• Title/Summary/Keyword: rabbit

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Hypotensive Action of Atractylodes rhizoma alba Extract (백출(白朮) Extract의 혈압강하작용(血壓降下作用))

  • Ko, Suk-Tai;Su, Se-Min
    • Journal of Pharmaceutical Investigation
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    • v.6 no.2
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    • pp.101-110
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    • 1976
  • 1. In the rabbit and the dog, the blood pressure response to water extract and methanol extract obtained from Atractylodes rhizoma alb'a was investigated. 2. Water extract and methanol extract, when administered into the rabbit and the dog by the route of vein, produced fall of the blood pressure. 3. The depressor response of the rabbit to water extract and methanol extract was not affected by $Avicel{\circledR}$, propranolol and atropine. 4. The depressor response by water extract and methanol extract in the rabbit was not affected by guanethidine, but water extract and methanol extract produced elevation of blood pressure in this rabbit. 5. Pretreatment of rabbit with chlorisendamine or phenoxybenzamine weakened the depressor response to water extract and methanol extract, and the both extracts produced secondary elevation of blood pressure in this rabbit. 6. The pressor response of the chlorisondamine-treated rabbit to water extract and methanol extract was not affected by atropine. 7. Water extract decreased the pressor action of tyramine and depressor action of pilocarpine and isoproterenol, but did not affect the blood pressure response of nor einephrine, angiotensin and dimethylpehnyl piperazinium iodide(DMPP).

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Studies on the Aggregation of H-Y Antibody-Sexed and Bisected Rabbit Embryo (H-Y항체에 의한 토끼배의 성 감별과 이등분 절단 토끼배의 융합에 관한 연구)

  • 최화식;임경순;진동일
    • Korean Journal of Animal Reproduction
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    • v.21 no.2
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    • pp.85-93
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    • 1997
  • These experiments were carried out to examine the development capacity of sexed and then bisected embryo from 8-cell to morula stage. Antisera to histocompatibility-Y(H-Y) antigen were prepared in inbred SD female rat by repeated immunization of spleen cell or testis supernatant from males of same strain. Male and female embryos were separated by delaying development of embryos against H-Y antibody. After sexing, rabbit embryos were bisected and aggregated. The results obtained from the these experiments were summuerized as follows: 1. When mouse and rabbit 8-, 16-cell and morular embryos were culature in H-Y antiserum, the ratio of embryo which has developed to hatching blastocyst was 53.4, 46.3 and 57.4% in mouse embryos, and 49.0, 52.0 and 61.0% in rabbit embryo, respectively. The ratio of mouse and rabbit embryos developed to hatching blastocyst showed nearly natural sex rate(50%), except rabbit mourla showed a little higher ratio(61.0%) as compared to natural sex ratio. 2. When rabbit demi-embryos from 8-, 16-cell embryo and morula were cultured, the percentage of demi-embryos was 70, 68 and 58% without zona pellucida removed, and 62, 69 and 51% with zona pellucida. The rate of aggregation was higher in 8- and 16-cell demi-embryos than in morula demi-embryo. 4. When sexed-demi-embryo was aggregated with another demi-embryo with demi-embryo with same sex, the rate of embryo developed to blastocyst was 60, 50 and 25%, respectively. Eight-cell demi-embryo showed highest rate. In conclusion, it showed that H-Y antiserum which was made by rat spleen cell enabled sexing rabbit embryos. And when rabbit sexed 8-, 16-cell and morula demi-embryo were aggregated, they were developed to eu-blastocyst which suggested the potential of sexed embryo manipulation.

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Establishment of Embryonic Stem Cells Derived from Rabbit Embryos (토끼수정란으로부터 배아세포의 분리)

  • 강회성;임경순;최화식;신영수;진동일
    • Korean Journal of Animal Reproduction
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    • v.25 no.3
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    • pp.219-225
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    • 2001
  • To establish rabbit Embryonic Stem (ES) cells, rabbit one-cell embryos were collected and cultured in vitro to blastocysts. Blastocysts were co-cultured with mouse embryonic fibroblasts (MEF), rabbit embryonic fibroblasts (REF) or 570 cells expressing LIF (SNL). Although rabbit ES cells were isolated with low efficiencies, total 8 ES cell lines were kept in vitro with normal colony shape. The MEF was the best feeder for rabbit ES cell isolation in regard to growth rate and undifferentiated morphology. The doubling time of rabbit ES cells in MEF was about 84 hours and the undifferentiated morphology was maintained following passing and freezing processes. These rabbit ES cells were differentiated into embryoid body following the culture in the uncoated dishes, indicating that they were undifferentiated stem cells.

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Power Analysis Attacks on the Stream Cipher Rabbit (스트림 암호 Rabbit에 대한 전력분석 공격)

  • Bae, Ki-Seok;Ahn, Man-Ki;Park, Jea-Hoon;Lee, Hoon-Jae;Moon, Sang-Jae
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.21 no.3
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    • pp.27-35
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    • 2011
  • Design of Sensor nodes in Wireless Sensor Network(WSN) should be considered some properties as electricity consumption, transmission speed, range, etc., and also be needed the protection against various attacks (e.g., eavesdropping, hacking, leakage of customer's secret data, and denial of services). The stream cipher Rabbit, selected for the final eSTREAM portfolio organized by EU ECRYPT and selected as algorithm in part of ISO/IEC 18033-4 Stream Ciphers on ISO Security Standardization recently, is a high speed stream cipher suitable for WSN. Since the stream cipher Rabbit was evaluated the complexity of side-channel analysis attack as 'Medium' in a theoretical approach, thus the method of power analysis attack to the stream cipher Rabbit and the verification of our method by practical experiments were described in this paper. We implemented the stream cipher Rabbit without countermeasures of power analysis attack on IEEE 802.15.4/ZigBee board with 8-bit RISC AVR microprocessor ATmega128L chip, and performed the experiments of power analysis based on difference of means and template using a Hamming weight model.

Evaluation of the Nutritional Composition and Quality Traits of Rabbit Meat (토끼고기의 영양성분 및 품질특성 평가)

  • Lee, Jeong Ah;Jung, Suk Han;Seol, Kuk-Hwan;Kim, Hyoun-Wook;Cho, Soohyun;Kang, Sun Moon
    • Journal of the Korean Society of Food Culture
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    • v.37 no.2
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    • pp.171-177
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    • 2022
  • This study evaluated the nutritional composition and quality traits of rabbit meat as compared to chicken meat. Samples of loin (M. longissimus dorsi) and breast meats were collected from rabbit and chicken carcasses, respectively. The meats were then analyzed for the proximate composition, collagen and energy contents, fatty acid composition, myoglobin and heme iron contents, pH value, water-holding capacity (WHC), cooking loss, meat color, Warner-Bratzler shear force (WBSF) value, and texture profile. Compared to chicken breast meat, lower (p<0.05) protein content and higher (p<0.05) ash and collagen contents were obtained in rabbit loin meat. Rabbit meat remarkably had higher (p<0.05) total polyunsaturated fatty acids (PUFA) and linolenic acid contents and lower (p<0.05) n-6/n-3 PUFA ratio as compared to chicken meat. The pH value and WHC were lower (p<0.05) in rabbit meat than in chicken meat (p<0.05). Rabbit meat exhibited lower (p<0.05) L* value and higher (p<0.05) a* and b* values compared to chicken meat (p<0.05). The WBSF value, hardness, and gumminess were higher (p<0.05) in rabbit meat than in chicken meat (p<0.05). These findings suggest that rabbit meat has higher essential n-3 PUFA, darker color, and firmer texture as compared to chicken meat.

Neuromodulation on neurogenic contraction of electrical nerve stimulation on isolated renal artery of rabbit (토끼 적출 신동맥에 있어서 전기자극에 의한 신경성 수축작용의 neuromodulation 효과)

  • Kim, Joo-heon;Hong, Yong-geun
    • Korean Journal of Veterinary Research
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    • v.36 no.4
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    • pp.821-828
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    • 1996
  • To elucidate the neuromodulation of neuropeptide Y and $\alpha,\;\beta$-methylene ATP on the neurogenic contraction of electrical perivascular nerve stimulation and the contractile response of noradrenaline from polygraph in the isolated renal artery of rabbit. 1. The neurogenic contraction induced by perivascular nerve stimulation was the voltage-dependent manner(10-100V) in the isolated renal artery of rabbit. 2. Neuropeptide Y(0.1uM) and $\alpha,\;\beta$-methylene ATP(1uM) increased the contractile responses of noradrenaline in the isolated renal artery of rabbit. 3. Neuropeptide Y(0.1uM) and $\alpha,\;\beta$-methylene ATP(1uM) increased the neurogenic contraction of electrical perivascular nerve stimulation in the isolated renal artery of rabbit. These results suggest that neuropeptide Y and $\alpha,\;\beta$-methylene ATP neuromodulated on the neurogenic contraction of electrical perivascular nerve stimulation on the isolated renal artery of rabbit.

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Enhanced Stream Cipher Rabbit Secure Against Power Analysis Attack (전력분석 공격에 안전한 개선된 스트림 암호 Rabbit)

  • Bae, KiSeok;Ahn, MahnKi;Park, YoungHo;Moon, SangJae
    • Journal of the Institute of Electronics and Information Engineers
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    • v.50 no.1
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    • pp.64-72
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    • 2013
  • Recently, stream cipher Rabbit was selected for the final eSTREAM portfolio organized by EU ECRYPT and as one of algorithm in part of ISO/IEC 18033-4 Stream Ciphers on ISO Security Standardization. However, a feasibility of practical power analysis attack to algorithm in experiment was introduced. Therefore, we propose appropriate methods such as random masking and hiding schemes to secure against power analysis attack on stream cipher Rabbit. We implement the proposed method with increment of 24% operating time and 12.3% memory requirements due to maintaining a high-speed performance. We use a 8-bit RISC AVR microprocessor (ATmegal128L chip) to implement our method for practical experiments, and verify that stream cipher Rabbit with our method is secure against power analysis attack.

Chromosomal Analysis of Meiosis and Mitosis in New Zealane White Rabbit (New Zealand White 토끼의 생식세포 및 체세포 분열에 의한 염색체 분석)

  • 신선희;김희수;최영현;이원호
    • Journal of Life Science
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    • v.11 no.4
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    • pp.354-361
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    • 2001
  • Chromosomal characteristics of New Zealane White rabbit was studied at meiosis and mitosis. The meiotic chromosomal preparations were mad with the modified air-drying method and karyotype analysis was performed with the G-banding technique, using isolated mitotic metapase chromosomes of the New Zealand White rabbit. Chromosomes, sex vesicles and centromeres could be classified in the zygotene and the pachytene of the meiosis I. The hair-like processes projecting laterally from the axes of bivalent chromosomes at the mid-to-late pachytene were observed and made the appearance of the lampbrush chromosome structure. Chromosomes could be classified onthe basis of the numbers and locations of chiasma in the diakinesis. Twenty-one autosomal bivalents and a single unequal terminally associated X-Y bivalent were observe during the late prophase and the metaphase of the meiosis I. Most of the bivalent types observed in the New Zealand White rabbit spermatrocytes were 1CH, 1TAl, and 2TA bivalents. The mean chiasma frequency(CF) of the male New Zealand White rabbit was 30.2 and it was found that the CF value tended to decrease through diakinesis and the metaphase I. The karyotype of the New Zealand White rabbit was a male chromosome number of 44(2n=44) comprising 8 pairs of metacentric, 9 pairs of submetacentric, 4 pairs o acrocentric autosomes, metacentric X chromosome and acrocentric Y chromosome.

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Comparison of the Determinants in the Differences in Force-Frequency Relationships between Rat and Rabbit Left Atria

  • Ko, Chang-Mann;Kim, Soon-Jin
    • The Korean Journal of Physiology and Pharmacology
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    • v.4 no.5
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    • pp.417-425
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    • 2000
  • The underlying mechanism commonly applicable for both the positive and negative force-frequency relationships (FFR) was pursued in left atria (LA) of rat and rabbit. The species differences in the roles of $Na^+/Ca^{2+}$ exchanger and sarcoplasmic reticulum (SR), which are major intracellular $Ca^{2+}$ regulatory mechanisms in the heart, were examined in the amplitude accommodation to the frequency that changed from 3 Hz to the variable test frequencies for 5 minutes in the electrically field stimulated left atria (LA) of rat and rabbit. Norepinephrine strongly increased the frequency-related amplitude accommodation in both of rat and rabbit LA, while monensin, oubain or the reduced $Na^+$ and 0 mM $Ca^{2+}$ containing Tyrode solution increased the frequency-related amplitude accommodation only in the rabbit LA. Monenisn was also able to increase the frequency-related amplitude accommodation only in 1-day old rat LA but not in 4-week old rat LA that had 75% less $Na^+/Ca^{2+}$ exchanger with 97% higher SR than 1-day old rat LA. Taken together, it is concluded that the differences in the prevalence between myocardial $Na^+/Ca^{2+}$ exchanger and SR in the amplitude accommodation to the frequency-change determine the difference in the FFR between rat and rabbit heart.

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Simple Electrochemical Immunosensor for the Determination of Rabbit IgG Using Osmium Redox Polymer Films

  • Choi, Young-Bong;Lee, Seung-Hwa;Tae, Gun-Sik
    • Journal of the Korean Electrochemical Society
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    • v.10 no.3
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    • pp.229-232
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    • 2007
  • An amperometric immunosensor for the determination of rabbit IgG is proposed. The immunoassay utilizes a screen-printed carbon electrode on which osmium redox polymer is electrodeposited. This immunoassay detects 0.1 ng/ml of rabbit IgG, which is ${\sim}10^2$ fold higher than the most sensitive enzyme amplified amperometric immunoassay. The assay utilizes a screen-printed carbon electrode which was pre-coated by a co-electrodeposited film of an electron conducting redox hydrogel and a rabbit IgG. The rabbit IgG in the electron conducting film conjugates captures, when present, the anti-rabbit IgG. The captured anti-rabbit-IgG is labeled with horseradish peroxidase (HRP) which catalyzes the two-electron reduction of $H_2O_2$ to water. Because the redox hydrogel electrically connects HRP reaction centers to the electrode, completion of the sandwich converts the film from non-electrocatalytic to electro-catalytic for the reduction of $H_2O_2$ to $H_2O$ when the electrode is poised at 200 mV vs. Ag/AgCl.