can be applied to the labeling with $^{188}Re$. With appropriately chosen agents as carriers of $^{188}Re$, the labeling can be readily carried out using $^{188}ReO_4^-$ in the presence of a reducing agent. $^{188}Re$ radio-pharmaceuticals based on $^{99m}Tc$ complexes have been synthesized and are currently being studied for clinical use. Some of them are shown to be suitable for therapeutic use and promising for radiotherapy in nuclear medicine.