• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2004.04b
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• pp.72-76
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• 2004

본 논문은 CdS의 소성 온도가 방사선 검출 특성에 미치는 영향을 조사하였다. CdS 센서는 스크린 프린터 방식을 이용해 $40{\mu}m$의 두께로 제조하였다. XRD 와 SEM을 이용하여 형성된 CdS 필름의 구조 및 형상을 분석하였다. 제조된 CdS 센서에 대해 X선 반응 특성을 조사하기 위해 I-V 측정을 수행하였다. 인가 전압에 따른 Dark current, x-ray sensitivity 및 선량에 따른 Linearity을 측정한 결과 CdS 센서가 $450^{\circ}C$이상 소성시 방사선에 대한 우수한 검출 특성을 보였다.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.3
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• pp.923-926
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• 2012

The aim of this study was to investigate the early outcome of Endostar combined with chemoradiotherapy for advanced cervical cancer. Fifty-two cases (FIGO IIb to IVa) were divided randomly into two groups, receiving chemoradiotherapy alone (CRT group) and Endostar combined with chemoradiotherapy (CRT+E group). For the patients in the CRT+E group, Endostar was administered daily with the dosage of 7.5 $mg/m^2$, and cisplatin was administered weekly with the dosage of 20 $mg/m^2$ during the radiation. The regimens lasted for 4 weeks with no difference in chemoradiotherapy between the two groups. The early outcome complete remission rate was 73.1%, partial remission rate was 23.1% and the total response rate was 96.2% in CRT+E group, a significant improvement on the 34.6%, 42.3% and 76.9%, respectively, in the CRT group. One year survive rates were 100% and 84.6% in the CRT+E group and CRT groups, the difference being significant. Endostar combined with chemoradiotherapy can improve the early outcome of the advanced cervical cancer, and adverse effects were not encountered.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.14
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• pp.5909-5916
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• 2014

Human papillomavirus infection (HPV) and HPV related immune perturbation play important roles in the development of cervical cancer. Since mature dendritic cells (DCs) are potent antigen-presenting cells (APC), they could be primed by HPV antigens against cervical cancers. In this study we were able to generate, maintain and characterize, both phenotypically and functionally, patient specific dendritic cells in vitro. A randomized Phase I trial with three arms - saline control (arm I), unprimed mature DC (arm II) and autologous tumor lysate primed mature DC (arm III) and fourteen patients was conducted. According to WHO criteria, grade 0 or grade one toxicity was observed in three patients. One patient who received tumor lysate primed dendritic cells and later cis-platin chemotherapy showed a complete clinical response of her large metastatic disease and remained disease free for more than 72 months. Our findings indicate that DC vaccines hold promise as adjuvant sfor cervical cancer treatment and further studies to improve their efficacy need to be conducted.

• Journal of Chest Surgery
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• v.44 no.2
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• pp.159-164
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• 2011

Background: Renal cell carcinoma has shown less response to systemic therapies including chemotherapy, radiation, and immunotherapy than other cancers. Surgery has therefore become an important treatment tool. The protocol for treatment is the same for pulmonary metastasis of renal cell carcinoma. We performed surgery for pulmonary metastatic renal cell carcinomas and analyzed the results. Materials and Methods: We retrospectively analyzed 15 patients who had undergone pulmonary metastasectomy from renal cell carcinoma at our hospital from January 2005 to December 2009. Results: No patients had extrathoracic metastatsis. The mean age was 60.2 years (range 35~73). There were 12 male and 3 female patients. The number of synchronous and metachronous patients were 8 and 7, respectively. The mean survival times of synchronous and metachronous patients were 32.6 and 42.9 months, respectively. 6 patients had single lesions and 9 patients had multiple (more than 3) lesions. The surgical procedures included wedge resection (10), lobectomy (2), wedge resection with segmentectomy (2), and segmentectomy (1). Median observation and survival time were 54.1 and 34.9 months. The 1-year and 3-year survival rates were 80% and 50%, respectively. Conclusion: Pulmonary resection for pulmonary metastatic renal cell carcinoma was found to be a safe and effective treatment modality when complete resection was performed.

• Magazine of the Korean Society of Agricultural Engineers
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• v.36 no.2
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• pp.88-95
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• 1994

This paper is to evaluate the applicability of neural networks to the estimation of evapotranspiration. Two neural networks were developed to forecast daily evapotranspiration of the rice crop with back-propagation and counter-propagation algorithm. The neural network trained by back-propagation algorithm with delta learning rule is a three-layer network with input, hidden, and output layers. The other network with counter-propagation algorithm is a four-layer network with input, normalizing, competitive, and output layers. Training neural networks was conducted using daily actual evapotranspiration of rice crop and daily climatic data such as mean temperature, sunshine hours, solar radiation, relative humidity, and pan evaporation. During the training, neural network parameters were calibrated. The trained networks were applied to a set of field data not used in the training. The created response of the back-propagation network was in good agreement with desired values and showed better performances than the counter-propagation network did. Evaluating the neural network performance indicates that the back-propagation neural network may be applied to the estimation of evapotranspiration of the rice crop. This study does not provide with a conclusive statement as to the ability of a neural network to evapotranspiration estimating. More detailed study is required for better understanding and evaluating the behavior of neural networks.

• Journal of Theoretical and Applied Mechanics
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• v.2 no.1
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• pp.1-14
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• 1996

In this paper, breaking waves are generated in a 2-D wave tank and simulated by using a higher-order boundary element method. A piston-type wavemaker is operated by signals composed of elementary waves. The phase of elementary waves is determined by the linear theory such that they are focused to a prescribed position. Calculated plunging waves coincide well with experiment. A steel box with different plate thicknesses is installed at a predetermined position in the tank. Measured impulsive pressures due to breaking waves are found to be 0.8-1.2$\rho$C2, where $\rho$ corresponds to water density and C to wave celerity. The transverse displacement of the plate is described in terms of modal eigenfunctions. The natural frequencies measured by impact tests in air for thin plate coincide with the computational and theoretical values. The radiationpotential due to plate vibration is derived and the radiation force is expressed in terms of hydroelastic added mass and damping forces. Comparison of natural frequencies of plate in water proves that hydroelastic added mass and damping are properly considered. The measured strain due to regular waves supports the calculated one, but there are apparent discrepancies between theory and experiment in the impulsive case.

• Food Science of Animal Resources
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• v.36 no.1
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• pp.14-18
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• 2016

Oral administration of soluble antigen can induce peripheral tolerance to the antigen. This study was conducted to evaluate whether gamma-irradiated ovalbumin (OVA) can induce oral tolerance. To investigate this, we administrated intact or irradiated OVA to mice, induced allergic response using intact OVA and alum, then compared humoral and cellular immune responses. Mice treated with gammairradiated OVA had less OVA-specific IgE compared with those who were administered intact OVA. There was no difference in levels of OVA-specific IgG+A+M, IgG1, and IgG2a. Splenocytes of mice administered irradiated OVA showed similar OVA-specific T cell proliferation and secretion of IFN-γ and IL-4. However, there was an increase in IL-2 and a decrease of IL-6 secretion in mice treated with irradiated OVA. These results indicate that gamma-irradiated OVA have similar effects to intact OVA on antigen tolerance.

• Steel and Composite Structures
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• v.2 no.6
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• pp.441-460
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• 2002

In the design of bridges, it is important to consider the thermal stresses induced by the non-linear temperature distribution as well as the variation of effective temperature in the bridge deck. To cope with this, design temperature profiles are provided by design codes, which are normally based on extensive research work. This paper presents the results of a comprehensive investigation on the thermal behaviour of bridges in Hong Kong with special emphasis on composite bridges. The temperature distribution in bridges depends primarily on the solar radiation, ambient air temperature and wind speed in the vicinity. Apart from data of the meteorological factors, good estimates of the thermal properties of material and the film coefficients are necessary for the prediction of temperature distribution. The design temperature profiles for various types of composite bridge deck with bituminous surfacing and concrete slab of different thicknesses are proposed. The factors affecting the design effective temperature are also reviewed and suitable values for Hong Kong are proposed. Results are compared with recommendations of the current local code. The method facilitates the development of site-specific temperature profiles for code documents, and it can also be applied to create zoning maps for temperature loading for large countries where there are great climatic differences.

• Bulletin of the Society of Naval Architects of Korea
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• v.19 no.1
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• pp.23-32
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• 1982

Herein the motion of a freely-floating sphere in a water of finite depth is analysed within the framework of a linear potential theory. A velocity potential describing fluid motion is generated by distributing pulsating sources and dipoles on the immersed surface of the sphere, without introducing an inner flow model. The potential becomes the solution of an integral equation of Fredholm's second type. In the light of the vertical axisymmetry of the flow, surface integrals reduce to line integrals, which are approximated by summation of the products of the integrand and the length of segments along the contour. Following this computational scheme the diffraction potential and the radiation potential are determined from the same algorithm of solving a set of simultaneous linear equations. Upon knowing values of the potentials hydrodynamic forces such as added mass, hydrodynamic damping and wave exciting forces are evaluated by the integrating pressure over the immersed surface of the sphere. It is found in the case of finite water depth that the hydrodynamic forces are much different from the corresponding ones in deep water. Accordingly motion response of the sphere in a water of finite depth displays a particular behavior both in a amplitude and phase.

• International Journal of Naval Architecture and Ocean Engineering
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• v.3 no.1
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• pp.20-26
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• 2011

A weakly nonlinear seakeeping methodology for predicting motions and loads is presented in this paper. This methodology assumes linear radiation and diffraction forces, calculated in the frequency domain, and fully nonlinear Froude-Krylov and hydrostatic forces, evaluated in the time domain. The particular approach employed here allows to overcome numerical problems connected to the determination of the impulse response functions. The procedure is divided into three consecutive steps: evaluation of dynamic sinkage and trim in calm water that can significantly influence the final results, a linear seakeeping analysis in the frequency domain and a weakly nonlinear simulation. The first two steps are performed employing a three-dimensional Rankine panel method. Nonlinear Froude-Krylov and hydrostatic forces are computed in the time domain by pressure integration on the actual wetted surface at each time step. Although nonlinear forces are evaluated into the time domain, the equations of motion are solved in the frequency domain iteratively passing from the frequency to the time domain until convergence. The containership S175 is employed as a test case for evaluating the capability of this methodology to correctly predict the nonlinear behavior related to wave induced motions and loads in head seas; numerical results are compared with experimental data provided in literature.